Clinical trials
Acute Disease clinical trials
Below are recruiting acute disease clinical trials, each written for real people, not researchers. We’re tracking 401 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06786416Recruiting
Monitoring to prevent kidney injury after heart surgery
This trial is testing a new monitoring system that tracks blood flow and other vital signs during heart surgery to help prevent kidney damage afterward.
San Donato Milanese, MilanoAges 18 years+ - NCT06414928Recruiting
Predicting Outcomes in Heart Failure Patients
This study is looking at people with heart failure who come to the emergency room at NICVD in Karachi. The researchers want to build a simple tool to predict how heart failure patients will do over the next 30 days, which may help guide better care.
Karachi, SindhAges 18 years+ - NCT02872987Recruiting
Adult blood cancer registry study with stored samples
This study enrolls adults with certain blood cancers to better understand diagnosis, treatment choices, and outcomes. You may also be asked to provide or have tissue/blood samples saved so researchers can study what’s going on in the disease.
GrazAges 18 years+ - NCT06936566RecruitingPhase 2
Ruxolitinib for graft-versus-host disease after transplant
This trial tests a drug called ruxolitinib for treating acute graft-versus-host disease (aGVHD), a common complication after a stem cell transplant. It may help control the immune reaction without using high doses of steroids.
Duarte, CaliforniaAges 18 years+ - NCT06343792RecruitingPhase 2
Testing RLS-0071 for steroid-resistant acute graft-versus-host disease
This trial tests a new drug, RLS-0071, for people who are hospitalized with acute graft-versus-host disease that hasn't improved with steroids. It aims to see if the drug is safe and can help control the condition.
Duarte, CaliforniaAges 12 years+ - NCT06750133RecruitingPhase 1
CNK-UT cell therapy for steroid-resistant graft-versus-host disease
This trial tests a new cell therapy called CNK-UT for people with severe graft-versus-host disease (aGVHD) that hasn't improved with steroid treatment after a stem cell transplant. The goal is to see if it can help control the immune reaction.
Fuzhou, FujianAges 14–70 - NCT06321198Recruiting
Modified stem cells for severe graft-versus-host disease
This trial tests a new type of stem cell therapy (iMSC) for people with steroid-resistant acute graft-versus-host disease (aGVHD), a serious complication after a stem cell transplant. The goal is to see if it's safe and might help control the disease.
Hefei, AnhuiAges 4–70 - NCT07070674RecruitingPhase 1
Study of AC-003 for steroid-resistant graft-versus-host disease
This trial tests an experimental capsule (AC-003) for people with graft-versus-host disease (aGVHD) after a stem cell transplant, whose aGVHD did not get better with steroids. The goal is to see if it can help control the condition.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06708507Recruiting
Immune cells in graft-versus-host disease
This study looks at special immune cells in the body that may be involved in graft-versus-host disease (GVHD), a complication after a stem cell transplant. The goal is to better understand these cells to improve future treatments for GVHD.
Guangzhou, Other (Non U.s.)Ages 18–65 - NCT07392970RecruitingPhase 2
Motixafortide to improve AML treatment response after chemo
This trial tests if adding motixafortide can help find and eliminate leftover leukemia cells in people with AML who are in remission after initial chemotherapy. The goal is to make remission deeper and more durable.
St Louis, MissouriAges 18 years+ - NCT04748237Recruiting
CT heart scan for intermediate-risk chest pain
This study tests whether a special heart CT scan can help evaluate the cause of chest pain in people at intermediate risk for blocked heart arteries. It may help doctors decide what to do next after an emergency room visit.
StockholmAges 18 years+ - NCT05149196Recruiting
Goal-directed fluid and blood pressure plan after kidney surgery
This trial tests a carefully tailored plan for managing blood pressure and fluid during and after kidney removal surgery, to help reduce kidney injury after surgery. It may be especially helpful if you’re having one kidney removed for cancer and your baseline heart/kidney risk is not too high.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05703919RecruitingPhase 4
Compare standard vs targeted oxygen for COPD flare-ups
This trial tests whether giving oxygen in a standard way or a more targeted way helps people who are having a COPD flare-up before they reach the hospital. It may help reduce oxygen-related harms while still treating low oxygen during emergency care.
