Treatment
Low Dose clinical trials
We’re tracking 457 recruiting studies that include Low Dose, each written for real people, not researchers, below.
Recruiting studies
- NCT07331519Recruiting
Smoking cessation with lung cancer screening
This trial tests if combining smoking cessation support with a low-dose CT scan for lung cancer can help people quit. It is for long-term, heavy smokers who may be at higher risk for lung cancer.
HelsinkiAges 50–74 - NCT07525986RecruitingPhase 4
Pain control after laparoscopic colon surgery using a button-press system
This trial tests a new pain medication (anrikefon) that patients can control themselves by pressing a button after laparoscopic colon surgery. The goal is to see if it works better or safer than standard pain relief, especially for patients whose nerve blocks alone don't fully control pain.
Beijing, Beijing MunicipalityAges 18–75 - NCT07287033RecruitingPhase 1
Safety study of MY006 in healthy people and people with peanut allergy
This early-phase study tests a new investigational medication (MY006) to see if it is safe and how the body processes it. It is given to both healthy volunteers and people with peanut allergy. The goal is to gather safety information before larger trials.
Colorado Springs, ColoradoAges 12–55 - NCT05929612RecruitingPhase 2
Low-dose targeted radiation alone for marginal zone lymphoma
This Phase 2 study tests whether very low-dose radiation (adjusted based on how you respond) can treat marginal zone lymphoma without adding other medicines at first. It may help some people by reducing radiation exposure while still controlling the cancer.
Houston, TexasAges 18 years+ - NCT06758375RecruitingPhase 2
Low dose teclistamab for newly diagnosed multiple myeloma
This trial tests a lower dose of the drug teclistamab in people newly diagnosed with multiple myeloma. It aims to see if a lower dose is still effective and has fewer side effects.
Monterrey, Nuevo LeónAges 18 years+ - NCT06667999RecruitingPhase 4
Intensive care platform trial for adult ICU patients
This major trial tests multiple treatments at once for adults admitted to the ICU. If you are an ICU patient, you may be able to join and receive one of several possible treatments aimed at improving recovery.
AabenraaAges 18 years+ - NCT04474964Recruiting
Radiotherapy plus chemo for WNT medulloblastoma in children
This study tests whether adding a specific brain/spinal radiation plan (focused radiation plus low-dose spinal coverage) followed by chemotherapy works well for children with newly diagnosed WNT medulloblastoma after surgery. It targets kids whose remaining tumor after surgery is small and who have no spread to the spine or fluid.
Mumbai, MaharashtraAges 3–16 - NCT04577599Recruiting
Mobile low-dose lung CT screening for ages 40–54
This study offers mobile low-dose CT scans to help find lung problems early in people at higher risk from smoking. You may be invited because of your age and smoking history, and the results may guide next steps with your care team.
Charlotte, North CarolinaAges 40–54 - NCT05537935RecruitingPhase 4
Low-dose naltrexone for nerve pain in people with HIV
This trial studies whether a low dose of naltrexone can reduce long-lasting nerve-related pain in adults living with HIV. It may help if your pain has been ongoing and you have stable HIV control.
Atlanta, GeorgiaAges 18–75 - NCT06220552RecruitingPhase 2
Low-dose radiation plus immunotherapy for recurrent glioblastoma
This trial tests a combination of low-dose radiation, an immunotherapy drug (sintilimab), and chemotherapy (temozolomide) for people with glioblastoma that has come back. The goal is to see if this approach can help control the tumor and improve survival.
Zhuhai, GuangdongAges 18 years+ - NCT05557877RecruitingPhase 2
Low-dose aspirin to prevent postpartum breast cancer
This study tests whether taking a low dose of aspirin after childbirth can lower the chance of developing breast cancer later. You may be asked to provide blood, urine, and breast tissue samples so researchers can look for changes that could explain why aspirin may help.
Scottsdale, ArizonaAges 18–45 - NCT04250064RecruitingPhase 2
Low-dose bevacizumab with standard radiation for DIPG
This Phase 2 study tests whether adding low-dose bevacizumab (a medicine that affects blood vessel growth) to standard radiation can help children newly diagnosed with DIPG. It’s meant for certain children with a specific type of brain tumor that has not spread.
Mumbai, MaharashtraAges 3–18 - NCT06874192RecruitingPhase 1
Low-dose colchicine for statin intolerance pilot study
This trial tests if a low dose of colchicine can help people who cannot take statins due to side effects. It aims to see if colchicine is safe and effective for lowering inflammation and improving cholesterol management.
