Treatment
Systemic therapy clinical trials
We’re tracking 408 recruiting studies that include Systemic therapy, each written for real people, not researchers, below.
Recruiting studies
- NCT04090034Recruiting
PRRT for advanced neuroendocrine tumors
This trial tests a treatment called PRRT, which delivers a radioactive medicine directly to tumor cells, for advanced neuroendocrine tumors. It may help those whose tumors are growing despite octreotide treatment, especially when scans show tumor uptake of specific tracers.
Dallas, TexasAges 18 years+ - NCT07456852RecruitingPhase 1/Phase 2
Can vasodilators help with chemo side effects in GI cancer?
This trial tests two drugs (isosorbide mononitrate and diltiazem) to see if they can prevent blood vessel damage caused by chemotherapy drugs like 5-FU or capecitabine in people with gastrointestinal cancers.
Rochester, MinnesotaAges 18 years+ - NCT07089927Recruiting
Virtual art therapy for young cancer survivors with depression
This trial tests if virtual art therapy sessions can help adolescents and young adults who have had cancer feel better emotionally and socially. You may be eligible if you have mild or greater depression and had cancer in the past year or finished treatment within the last five years.
Scottsdale, ArizonaAges 10–25 - NCT07685327Recruiting
Mixed reality vs. physical therapy for balance in teens with cerebral palsy
This study compares two types of therapy to help teens with spastic diplegic cerebral palsy improve their balance and coordination. One group will use mixed reality (a blend of real and virtual environments) and the other group will do standard physical therapy exercises.
Mansehra, KpkAges 10–19 - NCT07075185RecruitingPhase 1
Gene therapy study for hard-to-treat multiple myeloma
This study tests a new gene therapy for people with multiple myeloma that has come back or stopped responding to at least 3 prior treatments. The therapy is designed to help your immune system fight the cancer cells more effectively.
Duarte, CaliforniaAges 18 years+ - NCT07220915RecruitingPhase 3
Study of Panzyga to prevent infections in people with weak immune systems
This trial tests if a medication called Panzyga can help prevent infections in people with autoimmune conditions who have low antibody levels after B-cell therapy. It may be an option if you have a condition like multiple sclerosis, rheumatoid arthritis, or lupus.
Scottsdale, ArizonaAges 18 years+ - NCT07288840Enrolling by invitation
Exercise plan for heart recovery monitored by heart rate
This study tests a special exercise program for people with heart disease or heart failure. The goal is to see if the exercises can help improve how your heart responds to activity and daily life.
Leiria, Leiria DistrictAges 18 years+ - NCT06254794Recruiting
Blood flow restriction rehab after Achilles tendon repair
This study tests whether adding blood flow restriction (BFR) to standard physical therapy helps people recover better after Achilles tendon repair surgery. You may be a good fit if you had a PARS or open repair and plan to rehab at a Methodist Hospital.
Houston, TexasAges 18 years+ - NCT05095909Recruiting
Frozen compression at intervals vs regular icing after shoulder surgery
This trial tests whether using a special device that gives cold in pulses (intermittent cryo-compression) helps the shoulder feel better after arthroscopic rotator cuff repair compared with traditional icing. It may help with pain and recovery during the early healing period after surgery.
Plymouth, MinnesotaAges 18–70 - NCT05134779Recruiting
Study aims to tailor cancer treatment to your biology
This study looks at how genes, the cancer environment, and your immune system interact to develop treatments that work better for people with breast cancer. It may help researchers learn why some treatments work for certain people and not others.
New York, New YorkAges 18–90 - NCT05201131Recruiting
Study of Rezūm treatment for enlarged prostate in Canadian patients
This study looks at outcomes from the Rezūm procedure for men with an enlarged prostate (BPH). You may be asked to complete questionnaires and follow the study plan to help researchers understand how well this treatment works and is tolerated.
Toronto, OntarioAges 18 years+ - NCT06427798RecruitingPhase 1/Phase 2
Radioactive drug for previously treated gut or adrenal tumors
This trial tests a new radioactive drug, [212Pb]VMT-alpha-NET, that targets a receptor found on some tumor cells. It is for people with certain gut or adrenal gland tumors that have already been treated with a similar therapy but are still growing.
Bethesda, MarylandAges 18–120 - NCT05744024Enrolling by invitation
VR-based comfort care during complex wound procedures
This trial studies a non-medicine way to reduce pain during complex wound care, possibly using VR or similar distraction tools. You may be able to join if you have painful wound procedures and can safely use the VR setup.
Amsterdam, North HollandAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Phoenix, ArizonaAges 18 years+ - NCT06807359RecruitingPhase 1/Phase 2
Light-activated therapy for localized prostate cancer
This trial uses a special light-activated drug (photodynamic therapy) to treat prostate cancer that is still confined to the prostate. It aims to destroy the cancer while sparing healthy tissue, and may be an option for people with intermediate-risk prostate cancer who have not had other treatments.
New York, New YorkAges 18 years+ - NCT07292961Recruiting
Exercise program for people with scleroderma
This study tests if a special exercise program based on your body and mind can help people with scleroderma feel better. It is for both children (ages 7-18) and adults.
Ankara, AltındağAges 7 years+ - NCT05304104Recruiting
Eating disorder care program for vets with binge problems
This trial looks at how to build a more fair and easy-to-access system of care for eating disorders within the VA and related groups. You may be able to take part if you are a VA user and have bulimia or binge eating, and can safely complete surveys and treatment planning.
West Haven, ConnecticutAges 18 years+ - NCT07720310Enrolling by invitation
CAR-T cell therapy for hard-to-treat lupus
This trial tests a new immune cell therapy (CAR-T) for people with lupus that hasn't gotten better with standard treatments. The goal is to see if these modified cells can calm the overactive immune system and improve symptoms.
Lyasny, Minsk OblastAges 18–70 - NCT06544343Recruiting
Remote monitoring for new immunosuppressive therapy
This trial tests whether regular remote check-ins can help manage chronic immunosuppressive medications. If you have an autoimmune condition like rheumatoid arthritis or lupus and are starting a new medicine such as methotrexate or a biologic, you may be eligible.
Perugia, PGAges Any age - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT06526858Recruiting
Laparoscopic kidney nerve treatment for resistant hypertension
This study tests a new treatment called HyperQure RDN, a laparoscopic (keyhole) surgery that targets nerves near the kidneys to lower blood pressure in people with resistant hypertension. If you have tried multiple medications but your blood pressure is still high, this procedure might offer an alternative approach.
Orange, CaliforniaAges 22–80 - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT07074470Recruiting
New drug combo for relapsed brain lymphoma
This trial tests a new combination of drugs (teniposide, a PD-1 checkpoint inhibitor, and selinexor) for people with relapsed or refractory primary central nervous system lymphoma. It aims to see if this three-drug approach can shrink tumors or slow the disease when previous treatments haven't worked.
Suzhou, JiangsuAges 18–75 - NCT06105580Recruiting
Pacing methods for heart failure with wide QRS
This trial compares two ways to pace the heart in people with heart failure and a wide QRS (a sign the heart's electrical signals are slowed). The goal is to see which method better reduces the risks of death, heart failure hospitalization, or needing a heart transplant.
BarcelonaAges 18 years+
Common questions
- Are there clinical trials studying Systemic therapy?
- Yes. Clin2 currently lists 408 recruiting studies that include Systemic therapy, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Systemic therapy trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Systemic therapy an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Systemic therapy or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.