Treatment
Dose Escalation clinical trials
We’re tracking 186 recruiting studies that include Dose Escalation, each written for real people, not researchers, below.
Recruiting studies
- NCT07593820RecruitingPhase 1
CAR-T Cell Study for Advanced HER2-Positive Cancers
This early-stage trial tests a new type of immune cell therapy called CAR-T cells, which are designed to recognize and attack cancer cells that have a protein called HER2. The cells are made from your own immune cells, trained in the laboratory, and given back to you. The study evaluates how safe the treatment is and whether it can shrink tumors.
Barcelona, CataloniaAges 18 years+ - NCT07601646RecruitingPhase 2
New Paste Treatment for Erectile Dysfunction
This trial tests a new alprostadil paste applied inside the urethra (the tube you urinate through) to help men with erectile dysfunction who haven't responded well to pills like Viagra. The goal is to find the right dose that safely improves erections.
Vancouver, British ColumbiaAges 21–75 - NCT07649928RecruitingEarly Phase 1
Testing ES502 for Advanced Pancreatic and Other Cancers
This early-stage trial tests a new drug called ES502 for patients with advanced cancers (including pancreatic cancer) that have a specific genetic mutation and certain immune markers. The study aims to find the right dose and see if it helps shrink tumors.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07650968RecruitingPhase 4
Prostate Medication Adjustment After Sudden Inability to Urinate
This trial tests whether increasing your prostate medication (tamsulosin) or switching to a different medication (silodosin) helps you urinate normally again after a sudden blockage caused by an enlarged prostate. The goal is to help you avoid long-term catheter use.
Banī Suwayf, Beni Suweif GovernorateAges 50 years+ - NCT06750289RecruitingPhase 3
Testing benralizumab for uncontrolled eosinophilic asthma
This study tests if adding a new injectable medicine (benralizumab) to your current medium-dose inhaler works better than simply increasing your inhaler dose to control hard-to-treat asthma. It may help people with a specific type of asthma linked to high eosinophil levels.
Chandler, ArizonaAges 12–75 - NCT05749276RecruitingPhase 1
Daratumumab with chemo for older adults with high-risk AML
This Phase 1 study tests whether adding daratumumab to standard intensive chemotherapy (idarubicin and cytarabine) works safely in people age 60 or older with a higher-risk form of acute myeloid leukemia (AML). It may help improve outcomes, but the main goal is to find the best dosing and safety in this age group.
NantesAges 60 years+ - NCT06821191RecruitingPhase 4
Safer blood thinner plan after heart stent
This trial is testing whether lowering the dose of your current blood thinner or switching to a different one (clopidogrel) is safer and works just as well after you've had a stent placed. It's designed for people who are already on two blood thinners and are doing well.
Jacksonville, FloridaAges 18 years+ - NCT07025148RecruitingPhase 4
Comparing two blood thinners after stenting for high-risk patients
This trial tests switching from a standard blood thinner (clopidogrel) to a lower dose of a stronger one (prasugrel) in people who have had a stent placed and are at high risk for both bleeding and heart problems. The goal is to see if the switch better prevents clots while keeping bleeding risks low.
Jacksonville, FloridaAges 18 years+ - NCT05709496Recruiting
Lowering prostate radiation dose for MRI-visible tumors
This trial tests whether men with certain prostate cancer seen on MRI can safely receive a lower dose of radiation. The goal is to keep cancer control while possibly reducing side effects.
Sutton, SurreyAges 18 years+ - NCT06307015Recruiting
Lowering radiation dose for HPV-related throat cancer using a special PET scan
This trial tests whether a special PET scan (FMISO PET) can help safely lower the radiation dose for patients with HPV-positive throat cancer. The goal is to reduce side effects while still effectively treating the cancer.
Saint Leonards, New South WalesAges 18 years+ - NCT06638541Recruiting
Lowering radiation dose for prostate cancer using MRI-guided machine
This trial tests if giving fewer radiation treatments using a special MRI-guided machine is safe and effective for men with prostate cancer. It may help reduce side effects while still controlling the cancer.
TorontoAges 18 years+ - NCT05681260RecruitingPhase 3
Methotrexate dose comparison for newly diagnosed T-cell lymphoma
This Phase 3 trial compares a higher dose of methotrexate versus an escalating (step-up) methotrexate plan in children newly diagnosed with T-cell lymphoblastic lymphoma. The goal is to see which dosing approach works better and is safe enough to use as standard treatment.
Shanghai, Shanghai MunicipalityAges 1–18 - NCT06043817RecruitingPhase 1/Phase 2
Study of STX-721 for advanced lung cancer with EGFR or HER2 changes
This trial tests a new drug, STX-721, for people with advanced non-small cell lung cancer that has a specific genetic change (EGFR or HER2 exon 20 insertion). The study aims to see if the drug is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT06116526RecruitingPhase 4
Reducing Dupixent in kids with well-controlled eczema
This study looks at whether children with well-controlled eczema can safely reduce how often they take Dupixent. It aims to find the lowest effective dose to keep eczema under control.
Baltimore, MarylandAges 1–17 - NCT06092957RecruitingPhase 3
Reduced radiation after chemo-immunotherapy for high-risk nasopharyngeal cancer
This trial tests whether a lower dose of radiation, with or without additional chemo-immunotherapy, works as well as the standard full-dose chemoradiation for people with advanced nasopharyngeal cancer who had a complete response after initial chemo-immunotherapy.
Guangzhou, GuangdongAges 18–70 - NCT05854823Recruiting
Reduced radiation after surgery for advanced head and neck cancer
This trial looks at whether giving less (de-escalated) radiation after surgery is as effective and safer for people with locally advanced head and neck squamous cell carcinoma who had a strong response to treatment before surgery. If you had no remaining cancer or only very small amounts of cancer left in the surgical specimen, this approach may help reduce side effects while keeping control of the disease.
Zhuhai, GuangdongAges 18–70 - NCT06675214RecruitingPhase 3
Immunotherapy with modified radiation for advanced NPC
This trial tests a new way to give radiation therapy after immunotherapy and chemotherapy for people with advanced nasopharyngeal cancer (NPC) that has partially shrunk. It aims to see if a different radiation schedule works better and has fewer side effects.
Zhuhai, GuangdongAges 18–65 - NCT03215719RecruitingPhase 2
De-escalating treatment for HPV-positive throat cancer with low-risk signals
This Phase 2 trial tests whether people with HPV-positive oropharyngeal (throat) cancer who look “lower risk” can safely receive less intensive treatment. It uses HPV blood test results and cancer staging scans to guide whether treatment can be de-escalated.
New York, New YorkAges 18 years+
Common questions
- Are there clinical trials studying Dose Escalation?
- Yes. Clin2 currently lists 186 recruiting studies that include Dose Escalation, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dose Escalation trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dose Escalation an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dose Escalation or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.