Richmond, VirginiaAges 18–80 - NCT07693140RecruitingPhase 1/Phase 2
Low-dose radiation therapy for Alzheimer's disease
This trial tests if very low doses of radiation to the brain can reduce inflammation and slow memory loss in people with Alzheimer's or similar dementias. It involves monthly clinic visits for a year.
Winter Park, FloridaAges 50 years+ - NCT06603402RecruitingPhase 2
Low-dose radiation plus immunotherapy for esophageal cancer
This trial tests a combination of low-dose radiation and immunotherapy for people with advanced esophageal cancer that cannot be surgically removed. The goal is to see if this approach is safe and effective after initial treatment.
Chengdu, SichuanAges 18–80 - NCT06446726RecruitingPhase 2
Low-dose radiation, chemo, and immunotherapy before esophageal cancer surgery
This trial tests a combination of low-dose radiation, chemotherapy, and immunotherapy before surgery for esophageal cancer. The goal is to see if this approach helps shrink the tumor and improve outcomes.
Chengdu, SichuanAges 18–75 - NCT06667154RecruitingPhase 2
Low-dose nivolumab plus chemo for early lung cancer
This trial tests a lower dose of the immunotherapy drug nivolumab (Opdivo) combined with standard chemotherapy before surgery for patients with early-stage non-small cell lung cancer (NSCLC). The goal is to see if this combination shrinks the tumor and improves outcomes with fewer side effects.
São José do Rio Preto, São PauloAges 18 years+ - NCT07448142RecruitingPhase 2
Low-dose radiation plus immunotherapy and chemo for rectal cancer
This trial tests whether adding a very low dose of radiation to a combination of immunotherapy (pucotenlimab) and chemotherapy (CAPEOX) can help shrink rectal cancer tumors that have not spread. It is for people with locally advanced rectal cancer that is pMMR (meaning the cancer cells have normal DNA repair).
Guangzhou, GuanggongAges 18–75 - NCT05722405RecruitingPhase 4
Ixazomib plus lenalidomide compared to ixazomib alone for myeloma maintenance
This trial studies whether adding low-dose lenalidomide to ixazomib can help keep high-risk multiple myeloma from coming back after initial treatment. It may help prolong the time before the disease worsens, while also checking side effects.
Hangzhou, ZhejiangAges 18–80 - NCT06714708RecruitingPhase 2
Low-dose radiation with immunotherapy and chemo before surgery for lung cancer
This trial tests a combination of low-dose radiation, an immunotherapy drug called sintilimab, and standard chemotherapy before surgery for stage II–III non-small cell lung cancer (NSCLC). The goal is to see if this approach can shrink tumors and improve outcomes for patients who are candidates for surgery.
Hefei, AnhuiAges 18 years+ - NCT05343325RecruitingPhase 2
Neoadjuvant low-dose radiation with chemo-immunotherapy for head and neck cancer
This Phase 2 study tests whether giving low-dose radiation before surgery—along with chemotherapy and an immunotherapy drug—can work better and be safe for treating locally advanced head and neck squamous cell cancer. It may help shrink tumors before surgery and reduce the chance of the cancer coming back.
Zhuhai, GuangdongAges 18–70 - NCT07039877RecruitingPhase 2
Low-dose venetoclax with itraconazole and TACL for relapsed or refractory ALL
This trial tests a combination of low-dose venetoclax (a targeted cancer pill) plus itraconazole (an antifungal) and chemotherapy drugs for adults with acute lymphoblastic leukemia (ALL) that has come back or hasn't responded to first treatment.
Monterrey, Nuevo LeónAges 16–45 - NCT06960928RecruitingPhase 3
Low dose sirolimus for long COVID
This trial tests if a low dose of sirolimus, a medicine that calms the immune system, can help people with long COVID. If you have had long COVID symptoms for at least 6 months, like severe fatigue, brain fog, or chest pain, you may be able to join.
New York, New YorkAges 18 years+ - NCT06494995RecruitingPhase 2
AK104 and low-dose radiation for advanced head and neck cancer
This trial tests a new immunotherapy drug called AK104 (cadonilimab) combined with low-dose radiation for people with head and neck or nasopharyngeal cancer that has come back or spread and no longer responds to first treatment. The goal is to see if this combination can shrink tumors or stop them from growing.
Shanghai, Shanghai MunicipalityAges 18–75
Common questions
- Are there clinical trials studying Low Dose?
- Yes. Clin2 currently lists 457 recruiting studies that include Low Dose, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Low Dose trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Low Dose an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Low Dose or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.