Clinical trials
Weight Loss clinical trials
Below are recruiting weight loss clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07243054Recruiting
How IV fluids before birth affect newborn weight loss
This trial looks at whether giving IV fluids to mothers before delivery affects how much weight healthy, full-term newborns lose in their first days of life. It is for mothers who feed their baby only formula in the hospital.
Amiens, PicardieAges 18 years+ - NCT05481697Recruiting
Track weight changes and check with a cancer blood test
This study looks at whether closely tracking small, unplanned weight loss—along with a one-time blood test (Galleri)—can help find cancer earlier. It may help people who notice changes in weight without knowing why.
Cleveland, OhioAges 40–80 - NCT06420700Recruiting
Stomach Lining Ablation with Sleeve Gastroplasty for Weight Loss
This study combines two endoscopic procedures to help you lose weight: one that reduces the size of your stomach and one that alters the stomach lining. It is designed for people who are ready to commit to long-term diet changes.
Atlanta, GeorgiaAges 18–65 - NCT06226194Recruiting
Genes and weight loss after bariatric surgery
This study looks at how your genes might affect how much weight you lose after gastric sleeve or gastric bypass surgery. You may be able to help doctors better predict weight loss results for future patients.
Lleida, LeidaAges 18–65 - NCT05806801Recruiting
Study how weight loss changes the body with or without exercise
This study looks at how your metabolism (how your body uses energy and controls blood sugar/fats) changes during weight loss, comparing weight loss alone versus weight loss plus exercise. It may help researchers understand what body changes happen with different approaches and why.
Ann Arbor, MichiganAges 18–40 - NCT06724406Recruiting
Family-centered weight loss for Black adults
This trial tests a weight loss program for Black adults and a family partner. You and a family member work together to lose weight with support from a smartphone or computer.
Chapel Hill, North CarolinaAges 18–75 - NCT07429136Recruiting
Plant-based diet study for weight loss in older adults with obesity
This study tests whether a plant-based, protein-rich diet can help adults aged 55 and older with obesity lose weight. It is designed to see if this diet is both safe and effective for this group.
Amsterdam, South HollandAges 55 years+ - NCT07141342Recruiting
Bed scale weight loss program for wheelchair users
This study tests if using a special bed scale helps wheelchair users lose more weight during a weight loss program. Participants will follow a weight loss plan, and half will get the bed scale to track their weight at home.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04893954Recruiting
Study of spine changes after weight loss from bariatric surgery
This study looks at how rapid weight loss after bariatric surgery may affect your spine over the following year or more. It may help doctors better predict who gets spine-related problems or improvements after surgery.
ParisAges 18 years+ - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT06309238Recruiting
Intensive diet vs. surgery for severe obesity
This study compares two programs for people with severe obesity: an intensive weight-loss diet and a weight-loss surgery (bariatric surgery). It aims to see which approach works better for long-term health.
AarhusAges 18–60 - NCT06410352RecruitingPhase 4
Weight loss methods for longer life with metabolic syndrome
This trial tests weight loss methods in people with type 2 diabetes, high blood pressure, and excess weight. It aims to see if losing 15-20% of body weight can help people live longer and healthier.
Astana, AstanaAges 35–65 - NCT06423599RecruitingPhase 2/Phase 3
Weight Loss for Obesity and Heart Failure
This study tests whether weight loss from a medication can improve how you feel, move, and how well your heart works. It's for people who have both obesity and heart failure with reduced pumping strength.
CopenhagenAges 18 years+ - NCT04839614Recruiting
Weight-loss surgery plus uterus surgery for certain uterine lining conditions
This trial tests doing weight-loss surgery at the same time as laparoscopic uterus (womb) surgery for people with certain early uterine lining conditions. It may help lower risk from severe obesity while treating the uterine condition.
Boston, MassachusettsAges 18 years+ - NCT04812314Recruiting
Study how exercise changes body fat and metabolism
This study looks at how starting exercise changes the structure and function of body fat. It may help you understand how exercise affects things like cholesterol and blood sugar, even if you’re not currently exercising regularly.
Ann Arbor, MichiganAges 18–40 - NCT06112964Recruiting
Brain and behavior changes in cancer-related weight loss
This study looks at changes in thinking, behavior, and brain structure that can happen when people with cancer lose weight and appetite (called cachexia). Researchers will use questionnaires and brain scans to understand these changes, which may help improve care for people with cancer.
CambridgeAges 18 years+ - NCT07015424Recruiting
TORe procedure vs lifestyle changes for weight regain after bypass
This study compares a procedure called TORe (a way to reduce the size of your stomach opening) combined with lifestyle changes versus lifestyle changes alone to help people who have regained weight after gastric bypass surgery. The goal is to see which approach works better for long-term weight control.
Irvine, CaliforniaAges 18 years+ - NCT05982132Recruiting
Weight changes in men starting prison in Martinique
This study looks at how weight changes in men who are newly locked up in a Martinique prison. If you join, researchers will track your weight over time to understand what happens.
DucosAges 18–44 - NCT06491537Recruiting
Time-restricted eating for losing weight after having a baby
This study tests whether eating only during a specific daily window (time-restricted eating) helps new moms lose weight. It may be an option if you are 6 to 16 weeks postpartum and have a body mass index (BMI) of 25 or higher.
Birmingham, AlabamaAges 18 years+ - NCT06967389Recruiting
Helping kids with severe obesity reduce heart risks
This trial tests whether semaglutide can lower heart disease risks in children with extreme obesity. It aims to improve weight and heart health over time.
Lexington, KentuckyAges 12–17 - NCT06575738RecruitingPhase 1
Semaglutide for teens after weight-loss surgery
This study looks at how teenagers and young adults respond to weight-loss surgery (sleeve gastrectomy) and whether adding a medication called semaglutide can help improve weight loss. It has two parts: first observing how surgery affects you, then testing if semaglutide helps those who didn't lose enough weight after surgery.
Aurora, ColoradoAges 12–24 - NCT06989203Recruiting
Protein supplement study for body weight
This trial tests how protein supplements affect body weight in people who are either normal weight or overweight. The goal is to see if adding protein helps with weight management.
Hangzhou, ZhejiangAges 20–50 - NCT05725967Enrolling by invitation
Endoscopic and bariatric procedures for obesity
This study looks at people who are having obesity-related procedures, including options done with a scope (endoscopic) and revision after prior bariatric surgery. It may help doctors understand outcomes and improve care for people undergoing these treatments.
Boston, MassachusettsAges 18–80 - NCT03840733Enrolling by invitation
Study linking meal timing and habits to weight loss
This study looks at how timing of daily behaviors (like eating) relates to how much weight people lose during a behavioral weight loss program. You may be asked to track your activity with wearable devices and to do body-metabolism testing using urine samples and special water.
Aurora, ColoradoAges 18–60
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Common questions
- Are there clinical trials for weight loss?
- Yes. Clin2 currently lists 194 recruiting weight loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weight loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.