Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,146
- Phase 21,063
- Phase 1820
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis140
- Type 1 Diabetes134
- Atopic Dermatitis130
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections113
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland195
- Alabama176
- Florida145
- Arizona141
- New York122
- Massachusetts119
- Texas118
- Illinois81
- Colorado76
Recruiting studies6,230 total
- NCT06334341Enrolling by invitation
Study to improve PrEP use in primary care
This trial tests ways to help primary care providers and their patients start using PrEP, a daily pill that prevents HIV. It may be right for you if you are interested in HIV prevention.
Detroit, MichiganAges 18 years+ - NCT06314048Enrolling by invitation
Diabetes Support Program for Kids with Type 1
This study tests a program that helps kids and teens with type 1 diabetes use a continuous glucose monitor (CGM) and get remote check-ins from their care team. It aims to make diabetes management easier and more connected.
Palo Alto, CaliforniaAges 6 months–21 years - NCT06300047Enrolling by invitation
Diabetes transition support for young adults
This study tests a transition coordinator to help teens with type 1 diabetes move from pediatric to adult care. It aims to make the process smoother and improve health outcomes.
Calgary, AlbertaAges 17–18 - NCT06262399Enrolling by invitation
Long-term safety check for NTLA-2002 recipients
This study follows people who previously got the experimental drug NTLA-2002 in an Intellia trial. It checks long-term safety and health effects, even if you already stopped treatment.
Campbelltown, New South WalesAges Any age - NCT06261528Enrolling by invitationPhase 1
Light therapy for sleepiness in progressive MS
This trial tests whether a special light therapy can help people with progressive multiple sclerosis who feel sleepy during the day. It aims to improve energy, mood, and sleep patterns.
Dallas, TexasAges 18 years+ - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT06223074Enrolling by invitationPhase 2
Nasal Steroid Spray for MS Relapses
This study tests a nasal spray form of the steroid methylprednisolone for treating MS relapses. The goal is to see if this new way of taking the medicine works as well or better than standard treatments.
Mexico CityAges 18–65 - NCT06211413Enrolling by invitation
Tracking heart issues in CLL patients on BTK inhibitors
This study watches for high blood pressure and irregular heartbeats in people with CLL who are starting a type of targeted therapy called a BTK inhibitor (acalabrutinib or zanubrutinib). Researchers will use a smartwatch and blood pressure cuff to monitor your heart health at home.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06183723Enrolling by invitation
Study to improve HIV care for those struggling with medications
This study tests a program to help people living with HIV who have difficulty taking their medications consistently. The goal is to see if extra support can improve health outcomes.
Kaohsiung CityAges 18 years+ - NCT06167642Enrolling by invitation
Retinal health and nerve markers in MS patients taking ofatumumab
This study looks at how ofatumumab (Kesimpta) affects the back of the eye (retina) and certain nerve proteins in the blood in people with relapsing multiple sclerosis. It may help doctors understand how well the medication is protecting the eyes and nerves.
Baltimore, MarylandAges 18–70 - NCT06163508Enrolling by invitation
Long-term follow-up for Q-Cells recipients
This study is for people who have already received Q-Cells treatment. It does not test new treatments; instead, it checks on your health over a long time to see how you are doing.
Dallas, TexasAges Any age - NCT06158490Enrolling by invitationPhase 2
JYP0061 tablet for moderate to severe eczema
This trial tests a new tablet called JYP0061 for people with moderate to severe atopic dermatitis (eczema) that has lasted at least a year. It aims to see if the drug is safe and effective in reducing symptoms.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06154135Enrolling by invitation
Test of DBLG1 closed-loop insulin delivery for type 1 diabetes
This study tests how well a new closed-loop insulin delivery system (DBLG1) helps manage blood sugar and improves quality of life for adults with type 1 diabetes. If you are starting this system, the study will track your glucose control and ask about your daily experiences.
AalstAges 18 years+ - NCT06147453Enrolling by invitation
Oscillating positive expiratory pressure therapy for mucus in asthma
This trial tests a device that uses vibrations to help clear mucus from your lungs. It may improve airflow and mucus buildup in people with moderate to severe asthma.
Hamilton, OntarioAges 18 years+ - NCT06144229Enrolling by invitation
HPV Vaccine in Women with HIV
This study looks at how well the HPV vaccine works in women living with HIV and whether it helps make cervical cancer screening more accurate. If you are a woman with HIV between 21 and 40 years old and already part of certain other HIV studies, you may be able to join.
Denver, ColoradoAges 21–40 - NCT06113588Enrolling by invitation
Moving from pediatric to adult diabetes care
This trial looks at how teenagers and young adults with type 1 diabetes move from pediatric to adult diabetes care. The goal is to learn how to make this transition smoother and better support patients and their families.
Sydney, New South WalesAges 16 years+ - NCT06001138Enrolling by invitation
FutureMS-2: A Follow-Up Study for MS
This study follows up with people who have Multiple Sclerosis and were in the earlier FutureMS study. It uses MRI scans to learn more about MS and find better ways to treat it.
AberdeenAges 18 years+ - NCT05998291Enrolling by invitation
Dermatitis herpetiformis not helped by gluten-free diet
This trial studies two groups of people with dermatitis herpetiformis. One group has a rash that still appears even after following a strict gluten-free diet for at least 3 years. The other group responds well to the diet. The study will compare them to learn more and find better ways to help.
TampereAges 18 years+ - NCT05983874Enrolling by invitationPhase 1
Booster HIV vaccine study for those who got the first shots
This study tests two booster doses of an HIV vaccine to see if they are safe and boost the immune system. It is for healthy adults who already received three earlier doses of a related vaccine.
AmsterdamAges 18–51 - NCT05952999Enrolling by invitation
Studying Hospital-At-Home care done from home
This trial looks at how well a “Hospital at Home” program works when people start from the emergency department or are already in the hospital and can be cared for at home. It may help teams improve care at home for certain medical conditions and situations.
Peoria, IllinoisAges 18 years+ - NCT05947539Enrolling by invitation
Helping Ugandan young women stay engaged in HIV care
This study tests a couples-focused program to help HIV-positive adolescent girls and young women stay connected to HIV clinic visits and medicines. It may help if you’re currently not well engaged in HIV care or you’ve faced partner violence or controlling behavior.
KampalaAges 15 years+ - NCT05941559Enrolling by invitation
EMDR therapy for long-term rheumatoid arthritis pain
This trial tests whether eye-movement therapy (EMDR) can reduce long-lasting pain in people with rheumatoid arthritis (RA). You may be eligible if your RA has been relatively stable, your pain is still high, and you can take part in therapy sessions safely.
Enschede, OverijsselAges 18 years+ - NCT05923216Enrolling by invitation
Testing oral sesame treatment to reduce severe reactions
This study tests an oral (mouth) sesame treatment designed to help the body stay “unresponsive” to sesame after treatment. If you previously took part in the earlier sesame study, this trial may help you see whether a sustained tolerance can be achieved and maintained.
WarsawAges 4–17 - NCT05889806Enrolling by invitation
Study uses blood and tissue samples for gene and protein testing
This study collects and analyzes your donated samples (like blood or other biospecimens) to look for patterns in genes and proteins. The results may help researchers understand disease biology and improve future tests or treatments.
New Orleans, LouisianaAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,786 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.