Clinical trials
Transplant; Failure, Heart clinical trials
Below are recruiting transplant; failure, heart clinical trials, each written for real people, not researchers. We’re tracking 269 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06105580Recruiting
Pacing methods for heart failure with wide QRS
This trial compares two ways to pace the heart in people with heart failure and a wide QRS (a sign the heart's electrical signals are slowed). The goal is to see which method better reduces the risks of death, heart failure hospitalization, or needing a heart transplant.
BarcelonaAges 18 years+ - NCT06205225Recruiting
Mobile health program for heart failure self-care
This study tests a mobile health program (phone app and coaching) to help people with heart failure better manage their condition at home. It aims to improve self-care and reduce hospital visits.
Chicago, IllinoisAges 18 years+ - NCT06253104Recruiting
Tracking muscle changes in acute heart failure
This study measures how thigh muscles change in people hospitalized with severe heart failure. It aims to understand muscle loss during this condition and how it relates to recovery.
Boston, MassachusettsAges 18–100 - NCT06286423RecruitingPhase 4
Colchicine for acute heart failure with low pumping strength
This trial tests if the anti-inflammatory drug colchicine can help people hospitalized with acute heart failure and a weak heart pump. It may benefit those with elevated inflammation markers.
Charlottesville, VirginiaAges 18 years+ - NCT06310031Recruiting
Testing BrioVAD heart pump for severe heart failure
This trial tests a new left-ventricular assist device (LVAD) called BrioVAD for people with advanced heart failure who are not getting enough benefit from medicines. If you qualify, the device is implanted to help your heart pump blood.
Little Rock, ArkansasAges 18–100 - NCT06062966RecruitingPhase 1
Study of anakinra for advanced heart failure on inotrope therapy
This study tests whether a drug called anakinra can improve how your heart responds to inotrope therapy (medicines that help your heart pump). It is for people with advanced heart failure who are already on a steady dose of these medicines and have signs of inflammation. The goal is to see if blocking inflammation helps your heart work better.
Richmond, VirginiaAges 21 years+ - NCT06381427Recruiting
Improving care for older heart patients before surgery
This trial studies whether special care planning before non-cardiac surgery can improve outcomes for older adults with signs of heart stress. If you are 65 or older and scheduled for a moderate- to high-risk surgery, you may be able to join.
GiessenAges 65 years+ - NCT06424288RecruitingPhase 3
Testing vicadrostat plus empagliflozin for heart failure
This study tests whether adding a new study drug called vicadrostat to the standard heart failure medicine empagliflozin helps people with heart failure. It may be a good option if you have heart failure with preserved pumping function and are not already on a medicine called an MRA.
Mobile, AlabamaAges 18 years+ - NCT06426173Recruiting
Strength training for people waiting for a heart transplant
This study tests whether resistance training (strength exercises) can help people waiting for a heart transplant. It is for patients who have been on the transplant list for less than a month and are stable enough to exercise safely.
São Paulo, São PauloAges 18–70 - NCT06473532Recruiting
Text messages to improve heart failure self-care
This study tests whether helpful text messages can improve self-care for older adults with heart failure. If you join, you will receive tailored texts designed to support your heart health routine.
Chicago, IllinoisAges 50 years+ - NCT06479876Recruiting
Home-based heart rehab for heart failure
This study tests a home-based cardiac rehabilitation program for people with heart failure. It aims to help you become more active and manage your condition safely at home.
Nashville, TennesseeAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Phoenix, ArizonaAges 18 years+ - NCT06542822Recruiting
IV iron for non-ischemic heart failure with low iron
This study tests whether intravenous iron can improve outcomes for people with non-ischemic heart failure and low ejection fraction who are also iron deficient. If you fit the criteria, you may receive iron infusions to see if it helps your heart function and symptoms.
Southampton, HampshireAges 18 years+ - NCT06556485Recruiting
Early ablation for heart failure patients with heart pumps or on transplant list
This trial tests whether doing a catheter ablation early (before dangerous heart rhythms start) can help people with severe heart failure who need a heart transplant or already have an ICD. The goal is to see if this can improve outcomes.
Bad OeynhausenAges 18–99 - NCT06576752Recruiting
Home heart failure management after hospital discharge
This trial tests a program to manage heart failure at home after you leave the hospital. It aims to safely adjust your medications to optimal doses while you recover at home.
Lørenskog, AkershusAges 18 years+ - NCT06578520RecruitingPhase 4
Testing dapagliflozin for heart failure on dialysis
This trial tests whether adding dapagliflozin (a medication that helps protect the heart and kidneys) helps people with heart failure who are also on peritoneal dialysis. It may offer extra support for your heart and kidney health.
ValenciaAges 18 years+ - NCT06626685Recruiting
Clonal blood cells in heart failure
This study looks at whether changes in blood cells (called clonal hematopoiesis) are linked to heart failure. By testing your blood, researchers hope to learn more about how heart failure progresses and find new ways to treat it.
BergamoAges 18 years+ - NCT06659952Recruiting
HIV+ donor hearts for HIV+ recipients
This trial tests whether hearts from donors who had HIV can be safely transplanted into people with HIV who need a heart transplant. It may offer a new option for those on the waiting list.
Dallas, TexasAges 18 years+ - NCT06661876Recruiting
Heart radiation therapy for heart failure
This trial tests if a low dose of radiation to the heart can help people with advanced heart failure feel better and improve heart function. It is for patients whose heart failure is stable but severe, and who are already on the best medications.
LeuvenAges 18 years+ - NCT06675448Recruiting
Best practices for heart failure with leaky mitral valve
This trial compares two treatment approaches for people with heart failure and a leaky mitral valve (mitral regurgitation). It aims to find which strategy leads to better outcomes. You may be eligible if your heart function is reduced and you have symptoms despite standard treatments.
Falls Church, VirginiaAges 18–99 - NCT06675552Recruiting
Heart failure medication study in Germany
This study looks at how well heart failure medicines work in people with a specific type of heart failure called HFrEF. It aims to help doctors understand the best way to use these medications.
BerlinAges 18–130 - NCT07687186RecruitingPhase 3
Qishen Yiqi pills for chronic heart failure
This trial tests whether Qishen Yiqi Dripping Pills, a Chinese herbal medicine, can help people with chronic heart failure caused by coronary heart disease. It is for adults who have been on stable heart failure treatment for at least two weeks.
Bozhou, AnhuiAges 18–80 - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Houma, LouisianaAges 18–85 - NCT07447908Recruiting
Understanding worsening heart failure after leaving the hospital
This study monitors heart failure patients after a hospital stay or urgent clinic visit to better understand the signs of worsening heart failure. It may help researchers find ways to predict and prevent future exacerbations.
Newmarket, OntarioAges 18 years+
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Common questions
- Are there clinical trials for transplant; failure, heart?
- Yes. Clin2 currently lists 269 recruiting transplant; failure, heart studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transplant; failure, heart trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transplant; failure, heart trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.