Treatment
Dexmedetomidine clinical trials
We’re tracking 188 recruiting studies that include Dexmedetomidine, each written for real people, not researchers, below.
Recruiting studies
- NCT07144007Recruiting
Preventing agitation after rhinoplasty with propofol and dexmedetomidine
This study tests whether giving two medicines, propofol and dexmedetomidine, during rhinoplasty can help prevent confusion or restlessness when waking up from anesthesia. It may be a good option if you are having nose surgery and are generally healthy.
Van, TuşbaAges 18–65 - NCT07168720RecruitingPhase 2
Dexmedetomidine patch for calming children before surgery
This study tests a skin patch that helps children relax before surgery. The patch contains a medicine that is absorbed through the skin to reduce anxiety, so the child may need less anesthesia.
Guangzhou, GuangdongAges 2–6 - NCT07180940RecruitingPhase 4
Comparing two medicines added to a nerve block for back surgery
This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.
PoznanAges 18 years+ - NCT07239479Recruiting
Dexmedetomidine and desflurane for laparoscopic colon surgery
This study tests a combination of two drugs (dexmedetomidine and desflurane) used during keyhole colon surgery to see if it helps with recovery. It is designed for generally healthy adults having a planned laparoscopic colectomy.
Ho Chi Minh City, Ho Chi MinhAges 18–65 - NCT07285083Recruiting
Pain relief after abdominal surgery: comparing two numbing medicines
This study compares two numbing medicines (bupivacaine alone vs. bupivacaine plus dexmedetomidine) to see which provides better pain relief after abdominal surgery. If you are having a planned abdominal operation, this trial may help improve your recovery comfort.
Rahim Yar Khan, Punjab ProvinceAges 21–45 - NCT07290595RecruitingPhase 2/Phase 3
Comparing two medicines for faster nerve block in arm surgery
This study compares two medicines (dexmedetomidine and dexamethasone) added to a numbing drug (ropivacaine) for a nerve block in the collarbone area. The goal is to see which combination works faster and better for pain relief during upper limb surgery.
Sāhīwāl, Punjab ProvinceAges 18–70 - NCT07324057Recruiting
Medication before surgery to reduce autism-related anxiety in children
This trial tests whether a nose spray given before anesthesia can help children with autism feel calmer and have fewer behavior problems after surgery. It compares two medications, dexmedetomidine and esketamine, to see if they reduce negative post-surgery changes.
Nanjing, JiangsuAges 2–12 - NCT07327372Recruiting
Numbing with sedation for hip surgery in older adults
This trial tests a numbing injection (called a PENG block) plus a sedative (dexmedetomidine) for older adults having hip surgery. The goal is to see if this combination gives better pain relief and fewer side effects.
PoznanAges 65–100 - NCT07340008Recruiting
Comparing medicines for calm stitch removal in children after cleft surgery
This study compares three different medicines (ketamine, nalbuphine, and dexmedetomidine) to help keep children calm and comfortable while their stitches are removed after cleft surgery. It may help find the best way to reduce pain and anxiety in young children during this procedure.
LjubljanaAges 6 months–3 years - NCT07350928RecruitingPhase 3
Nasal spray before breast-saving surgery for calm wakefulness
This trial tests a nasal spray (dexmedetomidine) given before breast-conserving surgery to help you stay calm and comfortable while awake during the procedure. It aims to improve your recovery and waking experience after surgery.
TianjinAges 20–70 - NCT07368062Recruiting
Mental health after a heart rhythm drug in the ICU
This study looks at the long-term mental health of people who received a drug called dexmedetomidine during an electrical storm (a dangerous heart rhythm) in the ICU.
Ottawa, OntarioAges Any age - NCT07386600Recruiting
Comparing two drugs for knee replacement pain relief
This trial tests two different drugs (dexamethasone and dexmedetomidine) added to a standard nerve block for knee replacement. It aims to see which one provides better pain control after surgery.
PoznanAges 65–100 - NCT05851768Recruiting
Easing thoracotomy pain with two different drugs
This trial compares two drugs added to a standard numbing medicine to see which works better for pain relief after chest surgery (thoracotomy). It may help find a way to reduce pain more effectively.
