Clinical trials
Acute Disease clinical trials
Below are recruiting acute disease clinical trials, each written for real people, not researchers. We’re tracking 401 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07125352Recruiting
NLR blood test for COPD flare-ups
This study looks at whether the neutrophil-to-lymphocyte ratio (NLR) in your blood can help doctors understand how serious a COPD flare-up is. You may join if you are 18 or older and admitted to the hospital with a COPD exacerbation.
Cairo, AbbasyeaAges 18 years+ - NCT06801262Recruiting
New Blood Test to Detect Kidney Transplant Rejection
This trial is testing a new blood test (called TreaT-Assay) to help diagnose acute rejection after a kidney transplant. The goal is to catch rejection earlier and more accurately, so you can get the right treatment faster.
BolognaAges 18 years+ - NCT06712004RecruitingPhase 2
Testing a new stroke drug: different doses for people who cannot get standard care
This trial tests a new medication (bevifibatide) to see which dose works best for people having an ischemic stroke who cannot get standard treatments like clot-busting drugs or a procedure to remove the clot. It aims to improve recovery by stopping clots from getting worse.
Guangzhou, GuangdongAges 18–80 - NCT06892210RecruitingPhase 4
Steroid comparison for COPD flare-ups
This trial compares two common steroids, hydrocortisone and prednisolone, to see which works better for treating COPD flare-ups. It may help you recover faster from a sudden worsening of your breathing.
Rønne, BornholmAges 40 years+ - NCT04427826RecruitingPhase 1/Phase 2
Morphine to prevent early NIV failure in COPD flare-ups
This trial studies whether morphine can help people with a COPD flare-up avoid “non-invasive ventilation” (breathing support through a mask) failing early. The goal is to reduce how often people need escalation of care soon after starting NIV.
Grenoble, Isère, Auvergne-Rhône-AlpesAges 18 years+ - NCT05788679RecruitingPhase 2
Use a patient’s genetic test to guide treatment after transplant
This study looks at a personalized lab test to detect small amounts of disease after a stem cell transplant and then decide what treatment comes next. It may help some people with certain bone-marrow diseases stay in remission while avoiding unnecessary treatment.
StockholmAges 18 years+ - NCT04890483Recruiting
Brain stimulation to ease pain and fatigue after COVID
This study tests whether a noninvasive brain stimulation treatment can reduce fatigue and body pains after COVID in people with autoimmune diseases. It may help symptoms by changing brain activity without surgery.
São PauloAges 18–80 - NCT06428188RecruitingPhase 1/Phase 2
CAR-T cells targeting BCMA/CD19 for autoimmune diseases
This trial tests a new treatment called CAR-T cells that target two proteins (BCMA and CD19) on immune cells. It is for people with certain autoimmune diseases that have not improved with standard treatments.
Beijing, Beijing MunicipalityAges 21–90 - NCT06144606RecruitingPhase 2
KTE-X19 CAR T for MRD+ B-ALL
This trial tests a CAR T-cell therapy called KTE-X19 for people with B-cell ALL that is in remission but still has trace disease (MRD-positive). The goal is to see if this treatment can eliminate the remaining cancer cells and prevent relapse.
Tampa, FloridaAges 18 years+ - NCT01252485Recruiting
Biology and outcome registry for acute leukemia patients
This is a research registry that collects information and lab/blood sample data to better understand what acute leukemia looks like biologically and how patients do over time. It may help future treatment decisions, but it does not describe testing a new drug.
GrazAges 18 years+ - NCT05317494Recruiting
Test of venetoclax for AML when intensive chemo isn’t possible
This study looks at how a person’s leukemia “disease state” changes over time for adults with acute myeloid leukemia (AML) who cannot receive the strongest (“intensive”) chemotherapy. It tests using oral venetoclax as a first treatment option, which may help control the disease for people ineligible for intensive chemo.
