Treatment
Dexmedetomidine clinical trials
We’re tracking 194 recruiting studies that include Dexmedetomidine, each written for real people, not researchers, below.
Recruiting studies
- NCT07034898Enrolling by invitationPhase 4
Dexmedetomidine vs Labetalol for Airway Stress in Brain Surgery
This trial compares two medicines (dexmedetomidine and labetalol) to see which one better controls stress on the airway during brain surgery in people with high blood pressure. The goal is to find a safer way to manage your heart rate and blood pressure while you are under anesthesia.
CairoAges 30–60 - NCT07023991Enrolling by invitationPhase 1
Dexmedetomidine with bupivacaine for children's lower abdominal surgery
This trial tests whether adding dexmedetomidine (a sedative) to bupivacaine (a numbing medicine) improves pain relief from a nerve block in young children having lower belly surgery. The goal is to see if the combination provides better or longer-lasting pain control.
Cairo, EgyptAges 1–7 - NCT06849466Enrolling by invitationPhase 4
Perioperative dexmedetomidine for chronic pain after lung surgery
This study tests whether giving the medication dexmedetomidine during and after surgery can prevent long-term pain after a thoracoscopic lung resection. If you are scheduled for this type of lung surgery, you may be able to join and help see if this drug makes recovery less painful over time.
Beijing, Beijing MunicipalityAges 18–80 - NCT06148311Enrolling by invitationPhase 2
Dexmedetomidine film for autonomic crises in Familial Dysautonomia
This study tests a new dissolvable film containing dexmedetomidine (a medicine that calms overactive stress responses) for people with Familial Dysautonomia who experience sudden episodes called autonomic crises. It aims to treat these crises at home without needing a hospital visit.
New York, New YorkAges 16–80 - NCT05705128Enrolling by invitationPhase 2/Phase 3
Dexmedetomidine to help pain after shoulder surgery
This trial studies whether dexmedetomidine can reduce pain after elective shoulder arthroscopy surgery done under general anesthesia. If you’re eligible, it may help improve postoperative comfort and reduce the need for additional pain treatment.
AsyutAges 18–60 - NCT07392177RecruitingPhase 2
Understanding the brain's role in insomnia
This trial tests whether a part of the brain called the locus coeruleus is involved in insomnia. It involves sleep questionnaires and possibly brain imaging to understand your sleep problems better.
Macquarie Park, New South WalesAges 30–65 - NCT07465185RecruitingPhase 2
Testing a drug for cesarean delivery pain relief
This study compares a standard spinal anesthetic (bupivacaine) with or without an added drug (dexmedetomidine) to see which works better for pain relief during planned cesarean delivery. It may help find a safer or more effective option for mothers.
Banhā, Elqalyoubea,Ages 20–35 - NCT03593408Recruiting
Study drug levels in children on ECMO
This study measures how sedating and pain medicines move through the body in children who are supported by ECMO (a heart-lung machine). It may help doctors choose safer and more effective dosing for sedation and pain control during ECMO.
Boston, MassachusettsAges birth–17 years - NCT06823349RecruitingPhase 4
Pain relief study for normal labor
This trial compares a single injection of pain medicine into the spinal fluid to other methods during normal labor. It aims to see how well it works for women in active labor with a single, full-term baby in head-down position.
AswānAges Any age - NCT04669457Enrolling by invitationPhase 4
Study of delirium risk in young children having ear surgery
This trial looks at confusion or “delirium” after anesthesia in babies and young children having a myringotomy (ear procedure). It may help doctors understand which children are more likely to experience delirium and how to reduce that risk.
Worcester, MassachusettsAges 3 months–9 years - NCT03426579Recruiting
Testing sedation monitoring during anesthesia for children’s throat surgery
This trial looks at whether a monitoring method for how deeply a child is sedated matches how the child’s reflexes react during intravenous anesthesia. It may help anesthesiologists keep children safer and more comfortable during direct laryngoscopy procedures using medications like dexmedetomidine and remifentanil.
