Treatment
Progesterone clinical trials
We’re tracking 51 recruiting studies that include Progesterone, each written for real people, not researchers, below.
Recruiting studies
- NCT06896617RecruitingPhase 4
Corpus Luteum's effect on frozen embryo transfer pregnancies
This study looks at whether having a corpus luteum (the structure left after an egg is released) affects pregnancy outcomes in frozen embryo transfer cycles. It aims to help doctors choose the best way to prepare the body for embryo transfer.
Barcelona, SpainAges 18–41 - NCT07620067Recruiting
GnRH Hormone for IVF Embryo Support
This study tests whether a hormone called GnRH can improve success rates during IVF (in vitro fertilization) by supporting the embryo after transfer. If you're having IVF for the first to third time and your doctor is considering different support methods, this trial may explore options for you.
JerusalemAges 18–45 - NCT07028710Recruiting
Progesterone changes after hCG-triggered ovulation in natural cycles
This study looks at how progesterone levels change in the early part of the luteal phase (after ovulation) when ovulation is triggered by an hCG injection in a natural cycle. It may help women undergoing routine ovulation induction understand how their body responds.
MontpellierAges Any age - NCT07745036Recruiting
Progesterone receptors in preeclampsia
This study looks at how certain hormone receptors might be linked to preeclampsia, a pregnancy complication involving high blood pressure. It aims to understand why some women get preeclampsia and could help improve care in the future.
SamsunAges 18–45 - NCT02989025RecruitingPhase 2
Progesterone for some preterm preeclampsia pregnancies
This trial tests whether taking progesterone can improve outcomes for people with preeclampsia that is being managed without immediate delivery. It’s meant for pregnancies in a specific gestational age window and when both mother and baby are stable enough for “expectant management.”
Jackson, MississippiAges 18–45 - NCT03068910RecruitingEarly Phase 1
Study of hormone timing in teens with high androgens
This early study looks at how certain “male-type” hormones and brain signals (measured through hormone patterns during the day and night) work in adolescent girls with high androgen levels. It may help researchers better understand causes like PCOS and related hormone timing differences.
Charlottesville, VirginiaAges 10–17 - NCT03463252RecruitingPhase 2/Phase 3
Hormone IUD to preserve fertility in early uterine cancer
This study looks at whether a hormone-releasing IUD (LNG-IUS) can treat early-stage endometrial cancer or very early abnormal cell growth while helping you keep the option for future pregnancy. It aims to see how well the treatment works and how it affects fertility-related outcomes.
Chengdu, SichuanAges Up to 40 years - NCT05282277RecruitingPhase 4
Estradiol to improve brain and reward changes in midlife women
This study tests whether a hormone called estradiol (given as a patch and pill) changes how the brain and body respond to reward in some midlife women with low pleasure and/or psychosis symptoms during menopause transition. It may help researchers understand whether estrogen treatment can improve mood-related “reward” function in this group.
Chapel Hill, North CarolinaAges 45–55 - NCT05316935RecruitingPhase 2/Phase 3
Hormone therapy for certain early uterine lining cancers without obesity
This trial tests whether adding GnRH medicine and letrozole to standard progestin treatment can better control early, low-risk endometrial cancer or atypical hyperplasia in people who are not obese. It may help some patients avoid progression while keeping the uterus, especially for those wanting future fertility.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT05647109Recruiting
Test tumor-like cell clusters to predict progesterone response
This study looks at small lab samples taken from early endometrial cancer to see how sensitive the tumor is to progesterone treatment. It may help doctors choose the safest treatment that preserves fertility and the uterus for the right patients.
Beijing, Beijing MunicipalityAges 17–45 - NCT05704036RecruitingPhase 4
Estrogen use and bone health in women with cystic fibrosis
This observational study looks at how taking (or not taking) estrogen affects bone health in women with cystic fibrosis (CF). If you may have low estrogen, it also explores whether estrogen levels and symptoms relate to bone density over time.
Baltimore, MarylandAges birth–100 years - NCT05750849Recruiting
Checks progesterone levels to predict pregnancy in fertility treatment
This study looks at whether a blood progesterone level around the time of a pregnancy test during fertility treatment helps predict which patients will have an ongoing pregnancy. It may help doctors better understand who is most likely to continue developing a pregnancy during artificial cycles.
