Clinical trials
Thyroid Nodule (Benign) clinical trials
Below are recruiting thyroid nodule (benign) clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07237373Recruiting
Heat ablation for benign thyroid nodules
This trial tests a minimally invasive procedure called thermal ablation (using heat) to shrink benign thyroid nodules that cause symptoms like pressure or cosmetic issues, or overactive (hot) nodules. It offers an alternative to surgery or radioactive iodine.
BrugesAges 18 years+ - NCT04666103Recruiting
Study of neck anatomy in thyroid surgery
This study looks at how the structures in the neck affect thyroid surgery outcomes. You may be asked about your diagnosis and pre-surgery neck imaging to better understand surgical safety for people with certain thyroid conditions.
Wuhan, HubeiAges 18–75 - NCT05189314Recruiting
Study of life quality changes with benign thyroid nodules
This study looks at how benign (non-cancer) thyroid nodules affect people’s day-to-day life and health outcomes. It may help doctors better understand what changes matter most to patients.
New York, New YorkAges 18 years+ - NCT05726981Recruiting
Ultrasound check of benign thyroid nodules 3 years after ablation
This study follows people with a benign (non-cancer) thyroid nodule about 3 years after they had a heat-based ablation, using ultrasound and a sample for cytology (cell/tissue review). It aims to see what the nodule looks like long-term and how well these checks track changes.
ParisAges 18 years+ - NCT06225765Recruiting
Scarless thyroid surgery through the mouth vs open surgery
This trial compares a new scarless thyroid surgery (through the mouth) with traditional open thyroid surgery for treating thyroid nodules. It may be an option if you have a benign nodule under 4 cm or a suspicious nodule under 2 cm.
Hong KongAges 18 years+ - NCT06340945Recruiting
Treating benign thyroid nodules with heat
This study uses heat (thermal ablation) guided by ultrasound to shrink benign thyroid nodules that are causing symptoms or cosmetic concerns. It's an option if you can't have surgery or prefer not to.
BeijingAges 18 years+ - NCT06423235RecruitingPhase 4
Prunella oral liquid for thyroid nodules
This trial tests if an herbal liquid made from prunella can shrink benign thyroid nodules. It may be an option for people with solid, non-cancerous nodules who want to avoid surgery.
Chongqing, Chongqing MunicipalityAges 18–65 - NCT06426563Recruiting
Comparing microwave vs radiofrequency for benign thyroid nodules
This study compares two heat-based treatments—microwave ablation (MWA) and radiofrequency ablation (RFA)—for shrinking benign thyroid nodules that are moderate in size. If you have a non-cancerous, solid nodule at least 2 cm wide, this trial may help you avoid surgery.
Hong KongAges 18 years+ - NCT06610604Recruiting
Thyroid nodule treatment and quality of life study
This study looks at how thyroid nodules affect your daily life and feelings after treatment. It compares quality of life in people who had microwave ablation versus those who had thyroid surgery.
Beijing, Beijing MunicipalityAges 18–70 - NCT06729762Recruiting
Ultrasound-guided heat treatment for benign thyroid nodules
This study tests a treatment that uses ultrasound and heat (radiofrequency or microwave) to shrink benign thyroid nodules. It's for people who have a non-cancerous nodule that causes symptoms or worry, and who can't or don't want surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06730321Recruiting
Assessing skills for robotic thyroid surgery
This trial is for people having robotic thyroid surgery (removing all or part of the thyroid with a robot). It aims to create a scoring system to measure how well surgeons perform the procedure. You may be eligible if you have a small thyroid cancer or a benign nodule and want the best cosmetic result.
ShanghaiAges Any age - NCT06779747Recruiting
Comparing thyroid treatment approaches over time
This study looks back at medical records and follows new patients to understand which thyroid treatments work best for different conditions. It includes people with an underactive or overactive thyroid, thyroid nodules, or thyroid cancer.
Bologna, BolognaAges 18 years+ - NCT07046546Recruiting
Thyroid nodule embolization pilot trial
This trial tests a minimally invasive procedure that blocks blood flow to large thyroid nodules, which can shrink them and relieve symptoms like trouble swallowing or cosmetic concerns. It's an option for people with benign nodules or Graves disease who want to avoid surgery or other treatments.
ReadingAges 18 years+ - NCT07226804Recruiting
Pulsed field ablation for benign thyroid nodules
This trial tests a new procedure called nanosecond pulsed field ablation (nsPFA) to shrink benign thyroid nodules that are causing symptoms like tightness in the throat or trouble swallowing.
Houston, TexasAges 18 years+ - NCT05189808Recruiting
Radiofrequency treatment for certain thyroid nodules
This trial studies radiofrequency ablation, a procedure that shrinks a thyroid nodule, for thyroid nodules that are unclear on biopsy but have a reassuring “molecular” test. If you have a Bethesda III nodule that tests benign on specific genetic tests, you may be a good candidate to see if this approach helps safely.
New York, New YorkAges 18 years+ - NCT06146764Recruiting
Better ultrasound for thyroid cancer diagnosis
This study uses a special ultrasound method called contrast-enhanced ultrasound (CEUS) to see if it can improve accuracy of diagnosing thyroid cancer. If you have a thyroid nodule and have had certain tests, this trial may help doctors better understand your condition.
Guangzhou, GuangdongAges 18 years+ - NCT06738888Recruiting
Better predicting easy thyroid removal through mouth or under chin
This study compares two approaches for thyroid removal surgery—one through the mouth and one under the chin—to find which is easier to perform. It is for people with thyroid nodules or early thyroid cancer that hasn't spread.
ShanghaiAges Any age - NCT07488325Recruiting
Using AI to better understand unclear thyroid biopsy results
This study uses artificial intelligence (AI) to look at ultrasound images and cell samples from thyroid nodules that had an unclear biopsy result. The goal is to see if AI can better tell which nodules are cancerous, helping avoid unnecessary surgery in the future.
Guangzhou, GuangzhouAges 18–80 - NCT06868459Enrolling by invitation
Study of PED-TAE treatment for thyroid disease
This study tracks people who have already received a new type of thyroid treatment called PED-TAE (pressure-enabled embolization) using the TriNav system. It aims to see how well this procedure works for various thyroid conditions, including overactive thyroid, large goiters, and benign nodules causing symptoms.
Sarasota, FloridaAges 18–89 - NCT07287176Recruiting
Treating benign thyroid nodules with a new device
This trial tests a new device that uses nanosecond electrical pulses to treat benign thyroid nodules. It may be an option if you have a benign nodule causing symptoms like discomfort or anxiety, and you're looking for a non-surgical treatment.
Sarasota, FloridaAges 22–80 - NCT07140757Recruiting
Radiofrequency ablation for thyroid nodules and low-risk cancer
This trial tests radiofrequency ablation (a heat-based treatment) for people with non-cancerous or suspicious thyroid nodules, or small thyroid cancers. It may be an option if you are not a candidate for or choose not to have surgery.
Houston, TexasAges 18 years+ - NCT05903196Recruiting
Radiofrequency treatment for non-cancer thyroid lumps in LatinX adults
This study looks at radiofrequency ablation, a heat-based procedure, to shrink a benign (non-cancer) thyroid nodule in adults who identify as LatinX. It may help reduce symptoms from the lump while tracking safety and results.
New York, New YorkAges 18–90
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Common questions
- Are there clinical trials for thyroid nodule (benign)?
- Yes. Clin2 currently lists 22 recruiting thyroid nodule (benign) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thyroid nodule (benign) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thyroid nodule (benign) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.