Edegem, AntwerpAges 1 month–8 years - NCT05383495RecruitingPhase 3
Calming medicine during child laceration repair
This trial tests a calming/anxiety-reducing medicine to see if it helps children feel less scared during stitches for a skin cut. It may help make the repair process easier for children and their caregivers.
London, OntarioAges 2–12 - NCT07184801RecruitingPhase 3
Comparing two sedatives for medical thoracoscopy
This trial tests if dexmedetomidate or midazolam is safer and works better for sedation during a medical thoracoscopy, a procedure to look inside the chest. It may help you if you need this procedure for an unclear pleural effusion.
Chandigarh, ChandigarhAges 12–90 - NCT07389096RecruitingPhase 4
Pain relief without opioids for teens having spine surgery
This trial tests if a drug combination that avoids opioids can safely control pain during and after scoliosis surgery in teenagers. It aims to reduce opioid side effects and improve recovery.
Port SaidAges 8–18 - NCT07105618Recruiting
IV-only anesthesia for brain tumor surgery
This study tests a type of anesthesia given only through an IV (total intravenous anesthesia) for people having brain tumor surgery. It looks at how well it works and how safe it is compared to other methods.
ZagazigAges 21–60 - NCT06575530RecruitingPhase 4
Remimazolam for sedation after non-cardiac surgery
This trial tests a sedative called remimazolam besylate in patients who need a breathing tube and light sedation after non-cardiac surgery. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges 18–64 - NCT06427707RecruitingPhase 2/Phase 3
Adding propofol or ketamine to magnesium and lidocaine for nasal surgery
This trial tests whether adding propofol or ketamine to a standard combination of magnesium and lidocaine improves pain control and recovery for people having nasal surgery. It aims to find a better way to manage anesthesia and reduce side effects.
Cairo, Cairo GovernorateAges 18–60 - NCT07221539Recruiting
Waking the brain with ultrasound during sedation
This study uses focused ultrasound to stimulate a deep brain region and see if it can help people wake up faster from anesthesia. Healthy volunteers will be sedated and monitored while the ultrasound is applied.
Ann Arbor, MichiganAges 18–40 - NCT07564531Recruiting
Safe sedation for heart catheterization in children
This study tests whether a combination of two sedative medications (dexmedetomidine and ketamine) works safely and effectively to keep children calm and still during heart catheterization—a procedure where a thin tube is guided through blood vessels to the heart for diagnosis or treatment.
HanoiAges Up to 18 years - NCT07231926Recruiting
Spinal morphine for recovery after keyhole lung surgery
This trial tests whether giving a small dose of morphine into the fluid around the spinal cord (intrathecal) can improve pain relief and recovery after keyhole lung surgery. It aims to help patients feel better faster and have fewer complications.
ErzurumAges 18–70 - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Daytona Beach, FloridaAges Any age - NCT05681572RecruitingPhase 3
Sedation before surgery to help kids feel better after anesthesia
This study tests whether giving a calming medicine before general anesthesia improves how children feel and experience anesthesia afterward. The goal is to see which pre-surgery approach works best and is comfortable for kids.
Montpellier, MontpellierAges 7–18 - NCT03343873Recruiting
Comparing anesthetics and brain connectivity on MRI
This study tests how different anesthesia medicines affect how brain areas communicate with each other, measured during an MRI scan. It may help researchers understand how anesthesia can change brain networks in both healthy people and people with brain tumors.
BeijingAges 18–65 - NCT03756961Recruiting
Opioid-free care plan for people having weight-loss surgery
This trial studies whether an opioid-free or opioid-sparing care pathway can improve comfort and outcomes for adults undergoing laparoscopic weight-loss surgery. It may help people avoid side effects from opioid pain medicines while still managing pain safely.
Lindesberg, Region ÖrebroAges 18 years+
Common questions
- Are there clinical trials studying Dexmedetomidine?
- Yes. Clin2 currently lists 194 recruiting studies that include Dexmedetomidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dexmedetomidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dexmedetomidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dexmedetomidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.