Pátrai, AchaiaAges 18 years+ - NCT05587049Recruiting
Testing an oral medicine plus azacitidine to improve AML disease
This study looks at how a standard AML treatment plan affects a person’s disease status over time. It focuses on newly diagnosed adults who cannot safely get intensive chemotherapy, using oral venetoclax plus azacitidine.
Medellín, AntioquiaAges 18 years+ - NCT05772559Recruiting
Study of AML genes and drug response in young patients
This trial looks at how childhood, teen, and young adult acute myeloid leukemia (AML) changes at the genetic level and how cells respond to multiple drugs. It may help doctors understand which treatments work best and how leukemia interacts with supportive cells in the bone marrow.
AmiensAges Up to 25 years - NCT06861478RecruitingPhase 2
PPIs for bleeding varices in liver disease
This trial tests whether proton pump inhibitors (PPIs) can help people with cirrhosis who are hospitalized for variceal bleeding. It looks at whether PPIs reduce complications during the hospital stay.
Monterrey, Nuevo LeónAges 18 years+ - NCT06898762Recruiting
National study on inflammatory heart disease for patients with symptoms
This study is creating a national registry to learn more about inflammatory myocardial disease (inflammation of the heart muscle). If you have symptoms like chest pain, shortness of breath, palpitations, or certain test results, you may be eligible to join and help advance research.
Murcia, MurciaAges 18 years+ - NCT04024761RecruitingPhase 1
NK cell therapy for leukemia relapse after transplant
This Phase 1 study tests whether an infusion of special immune cells (NK cells) from a donor can help control leukemia or related blood cancers that come back or do not fully go away after a stem cell transplant. It also uses short chemotherapy to “make space” for the NK cells to work, and IL-2 to help them function.
Boston, MassachusettsAges 12 years+ - NCT05586282Recruiting
Study proteins that may worsen fluid leaks in shock
This trial studies specific body proteins to understand why fluid can leak from blood vessels during dangerous shock after infection or heart problems. If you (or your representative) qualify, your team will collect information and possibly samples to see whether these proteins relate to recovery and treatment response.
ParisAges 18 years+ - NCT06173947Recruiting
SSM Score for Liver Injury in Chronic Liver Disease
This study looks at how well a simple score (called SSM) can predict recovery in people with chronic liver disease who suddenly get a liver injury with jaundice. It may help your doctors understand how serious your condition is.
Guangzhou, GuangdongAges 18–80 - NCT07687706RecruitingPhase 3
Tegoprazan to prevent stomach problems after stroke
This study tests a stomach-protecting medicine called tegoprazan for people who have had a stroke and are starting antiplatelet therapy. It aims to prevent stomach complications like ulcers or bleeding.
Busan, BusanAges 19 years+ - NCT07259174Recruiting
Ultrasound for diaphragm in COPD flare-ups
This study uses ultrasound to measure how well your diaphragm muscle works during a COPD flare-up. The goal is to see if this measurement can help predict how you will recover.
Zwolle, OverijsselAges 18 years+ - NCT07364617RecruitingPhase 2
Fecal transplant for steroid-resistant gut GVHD
This study tests if a fecal transplant (transferring healthy bacteria from a donor's stool into your gut) can help people with severe gut graft-versus-host disease that hasn't responded to steroids. It's for patients who have had a stem cell transplant and now have ongoing, severe gut symptoms.
TaoyuanAges Any age - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT07643610Recruiting
Heart Failure Crisis Registry Study
This registry collects information from patients admitted to the hospital with cardiogenic shock—a serious condition where the heart cannot pump enough blood to the body. Doctors will gather data to better understand what happens to these patients and how to improve their care.
Basel, Canton of Basel-CityAges 18 years+ - NCT06817577RecruitingPhase 1
Study of NG004 for recent spinal cord injury
This trial tests a new medicine called NG004 for people who have recently had a spinal cord injury in the neck area (cervical spine) and still have some movement and feeling. The goal is to see if it can help improve recovery.
BayreuthAges 18–70
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Common questions
- Are there clinical trials for acute disease?
- Yes. Clin2 currently lists 401 recruiting acute disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.