Treatment
Tirzepatide clinical trials
We’re tracking 81 recruiting studies that include Tirzepatide, each written for real people, not researchers, below.
Recruiting studies
- NCT06727331RecruitingPhase 2
Tirzepatide for alcohol use recovery
This trial tests if tirzepatide, a medication that helps with appetite and blood sugar, can help people with alcohol use disorder drink less or stop drinking. You would visit the clinic regularly and receive the drug or a placebo.
Boston, MassachusettsAges 18 years+ - NCT06517212RecruitingPhase 2
Tirzepatide for weight loss in MRD-positive early breast cancer
This study tests whether the weight-loss drug tirzepatide (Mounjaro) can help prevent breast cancer from coming back in people who are overweight and have a sign of leftover cancer cells in their blood (called MRD-positive). You must have already finished at least one year of hormone therapy for early-stage breast cancer.
Dallas, TexasAges 18 years+ - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06657209RecruitingPhase 4
Comparing diabetes treatments for people with normal weight
This study tests two medications—pioglitazone (a pill) and tirzepatide (an injection)—in people with type 2 diabetes who have a normal body weight. It aims to find which treatment works better for this specific group.
Palo Alto, CaliforniaAges 30–70 - NCT06721507RecruitingPhase 4
Tirzepatide after weight loss surgery
This study tests whether giving tirzepatide (a medicine that helps with weight and blood sugar) right after weight loss surgery can improve results. It is for people who are already scheduled for sleeve gastrectomy or gastric bypass at UK HealthCare.
Lexington, KentuckyAges 18 years+ - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+ - NCT06802081RecruitingPhase 2
Tirzepatide for weight loss in people with atrial fibrillation
This study tests whether tirzepatide, a medication that helps with weight loss and blood sugar control, can improve the heart rhythm condition atrial fibrillation. If you have AFib and are overweight or obese, this trial may be an option for you.
Cleveland, OhioAges 18–80 - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+ - NCT06847399RecruitingPhase 2
Tirzepatide for Binge Eating Disorder
This trial tests if tirzepatide (a weekly injection) can help reduce binge eating compared to a placebo or another medication (lisdexamfetamine dimesylate). It may be a good fit for people with moderate or severe binge eating disorder who also have a high body weight.
Baltimore, MarylandAges 18 years+ - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Phoenix, ArizonaAges 18 years+ - NCT06864026RecruitingPhase 4
Adding tirzepatide to ixekizumab for psoriatic arthritis with weight concerns
This study tests adding tirzepatide (a once-weekly injection for weight and diabetes) to your current treatment with ixekizumab for psoriatic arthritis. It may help with both joint symptoms and weight.
Avondale, ArizonaAges 18 years+ - NCT06901245RecruitingPhase 4
Tirzepatide for young adults with obesity
This study tests the diabetes/weight-loss drug tirzepatide (Mounjaro) in young adults aged 18–26 who have obesity and either Prader-Willi syndrome, hypothalamic obesity, or general obesity. It looks at whether a weekly injection can help with weight management.
Saint Paul, MinnesotaAges 18–26 - NCT06934642RecruitingEarly Phase 1
A study of tirzepatide for fatty liver disease in people with obesity
This trial tests if tirzepatide, a diabetes and weight loss medication, can help improve fatty liver disease in people who are overweight or have obesity. It may offer a new treatment option for managing liver health.
Albuquerque, New MexicoAges 18–75 - NCT06939088RecruitingPhase 2
Tirzepatide for alcohol reduction in schizophrenia
This trial tests if tirzepatide, a once-weekly injection, can help reduce heavy drinking in people who have both schizophrenia and alcohol use disorder. If you struggle with alcohol and have stable schizophrenia, this study may offer a new treatment option.
Aalborg, DenmarkAges 18–70 - NCT06994338RecruitingPhase 2
Tirzepatide for alcohol use disorder
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Los Angeles, CaliforniaAges 21–65 - NCT07065552RecruitingEarly Phase 1
Tirzepatide for weight-linked endometrial cancer
This trial tests if the weight-loss drug tirzepatide can help people with obesity-related endometrial cancer before their hysterectomy. It may improve surgical outcomes and overall health.
Chapel Hill, North CarolinaAges 18 years+ - NCT07096908RecruitingPhase 4
Tirzepatide for weight loss in type 1 diabetes
This study tests a medication called tirzepatide for people with type 1 diabetes who also have overweight or obesity. Tirzepatide may help with weight loss and blood sugar control, and you'll use a continuous glucose monitor throughout the study.
Kuwait City, SharqAges 21 years+ - NCT07245771RecruitingPhase 1/Phase 2
Weight loss study testing a new drug alone or with tirzepatide
This trial tests an experimental drug called RN3161 to see if it helps with weight loss in people with overweight or obesity. It can be taken alone or with another weight-loss medication (tirzepatide).
Melbourne, VictoriaAges 18–65 - NCT07247084RecruitingPhase 4
Tirzepatide for weight loss in adults with obesity
This trial tests if tirzepatide is more effective than standard obesity treatments for adults who have a BMI between 30 and 35 and one weight-related health condition, but do not have diabetes. The goal is to help you lose weight.
AltrinchamAges 18 years+ - NCT07284511RecruitingPhase 2/Phase 3
Tirzepatide for automatic blood sugar control in type 1 diabetes
This trial tests if adding tirzepatide (a once-weekly injection) to an automated insulin pump system (Control-IQ) helps adults with type 1 diabetes better manage their blood sugar. It requires using the Tandem Control-IQ pump and counting carbohydrates.
Montreal, QuebecAges 18 years+ - NCT07326111RecruitingPhase 4
Tirzepatide for PCOS and weight in women
This study tests if tirzepatide (a once-weekly injection) can improve periods and metabolic health in women with PCOS who are overweight. If you have PCOS, irregular cycles, and a BMI of 27 or higher, you might qualify.
BochumAges 18–45 - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07373834Recruiting
Tirzepatide and muscle health in women with obesity
This study tests whether tirzepatide, a medication for weight management, affects muscle health in women with obesity. It may help if you are looking for a treatment that preserves muscle while losing weight.
LjubljanaAges 18–50 - NCT07387796Recruiting
Brain and behavior changes with tirzepatide stop and restart
This study looks at how your brain and behavior change when you stop and then restart the weight loss drug tirzepatide. It will help researchers understand what happens during treatment breaks.
Dallas, TexasAges 18–70
Common questions
- Are there clinical trials studying Tirzepatide?
- Yes. Clin2 currently lists 81 recruiting studies that include Tirzepatide, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Tirzepatide trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Tirzepatide an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Tirzepatide or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.