Clinical trials
Tricuspid Valve Regurgitation clinical trials
Below are recruiting tricuspid valve regurgitation clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06183684Recruiting
Study of a new tricuspid valve replacement for severe leakage
This study tests a new, less invasive way to replace the tricuspid valve (the valve between the right upper and lower heart chambers) in people with severe leakage. The valve is delivered through a vein in the neck or leg, avoiding open-heart surgery.
Tucson, ArizonaAges 18–90 - NCT05825898Enrolling by invitation
Treatment outcomes for severe leaking tricuspid valve
This study looks at what happens to adults with moderate-to-severe or severe tricuspid valve “leaking” after different treatment types, such as catheter-based or surgery. It may help doctors understand which approach works best for people with severe valve leakage and symptoms.
Rochester, MinnesotaAges 18 years+ - NCT06814574Recruiting
Pacemaker after tricuspid valve replacement
This study looks at whether people who need a new tricuspid heart valve also need a pacemaker soon after. Researchers want to learn more about heart rhythm changes after valve replacement.
München, BavariaAges Any age - NCT07296016Recruiting
Asia-Pacific mitral and tricuspid valve replacement registry
This study collects information from patients in the Asia-Pacific region who have had or plan to have a procedure to replace a failing mitral or tricuspid valve with a new valve placed inside the old one (called valve-in-valve) or inside a ring that was used in a previous repair (valve-in-ring). The goal is to learn more about how well these procedures work and how they can be improved.
Hong Kong, ShatinAges 21 years+ - NCT06954792Enrolling by invitation
Studying heart changes after tricuspid valve replacement
This study looks at how the heart adjusts after a procedure to replace the tricuspid valve (the valve between the right upper and lower heart chambers). It focuses on patients who need medication to support their blood pressure within 24 hours after the procedure, to better understand and manage this unstable period.
New York, New YorkAges 18 years+ - NCT07243184Recruiting
Polymer heart valve study for mitral valve disease
This trial is testing a new polymer artificial heart valve for people with severe mitral valve problems. It aims to see if this valve is safe and works well during surgical replacement.
BeijingAges 60 years+ - NCT07197736Recruiting
Improving heart ultrasound use at Columbia
This study involves cardiologists who read heart ultrasounds in Columbia's echo lab. It aims to improve how these tests are used to help patients.
New York, New YorkAges 18 years+ - NCT05455489Recruiting
MitraClip registry for severe mitral valve leakage patients
This registry study collects information on people with severe mitral valve leakage (regurgitation) who are treated with the MitraClip G4 device. It aims to better understand which patients benefit most and how well the procedure works in real-world care.
San Donato Milanese, MilanoAges 18 years+ - NCT06455787Recruiting
J-Valve study for leaky aortic valve patients
This study tests a new, less invasive device called J-Valve for people with severe aortic regurgitation (a leaky aortic valve). It is placed through a tube in the leg artery, avoiding open-heart surgery, and may help those who are at high risk for surgery.
Scottsdale, ArizonaAges 18 years+ - NCT07453407Recruiting
Tavi valve vs surgery for severe aortic regurgitation
This trial compares a new catheter-based valve (J-Valve) with open-heart surgery for people with severe aortic regurgitation, a condition where the aortic valve doesn't close tightly. It aims to see which treatment is safer and more effective.
Hefei, AnhuiAges 65 years+ - NCT05667519Recruiting
Ultrasound-guided pacemaker lead placement to prevent valve leak
This trial tests a way to place a pacemaker lead using a special ultrasound view through the esophagus (a transesophageal echocardiogram). The goal is to reduce the chance of developing a serious leak in the tricuspid valve caused by the pacemaker lead.
Munich, BavariaAges 18 years+ - NCT06922526Recruiting
Pacemaker and tricuspid valve health: long-term outcomes
This study looks at how pacemakers and similar heart devices affect the tricuspid valve over time and whether that leads to worse health outcomes. It may help you understand if your device is causing long-term changes.
JinanAges 18 years+ - NCT07334691Recruiting
Trial of a new tricuspid valve replacement device
This trial tests a new catheter-based device to replace your tricuspid valve without open-heart surgery. It's for people with severe tricuspid regurgitation who are at high risk for surgery.
BonnAges 18–85 - NCT02537769Recruiting
Surgery to fix a leaky tricuspid valve in LVAD patients
This study looks at whether fixing a mildly leaky tricuspid valve during LVAD surgery improves outcomes for people with advanced heart failure. It’s mainly aimed at patients who are already scheduled to receive an implantable LVAD.
Seattle, WashingtonAges 18 years+ - NCT07085650Recruiting
Atrial Fibrillation Ablation Study
This study is for people with atrial fibrillation who are planning to have a catheter ablation procedure. It will look at how well the heart works after the procedure and how to prevent future events.
Shenyang, LiaoningAges 18 years+ - NCT07793916Recruiting
Heart device and tricuspid valve function study
This study looks at how heart devices like pacemakers affect the tricuspid valve over time. It uses ultrasound to check valve function and see if the device causes any problems.
Seoul, SeoulAges 19 years+ - NCT06518681Enrolling by invitation
Testing a new polymer heart valve for aortic disease
This trial tests a new type of artificial heart valve made of polymer (a special plastic-like material) for people with severe aortic valve disease. It aims to see if the valve is safe and works well, giving you an option for a replacement valve that might last longer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06836011Recruiting
Heart valve leakage study in a type of amyloid heart disease
This study looks at how common and how serious heart valve leaks are in people with transthyretin amyloid cardiomyopathy (a condition where abnormal protein builds up in the heart). The goal is to better understand these leaks and how they affect long-term health.
Graz, StyriaAges 18 years+ - NCT04913727Recruiting
Testing heart scan predictions after mitral valve repair
This trial studies severe secondary mitral valve leaking and uses heart imaging to predict how well the heart and symptoms improve after a less-invasive valve procedure. It may help doctors better forecast who benefits most from this repair.
BernAges 18 years+ - NCT06951126Recruiting
CT prediction for tricuspid valve repair
This trial looks at how well a computed tomography (CT) scan can predict outcomes for people having a minimally invasive procedure to fix their tricuspid heart valve. If you are getting this procedure, your CT results will be studied to help improve future treatments.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT05310461Recruiting
Early or delayed valve surgery for mixed heart valve disease
This study compares doing aortic valve replacement sooner versus waiting, in people with moderate aortic valve narrowing plus at least moderate leakage in the mitral valve. It aims to see which timing improves heart symptoms and outcomes while keeping treatment safe.
BernAges 18 years+ - NCT03692598Recruiting
Transcatheter repair for leaky tricuspid valve during heart surgery
This trial studies a catheter-based repair to help fix a leaky tricuspid valve (regurgitation), especially when you’re also having another heart surgery. It aims to improve valve function and symptoms while tracking safety and outcomes.
AarhusAges 18–85 - NCT06101888Recruiting
New Heart Valve for Severe Aortic Leak
This study is testing a new, less invasive heart valve system (TaurusTrio) for people with severe aortic regurgitation (a leaky aortic valve) who cannot have open-heart surgery. It aims to see if the valve is safe and works well to improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05747404Recruiting
3D heart ultrasound study for certain right-heart problems
This study uses a special 3D heart ultrasound to measure how well the tricuspid valve and right side of the heart are working. It may help improve how these conditions are evaluated and followed over time.
MilanAges 18 years+
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Common questions
- Are there clinical trials for tricuspid valve regurgitation?
- Yes. Clin2 currently lists 97 recruiting tricuspid valve regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tricuspid valve regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tricuspid valve regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.