Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT07835724Recruiting
Understanding what causes type 1 diabetes
This study looks at how things in the environment might affect the risk of type 1 diabetes. It aims to find out what triggers the disease, which could help with prevention and treatment.
Changsha, HunanAges 3–70 - NCT07834853Recruiting
HIV prevention and care study for Latino men and transgender women
This study helps Latino men, transgender women, and nonbinary people in Washington, DC and the San Francisco Bay Area get HIV prevention or care services. It aims to connect you with health services and support, whether you are living with HIV or want to prevent it.
Berkeley, CaliforniaAges 18 years+ - NCT07835607Recruiting
Comparing pet scans and mri for thyroid eye disease
This study compares two PET imaging methods and an MRI to see which better shows inflammation in thyroid eye disease. Participation may help improve detection and monitoring of this condition.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07838714RecruitingPhase 1
Cord blood CAR-T cells for relapsed B-cell leukemia
This trial tests a new type of personalized cell therapy using your own immune cells (called CAR-T cells) that are designed to find and attack leukemia cells that have certain markers (CD19 and CD22). It is for people whose leukemia has returned or not responded to standard treatments.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06462768Recruiting
Study of immune cell activity in systemic sclerosis
This study looks at a specific type of immune cell activity (called neutrophil extracellular traps) in the blood of people with systemic sclerosis, other connective tissue diseases, and healthy volunteers. It aims to understand how these cells may be involved in the disease and could lead to better treatments.
ReimsAges 18 years+ - NCT06469593Recruiting
Automated insulin delivery for type 1 diabetes study
This study tests a new automated insulin delivery (AID) system that connects your insulin pump to your glucose monitor to help keep your blood sugar in range. It is for both children and adults with type 1 diabetes who have not used an AID system before.
Herlev, Greater CopenhagenAges 7 years+ - NCT07828106Recruiting
Remote diabetes monitoring for type 1 diabetes in children and youth
This study tests a remote diabetes monitoring system that uses WhatsApp to help improve blood sugar control and quality of life in children and young people with type 1 diabetes. It is for those already using a Dexcom CGM and a closed-loop insulin pump.
Ramat GanAges 1–25 - NCT07831798RecruitingPhase 1/Phase 2
Gene therapy for type 1 diabetes
This study tests a new gene therapy (VV-14300) that aims to help people with type 1 diabetes make insulin again. It might improve blood sugar control and reduce the need for insulin.
TorontoAges 18–65 - NCT07829614RecruitingPhase 1
F182112 study for people with lupus
This study tests a new drug called F182112 for people with systemic lupus erythematosus (SLE), a condition where the immune system attacks the body. The drug targets certain immune cells to possibly reduce lupus symptoms.
ShanghaiAges 18–65 - NCT07829302RecruitingPhase 1/Phase 2
Gene therapy for type 1 diabetes
This trial tests an investigational gene therapy that may help people with type 1 diabetes produce some insulin on their own, potentially reducing the amount of insulin they need. It is an early-stage study, so participants will be closely monitored for safety and any changes in their diabetes control.
MelbourneAges 18–65 - NCT07826689RecruitingPhase 1/Phase 2
Oral pill for relapsing multiple sclerosis
This study tests an experimental oral drug, PRO-1562, in two parts: first in healthy volunteers to check safety, then in people with relapsing multiple sclerosis to see if it can reduce disease activity. It may offer a new, convenient treatment option.
Adelaide, South AustraliaAges 18–65 - NCT07827586Recruiting
Ocrelizumab injection for relapsing-remitting multiple sclerosis
This study looks at how well the injected form of ocrelizumab works for people with relapsing-remitting multiple sclerosis (RRMS) in everyday care. It aims to understand the treatment's effects and side effects outside of a clinical trial setting.
LjubljanaAges 18 years+ - NCT07826767RecruitingPhase 1/Phase 2
Gene therapy for inherited immune disease
This trial tests a new gene therapy (SGX-001) for chronic granulomatous disease caused by a specific genetic change. The treatment tries to fix the gene in your immune cells so they can fight infections better, and the trial will follow participants for up to 15 years to make sure it's safe and effective.
UlmAges 1.5 years+ - NCT06463717Recruiting
Stem cell transplant timing for multiple myeloma with no cancer cells left
This trial looks at people with newly diagnosed multiple myeloma who have no detectable cancer cells after initial treatment. It aims to see if these patients can do well without a stem cell transplant or with a delayed one, reducing unnecessary side effects.
Hangzhou, ZhejiangAges 18–70 - NCT06390878Recruiting
Study on natural kindergarten yards
This study looks at how bringing nature back into kindergarten yards might affect children's health. It involves children who attend kindergarten and have not used antibiotics recently.
Helsinki, UusimaaAges 1–5 - NCT07828080Recruiting
Hip replacement using a newer stem design
This study looks at how well a newer type of hip replacement stem (called the Actis stem) works for people having their first hip replacement. It aims to see if this stem provides good outcomes for various hip conditions.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT07830082Recruiting
Drawing and writing activities for teens with type 1 diabetes
This study tests whether drawing and writing activities can help teenagers with type 1 diabetes manage their condition. It may improve their emotional well-being and diabetes control.
Ankara, AnkaraAges 9–18 - NCT07832643Recruiting
Allergy and breathing problems in babies at 12 months
This study follows full-term babies from birth to 12 months to see if allergies affect breathing problems. It may help doctors understand and prevent respiratory issues in infants.
Amiens, PicardieAges Up to 1 year - NCT07833020Recruiting
Gyrotonic exercise for teens with lupus after intensive care
This study tests whether a special exercise program called Gyrotonic can help teenagers with childhood lupus recover after a stay in the intensive care unit (ICU). The exercises aim to improve strength and movement, which may be affected after such a serious illness.
Dokki, Giza GovernorateAges 13–17 - NCT07827716RecruitingPhase 2
Testing terfenadine for relapsing multiple sclerosis
This study tests whether terfenadine, an allergy medicine, is safe and helpful for people with relapsing-remitting multiple sclerosis (MS). It may reduce MS activity and improve outcomes.
Wuhan, HubeiAges 18–65 - NCT07833696Recruiting
Study of severe hives that don't respond to omalizumab
This study looks at people with severe hives (chronic urticaria) that have not improved with the usual dose of the medicine omalizumab. It aims to better understand these cases and how they are managed, which may help improve future care.
Besançon, Franche-comtéAges 18–80 - NCT07828626Recruiting
Retained insulin benefits for good health
This study looks at whether keeping some natural insulin production helps people with diabetes stay healthier. It may help researchers understand the benefits of having some of your own insulin.
Truro, CornwallAges 18 years+ - NCT06085118Recruiting
Observatory on cow's milk protein allergy in babies
This study is watching babies with a cow's milk protein allergy who are given a special formula called Pepticate® Syneo®. It helps doctors learn how babies do on this formula over time.
NiceAges Up to 8 months - NCT03882840RecruitingPhase 1/Phase 2
T-like NK cell therapy for cancers with low MHC-I
This early-stage trial tests a lab-made immune cell treatment (T-like NK cells) for advanced cancers that have low or missing MHC-I on their cells. Because the treatment aims to “re-activate” the immune system against these cancers, you may be eligible if your cancer matches this feature and you meet safety requirements.
Guangzhou, GuangdongAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.