Treatment
Progesterone clinical trials
We’re tracking 54 recruiting studies that include Progesterone, each written for real people, not researchers, below.
Recruiting studies
- NCT06357442Recruiting
Comparing progesterone methods for young people on estrogen therapy
This study compares two ways to give progesterone to young people on estrogen replacement therapy to see how they affect the lining of the uterus. It will help find which approach may be safer and more effective for your health.
Aurora, ColoradoAges 12–25 - NCT05969795RecruitingPhase 1
Natural embryo transfer with or without progesterone support
This Phase 1 study compares pregnancy outcomes, especially live birth, when using a natural-cycle frozen embryo transfer with an embryo that is genetically euploid (normal chromosome number) versus doing transfers without luteal (progesterone) phase support. It may help determine whether adding progesterone around ovulation improves the chance of a live birth.
Abu DhabiAges 18–40 - NCT07436793RecruitingPhase 2
Progestin therapy before hysterectomy for endometrial cancer
This trial tests whether taking progestin (a hormone medication) before scheduled surgery can improve outcomes for women with a type of uterine cancer called endometrioid adenocarcinoma. You might be able to join if you are planning to have a hysterectomy and are open to hormone therapy before the procedure.
Iowa City, IowaAges 18 years+ - NCT07425990Recruiting
Comparing natural cycle types for frozen embryo transfer
This study compares two types of natural cycle preparation for frozen embryo transfers to see which leads to more pregnancies. It may be a good fit if you are using your own eggs, have regular cycles, and are planning a frozen embryo transfer.
Novi SadAges 18–40 - NCT07388797Recruiting
Progesterone levels and pregnancy in frozen embryo transfer
This study looks at how progesterone levels on the day of embryo transfer affect the chance of pregnancy in frozen embryo transfer (FET) cycles. It aims to find if certain levels can improve outcomes for patients.
Hong KongAges 18–42 - NCT07340827RecruitingPhase 3
Comparing two fertility drugs in Japanese women with hormone deficiency
This study tests if a combination of two hormone drugs (follitropin alfa/lutropin alfa) works as well as another drug (hMG) for Japanese women with low LH and FSH levels who are doing in vitro fertilization (IVF). The goal is to help them produce eggs for pregnancy.
Akita, AkitaAges 18–42 - NCT07305519Recruiting
Can supplements prevent early birth for short cervix?
This study tests if taking a combination of magnesium, a natural supplement (palmitoylethanolamide), hyaluronic acid, and vitamins B6 and D can help prevent preterm birth in women with a shorter-than-ideal cervix.
Rome, RMAges 18 years+ - NCT07242131Recruiting
Birth control, progesterone, or inositol for regulating periods in PCOS
This trial tests three treatments—birth control pills, progesterone, and inositol—to see which best helps regulate menstrual cycles in women with PCOS. It aims to find an effective option that is safe and easy to use.
Izmir, MenemenAges 18–40 - NCT06896617RecruitingPhase 4
Corpus Luteum's effect on frozen embryo transfer pregnancies
This study looks at whether having a corpus luteum (the structure left after an egg is released) affects pregnancy outcomes in frozen embryo transfer cycles. It aims to help doctors choose the best way to prepare the body for embryo transfer.
Barcelona, SpainAges 18–41 - NCT06102863RecruitingPhase 2
Progesterone and statins for young women with early endometrial cancer or atypical hyperplasia
This trial tests whether adding a statin to progesterone therapy helps young women with early endometrial cancer or atypical endometrial hyperplasia who want to preserve their fertility. It aims to find a better treatment option for those who may not respond well to progesterone alone.
Beijing, Beijing MunicipalityAges 17–45 - NCT05647109Recruiting
Test tumor-like cell clusters to predict progesterone response
This study looks at small lab samples taken from early endometrial cancer to see how sensitive the tumor is to progesterone treatment. It may help doctors choose the safest treatment that preserves fertility and the uterus for the right patients.
Beijing, Beijing MunicipalityAges 17–45 - NCT07028710Recruiting
Progesterone changes after hCG-triggered ovulation in natural cycles
This study looks at how progesterone levels change in the early part of the luteal phase (after ovulation) when ovulation is triggered by an hCG injection in a natural cycle. It may help women undergoing routine ovulation induction understand how their body responds.
