Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,236 recruiting studies in this area right now.
By phase
- Not applicable3,144
- Phase 21,066
- Phase 1823
- Phase 1/Phase 2446
- Phase 3426
- Phase 4238
- Phase 2/Phase 393
Top conditions
- Multiple Sclerosis345
- Multiple Myeloma334
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis141
- Type 1 Diabetes131
- Atopic Dermatitis129
- Systemic Lupus Erythematosus126
- Acute Lymphoblastic Leukemia123
- HIV Infections117
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 170
- Hodgkin Lymphoma67
- Leukemia64
- Rheumatoid Arthritis (RA)64
- Mantle Cell Lymphoma62
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)91
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris70
- Novartis Pharmaceuticals65
- M.D. Anderson Cancer Center63
- AstraZeneca57
- City of Hope Medical Center46
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California492
- Maryland196
- Alabama179
- Arizona141
- Florida141
- New York122
- Massachusetts120
- Texas119
- Illinois82
- Colorado77
Recruiting studies6,236 total
- NCT05389293RecruitingPhase 2
Mosunetuzumab with or without zanubrutinib for follicular lymphoma
This trial studies mosunetuzumab alone or combined with zanubrutinib to treat people with follicular lymphoma that is advanced or causing problems. It’s meant to see which approach works better and is safe for long-term treatment.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07146906RecruitingPhase 2
Study of zigakibart for IgA nephropathy
This trial tests a new drug called zigakibart for people with IgA nephropathy, a kidney disease. It aims to see if the drug can help reduce protein in the urine and protect kidney function.
Denver, ColoradoAges 18–100 - NCT06838949RecruitingPhase 2
Herombopag for ITP in patients age 60 and older
This trial tests a medication called Herombopag to raise platelet counts in adults aged 60 or older with immune thrombocytopenia (ITP). The goal is to see if it is safe and effective for this age group.
TianjinAges 60 years+ - NCT06798298Recruiting
Long-term safety study of gene modified T cell treatment
This study is a long-term safety check for people who have already received a gene modified T cell treatment in a previous study sponsored by 2seventy bio or Regeneron Pharmaceuticals. The goal is to monitor your health for years after that treatment to see how well it works and if any side effects appear over time.
Nashville, TennesseeAges 18 years+ - NCT06784336RecruitingPhase 2
Testing starch and a drug after stem cell transplant
This trial tests if adding a special starch and a drug called deferasirox can improve recovery for people who have a stem cell transplant for blood disorders. The starch may help with gut health and the drug reduces iron, which might help prevent complications.
Ann Arbor, MichiganAges 18 years+ - NCT06692543Recruiting
How longtime exercise habits affect aging muscles and metabolism
This study compares the health of older adults (over 55) who have been very active their entire adult lives with those who have been mostly inactive. The goal is to see how exercise affects muscle, nerves, and immune-metabolic health over time.
NiceAges 55 years+ - NCT06504225Recruiting
Long-term follow-up for EVEROLD study patients
This trial follows patients who completed the EVEROLD study to collect long-term health data. It is an observational study that does not test a new treatment.
AmiensAges 18 years+ - NCT06127563Recruiting
Better vaccine care for frail patients
This trial tests whether offering vaccines more carefully to frail patients in certain hospital departments improves their health. It is open to adults living in Lazio who are being treated in one of five specific departments.
Rome, LazioAges 18 years+ - NCT05477901Recruiting
Cash transfers study in mothers and children
This study checks whether receiving cash support (a government cash transfer program) helps children’s brain and development. Families will be assessed, and children must be able to take part in activities that may include an MRI scan.
New York, New YorkAges 23–45 - NCT01132859Recruiting
Study of how immune cells respond in adults
This study looks at how your body’s immune system reacts in different tissues by collecting and storing samples for research. You might be able to join if you’re an adult and can consent, and if you don’t have certain bleeding risks that could make sample collection unsafe.
Bethesda, MarylandAges 18–120 - NCT06486051RecruitingPhase 2
CAR T-cell therapy for adults with relapsed large B-cell lymphoma
This trial tests a new treatment called atlacabtagene autoleucel, which uses your own immune cells to fight the lymphoma. It's designed for people whose lymphoma has come back or not responded to initial treatments.
