Clinical trials
Transplant; Failure, Heart clinical trials
Below are recruiting transplant; failure, heart clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04305717Recruiting
Check fluid levels with a special sensor in hospitalized heart failure
This study uses a noninvasive device (ReDS) to estimate fluid buildup in people hospitalized with acute heart failure. It may help doctors monitor fluid status and guide care more accurately during a hospital stay.
New York, New YorkAges 18 years+ - NCT04438213RecruitingPhase 2
Ertugliflozin for chronic heart failure with added urine testing
This Phase 2 trial studies whether the medication ertugliflozin can help people with chronic heart failure. You would be asked to follow a set treatment plan and complete repeated urine (and other) testing to see how your body responds.
New Haven, ConnecticutAges 18 years+ - NCT04493385Recruiting
Heart transplant after a hepatitis C–positive donor
This trial follows people who receive a heart from a donor whose blood tested positive for hepatitis C. It also includes people getting a heart transplant again, and it aims to learn about outcomes and safety for these specific transplant situations.
Dallas, TexasAges 18 years+ - NCT04554277Recruiting
Blood test-guided care for people hospitalized with heart failure
This study checks whether using a specific blood test (called sST-2) to guide heart-failure treatment leads to better care and outcomes. It may help by tailoring treatment decisions based on your test results.
Montpellier, OccitanieAges 18 years+ - NCT04656080Recruiting
Test heart and lung exercise capacity after transplant
This study uses a treadmill or stationary bike test to measure how well your heart and lungs work after a heart transplant. It may help researchers see whether this type of testing is safe and useful in transplant follow-up.
Dallas, TexasAges 18 years+ - NCT04703842RecruitingPhase 1/Phase 2
Study drug effect on heart muscle calcium in advanced heart failure
This trial tests a treatment intended to improve how heart muscle cells handle calcium, which may help heart failure symptoms and heart function. It is mainly for people with advanced heart failure and a low pumping strength of the heart.
San Diego, CaliforniaAges 18–80 - NCT04848844Recruiting
Congenital heart disease transplant registry study for adults
This study collects and shares anonymous information about adults being considered for a heart transplant because of a congenital (from birth) heart problem or an inherited heart muscle condition. The goal is to better understand these patients and support research that may improve care.
HamburgAges 18 years+ - NCT06526988Recruiting
Heart failure medication optimization study for clinicians and patients
This study tests tools to help doctors and patients work together to start or adjust heart failure medicines. You may qualify if your heart's pumping strength is low and you are missing certain recommended medications.
Walnut Creek, CaliforniaAges 18 years+ - NCT04970888Recruiting
Exercise program to improve thinking and brain blood flow in heart failure
This trial tests whether doing a combined mental (cognitive) and physical exercise program can improve thinking and how well blood flows to the brain in people with chronic heart failure. It may help by strengthening both brain function and physical capacity while your heart condition stays stable.
Montreal, QuebecAges 50 years+ - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT05448833Recruiting
Testing a wireless sensor to monitor left heart pressure
This study tests whether a small wireless sensor can safely measure and track pressure in the left upper heart chamber in people with advanced chronic heart failure. It may help the care team better understand pressure changes that are linked to fluid buildup and symptoms, alongside your usual heart medicines.
Petah TikvaAges 22–88 - NCT05451979Recruiting
Exercise training at home for kids after heart transplant
This trial tests a home-based, short bursts exercise program (HIIT using the MedBIKE™ system) for children who had a heart transplant at least 6 months ago. It may help improve fitness and safety after transplant, while checking which kids can participate without heart rhythm or symptom problems.
Edmonton, AlbertaAges 10–18 - NCT05508256RecruitingPhase 4
Ablation for atrial fibrillation in heart failure with preserved function
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
BerlinAges 18 years+ - NCT05568069Recruiting
Study of defibrillator implants for non-ischemic weak heart
This study looks at whether implantable defibrillators can reduce dangerous heart rhythms in people with non-ischemic cardiomyopathy (heart weakness not caused by blocked heart arteries), a heart scar, and very low pumping strength despite best treatment. It compares different approaches to choosing which patients should receive these devices.
High Wycombe, BuckinghamshireAges 18 years+ - NCT05573997Recruiting
Testing new ultrasound measures of heart muscle function in heart failure
This study looks at whether a special kind of heart ultrasound can better measure how well the heart muscle works in people admitted with heart failure. It may help doctors understand heart function using clearer ultrasound “biomarkers” soon after hospital admission.
Thessaloniki, Central MacedoniaAges 18 years+ - NCT05627440Recruiting
Protein diet program to improve muscle strength in heart failure
This trial tests whether adding dietary protein can help skeletal muscles recover and function better in people living with heart failure. It may help with strength, muscle wasting, and overall ability to do daily activities.
Boston, MassachusettsAges 18–100 - NCT05632432Recruiting
Heart tissue grafts to help the heart after surgery
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Helsinki, UusimaaAges 18–75 - NCT05647213RecruitingPhase 1
Skin biopsy study of stem-cell therapy for congenital heart disease
This early study takes a small skin sample to make a personalized type of heart stem cells in the future. It is testing whether this approach is safe and feasible for people with complex single-chamber congenital heart disease and advanced heart failure.
Rochester, MinnesotaAges 18–40 - NCT05650658Recruiting
Compare two heart pacing options in people with weak heart function
This trial compares two types of “left-side” heart pacing to see which one works better in people with weak heart pumping. It may help guide the best pacing choice for improving heart function and symptoms.
Gilbert, ArizonaAges 18 years+ - NCT05775432Recruiting
Study outcomes for people receiving heart transplants
This study follows people with severe (end-stage) heart failure who are evaluated for and receive a heart transplant. It helps doctors understand what outcomes to expect after transplant, which can guide future care.
Xi'an, ShaanxiAges 3–80 - NCT05873881RecruitingPhase 3
Colchicine and vitamin B1 for ischemic heart failure
This study tests whether colchicine and thiamine (vitamin B1) can improve outcomes in people with heart failure caused by blocked or narrowed heart arteries. It’s mainly for people with moderate-to-severe symptoms and reduced heart pumping ability.
Hamilton, OntarioAges 45 years+ - NCT05873634Recruiting
Using health records and testing to study heart failure types
This study combines electronic health record data and detailed heart testing to better understand different heart failure types and what treatments may work best for each. It mainly enrolls people with known heart failure, and also some people without heart failure for comparison.
Sacramento, CaliforniaAges 30 years+ - NCT05934487Recruiting
Monitoring device trial for stable heart failure symptoms
This trial tests whether a wearable home monitoring system (myCordella™) can help people with moderate heart failure (NYHA class II or III) by tracking heart pressure and supporting follow-up care. It may help detect changes earlier so clinicians can adjust treatment sooner.
Phoenix, ArizonaAges 18 years+ - NCT06081543Recruiting
Ketogenic vs. Mixed Diet for Heart Failure
This study compares a ketogenic (low-carb, high-fat) diet to a standard mixed diet in people with heart failure. It aims to see if the ketogenic diet can improve heart function and symptoms.
Columbus, OhioAges 18–80
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Common questions
- Are there clinical trials for transplant; failure, heart?
- Yes. Clin2 currently lists 270 recruiting transplant; failure, heart studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transplant; failure, heart trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transplant; failure, heart trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.