Clinical trials
Tricuspid Valve Regurgitation clinical trials
Below are recruiting tricuspid valve regurgitation clinical trials, each written for real people, not researchers. We’re tracking 94 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05747404Recruiting
3D heart ultrasound study for certain right-heart problems
This study uses a special 3D heart ultrasound to measure how well the tricuspid valve and right side of the heart are working. It may help improve how these conditions are evaluated and followed over time.
MilanAges 18 years+ - NCT04084132Recruiting
Testing earlier vs later valve replacement after repaired Tetralogy
This study compares doing a valve replacement earlier versus later in people born with Tetralogy of Fallot who already had heart surgery as babies. It may help decide the safest timing to protect heart function, especially right-sided pumping and valve leakage.
AarhusAges 12 years+ - NCT07726173Recruiting
Off-pump mitral valve repair through the heart
This trial tests a new way to repair a leaky mitral valve without stopping the heart or using a heart-lung machine. The surgery is done through a small cut in the heart's lower chamber. It may be an option for people with severe degenerative mitral regurgitation who are not good candidates for standard open-heart surgery.
Baltimore, MarylandAges 21 years+ - NCT04153292Recruiting
Testing a valve procedure for severe mitral regurgitation
This trial studies a minimally invasive mitral valve repair/replacement approach for people with severe mitral regurgitation (leaky mitral valve) who are not good candidates for standard surgery or catheter options. It may help improve symptoms by treating the leaky valve when other treatments aren’t suitable.
Huntsville, AlabamaAges 18 years+ - NCT07501234Recruiting
Study of the MitraFix® mitral valve repair system
This trial tests a new catheter-based device to fix a leaky mitral valve without open-heart surgery. It is for people whose severe mitral regurgitation puts them at high risk for traditional surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06608823Recruiting
Comparing surgery vs. the Trilogy valve for aortic regurgitation
This trial compares a new less-invasive valve replacement (Trilogy TAVR) with standard open-heart surgery for people with significant aortic regurgitation. It aims to see which treatment works better for patients who are eligible for both procedures.
Burlingame, CaliforniaAges Any age - NCT04408430Recruiting
Valve replacement for severe mitral valve disease in high-risk adults
This trial tests a less-invasive way to treat severe mitral valve problems using a transcatheter valve. It may help people who are too high-risk for standard open-heart mitral surgery by improving symptoms and heart function.
Gilbert, ArizonaAges 18 years+ - NCT06467110Enrolling by invitation
Study of SQ-Kyrin TMVr System for leaky mitral valve
This trial tests a new device called the SQ-Kyrin TMVr System to treat severe mitral regurgitation (a leaky heart valve) in people who are not good candidates for traditional open-heart surgery. The goal is to repair the valve without major surgery, using a catheter-based approach.
Shenyang, LiaoningAges 18 years+ - NCT07442903Recruiting
Tricuspid valve repair with remote pressure monitoring
This trial tests a new way to closely monitor heart function during tricuspid valve repair or replacement. A tiny sensor is placed in your lung artery to track pressure, helping doctors adjust your care remotely.
MunichAges 18 years+ - NCT07171060Recruiting
A study of a new device for leaky heart valve
This trial tests a new device called Laplace TTVR to replace a leaky tricuspid valve in the heart without open surgery. It is for people with severe symptoms despite medical treatment.
Ottawa, OntarioAges 60–90 - NCT04433065Recruiting
Early study of a new catheter valve for tricuspid regurgitation
This trial tests a new “through-the-vein” (catheter) valve procedure to treat leaky tricuspid valve (tricuspid regurgitation) in people who still have symptoms despite best medical therapy. If you qualify, it may help improve valve function and symptoms, while doctors closely track safety and follow-up results.
Birmingham, AlabamaAges 18 years+ - NCT04797572Recruiting
Testing a tool to measure the aortic valve during surgery
This trial evaluates a measuring tool used during aortic valve surgery. It may help surgeons size the valve opening more accurately when treating valve leakage or a dilated (enlarged) ascending aorta.
BrusselsAges 18–80 - NCT04890821Recruiting
Percutaneous ring repair for leaking tricuspid valve
This early study tests a minimally invasive device that helps tighten (repair) the tricuspid valve ring to reduce severe leaking. It may help people who still have symptoms from right-sided heart failure even after taking the best available medicines.
Hackensack, New JerseyAges 18 years+ - NCT06920745Recruiting
TriClip study for severe tricuspid regurgitation
This study is testing whether the TriClip device helps people with severe tricuspid regurgitation (a leaky heart valve) feel better. It compares people who received the TriClip to those who didn't get the procedure.
Santa Clara, CaliforniaAges 18 years+ - NCT06663566Enrolling by invitation
FAPI imaging for right heart function in tricuspid valve leak
This trial uses a special type of PET scan called FAPI to look at how well the right side of your heart is working when you have a leaky tricuspid valve. It may help doctors better understand and manage right heart strain caused by too much blood flow.
Beijing, Beijing MunicipalityAges 18–90 - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT02996552Recruiting
Ring repair for mild-to-moderate leaky right valve
This trial looks at whether adding a specific repair to the right valve (called tricuspid annuloplasty) during mitral valve surgery helps people whose right valve leakage is not severe. It compares doing the extra right-valve repair versus doing only the mitral valve repair.
Rozzano, MilanoAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT03958773Enrolling by invitation
Transcatheter treatment for severe leaking mitral valve
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
KaunasAges 18 years+ - NCT06600191Recruiting
New mitral valve study for leak repair
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
MelbourneAges 18 years+ - NCT06823700Recruiting
Study of SQ-Kyrin device for leaky mitral valve from heart failure
This trial tests a new device (SQ-Kyrin) to fix a leaky mitral valve without open-heart surgery. It is for people with heart failure whose valve leak causes symptoms, and who are not good candidates for traditional surgery.
Valladolid, ValladolidAges 18 years+ - NCT05610566Recruiting
HighLife valve replacement for severe leaking mitral valve
This trial studies a new catheter-based valve replacement system for people with moderate to severe, or severe, mitral valve regurgitation (a leaky mitral valve). It aims to check whether the procedure is safe and can improve heart function compared with expected care.
Suzhou, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for tricuspid valve regurgitation?
- Yes. Clin2 currently lists 94 recruiting tricuspid valve regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tricuspid valve regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tricuspid valve regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.