Auckland, AucklandAges 18–75 - NCT07751783Recruiting
Exercise program for cancer survivors
This trial helps people who have finished cancer treatment start a supervised exercise routine to improve their health. It tests whether a structured program with professional guidance is safe and helpful.
Kaohsiung, TaiwanAges 18–80 - NCT05632380RecruitingPhase 1/Phase 2
Stem cell transplant with CAR-T therapy for high-risk myeloma
This study combines a stem cell transplant with a special immune therapy (CAR-T) to treat multiple myeloma that is very aggressive and has not responded well to initial treatments. The goal is to see if this combination can better control the cancer.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07753603RecruitingPhase 3
Linsitinib for active moderate to severe thyroid eye disease
This study tests an experimental pill (linsitinib) for people with active thyroid eye disease. Participation may help reduce eye bulging and other symptoms, especially if other treatments haven't worked.
Las Vegas, NevadaAges 18 years+ - NCT05656378Recruiting
Storing samples to study how the body interacts with microbes
This study creates a storage bank of biological samples like blood, stool, and tissue. Researchers will use these samples to learn how the body interacts with the natural microbes that live in and on us, which may help improve treatments for many diseases.
Bethesda, MarylandAges Any age - NCT07168772Recruiting
Probiotic supplement for multiple sclerosis
This study tests whether adding a probiotic supplement to your usual MS treatment (or to no treatment) can help manage relapsing-remitting multiple sclerosis. It aims to see if the probiotic is safe and beneficial as an add-on therapy.
Barcelona, BarcelonaAges 18–60 - NCT05809284Recruiting
Understanding CAR T-cell therapy persistence in young patients with ALL
This study looks at why CAR T-cell therapy stops working in some children and young adults with leukemia. It aims to help doctors understand how to make this treatment last longer.
LondonAges Up to 25 years - NCT05405491Recruiting
DNA test to guide antibiotic use for pneumonia in ICU patients
This study tests whether using a DNA test on lung fluid can help doctors choose better antibiotics for pneumonia in ICU patients with weakened immune systems. It may lead to more effective treatment and fewer side effects.
LilleAges 18 years+ - NCT07145632Recruiting
Smartphone app to improve inhaler technique for asthma and copd
This study tests a smartphone app that helps you learn or improve how to use your inhaler correctly. The app provides education and training to make sure you get the most from your medication.
Uppsala, Uppsala CountyAges 16 years+ - NCT07661537RecruitingPhase 1
Study of SHR-3079 for B-cell Non-Hodgkin Lymphoma
This trial tests a new drug called SHR-3079 for people with B-cell non-Hodgkin lymphoma whose cancer did not get better or came back after at least one standard treatment. The goal is to see if the drug can help shrink tumors or slow the disease.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07686484RecruitingEarly Phase 1
Testing a new drug in healthy volunteers
This trial tests an experimental drug called HRS-3095 in healthy people to check its safety and how the body handles it. It may help find the right dose for future studies.
Bayswater, VictoriaAges 18–55 - NCT07393282RecruitingPhase 3
Comparing two treatments for high-risk smoldering multiple myeloma
This trial tests a new drug called linvoseltamab against an existing treatment, daratumumab, for people with a high-risk form of smoldering multiple myeloma. The goal is to see which one works better to delay or prevent the disease from becoming active multiple myeloma.
Atlanta, GeorgiaAges 18 years+ - NCT07629583RecruitingPhase 1
Testing cevostamab for lupus with kidney involvement
This study tests a new drug called cevostamab for people with systemic lupus erythematosus (SLE), a condition where the immune system attacks the body's own tissues. Some participants also have lupus nephritis, which means the disease is affecting their kidneys. The drug may help by targeting a specific part of the immune system.
SevilleAges 18–75 - NCT06864273Recruiting
Pharmacy training to help with hearing aids in rural areas
This study trains pharmacy technicians in rural Alabama and Mississippi to help adults with mild to moderate hearing loss use over-the-counter hearing aids. It aims to improve access to hearing care in communities where it is limited.
Tuscaloosa, AlabamaAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,236 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,675 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.