Clinical trials
Acute Heart Failure clinical trials
Below are recruiting acute heart failure clinical trials, each written for real people, not researchers. We’re tracking 418 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04982419RecruitingPhase 2/Phase 3
Remote arm treatment to protect heart and kidneys in heart failure
This trial tests whether a simple “arm cuff” treatment done before a heart artery procedure can help protect the kidneys and the heart in people with congestive heart failure. If it works, it may lower the chance of kidney injury around the time of the scan/stent procedure.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05525663Recruiting
Rehab for older adults after heart failure with strong pumping
This trial studies whether a physical rehabilitation program helps older adults recover and function better after a recent hospital stay for heart failure when the heart’s pumping strength is preserved. It may help you regain walking ability and daily independence after your episode.
Winston-Salem, North CarolinaAges 60 years+ - NCT05392764RecruitingPhase 3
SGLT2 medicine for high-risk people after sudden worsening heart failure
This Phase 3 trial tests whether starting an SGLT2 inhibitor early in the hospital can improve outcomes for people at high risk after acute (sudden) heart failure. If you qualify, you would be randomized to receive the study medicine or standard care, started within 12 hours of admission.
Anjo, Aichi-kenAges 20 years+ - NCT05276219RecruitingPhase 4
Vasodilators or diuretics for acute heart failure
This trial compares two treatments for sudden heart failure symptoms like severe shortness of breath. It aims to see whether opening blood vessels or using a water pill works better to relieve congestion and improve breathing.
Copenhagen, CopenhagenAges 18 years+ - NCT05255172Enrolling by invitation
Exercise program for heart failure with preserved or reduced pumping
This trial tests whether a structured exercise program can help people with heart failure. It focuses on people who are currently not very active, aiming to improve symptoms and heart/fitness measures safely.
LundAges 50–90 - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT03999138Recruiting
MRI study of lung fluid changes in acute heart failure
This study uses MRI scans to measure lung fluid (pulmonary edema) in people hospitalized for acute heart failure. It aims to see how well the lung fluid responds to standard treatments like water pills (diuretics) given in the first couple of days.
Edmonton, AlbertaAges 18 years+ - NCT04000061Recruiting
Tracking heart failure and heart attack progress in hospital
This study looks at how heart problems progress while you’re in the hospital, using your medical information (clinical data). It may help doctors better predict outcomes and improve care for people with heart attacks and heart failure.
BaselAges 18 years+ - NCT03586336Recruiting
Remote lung fluid monitoring to guide heart failure treatment
This study tests a wearable vest that measures fluid in your lungs to help doctors adjust water-pill treatments for heart failure. It aims to reduce hospital stay and improve recovery.
San Francisco, CaliforniaAges 18 years+ - NCT03103932Recruiting
Blood test–guided discharge for people hospitalized with heart failure
This trial checks whether using a blood test (a “biomarker”) can help doctors decide when it’s safe to send people home after a hospital stay for worsening heart failure. It may help reduce avoidable readmissions while keeping you safe.
Ottawa, OntarioAges 18 years+ - NCT02898181Recruiting
Ear stimulation for heart failure in hospital
This study tests a gentle electrical stimulation on the ear to see if it can help people with heart failure feel better while they are in the hospital. It might help reduce symptoms and improve heart function.
Oklahoma City, OklahomaAges 18–80 - NCT02368041Recruiting
Near-infrared scan test in children with heart failure
This study tests whether a near-infrared “light scan” on the hand can help doctors in children with heart failure who are stable on their usual medications. It may give additional information about blood flow and circulation in the body without using invasive procedures.
Gainesville, FloridaAges Up to 25 years - NCT00762008Recruiting
Test blood markers to understand progression to heart failure
This study looks at blood “markers” (substances in the blood) to help explain how some people move from early heart strain to full heart failure. You may be enrolled if you have stable or worsening heart failure symptoms, or you may qualify as a healthy control for comparison.
Farmington, ConnecticutAges 18 years+ - NCT07575672RecruitingPhase 3
Finerenone after heart valve replacement
This study tests if the drug finerenone helps people with heart failure who had a heart valve replacement (TAVI) for severe aortic stenosis. The goal is to see if it improves heart function and outcomes.
Bengbu, AnhuiAges 65 years+ - NCT07825363Recruiting
Early warning system for heart failure or heart attack patients
This study tests a sensor that monitors oxygen levels in body tissues to help doctors spot when your heart is not pumping enough blood early. The goal is to catch problems sooner so you can get faster treatment.
Weston, FloridaAges 18 years+ - NCT07704424Recruiting
Testing a heart pump for severe right heart failure
This trial is evaluating a new temporary heart pump called CorVad for people who develop severe right heart failure shortly after heart surgery, a heart attack, or a heart transplant. The pump is designed to help the right side of the heart pump blood when medications are not enough.
Hefei, AnhuiAges 18 years+ - NCT07657650Recruiting
Imaging test for heart failure patients before revascularization
This trial uses a special imaging scan to see if heart muscle has damage from blocked arteries. It helps doctors decide if a procedure to open blocked arteries might improve your heart function.
BeijingAges 18 years+ - NCT07552142Recruiting
Heart Failure Check-In: Using Questionnaires to Spot Early Warning Signs
This study asks heart failure patients who recently were hospitalized to answer regular questionnaires about how they're feeling. Researchers want to see if these questions can detect when heart failure is getting worse before a patient needs emergency care.
Moscow, Non-US/Non-CanadianAges 18 years+ - NCT07554638RecruitingPhase 4
Incretin drugs for heart failure with obesity
This trial tests whether incretin-based diabetes medications (like GLP-1 drugs) can help people with a specific type of heart failure called HFpEF that is linked to obesity. The goal is to see if these drugs improve heart function and symptoms.
New York, New YorkAges 40 years+ - NCT07506499Recruiting
Cardiac Rehab for Hospitalized Heart Failure Patients
This study tests whether a cardiac rehabilitation program (a supervised exercise and education plan) helps people recovering in the hospital from severe heart failure. It is for those aged 45–65 whose heart pumps less than 40% of its normal amount.
Banī Suwayf, Beni-Suef GovernorateAges 45–65 - NCT07490054RecruitingPhase 1
Fecal transplant for chronic heart failure
This trial tests whether transferring healthy gut bacteria (fecal microbiota transplant) can help people with chronic heart failure feel better and improve their heart function.
New York, New YorkAges 18 years+ - NCT07402239Recruiting
Heart failure therapy and monitoring device study
This trial tests a device that treats and monitors heart failure. It may help people with chronic heart failure and reduced heart function who still have symptoms despite standard treatments.
Fuzhou, FujianAges 18 years+ - NCT07325942Recruiting
Low vs high volume high-intensity interval training for heart failure
This study compares two different types of high-intensity interval exercise programs (one shorter, one longer) in people with chronic heart failure. It aims to see which program improves heart health and daily function more.
Cairo, Giza GovernorateAges 18 years+ - NCT07243769Recruiting
Comparing exercise types for heart rehab
This trial compares core, aerobic, and combined exercise in patients doing phase II cardiac rehab. It aims to find which type works best for heart recovery.
TaipeiAges 18 years+
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Common questions
- Are there clinical trials for acute heart failure?
- Yes. Clin2 currently lists 418 recruiting acute heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.