Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 947 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07340931Recruiting
Myopia-control spectacle lenses study for children
This study tests if special Essilor® spectacle lenses can slow down the progression of myopia (nearsightedness) in children. It aims to see if the lenses are comfortable and well-tolerated by young patients.
Nantes, NantesAges 6–16 - NCT07341464Recruiting
Blended tube feeding for children and adults
This study tests if a blended tube-feeding formula made from real food is easy to tolerate and acceptable for people who already use a gastrostomy tube. It may be a good option if you or your child need extra nutrition through a tube.
NottinghamAges 1 year+ - NCT07342881RecruitingPhase 1
Single dose study of pevifoscorvir in people with kidney impairment
This study tests how a single dose of the study drug, pevifoscorvir, is processed in people with different levels of kidney function. It helps understand if the dose needs to be adjusted for people with kidney problems.
Orlando, FloridaAges 18–75 - NCT07345364RecruitingPhase 1
Safety of single dose SIM0811 in healthy adults
This trial tests a single dose of an investigational drug called SIM0811 in healthy Chinese adults. The goal is to see if it's safe and how the body processes it, so researchers can find the right dose for future studies.
Jinan, ShandongAges 18–45 - NCT05946564RecruitingPhase 3
Pioglitazone to protect kidney function in ANCA vasculitis
This Phase 3 trial tests whether pioglitazone can help protect kidney function in people with newly diagnosed or relapsing ANCA-associated vasculitis that is actively affecting the kidneys. It aims to improve “renal tolerance,” meaning your kidneys may be better able to tolerate the disease and treatment.
AmiensAges 18–80 - NCT07024823RecruitingPhase 1
Safety study of AZD4248 in healthy people and those with kidney disease and diabetes
This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.
Glendale, CaliforniaAges 18–75 - NCT07328451RecruitingPhase 1
Study of DNL628 for people with early Alzheimer's disease
This trial tests an experimental drug, DNL628, to see if it is safe and how it affects people with early Alzheimer's disease. It may help slow the disease by targeting a specific process in the brain.
's-HertogenboschAges 18–75 - NCT07347678RecruitingPhase 1
Safety study of RN5681 in healthy volunteers
This trial tests a new drug called RN5681 to see if it is safe and how the body processes it. It is for healthy people with certain cholesterol levels and may help people with high cholesterol or heart risk in the future.
Brisbane, QueenslandAges 18–65 - NCT07352423RecruitingPhase 1
Safety study of ALXN2230 in healthy volunteers
This trial tests the safety and how the body handles a new drug called ALXN2230 in healthy people. It helps find the right dose and checks for side effects.
LondonAges 18–65 - NCT07355270Recruiting
Radiofrequency vapor ablation for type 2 diabetes
This trial tests a new device that uses radiofrequency energy to treat the lining of the upper small intestine in people with type 2 diabetes. The goal is to see if this treatment is safe and helps improve blood sugar control.
Scottsdale, ArizonaAges 22–65 - NCT07359235RecruitingPhase 1
KD01 for bladder cancer: a safety and early efficacy trial
This trial tests a new drug called KD01, which is given directly into the bladder through a catheter (intravesical instillation) for bladder cancer. It aims to see if the drug is safe and tolerable, and if it may help slow or stop the cancer.
Wuhan, HubeiAges 18–75 - NCT07361237RecruitingPhase 1
HJ-004-02 tablet for EGFR-mutated lung cancer
This early-phase trial tests a once-daily tablet (HJ-004-02) for people with a specific type of lung cancer that has an EGFR mutation. It aims to see if the drug is safe and if it can shrink tumors when other treatments have stopped working.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07362459RecruitingPhase 3
Study of SCTB14 for untreated advanced non-small cell lung cancer
This trial tests a new drug, SCTB14, as a first treatment for advanced non-small cell lung cancer that has a high level of PD-L1. It aims to see if the drug is safe and effective for people who haven't had other treatments for their cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07363395RecruitingPhase 1
A study of ASCT-83 in healthy adults
This trial tests a new medication called ASCT-83 in healthy adults to see how safe it is and how the body processes it. It may help researchers understand the right dose for future studies.
Saint Paul, MinnesotaAges 18–64 - NCT07365462RecruitingPhase 2
Study of NBI-1065890 for tardive dyskinesia in adults
This trial tests whether an oral medication, NBI-1065890, can reduce the involuntary muscle movements caused by long-term use of antipsychotic drugs. It is for adults with moderate to severe tardive dyskinesia who also have a stable mental health condition like schizophrenia or bipolar disorder.
Bryant, ArkansasAges 18–75 - NCT07366658RecruitingPhase 1
Experimental therapy for neuroendocrine tumors that did not respond to treatment
This trial tests an experimental therapy (NEUK203-13) for people with neuroendocrine tumors, including small cell lung cancer, that have not responded to or stopped responding to standard treatments. It aims to see if the drug is safe and to look for early signs that it might shrink tumors, especially in people whose tumors have a specific marker called DLL3.
BeijingAges 18–75 - NCT07366866RecruitingPhase 1
Safety study of an experimental drug in healthy adults
This trial tests a new drug, GenSci136, in healthy adults to see if it's safe and how the body processes it. If you qualify, you would receive the drug and be monitored for side effects.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT07371455RecruitingPhase 1
LWP779 safety trial for healthy volunteers
This trial tests a new oral medication called LWP779 in healthy adults to see if it is safe and how the body processes it. It helps determine the right dose for future studies.
AdelaideAges 18–65 - NCT07372703RecruitingPhase 1
Safety study of VV913 capsules in healthy Chinese men
This study tests a new capsule called VV913 in healthy male volunteers to see how safe it is and how the body processes it. It is a first-in-human trial in China to gather basic safety information.
Hefei, AnhuiAges 18–45 - NCT07376642RecruitingEarly Phase 1
Testing IMV101 for relapsed B-cell lymphoma
This study tests an experimental drug called IMV101 for people with certain types of B-cell non-Hodgkin lymphoma that have come back or not responded to other treatments. It aims to see if the drug is safe and if it can shrink tumors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07377175RecruitingPhase 1
Safety study of BSY001 in healthy adults
This early-phase trial tests a single or multiple doses of BSY001 to see if it is safe and how the body handles it. It is for healthy volunteers aged 18 to 50 who are not allergic to similar drugs and can avoid certain medicines and activities during the study.
HangzhouAges 18–50 - NCT07377539RecruitingPhase 1
A study of JZP047 in healthy volunteers
This study tests a new investigational drug called JZP047 in healthy volunteers. Researchers want to see how safe it is, how the body processes it, and whether taking it with food changes its effects.
Lincoln, NebraskaAges 18–55 - NCT07393295Recruiting
TENS for endometriosis-related pain
This trial tests whether a device called TENS can help reduce chronic pelvic pain in people with endometriosis or adenomyosis. It is designed for those who are on stable hormone therapy and willing to limit other pain medications during the study.
BordeauxAges 18 years+ - NCT01906385RecruitingPhase 1/Phase 2
Recurrent brain tumor study testing rhenium nano-liposome
This early-phase study tests a drug made of tiny fat-like particles carrying rhenium for recurrent (coming back) high-grade glioma. It mainly checks safety and the highest tolerable dose, and it also looks for signs the treatment may slow tumor growth.
Manhasset, New YorkAges 18 years+
Hear when a new Tolerance trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 947 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.