CairoAges 18–65 - NCT07427446RecruitingPhase 4
Calming drugs for children after heart catheterization
This trial compares two combinations of sedative medicines (dexmedetomidine with midazolam versus ketamine with midazolam) to see which better prevents confusion or agitation when a child wakes up after a heart catheterization procedure. It may help your child recover more calmly.
CairoAges 2–6 - NCT07462195RecruitingPhase 4
Dexmedetomidine for smoother recovery after thyroid surgery
This trial tests whether adding a medicine called dexmedetomidine during thyroid surgery helps you wake up more calmly and comfortably. It may reduce side effects like confusion or shakiness after anesthesia.
HanoiAges 18–65 - NCT07523438Recruiting
Nasal Medication to Reduce Agitation After Eye Surgery in Young Children
This study tests whether a medication given through the nose (dexmedetomidine) can help children stay calmer when waking up from eye-muscle surgery. Some children get very agitated or upset when coming out of anesthesia, and this medication might help prevent that.
AlexandriaAges 3–6 - NCT07565116Recruiting
Numbing Nose Spray vs. Calming Liquid Before Pediatric Surgery
This trial compares two safe, common ways to help children relax before surgery: a medicine sprayed in the nose versus a medicine given by mouth. The goal is to see which one works better and is easier for kids.
Diyarbakır, Outside of the USAges 2–10 - NCT07669012RecruitingPhase 1
Sedation comparison for child heart hole repair
This study compares two sedation combinations (ketamine-propofol vs. dexmedetomidine-propofol) in children having a heart catheter procedure to close a simple hole or opening. The goal is to see which combination provides safer, more comfortable sedation.
CairoAges 2–12 - NCT07125573Enrolling by invitation
Esketamine and dexmedetomidine for recovery after lung surgery
This trial tests if adding two medicines (esketamine and dexmedetomidine) during your thoracoscopic (keyhole) lung surgery helps you recover better and feel less discomfort afterward.
Kunming, YunnanAges 18–65 - NCT07034898Enrolling by invitationPhase 4
Dexmedetomidine vs Labetalol for Airway Stress in Brain Surgery
This trial compares two medicines (dexmedetomidine and labetalol) to see which one better controls stress on the airway during brain surgery in people with high blood pressure. The goal is to find a safer way to manage your heart rate and blood pressure while you are under anesthesia.
CairoAges 30–60 - NCT07023991Enrolling by invitationPhase 1
Dexmedetomidine with bupivacaine for children's lower abdominal surgery
This trial tests whether adding dexmedetomidine (a sedative) to bupivacaine (a numbing medicine) improves pain relief from a nerve block in young children having lower belly surgery. The goal is to see if the combination provides better or longer-lasting pain control.
Cairo, EgyptAges 1–7 - NCT06849466Enrolling by invitationPhase 4
Perioperative dexmedetomidine for chronic pain after lung surgery
This study tests whether giving the medication dexmedetomidine during and after surgery can prevent long-term pain after a thoracoscopic lung resection. If you are scheduled for this type of lung surgery, you may be able to join and help see if this drug makes recovery less painful over time.
Beijing, Beijing MunicipalityAges 18–80 - NCT06148311Enrolling by invitationPhase 2
Dexmedetomidine film for autonomic crises in Familial Dysautonomia
This study tests a new dissolvable film containing dexmedetomidine (a medicine that calms overactive stress responses) for people with Familial Dysautonomia who experience sudden episodes called autonomic crises. It aims to treat these crises at home without needing a hospital visit.
New York, New YorkAges 16–80 - NCT05705128Enrolling by invitationPhase 2/Phase 3
Dexmedetomidine to help pain after shoulder surgery
This trial studies whether dexmedetomidine can reduce pain after elective shoulder arthroscopy surgery done under general anesthesia. If you’re eligible, it may help improve postoperative comfort and reduce the need for additional pain treatment.
AsyutAges 18–60
Common questions
- Are there clinical trials studying Dexmedetomidine?
- Yes. Clin2 currently lists 188 recruiting studies that include Dexmedetomidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dexmedetomidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dexmedetomidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dexmedetomidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.