Clinical trials
Acute Brain Injury clinical trials
Below are recruiting acute brain injury clinical trials, each written for real people, not researchers. We’re tracking 146 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06467708Recruiting
Ear Stimulation for ICU Patients with Traumatic Brain Injury
This study tests a very small electrical device placed on the ear to see if it can help people with traumatic brain injury recover in the intensive care unit (ICU). The device sends gentle pulses to a nerve that may calm inflammation and improve brain function.
Dallas, TexasAges 18 years+ - NCT06836856RecruitingPhase 1/Phase 2
Beta blockers after traumatic brain injury: a study
This trial tests whether giving a beta blocker drug after a moderate or severe traumatic brain injury can improve recovery. It is for patients who have a brain injury but only minor or no other injuries.
ZagazigAges 18–75 - NCT07356167Recruiting
Neurosensory training for mild brain injury symptoms
This study tests a special training program that uses sound and head movements to help people with long-lasting symptoms after a mild brain injury or sudden sensory event. The goal is to see if this 'neurosensory' training can reduce problems like dizziness, headache, and brain fog.
Miami, FloridaAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT06867666Recruiting
Behavioral sleep therapy for insomnia in Navy members with TBI
This study tests a behavioral talk therapy for insomnia (CBT-I) in active duty Sailors who also have a history of traumatic brain injury. You'll learn better sleep habits using an app and coaching, with the goal of improving your sleep and recovery.
San Diego, CaliforniaAges 18 years+ - NCT07119827Recruiting
Personality traits and recovery after brain injury
This study looks at how your personality might affect recovery after a serious brain injury or stroke. You and a family member will answer a short personality questionnaire to see if certain traits are linked to better recovery.
Verona, VRAges 18–80 - NCT02407028RecruitingPhase 2
Hyperbaric oxygen treatment for severe traumatic brain injury
This Phase 2 trial studies whether breathing oxygen in a pressurized chamber can improve outcomes after a severe traumatic brain injury. It is mainly for people with very low consciousness levels soon after injury, with careful safety checks.
San Diego, CaliforniaAges 16–65 - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT06841770RecruitingPhase 1
Testing a delivery device for spinal cord injury treatment
This trial tests a device that delivers a special cell therapy (LCTOPC1) into the spinal cord. It is for people with a recent or chronic spinal cord injury that is severe (no feeling or movement below the injury) or leaves some sensation but no movement.
Downey, CaliforniaAges 18–65 - NCT06245434Recruiting
Circadian rhythms during coma awakening
This study looks at how the body's internal clock (circadian rhythm) changes as people wake up from a coma. Researchers hope to learn more about recovery patterns to improve care for patients with brain injuries.
Bron, LyonAges 17 years+ - NCT02714387Recruiting
Study of serious complications from non-traumatic blood vessel brain problems
This study follows people who have non-injury (non-traumatic) blood-vessel-related problems in the brain to understand serious complications. It may help researchers identify risks and improve care over time.
AngersAges 15 years+ - NCT07345169Recruiting
Immune and inflammation study in ICU patients
This study looks at how your immune system and inflammation affect your recovery in the intensive care unit. Researchers want to understand why some patients do better than others.
ParisAges 18 years+ - NCT07380477Recruiting
Infection risk study for external ventricular drains
This trial looks at whether the fluid from your brain drain (called CSF) can help predict infections. It compares samples taken from different spots on the drain to find better ways to catch infections early.
CopenhagenAges 18 years+ - NCT05745298Recruiting
Electrical and breathing therapy to improve unassisted cough after spinal injury
This study tests whether pairing electrical stimulation with breathing muscle training can help you cough without needing assistance. It’s for people recovering from a spinal cord injury within the last year, and who can safely feel and respond to the electrical stimulation.
Miami, FloridaAges 18 years+ - NCT04054414RecruitingPhase 2
Drug study for improving recovery after acute spinal cord injury
This Phase 2 trial tests sotateltide (PMZ-1620) in people with a recent spinal cord injury. It aims to see whether the drug can improve neurological recovery after injury, especially in certain levels and types of incomplete injuries.
BelagaviAges 18–75 - NCT06940232Recruiting
Blood test study for traumatic brain injury in kids
This study is testing whether a blood test can detect traumatic brain injury (TBI) in children. If successful, it could offer a quicker, less invasive way to diagnose concussions and other head injuries, reducing the need for CT scans or MRIs.
Omaha, NebraskaAges Up to 17 years - NCT07296783Enrolling by invitation
Tracking recovery in older adults with traumatic brain injury
This study observes older adults (65+) who have had a recent head injury to understand how they recover over time. It may help improve care for seniors with brain trauma.
San Francisco, CaliforniaAges 65 years+ - NCT06900101Recruiting
Monitoring study in brain injury intensive care
This study uses a special monitoring system to closely watch patients in the neurologic intensive care unit. It may help doctors better understand and treat brain injuries.
France, BronAges 18–90 - NCT07181174Enrolling by invitation
Early prediction of kidney injury after hemorrhagic stroke
This study looks for early signs of kidney injury in people who have had a spontaneous hemorrhagic stroke. It aims to detect kidney problems quickly so they can be treated sooner.
AswānAges 18 years+ - NCT06032884Recruiting
Comparing two dialysis methods for severe kidney injury in ICU
This trial compares two ways to filter blood (intermittent hemodialysis and continuous renal replacement therapy) for patients in the intensive care unit with severe acute kidney injury. It aims to find which method works better for critically ill patients.
BobignyAges 18 years+ - NCT07696598Recruiting
Brain bleed surgery study in children after head injury
This study looks at how children under 18 do after surgery for a specific type of brain bleed (called an extradural or epidural hematoma) caused by a head injury. The goal is to understand what helps them heal better.
Sohag, Sohag GovernorateAges 1 day–18 years - NCT06577402Recruiting
Study on energy and protein in severe brain injury patients
This study measures how your body uses energy and protein if you are in the ICU with a severe brain injury while on a breathing machine. It can help doctors better understand your recovery needs.
Nanjing, JiangsuAges 18–85 - NCT07404852Recruiting
Vagus nerve stimulation for reducing inflammation after stroke
This trial tests whether a non-invasive device that stimulates the vagus nerve can reduce inflammation and brain injury after a stroke caused by a large blood clot.
St Louis, MissouriAges 18–99 - NCT04867317RecruitingPhase 3
Growth hormone treatment for veterans with mild TBI and deficiency
This Phase 3 study tests whether replacing growth hormone in veterans with mild traumatic brain injury (mTBI) and low adult growth hormone can improve quality of life. If you qualify, you’ll be screened with hormone blood tests and memory/mental health checks before starting treatment.
Birmingham, AlabamaAges 21–55
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Common questions
- Are there clinical trials for acute brain injury?
- Yes. Clin2 currently lists 146 recruiting acute brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.