Treatment
Insulin clinical trials
We’re tracking 345 recruiting studies that include Insulin, each written for real people, not researchers, below.
Recruiting studies
- NCT06072963RecruitingPhase 2
Combining insulin and semaglutide for memory in MCI with metabolic syndrome
This study tests if a combination of insulin and semaglutide (a diabetes drug) can improve memory and thinking in people with mild cognitive impairment (MCI) who also have metabolic syndrome (a cluster of health issues like large waist, high blood sugar, and high blood pressure). It aims to see if treating blood sugar problems helps protect the brain.
Ramat GanAges 60–90 - NCT04578652RecruitingPhase 3
Test fiber plus metformin for teen weight and insulin resistance
This trial studies whether adding fiber to metformin helps teens with severe obesity and insulin resistance improve how their bodies handle sugar. You might consider it if you’re a teen who isn’t yet diagnosed with type 2 diabetes and meets the specific lab and health criteria.
Edmonton, AlbertaAges 12–18 - NCT05950282Recruiting
Study of insulin sensitivity differences by age and PCOS status
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
Houston, TexasAges 18 years+ - NCT05933707Recruiting
Study tiny vesicles and how they affect insulin
This study looks at how very small particles in the body (“extracellular vesicles”) relate to insulin action and how the body handles sugar. It may help researchers understand why some people have better or worse insulin responses.
St Louis, MissouriAges 25–55 - NCT05806801Recruiting
Study how weight loss changes the body with or without exercise
This study looks at how your metabolism (how your body uses energy and controls blood sugar/fats) changes during weight loss, comparing weight loss alone versus weight loss plus exercise. It may help researchers understand what body changes happen with different approaches and why.
Ann Arbor, MichiganAges 18–40 - NCT05743868Recruiting
Study of how insulin resistance affects blood fats
This study looks at how differences in insulin resistance may change how the liver makes triglycerides (a type of blood fat). It may help researchers understand why some people have higher triglycerides and how to target them better.
AmsterdamAges 18–65 - NCT05470504RecruitingPhase 2
Pegvisomant for severe insulin resistance from rare fat or gene problems
This Phase 2 study tests pegvisomant, a medicine that blocks growth hormone, to see if it can improve severe insulin resistance in people with a specific genetic cause or a rare fat distribution condition. If you fit the rare diagnosis, the study may help clarify whether growth-hormone blocking can improve blood sugar and related health markers.
Bethesda, MarylandAges 18–70 - NCT05305794RecruitingPhase 3
Weekly shot to improve blood sugar control in double diabetes
This trial tests a weekly injection (similar to Ozempic) for people with type 1 diabetes who also have features of type 2 diabetes (often called 'double diabetes'). The goal is to see if this extra treatment can help lower blood sugar and improve overall diabetes management.
DijonAges 18 years+ - NCT03818178Recruiting
Study of gut-delivered fats and insulin resistance
This study looks at how sending certain fats through the intestine affects “insulin resistance,” a condition where the body doesn’t use insulin as well. If you qualify, you may receive a controlled lipid (fat) delivery as part of measuring body fat handling and related body chemistry.
Rochester, MinnesotaAges 18–55 - NCT04607096Recruiting
Intermittent fasting to improve insulin in prediabetes or early type 2
This study tests whether intermittent fasting can improve how your body releases and uses insulin if you have prediabetes or early type 2 diabetes. It may help your blood sugar control without using insulin.
BerlinAges 18–70 - NCT03407833Enrolling by invitation
Study changes in the body after weight, gut, or liver treatment
This study looks at how the body’s insulin-sensitivity (how well your body uses sugar/insulin) and organ function change after certain medical procedures. It may help researchers understand why some people improve after surgery or liver transplant and guide future care.
Nashville, TennesseeAges 18 years+ - NCT02193295Recruiting
Testing how changing fats affects insulin resistance
This study tests how “lipid” (fat) changes in the body affect insulin resistance, which is when the body doesn’t respond to insulin as well as it should. Because it’s done in healthy people, it’s mainly looking at basic biology and may help guide future treatments.
