Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT06338735Recruiting
High-frequency ultrasound for Sjögren's diagnosis
This study uses a special, very high-frequency ultrasound to take detailed images of the small glands that can be affected in Sjögren's syndrome. The goal is to see if this new ultrasound technique can help doctors diagnose Sjögren's more accurately.
PisaAges 18 years+ - NCT06450977Recruiting
MIND diet study for people with multiple sclerosis
This study tests whether the MIND diet (a combination of the Mediterranean and DASH diets) can help people with multiple sclerosis (MS). Participants will receive meals and be monitored remotely, so you can take part from home.
Urbana, IllinoisAges 18–64 - NCT06466889Recruiting
Mastocytosis Registry of Zurich
This study is a registry (a simple data collection) for people with mastocytosis or hypertryptasemia who are treated at the University Hospital of Zurich. It aims to gather information to better understand these conditions and improve care.
ZurichAges Any age - NCT06475469Recruiting
Immune system in untreated CLL and infection risk
This study looks at how the immune system works in people with untreated CLL and tries to find ways to predict who might get infections. It aims to help doctors better protect patients from infections in the future.
ReimsAges 18 years+ - NCT06477549RecruitingPhase 2
Comparing Two Drug Combinations for Stem Cell Transplant
This study compares two different drug combinations (BeFluBu and FluBuRux) used before a stem cell transplant from a half-matched (haploidentical) donor. The goal is to see which combination works better to prepare your body for the transplant and control your blood cancer.
Saint PetersburgAges 18–75 - NCT07819097RecruitingPhase 3
RSV vaccine study for healthy older adults
This study tests an RSV vaccine to see if it is safe and helps your immune system fight the virus. It's for older adults who are generally healthy, and it may help protect you from severe RSV illness.
Scottsdale, ArizonaAges 60 years+ - NCT06478537RecruitingPhase 2
Hetrombopag for Immune Tolerance in ITP After Platelet Recovery
This study tests whether a drug called hetrombopag can help your immune system stop attacking your platelets, so your platelet count stays up even after stopping the drug. It's for people with ITP who responded well to hetrombopag but want to see if they can stay in remission without it.
Beijing, Beijing MunicipalityAges 18–50 - NCT05029531RecruitingPhase 3
Immuno-chemotherapy for infants with B-lineage ALL
This trial tests a combination of medicines (immunotherapy plus chemotherapy) in babies diagnosed with a type of leukemia called B-lineage acute lymphoblastic leukemia (ALL). It aims to improve how well treatment works and is delivered safely in very young children.
Moscow, Samory-Mashela,1Ages 1 day–12 months - NCT05546138Recruiting
Study for early diabetic nerve damage in people with diabetes
This trial looks for and studies early nerve problems in the feet or legs that can happen with diabetes, before nerve damage is clearly diagnosed. It may help doctors better predict who is at risk and understand early changes.
AalborgAges 18–60 - NCT06479317Recruiting
Combining hydroxychloroquine and dexamethasone for ITP with positive ANA
This trial tests if adding hydroxychloroquine (HCQ) to the steroid dexamethasone (DEX) works better than dexamethasone alone for adults with immune thrombocytopenia (ITP) who have a positive antinuclear antibody (ANA) blood test. The goal is to see if this combination can safely raise platelet counts and reduce bleeding risk.
Shanghai, Shanghai MunicipalityAges 15–75 - NCT07817641Recruiting
Proton therapy for lymphoma in the chest
This trial tests proton therapy, a precise type of radiation, to treat lymphoma in the chest. The goal is to reduce damage to healthy organs while still curing the cancer.
Copenhagen, Select A StateAges 18 years+ - NCT07822776RecruitingPhase 2
Efgartigimod for anti-NMDA receptor encephalitis
This trial tests a drug called efgartigimod, which may help people with anti-NMDA receptor encephalitis, a condition where the immune system attacks the brain. The study aims to see if it can improve symptoms when added to standard steroid treatment.
BeijingAges 18 years+ - NCT07824479Recruiting
Pre-surgery immunotherapy for advanced stomach cancer
This study tests whether giving immunotherapy before surgery can help shrink advanced stomach cancer and improve outcomes. Immunotherapy uses your body's own immune system to fight cancer cells.
ShanghaiAges 18–80 - NCT07819747Recruiting
Asthma support program for families and schools
This program gives families, schools, and doctors extra resources to help manage a child's asthma. It aims to improve how children with asthma feel and reduce school visits for breathing problems.
St Louis, MissouriAges 3–18 - NCT07823842Recruiting
Biologics for asthma and COPD
This study looks at how well medicines called biologics work for people with asthma or COPD. Biologics are special shots that target certain parts of the immune system to reduce inflammation. Researchers want to see if these treatments can help control symptoms and prevent flare-ups.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07822100Recruiting
Personalized treatment for IgA nephropathy and IgA vasculitis
This trial tests a personalized approach that uses a blood test to help guide targeted therapies for IgA nephropathy and IgA vasculitis. It may help reduce kidney damage and control the disease with fewer side effects.
Beijing, Beijing MunicipalityAges 18–75 - NCT07823478Recruiting
Home urine testing for lupus patients
This study tests whether lupus patients can use a home urine test to monitor their kidney health, which could help catch kidney problems early. It is for patients who have lupus and may have had kidney involvement before, or are at risk of developing it.
New York, New YorkAges 18 years+ - NCT05713448Recruiting
Check how common overweight is in adults with type 1 diabetes
This study looks at how many adults with type 1 diabetes have overweight or obesity. It may help improve future care planning for people living with type 1 diabetes.
LeuvenAges Any age - NCT06482684RecruitingPhase 2
CAR-T cell therapy for new, high-risk mantle cell lymphoma
This study tests a type of immunotherapy called CAR-T cells (modified immune cells) for people with untreated, high-risk mantle cell lymphoma. It aims to see if this therapy can help control the disease early on.
MainzAges 18–75 - NCT06461481Recruiting
Follow-up strategies for de-escalating multiple sclerosis treatment
This study tests different ways of monitoring people with relapsing-remitting MS who are reducing or stopping their medication. It aims to find the safest follow-up approach and may help guide future treatment decisions for those with stable disease.
DüsseldorfAges 18 years+ - NCT06394063Recruiting
Telitacicept to prevent lupus flares
This trial tests a medicine called Telitacicept to see if it can prevent lupus flares in people whose disease is currently mild or stable. It may be a good option if you want to keep your lupus under control and avoid sudden worsening.
ShanghaiAges 18–70 - NCT05010902Recruiting
Pregnancy and MS study for people 18 and older
This study follows people with multiple sclerosis (MS) or a related condition to learn how pregnancy affects MS. You may be asked to complete health questionnaires and get MRI scans, which can help researchers understand what changes during pregnancy.
BerlinAges 18–50 - NCT05636787RecruitingPhase 2
Treosulfan chemo for myeloma before stem cell transplant
This trial tests whether the chemotherapy medicine treosulfan (Trecondi® Ideogen) works well and is safe for people with myeloma who are moving on to high-dose chemotherapy plus their own stem cell transplant. It may help strengthen the transplant “conditioning” treatment before the transplant.
BernAges 18–75 - NCT07814508Recruiting
Continuous glucose monitor app study for insulin users
This study tests a new continuous glucose monitor (CGM) system with a predictive app to help people on insulin therapy manage their blood sugar better. It aims to see if the app improves daily life and glucose control.
Bad Mergentheim, Baden-WurttembergAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.