Valencia, ValenciaAges 18–50 - NCT05868226RecruitingPhase 1
Early cancer drug study for adults with advanced tumors
This Phase 1 study tests early (first-in-program) cancer medicines in people whose cancer has not been adequately controlled. It helps researchers learn the safest dose and early signs of whether the treatment may work for different tumor types and treatments.
Birmingham, AlabamaAges 18 years+ - NCT05913427RecruitingPhase 2
Progesterone added to chemo for adrenal cancer that spread
This Phase 2 trial tests whether adding progesterone to standard chemotherapy improves outcomes for people with adrenal cortical carcinoma (ACC) that is locally advanced or has spread and cannot be removed with surgery. It also checks whether the treatment is safe and tolerable.
BresciaAges 18 years+ - NCT05969795RecruitingPhase 1
Natural embryo transfer with or without progesterone support
This Phase 1 study compares pregnancy outcomes, especially live birth, when using a natural-cycle frozen embryo transfer with an embryo that is genetically euploid (normal chromosome number) versus doing transfers without luteal (progesterone) phase support. It may help determine whether adding progesterone around ovulation improves the chance of a live birth.
Abu DhabiAges 18–40 - NCT06036446Recruiting
Late cerclage for preventing early birth in high-risk pregnancies
This trial tests if placing a stitch in the cervix (cerclage) between 24 and 27 weeks of pregnancy can help prevent preterm birth in women whose cervix is short. It may be an option for those who find out late in pregnancy that they are at risk.
Charlotte, North CarolinaAges 18–50 - NCT06102863RecruitingPhase 2
Progesterone and statins for young women with early endometrial cancer or atypical hyperplasia
This trial tests whether adding a statin to progesterone therapy helps young women with early endometrial cancer or atypical endometrial hyperplasia who want to preserve their fertility. It aims to find a better treatment option for those who may not respond well to progesterone alone.
Beijing, Beijing MunicipalityAges 17–45 - NCT06357442Recruiting
Comparing progesterone methods for young people on estrogen therapy
This study compares two ways to give progesterone to young people on estrogen replacement therapy to see how they affect the lining of the uterus. It will help find which approach may be safer and more effective for your health.
Aurora, ColoradoAges 12–25 - NCT06379113RecruitingPhase 2/Phase 3
Hormone therapy for obesity-linked endometrial cancer that didn't respond to progestin
This trial tests a combination of two hormone-blocking drugs (GnRHa plus letrozole) for women with early-stage, obesity-related endometrial cancer who haven't responded well to standard hormone therapy alone. The goal is to preserve the uterus and fertility while controlling the cancer.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT06401889Recruiting
Skin care program for breast cancer survivors on hormone therapy
This study tests whether a skin care program can improve the appearance of your skin and your quality of life while you take an aromatase inhibitor (a hormone therapy) after breast cancer treatment. It is designed for women who are starting this type of therapy for the first time.
Jacksonville, FloridaAges 18 years+ - NCT06586957RecruitingPhase 1
Study of NKT3964 for advanced solid tumors
This trial is testing an experimental oral drug called NKT3964 for people with advanced solid tumors that have stopped responding to standard treatments. The drug works by blocking a protein called CDK2, which some cancers need to grow.
Little Rock, ArkansasAges 18 years+ - NCT06610305RecruitingPhase 4
Hormones, mood, and reward in women with PMS-related depression
This study looks at how changes in hormone levels during the menstrual cycle affect mood and the brain's reward system in women with depression that gets worse before their period. The goal is to understand why this happens so better treatments can be developed.
Chapel Hill, North CarolinaAges 18–45 - NCT06851754RecruitingPhase 3
Hormone therapy for teens with early menopause
This trial tests whether hormone replacement therapy (HRT) helps protect bone health in teenagers with premature ovarian insufficiency (POI). It compares HRT to a placebo and also includes healthy volunteers for comparison.
Bethesda, MarylandAges 11–19 - NCT07242131Recruiting
Birth control, progesterone, or inositol for regulating periods in PCOS
This trial tests three treatments—birth control pills, progesterone, and inositol—to see which best helps regulate menstrual cycles in women with PCOS. It aims to find an effective option that is safe and easy to use.
Izmir, MenemenAges 18–40
Common questions
- Are there clinical trials studying Progesterone?
- Yes. Clin2 currently lists 51 recruiting studies that include Progesterone, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Progesterone trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Progesterone an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Progesterone or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.