Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,146
- Phase 21,063
- Phase 1820
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis140
- Type 1 Diabetes134
- Atopic Dermatitis130
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections113
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland195
- Alabama176
- Florida145
- Arizona141
- New York122
- Massachusetts119
- Texas118
- Illinois81
- Colorado76
Recruiting studies6,230 total
- NCT06609239Enrolling by invitationPhase 2
Long-term safety study of Lunsekimig for asthma
This trial tests the long-term safety and effectiveness of Lunsekimig, an investigational drug, for adults with asthma. It is for people who have already completed a previous Lunsekimig study and are on stable asthma medications.
Chandler, ArizonaAges 18 years+ - NCT06605612Enrolling by invitation
Falls risk test for people with muscle and nerve conditions
This study is creating a test to predict falls in people with neuromuscular disorders. You will fill out a questionnaire about your fall risk.
München, BavariaAges 18–65 - NCT06604663Enrolling by invitation
Using data to improve HIV care in Kenya
This trial is looking at how to improve HIV care by using data and interviews to help clinics make better decisions. It doesn't require you to do anything different—your regular clinic data will be used to see how well appointments are kept.
EldoretAges 18–100 - NCT06603935Enrolling by invitation
Digital medicine for allergic rhinitis management
This trial tests a digital platform to help manage allergic rhinitis (nasal allergies) and sinusitis. It's for adults whose symptoms are not well controlled despite treatment.
West Palm Beach, FloridaAges 18–65 - NCT06598345Enrolling by invitation
Pet fish care for better diabetes management in teens
This study tests if taking care of a pet fish can help kids aged 10-13 with type 1 diabetes improve their blood sugar control and take more responsibility for their diabetes care.
Durham, North CarolinaAges 10–13 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06560879Enrolling by invitationPhase 2
Probiotics to prevent stomach problems in children with leukemia
This trial tests whether probiotics can help prevent stomach and gut side effects from chemotherapy in children with leukemia. If your child is between 6 and 17, in the right phase of treatment, and doesn't have any major gut issues, they may be eligible.
Mexico City, CoyoacanAges 6–17 - NCT06559176Enrolling by invitationPhase 1/Phase 2
Gene editing trial for chronic granulomatous disease
This trial tests a new gene editing treatment called PM359 for people with a specific type of chronic granulomatous disease (CGD) caused by a delGT mutation in the NCF1 gene. The goal is to see if it's safe and helps fight infections and inflammation.
Los Angeles, CaliforniaAges 6 years+ - NCT06544798Enrolling by invitationPhase 2
Long-term follow-up of gene therapy for dry mouth
This study follows patients who previously received gene therapy for dry mouth caused by radiation. It aims to track long-term safety and any lasting benefits.
Gilbert, ArizonaAges 18 years+ - NCT06540027Enrolling by invitation
Minimally invasive surgery for rectal cancer inflammation
This study looks at how different types of surgery (open, laparoscopic, or robotic) affect inflammation throughout the body in people with rectal cancer. It may help doctors understand which approach is gentler on your immune system.
IstanbulAges Any age - NCT06526507Enrolling by invitationPhase 4
PrEP study for pregnant women in Kenya
This study aims to expand access to PrEP (a daily pill that prevents HIV) for pregnant and postpartum women visiting maternal and child health clinics in Kenya. It also includes health care workers who provide PrEP services.
Kapsabet, NandiAges 15–50 - NCT06518668Enrolling by invitationPhase 1
NKX019 cell therapy for lupus
This study tests a new therapy called NKX019, which uses specially engineered natural killer cells to target a protein on lupus cells. It is for people with moderate to severe lupus that has not responded to standard treatments, especially those with active kidney inflammation.
New York, New YorkAges 18–65 - NCT06500039Enrolling by invitation
Positive Psychology Exercises for People With MS
This study looks at whether positive psychology exercises (activities that boost well-being) can help people with multiple sclerosis. You will use a smartphone app to complete short exercises over several weeks.
BoluAges 18–65 - NCT06495593Enrolling by invitationPhase 4
Ocrelizumab's effect on immune cells in lymph nodes in MS
This study tests how ocrelizumab, a medication for MS, affects immune cells in your lymph nodes. It may help doctors understand how the drug works and why it helps some people more than others.
San Francisco, CaliforniaAges 18–65 - NCT06488846Enrolling by invitation
Giving HIV injections at home with a helper
This study tests whether having a trained friend or family member give you your HIV injections at home is safe and works as well as getting them at a clinic. You may qualify if you are already on the injectable HIV medication cabotegravir/rilpivirine (Cabenuva) and have a support person willing to help.
San Francisco, CaliforniaAges 18 years+ - NCT06487962Enrolling by invitation
Study on continuous glucose monitors for low-income adults with type 1 diabetes
This trial tests a program to help low-income adults with type 1 diabetes use continuous glucose monitors (CGM). You and a family member or friend will attend four weekly sessions to learn how to get the most out of the device.
Middletown, ConnecticutAges 18 years+ - NCT06472830Enrolling by invitation
MGUS and multiple myeloma awareness screening study
This study screens adults aged 40 and older for early signs of MGUS (a benign blood condition) and multiple myeloma (a blood cancer). You'll fill out questionnaires about your health to help with early detection.
Rochester, MinnesotaAges 40 years+ - NCT06464133Enrolling by invitation
Filaggrin gene study in Latinx patients with eczema
This study looks for gene changes (filaggrin mutations) in Latinx/Hispanic patients with atopic dermatitis (eczema) to better understand how these genes affect the condition. It involves a simple skin test or saliva sample.
Philadelphia, PennsylvaniaAges Any age - NCT06460077Enrolling by invitation
Studying MS brain lesions with iron rims using advanced scans
This study uses advanced MRI and PET scans to look at certain types of MS brain lesions called 'slowly expanding lesions' that have an iron rim. The goal is to better understand how these lesions behave over time, which may help guide future treatments.
Turku, Southwest FinlandAges 18–80 - NCT06421402Enrolling by invitation
Health program for chronic lung disease in Barcelona
This study tests a health program for people with serious lung conditions like COPD or hard-to-treat asthma, especially those who also have other health issues. It aims to see if the program helps them feel better and manage their health in Barcelona.
BarcelonaAges Up to 85 years - NCT06420661Enrolling by invitation
School program for children with type 1 diabetes
This study tests a special program called SPACE that helps children with type 1 diabetes by working together with their school nurse and diabetes team. The goal is to improve diabetes care and support at school.
Pittsburgh, PennsylvaniaAges 5–12 - NCT06415110Enrolling by invitation
Comparing bone grafts for lower back fusion surgery
This study tests if a special bone graft material (Allosync Expand) plus your own bone is as good as using just your own bone for spinal fusion surgery. It might help people with back or leg pain caused by a slipped vertebra and narrowed spine.
Southfield, MichiganAges 22 years+ - NCT06375993Enrolling by invitationPhase 1
Prula-cel for autoimmune diseases: a phase 1 study
This trial tests a new treatment called prulacabtagene leucel (prula-cel), which is a type of immune cell therapy (CAR T-cells) for people with certain autoimmune diseases. It aims to see if it can reset the immune system and reduce disease activity in conditions like lupus, scleroderma, vasculitis, or myositis.
Redwood City, CaliforniaAges 18–80 - NCT06350682Enrolling by invitation
HIV prevention app study for young men
This study tests a smartphone program to help young men who have sex with men stay healthy and prevent HIV. It's designed for people already getting care at certain clinics.
Abuja, NigeriaAges 15–24
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,786 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.