Clinical trials
Weight Loss clinical trials
Below are recruiting weight loss clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06193577Recruiting
White kidney bean extract for weight and metabolism
This trial tests whether a dry extract from white kidney beans (Phaseolus vulgaris) can help men with overweight or mild obesity lose weight and improve metabolic health. Participants will follow a diet and take the extract or a placebo for a few weeks.
Catania, CataniaAges 18–60 - NCT07419854RecruitingPhase 4
Restoring facial fullness after GLP-1 weight loss with Radiesse
This trial tests whether a facial filler called Radiesse can restore volume lost during weight loss from GLP-1 medications (like Wegovy or Mounjaro). It's for adults just starting GLP-1 therapy who expect to lose 20 pounds or more and want to see if fillers can help their face look fuller.
Pasadena, CaliforniaAges 21–65 - NCT07239167Enrolling by invitation
Weight change study for adults with obesity
This study looks at how weight changes affect health in adults with obesity. You may qualify if you have a high BMI and are willing to try a weight loss program.
Taipei, Zhongzheng DistAges 18 years+ - NCT03123835Enrolling by invitation
Testing POEM and other procedures for reflux and swallowing problems
This trial studies how well POEM and other endoscopy-based (through-the mouth) treatments work for conditions like acid reflux, achalasia (trouble moving food), and Barrett’s esophagus. It may help doctors compare outcomes and choose the safest, most effective procedure for your situation.
Sacramento, CaliforniaAges 18–80 - NCT02043457Recruiting
Study factors that predict long-term weight loss success
This study looks for traits (like health measurements or medical factors) that can help predict who will successfully lose weight and keep it off. It may help researchers personalize weight-loss plans in the future.
Ann Arbor, MichiganAges 15–75 - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
Birmingham, AlabamaAges 18 years+ - NCT04453072Recruiting
iPhone weight-loss app for teens and young adults after transplant
This study tests whether an iPhone weight-management app can help adolescents and young adults lose weight after a stem cell transplant. If you qualify, you’ll use the app and the team will track changes in weight.
Los Angeles, CaliforniaAges 13–30 - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT06339840Recruiting
Lifestyle change for weight and fertility in obese men
This study tests whether a lifestyle program (diet and exercise) can help men with obesity lose weight and improve their chances of fathering a child through fertility treatment. You and your partner can join if you are an obese male, your partner has a healthy weight and regular periods, and you are both planning treatment at our center.
Zhengzhou, HenanAges 22–40 - NCT07513168RecruitingPhase 4
Low-dose semaglutide for weight loss in obese adults
This study tests whether a low dose of semaglutide (a once-weekly injection) can help obese adults without diabetes lose weight. Semaglutide works by reducing appetite and helping your body use food differently.
Hyderābād, SindhAges 18 years+ - NCT05925959Recruiting
Weight loss before abdominal hernia surgery
This trial studies whether losing weight before open abdominal wall hernia repair is safe and helpful for recovery. It may help your surgeon plan the operation more effectively, especially when a complex technique (with mesh and muscle release) is expected.
Chicago, IllinoisAges 18 years+ - NCT05780814Recruiting
Treating insomnia to improve weight loss after breast cancer
This study looks at whether improving insomnia (trouble falling asleep or staying asleep) can help survivors of breast cancer lose weight more successfully through a structured behavioral weight loss program. It may help if sleep problems are making it harder to change eating and activity habits.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06455878Recruiting
Mobile app for weight loss in heart failure patients
This trial tests a mobile app that helps you track your diet to manage your weight. It is designed for people with heart failure who are overweight and have recently been in the hospital for their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05170919Enrolling by invitationPhase 2
Olanzapine vs mirtazapine for weight loss in advanced cancer
This Phase 2 study tests whether the medicines olanzapine or mirtazapine can help people with advanced cancer who are losing weight without trying. It looks at improving unintentional weight loss when standard cancer care is also ongoing.
Englewood, New JerseyAges 18 years+ - NCT06244888RecruitingPhase 2
Using new strategies to help maintain weight loss
This study tests a method to help people who have already lost weight keep it off. It uses a control systems engineering approach to provide personalized support.
Providence, Rhode IslandAges 18–70 - NCT02604563Recruiting
Aging, blood changes, and health in older adults
This study examines why some older adults develop changes in their blood cells that may affect their health. Researchers will look for links between these blood changes, aging, and common health problems in older people.
St Louis, MissouriAges 50 years+ - NCT06937177RecruitingPhase 2
Testing mifomelatide to help maintain weight during chemo
This trial tests an investigational drug called mifomelatide (TCMCB07) to see if it can help people with newly diagnosed colorectal or pancreatic cancer maintain a healthy weight while receiving certain types of chemotherapy. You would give yourself a daily injection under the skin.
Tucson, ArizonaAges 18 years+ - NCT07318727Recruiting
Diet study for weight loss in overweight endometrial cancer patients
This study tests if specific diet changes can help overweight women with endometrial cancer or atypical hyperplasia lose weight while undergoing fertility-sparing treatment.
BeijingAges 18–40 - NCT07714018Recruiting
Comparing two weight loss programs for kidney cancer patients
This study tests two different weight loss programs to see which one helps prevent kidney cancer from growing in people with small kidney masses who are under active surveillance. It may help by improving overall health and potentially slowing cancer progression.
Buffalo, New YorkAges 18 years+ - NCT07837973RecruitingPhase 2
Medicine to maintain weight loss after weight-loss shots
This study tests a new medicine called ALV-100 to see if it can help people who have already lost weight with a weight-loss injection or pill keep the weight off. You must be currently on a stable weight-loss medicine and have lost at least 10% of your body weight to join.
Birmingham, AlabamaAges 18–75 - NCT01344525Recruiting
Study of team-based therapy for obesity and weight loss
This study looks at an interdisciplinary, team-based obesity treatment plan and how well it helps people lose significant weight over time. You might be a candidate if you are an adult with obesity who already achieved more than 10% weight loss within about 6 months from a lifestyle program or weight-loss surgery.
HeidelbergAges 18–65 - NCT05472922Recruiting
Small stomach bypass surgery for weight loss
This trial compares a “mini” gastric bypass procedure to help with weight loss in adults who qualify for bariatric (weight-loss) surgery. It’s testing whether the approach works well and is safe for people who meet the study requirements.
AlmeloAges 18 years+ - NCT04721873RecruitingPhase 2
Weight-loss medicine for people with ulcerative colitis
This study tests whether a weight-loss medication, along with usual ulcerative colitis care, can help people who have both ulcerative colitis and obesity. It focuses on people with active symptoms or who need ongoing steroid medicine, and it also checks safety with heart, blood, infection, and mental-health screenings.
La Jolla, CaliforniaAges 18–80 - NCT05987631Recruiting
Predicting weight loss and health after weight loss surgery
This study looks at why some people lose more weight and improve their health more than others after bariatric surgery. It also has a subgroup that specifically studies people who are insulin resistant (a sign of prediabetes) to see how surgery affects their metabolism.
Gouda, South HollandAges 18–75
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Common questions
- Are there clinical trials for weight loss?
- Yes. Clin2 currently lists 181 recruiting weight loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weight loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.