MontpellierAges Any age - NCT06851754RecruitingPhase 3
Hormone therapy for teens with early menopause
This trial tests whether hormone replacement therapy (HRT) helps protect bone health in teenagers with premature ovarian insufficiency (POI). It compares HRT to a placebo and also includes healthy volunteers for comparison.
Bethesda, MarylandAges 11–19 - NCT05750849Recruiting
Checks progesterone levels to predict pregnancy in fertility treatment
This study looks at whether a blood progesterone level around the time of a pregnancy test during fertility treatment helps predict which patients will have an ongoing pregnancy. It may help doctors better understand who is most likely to continue developing a pregnancy during artificial cycles.
Valencia, ValenciaAges 18–50 - NCT03068910RecruitingEarly Phase 1
Study of hormone timing in teens with high androgens
This early study looks at how certain “male-type” hormones and brain signals (measured through hormone patterns during the day and night) work in adolescent girls with high androgen levels. It may help researchers better understand causes like PCOS and related hormone timing differences.
Charlottesville, VirginiaAges 10–17 - NCT06610305RecruitingPhase 4
Hormones, mood, and reward in women with PMS-related depression
This study looks at how changes in hormone levels during the menstrual cycle affect mood and the brain's reward system in women with depression that gets worse before their period. The goal is to understand why this happens so better treatments can be developed.
Chapel Hill, North CarolinaAges 18–45 - NCT06150703RecruitingPhase 3
Luteal phase support with GnRH agonist after egg retrieval trigger
This trial tests whether giving a medication called a GnRH agonist during the luteal phase (the time after egg retrieval) can help with IVF success. It is for people who are using a specific medication protocol (recombinant FSH with an antagonist) and have certain hormone levels.
BondyAges 18–39 - NCT06549855Recruiting
PD-1 inhibitor plus progesterone for fertility preservation in MMRd endometrial cancer
This trial tests a combination of an immunotherapy drug (PD-1 inhibitor) and progesterone hormone therapy to treat early-stage, MMR-deficient endometrial cancer while preserving fertility. It may help young women who want to keep the option to have children in the future.
Beijing, Beijing MunicipalityAges 18–45 - NCT06526520Recruiting
Relaxin levels in frozen embryo transfer preparation
This study looks at a hormone called relaxin during different ways of preparing the uterus for a frozen embryo transfer. It may help understand which preparation method works best for women who are not trying to get pregnant right now.
Abu Dhabi, Abu Dhabi EmirateAges 18–35 - NCT06401889Recruiting
Skin care program for breast cancer survivors on hormone therapy
This study tests whether a skin care program can improve the appearance of your skin and your quality of life while you take an aromatase inhibitor (a hormone therapy) after breast cancer treatment. It is designed for women who are starting this type of therapy for the first time.
Jacksonville, FloridaAges 18 years+ - NCT06379113RecruitingPhase 2/Phase 3
Hormone therapy for obesity-linked endometrial cancer that didn't respond to progestin
This trial tests a combination of two hormone-blocking drugs (GnRHa plus letrozole) for women with early-stage, obesity-related endometrial cancer who haven't responded well to standard hormone therapy alone. The goal is to preserve the uterus and fertility while controlling the cancer.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT05704036RecruitingPhase 4
Estrogen use and bone health in women with cystic fibrosis
This observational study looks at how taking (or not taking) estrogen affects bone health in women with cystic fibrosis (CF). If you may have low estrogen, it also explores whether estrogen levels and symptoms relate to bone density over time.
Baltimore, MarylandAges birth–100 years - NCT06036446Recruiting
Late cerclage for preventing early birth in high-risk pregnancies
This trial tests if placing a stitch in the cervix (cerclage) between 24 and 27 weeks of pregnancy can help prevent preterm birth in women whose cervix is short. It may be an option for those who find out late in pregnancy that they are at risk.
Charlotte, North CarolinaAges 18–50 - NCT05868226RecruitingPhase 1/Phase 2
Personalized cancer treatment study for advanced solid tumors
This study tests different treatments tailored to your cancer's biology. It aims to find which therapy might work best for you, potentially improving outcomes. You'd receive one of the study drugs, with close monitoring and support.
Birmingham, AlabamaAges 18 years+
Common questions
- Are there clinical trials studying Progesterone?
- Yes. Clin2 currently lists 54 recruiting studies that include Progesterone, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Progesterone trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Progesterone an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Progesterone or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.