Aarhus NAges 40 years+ - NCT06038630RecruitingPhase 2
Xenon gas MRI study for lung and heart health
This study uses a special MRI scan (Xenon gas imaging) to look at how well your lungs and heart are working. It is for people with certain lung conditions, those getting blood transfusions or phlebotomy, or healthy volunteers.
Durham, North CarolinaAges 18 years+ - NCT06331416Recruiting
Home monitoring after COPD flare-up
This trial tests if people with COPD can use a home monitoring system after a flare-up to help doctors track their recovery. It aims to reduce hospital visits and improve care.
TriesteAges 18–90 - NCT06451198RecruitingPhase 4
Indobufen vs aspirin after stent in older heart patients
This trial tests whether a blood thinner called indobufen works as well as aspirin for older people (65+) who have had a heart attack or unstable angina, received a drug-eluting stent, and are already taking two blood thinners. The goal is to find a safer or better option for long-term prevention.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT06497153Recruiting
Lung ultrasound for children with sickle cell disease
This study tests whether using lung ultrasound can help doctors quickly spot and treat acute chest syndrome in children with sickle cell disease. It may lead to faster, safer care for kids in the intensive care unit.
ParisAges 1 month–17 years - NCT07291388Recruiting
Retrolaminar block for lumbar fusion with multimodal pain control
This study tests whether adding a retrolaminar block (a type of back injection) to standard pain medicines helps reduce pain after lumbar spine fusion surgery. It may help you recover with less need for strong painkillers.
Santiago, Santiago MetropolitanAges 18–75 - NCT06745141Recruiting
Gum disease treatment after a heart attack
This trial tests whether treating severe gum disease can improve recovery after a heart attack (STEMI). If you recently had a heart attack and also have serious gum problems, you may be able to join and receive periodontal care.
Shanghai, Shanghai MunicipalityAges 30 years+ - NCT06885476Recruiting
NK cell infusion for AML patients with minimal cancer left
This trial tests if giving special immune cells from a donor can clear leftover leukemia cells in patients who are in remission but still have traces of cancer after chemotherapy.
Bologna, BOAges 18 years+ - NCT06886074RecruitingPhase 2
Short blinatumomab to clear leftover B-ALL cells
This trial tests if a shorter course of blinatumomab can remove minimal residual disease (MRD) — tiny traces of leukemia not seen under a microscope — in people with B-cell acute lymphoblastic leukemia after initial treatment.
Monterrey, Nuevo LeónAges 16–60 - NCT07184853Recruiting
Ruxolitinib with etanercept vs ruxolitinib for severe GVHD
This trial tests whether adding etanercept to ruxolitinib works better than ruxolitinib alone for severe graft-versus-host disease (GVHD) that has not responded to steroids. GVHD is a common complication after a stem cell transplant where donor cells attack the patient's body.
Hangzhou, ZhejiangAges 12–70 - NCT01277419Recruiting
Study of new cases of several spine, joint, and eye diseases
This study enrolls people who have recently been diagnosed with certain inflammatory conditions affecting the spine, joints, or the eye. Researchers are looking to better understand how these illnesses start and how they may be linked, which could help guide future care.
BerlinAges Any age - NCT05161078Enrolling by invitation
Studies CARPEDIEM care for newborns and babies in participating hospitals
This trial looks at how to improve outcomes for newborns and infants who receive CARPEDIEM as part of routine hospital care. It aims to see whether an interdisciplinary team approach can make treatment safer and more effective.
Palo Alto, CaliforniaAges Any age
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Common questions
- Are there clinical trials for acute disease?
- Yes. Clin2 currently lists 401 recruiting acute disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.