Treatment
Dexmedetomidine clinical trials
We’re tracking 178 recruiting studies that include Dexmedetomidine, each written for real people, not researchers, below.
Recruiting studies
- NCT07698665Recruiting
Ketamine vs dexmedetomidine in scalp block for brain tumor surgery
This trial compares two medicines, ketamine and dexmedetomidine, added to a scalp nerve block during brain tumor removal surgery. The goal is to see which provides better pain control and recovery after surgery.
Cairo, GovernorateAges 20–60 - NCT04195256RecruitingPhase 2/Phase 3
Nasal sedation medicine for kids needing a quick procedure
This trial tests whether a nose spray (dexmedetomidine plus ketamine) can safely and effectively sedate children during an ED procedure for certain arm injuries. It may help reduce distress and improve comfort compared with usual care.
Edmonton, AlbertaAges 2–17 - NCT07626346Recruiting
Pain relief medication added to shoulder surgery nerve block
This trial tests whether adding a medication called dexmedetomidine to a numbing injection around shoulder nerves can improve pain control after laparoscopic shoulder surgery. The goal is to see if this combination works better than the numbing medication alone.
CairoAges 18–65 - NCT05849597RecruitingPhase 3
Dexmedetomidine to prevent delirium after open-heart surgery
This trial tests whether a sedating medicine called dexmedetomidine can reduce the risk of “delirium” (sudden confusion) in the intensive care unit after open-heart surgery. If you’re having certain heart operations, it may help protect your thinking and alertness during recovery.
KamenitzAges 18 years+ - NCT07590752RecruitingPhase 2/Phase 3
Pain Relief Comparison for Abdominal Surgery
This trial compares two medications added to a numbing injection around your abdominal muscles during belly surgery to help manage pain after surgery. The study aims to find which combination works better and lasts longer.
Sahiwal, Punjab ProvinceAges 25–65 - NCT07564531Recruiting
Safe sedation for heart catheterization in children
This study tests whether a combination of two sedative medications (dexmedetomidine and ketamine) works safely and effectively to keep children calm and still during heart catheterization—a procedure where a thin tube is guided through blood vessels to the heart for diagnosis or treatment.
HanoiAges Up to 18 years - NCT07557576Recruiting
Pain management approaches for children having cleft surgery
This study compares two types of anesthesia (with and without opioid painkillers) for children undergoing cleft lip or palate surgery. The goal is to see which approach better controls pain after surgery and reduces agitation as the child wakes up.
ZagrebAges 3 months–7 years - NCT07556523RecruitingPhase 4
Recovery quality after heart valve replacement with different sedation
This study compares how well patients recover after a minimally invasive heart valve procedure (TAVR) when given different types of sedation. The goal is to find which sedation approach helps patients feel better and recover faster after the procedure.
Glenview, IllinoisAges 18–90 - NCT06752616RecruitingPhase 2/Phase 3
Study on calming severe agitation in psychiatric emergency rooms
This trial tests two different medications to quickly calm severe agitation in people admitted to a psychiatric emergency room. You may be able to join if you are extremely agitated and need urgent medication to help you settle down.
Copenhagen NAges 18–64 - NCT03426579Recruiting
Testing sedation monitoring during anesthesia for children’s throat surgery
This trial looks at whether a monitoring method for how deeply a child is sedated matches how the child’s reflexes react during intravenous anesthesia. It may help anesthesiologists keep children safer and more comfortable during direct laryngoscopy procedures using medications like dexmedetomidine and remifentanil.
Edegem, AntwerpAges 1 month–8 years - NCT07389096RecruitingPhase 4
Pain relief without opioids for teens having spine surgery
This trial tests if a drug combination that avoids opioids can safely control pain during and after scoliosis surgery in teenagers. It aims to reduce opioid side effects and improve recovery.
Port SaidAges 8–18 - NCT07392177RecruitingPhase 2
Understanding the brain's role in insomnia
This trial tests whether a part of the brain called the locus coeruleus is involved in insomnia. It involves sleep questionnaires and possibly brain imaging to understand your sleep problems better.
Macquarie Park, New South WalesAges 30–65 - NCT07380139Enrolling by invitationPhase 1
Comparing two medications for nose surgery pain relief
This trial tests if two different medicines, dexamethasone and dexmedetomidine, given as a nerve block in your nose during rhinoplasty can better control pain after surgery.
CairoAges 18–65 - NCT07330999Recruiting
PENG block variants with and without extra medications for older adults undergoing hip surgery
This trial tests three ways of doing a PENG block (a type of pain relief injection for hip surgery) with or without added medications (adjuvants) to see which works best for older adults. It aims to improve pain control and reduce the need for other pain medicines after surgery.
PoznanAges 65–100 - NCT07259460Recruiting
Dexmedetomidine effects during propofol anesthesia
This study tests whether adding a sedative called dexmedetomidine changes brain activity during general anesthesia. It aims to improve how anesthesia is given.
Treviso, TVAges 18–80 - NCT07184801RecruitingPhase 3
Comparing two sedatives for medical thoracoscopy
This trial tests if dexmedetomidate or midazolam is safer and works better for sedation during a medical thoracoscopy, a procedure to look inside the chest. It may help you if you need this procedure for an unclear pleural effusion.
Chandigarh, ChandigarhAges 12–90 - NCT07174440Recruiting
Testing numbing medicine for spine surgery
This trial is testing a numbing medicine placed near the spine (erector spinae block) during lumbar spine fusion surgery. It aims to see if it helps control pain and may reduce the amount of anesthetic needed during the procedure.
Cleveland, OhioAges 21–75 - NCT05383495RecruitingPhase 3
Calming medicine during child laceration repair
This trial tests a calming/anxiety-reducing medicine to see if it helps children feel less scared during stitches for a skin cut. It may help make the repair process easier for children and their caregivers.
London, OntarioAges 2–12 - NCT07145697RecruitingPhase 4
EEG study of anesthesia and consciousness in epilepsy
This trial tests how anesthesia affects brain activity in people with drug-resistant epilepsy who need brain electrode monitoring. It may help us understand consciousness and improve anesthesia safety.
Guangzhou, GuangdongAges 3–65 - NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+ - NCT06943404RecruitingPhase 2
BXCL501 after a car crash to help recovery
This study tests a medication called BXCL501 to see if it helps people recover from stress after a motor vehicle crash. You can join if you went to the emergency room within 3 days of the crash and are expected to go home.
Jacksonville, FloridaAges 18–65 - NCT06875427RecruitingPhase 3
Nerve block vs no block for ACL surgery in kids
This trial tests whether a nerve block (a numbing shot) before ACL reconstruction helps young patients have less pain and better recovery compared to no block.
Hamilton, OntarioAges 10–18 - NCT06867289Recruiting
Nasal sedation study for children during brain MRI
This trial tests a nasal spray sedative (dexmedetomidine) to help children stay calm during a brain MRI. It may be an option if your child struggles with the scan due to age or cooperation issues.
MetzAges 1–18 - NCT06823349RecruitingPhase 4
Pain relief study for normal labor
This trial compares a single injection of pain medicine into the spinal fluid to other methods during normal labor. It aims to see how well it works for women in active labor with a single, full-term baby in head-down position.
AswānAges Any age
Common questions
- Are there clinical trials studying Dexmedetomidine?
- Yes. Clin2 currently lists 178 recruiting studies that include Dexmedetomidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dexmedetomidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dexmedetomidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dexmedetomidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.