Clinical trials
Weight Loss clinical trials
Below are recruiting weight loss clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06244888RecruitingPhase 2
Using new strategies to help maintain weight loss
This study tests a method to help people who have already lost weight keep it off. It uses a control systems engineering approach to provide personalized support.
Providence, Rhode IslandAges 18–70 - NCT02604563Recruiting
Aging, blood changes, and health in older adults
This study examines why some older adults develop changes in their blood cells that may affect their health. Researchers will look for links between these blood changes, aging, and common health problems in older people.
St Louis, MissouriAges 50 years+ - NCT06937177RecruitingPhase 2
Testing mifomelatide to help maintain weight during chemo
This trial tests an investigational drug called mifomelatide (TCMCB07) to see if it can help people with newly diagnosed colorectal or pancreatic cancer maintain a healthy weight while receiving certain types of chemotherapy. You would give yourself a daily injection under the skin.
Tucson, ArizonaAges 18 years+ - NCT07318727Recruiting
Diet study for weight loss in overweight endometrial cancer patients
This study tests if specific diet changes can help overweight women with endometrial cancer or atypical hyperplasia lose weight while undergoing fertility-sparing treatment.
BeijingAges 18–40 - NCT07757087RecruitingPhase 1
Study on energy use after weight loss
This study tests a new medicine to see how it affects the body's energy use after losing weight. It compares the medicine to a low-calorie diet or a placebo (a pill with no active ingredient) in adults with obesity.
Aarhus NAges 18 years+ - NCT06681246Recruiting
How gut bacteria affect weight regain after weight loss
This study looks at how the natural bacteria in your gut (the microbiome) might be linked to regaining weight after losing it. It tests whether a short course of antibiotics or a placebo (a sugar pill) affects this process. The goal is to find new ways to help people keep weight off long-term.
RehovotAges 18–65 - NCT03824652RecruitingPhase 2
Walnuts and omega-3 to help weight loss before prostate surgery
This Phase 2 study tests whether adding walnuts (and related nutrients like omega-3s) can help with weight loss and energy in people with prostate cancer who are planning prostate removal surgery. It aims to see if diet changes improve how you feel and manage weight before and around treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT06147843Recruiting
Study on weight loss in ALS patients from France and Germany
This study looks at why some people with ALS lose weight and what factors are involved. It follows patients in France and Germany to better understand weight changes and help improve care.
LilleAges 18 years+ - NCT05608772Recruiting
Revision weight-loss surgery after failed sleeve
This study looks at which revision surgery works best after a prior sleeve stomach operation that didn’t last. It tests switching to one of three procedures to help with weight regain, and it excludes more severe acid reflux cases.
Alexandria, Alexandria GovernorateAges 18–60 - NCT06717334Recruiting
Lung cancer screening for people with unexplained weight loss
This study tests if low-dose CT scans can find early lung cancer in people who have unexplained weight loss. It aims to see if weight loss could be a sign that makes screening more useful.
Basking Ridge, New JerseyAges 50–80 - NCT07195708Recruiting
Orbera365 Balloon for Weight Loss
This trial tests an intragastric balloon (Orbera365) to help people with obesity lose weight. The balloon is placed in your stomach for up to 12 months. The study will see if it is safe and effective when combined with diet and behavior changes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07092618RecruitingPhase 2/Phase 3
Trial for keeping weight off after stopping GLP-1 meds
This study tests if other medicines (naltrexone, metformin, or rapamycin) can help people keep off weight they lost while taking GLP-1 drugs like Wegovy or Ozempic, after they stop taking them. It is for AgelessRx patients aged 40 to 85 who have lost at least 15 pounds on GLP-1s.
Chicago, IllinoisAges 40–85 - NCT07302802Recruiting
Semaglutide for weight loss in teens with genetic obesity
This trial studies whether semaglutide (a once-weekly injection) helps adolescents with a specific genetic form of obesity lose weight. It is for teens who are already being prescribed semaglutide as part of their regular care.
ParisAges 12–21 - NCT06843512Recruiting
How GLP-1 meds change eating habits
This study looks at how starting a GLP-1 medication (like Wegovy or Ozempic) changes your food choices and eating habits. It may help you understand if these medicines work for weight loss.
State College, PennsylvaniaAges 18 years+ - NCT06988150Recruiting
SIBO and weight loss in pancreatic cancer
This study looks at whether a condition called SIBO (too many bacteria in the small intestine) is linked to weight loss in people with pancreatic cancer. You might join if you have pancreatic cancer and have lost weight recently.
Los Angeles, CaliforniaAges 18 years+ - NCT05930483Recruiting
Remote weight loss program for Hispanic/Latina breast cancer survivors
This trial tests a community-style, online (remote) weight loss program for people who finished breast cancer treatment and are now trying to improve health and weight. It may help by supporting safer weight loss through diet/energy reduction and physical activity.
Seattle, WashingtonAges 18 years+ - NCT06518837RecruitingPhase 2
Tirzepatide for weight loss in early breast cancer
This study tests if tirzepatide (a weight loss drug) can help women and men with early-stage hormone receptor-positive breast cancer who are overweight or obese. The goal is to see if losing weight can improve outcomes after completing their initial breast cancer treatment.
Elizabeth, New JerseyAges 18 years+ - NCT06565104Recruiting
Sleep study for people with high blood pressure
This study tests whether improving sleep can lower blood pressure. It is for people with elevated blood pressure or hypertension who speak English or Spanish.
New York, New YorkAges 20 years+ - NCT07720414Recruiting
GLP-1 Meds and Breastfeeding Study
This study tests whether a type of diabetes/weight loss medication (GLP-1 RA, given as a shot) affects milk production in breastfeeding mothers. It may help women who need this medicine while nursing.
Aurora, ColoradoAges Any age - NCT07642245Recruiting
Pilates and aerobic exercise for postpartum weight loss
This study tests whether Pilates and moderate aerobic exercise help women lose weight and improve body composition after giving birth. If you're interested in structured exercise during recovery, this trial may help you achieve safe, sustainable results.
Lahore, Punjab ProvinceAges 20–40 - NCT05472922Recruiting
Small stomach bypass surgery for weight loss
This trial compares a “mini” gastric bypass procedure to help with weight loss in adults who qualify for bariatric (weight-loss) surgery. It’s testing whether the approach works well and is safe for people who meet the study requirements.
AlmeloAges 18 years+ - NCT06658912Recruiting
Weight loss program for breast cancer survivors
This study tests a weight loss program designed specifically for women who have finished breast cancer treatment. It aims to help improve overall health after cancer.
Durham, North CarolinaAges 21–90 - NCT07619989Recruiting
Ear nerve stimulation for weight loss after tirzepatide
This trial tests if a gentle electrical stimulation to the ear can help people who haven't lost much weight with tirzepatide (a diabetes/weight drug). It's for people who are still overweight after 12 weeks of treatment.
Nanjing, JiangsuAges 18–50 - NCT03868592Recruiting
Weight loss study in people with very high body weight
This trial looks at how to support long-term weight loss and improve how your body handles fat breakdown. It may help people who have severe obesity after bariatric (weight-loss) surgery, but it has several health and lifestyle limits.
Rochester, MinnesotaAges 18–65
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Common questions
- Are there clinical trials for weight loss?
- Yes. Clin2 currently lists 194 recruiting weight loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weight loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.