New Haven, ConnecticutAges 18–90 - NCT00001987Recruiting
Understanding genetics of insulin resistance and diabetes
This research study looks at the genes and immune system factors that cause severe insulin resistance—a condition where the body doesn't respond well to insulin. Researchers want to understand why some people develop this problem and study family members and healthy volunteers to learn more.
Bethesda, MarylandAges 6 months–120 years - NCT03784651Recruiting
How breast cancer treatment changes metabolism and bone
This study looks at how standard breast cancer treatments affect your body’s metabolism and bones in postmenopausal people with early-stage breast cancer. It may help doctors better predict and prevent bone and metabolic side effects from treatment.
Copenhagen, DanmarkAges 50–70 - NCT02947503RecruitingPhase 3
Metformin for gestational diabetes in pregnancy outcomes
This study tests whether taking metformin during pregnancy improves outcomes for people with gestational diabetes. It may help with pregnancy health and baby outcomes compared with the study’s other diabetes care plan.
GroningenAges 18–45 - NCT05307367Recruiting
Study exercise and body muscle changes in advanced lung cancer
This study looks at why cancer can cause loss of muscle in people with advanced non–small cell lung cancer, and whether exercise can improve or explain those muscle changes. You may be asked to do physical testing and answer questionnaires while receiving standard palliative cancer treatment.
Copenhagen, DKAges 18–100 - NCT05221359Recruiting
Safety trial of ExOlin® for adults with hard-to-control type 1 diabetes
This trial checks whether ExOlin® is safe in adults with type 1 diabetes who have had difficult blood sugar control or injection-site skin problems despite insulin pump and continuous glucose monitoring. It’s mainly looking for safety and comfort while using the treatment devices.
StrasbourgAges 18 years+ - NCT05597709Recruiting
Study diabetes patients to measure MAFLD in Jiangsu
This study checks how common a condition called MAFLD is among people with type 2 diabetes in Jiangsu, China. It may help doctors understand how often this liver-related problem occurs and guide future care for people with type 2 diabetes.
Nanjing, JiangsuAges 18 years+ - NCT05753657RecruitingEarly Phase 1
Testing insulin and blood sugar monitoring with pioglitazone
This early study tests whether adding pioglitazone, along with close blood-sugar (glucose/insulin) monitoring, can help control high insulin and high blood sugar in people starting alpelisib for metastatic breast cancer. It may help reduce blood-sugar side effects from alpelisib.
HaifaAges 18–85 - NCT05987631Recruiting
Predicting weight loss and health after weight loss surgery
This study looks at why some people lose more weight and improve their health more than others after bariatric surgery. It also has a subgroup that specifically studies people who are insulin resistant (a sign of prediabetes) to see how surgery affects their metabolism.
Gouda, South HollandAges 18–75 - NCT05046483Recruiting
Blood sugar study after a new heart attack
This study measures how your body handles sugar and related hormones in people after a new STEMI heart attack, and compares them with people who do not have diabetes or have prediabetes. The goal is to better understand metabolic changes after the event, which could help future care.
Düsseldorf, North Rhine-WestphaliaAges 18–80 - NCT05383092Recruiting
Exercise program for kids with cancer and healthy insulin
This trial studies an adapted exercise (physical activity) program for children starting treatment for cancer to see if it can improve insulin sensitivity. It may help kids feel better and support healthy body metabolism during treatment.
ToulouseAges 5–18 - NCT06061042Recruiting
Time-restricted eating for metabolic health
This study tests whether eating only during a specific time window each day can improve metabolic health in people with obesity and insulin resistance. If you have a high BMI and early signs of diabetes, this trial might help you understand a simple dietary change.
Amsterdam, North HollandAges 50–75 - NCT02208141Recruiting
Child body growth study with planned surgery
This study follows children’s body growth and fat (adipose) tissue as part of a planned surgical procedure. It aims to improve understanding of how fat tissue develops in childhood and what factors may affect health later.
Leipzig, SaxonyAges Any age
Common questions
- Are there clinical trials studying Insulin?
- Yes. Clin2 currently lists 345 recruiting studies that include Insulin, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Insulin trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Insulin an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Insulin or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.