Clinical trials
Adaptation clinical trials
Below are recruiting adaptation clinical trials, each written for real people, not researchers. We’re tracking 645 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03371407Recruiting
Study brain movement training in people with Parkinson’s
This study looks at how people with Parkinson’s adapt their movements and how their brain sensorimotor system works. It may help researchers improve understanding of Parkinson’s and refine movement-focused therapies.
MarseilleAges 18 years+ - NCT03215719RecruitingPhase 2
De-escalating treatment for HPV-positive throat cancer with low-risk signals
This Phase 2 trial tests whether people with HPV-positive oropharyngeal (throat) cancer who look “lower risk” can safely receive less intensive treatment. It uses HPV blood test results and cancer staging scans to guide whether treatment can be de-escalated.
New York, New YorkAges 18 years+ - NCT07676240Recruiting
Coaching program for fathers with young kids in home visiting
This trial tests a coaching program for fathers with children ages 12 to 36 months who are enrolled in Akin services. The program is designed to support fathers and their young children through home visits.
Seattle, WashingtonAges 1 year+ - NCT03932903Recruiting
Phone coaching to help teens stay on leukemia medicine
This trial tests a mobile (phone) health program to help adolescents and young adults with leukemia take their oral chemotherapy medicine consistently. It may help if staying on daily pills is hard during the maintenance phase of treatment.
Chicago, IllinoisAges 14 years+ - NCT06983873Recruiting
Better cervical spine care for stable trauma patients
This trial tests a new way to manage neck injuries in conscious, stable patients during emergency care before reaching the hospital. It aims to see if this approach improves recovery and care after the injury.
AmiensAges 18–65 - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+ - NCT07398690Recruiting
MRI-guided approach for prostate cancer diagnosis
This trial tests if using MRI and a blood test called PHI can help decide who needs a prostate biopsy. It aims to avoid unnecessary biopsies while still catching cancer early.
SeoulAges 20 years+ - NCT07399626RecruitingPhase 1/Phase 2
Validation of a hypomania risk scale in Romanian
This study adapts and validates a short questionnaire (HPS-6) to measure traits linked to hypomania in Romanian speakers. Participation involves completing surveys, which may help identify early signs of mood changes.
Cluj-NapocaAges 18–50 - NCT07413315Recruiting
Kidney rehab program for dialysis patients after hospital stay
This study tests a special exercise and education program for people on daily hemodialysis (a type of kidney treatment) who have recently been in the hospital. The goal is to see if this program helps you recover and feel better.
BrusselsAges 18 years+ - NCT07419087Recruiting
French trunk impairment scale adaptation and validation study
This study aims to adapt and validate a French version of the Trunk Impairment Scale, a tool that measures how well stroke survivors can control their trunk (core body) movements. Participating will help researchers improve stroke recovery assessments.
Ploemeur, Please Choose...Ages 18–85 - NCT07425054RecruitingPhase 2
Chemoradiation with or without immunotherapy for anal cancer
This trial tests whether adding an immunotherapy drug (retifanlimab) to standard chemoradiation improves outcomes for people with locally advanced anal cancer. The treatment is adjusted based on HPV DNA levels in your blood.
Cleveland, OhioAges 18 years+ - NCT07448324RecruitingPhase 2
Orelabrutinib plus rituximab with or without lenalidomide for untreated MZL
This trial tests a combination of targeted drugs for people with a type of lymphoma called marginal zone lymphoma (MZL) that has not been treated before. The drugs attack cancer cells in different ways, and the treatment plan may adjust based on how you respond.
Nanjing, JiangsuAges 18 years+ - NCT07449091Recruiting
HBV undetectable equals untransmissible study
This study checks if having undetectable hepatitis B virus (HBV) means you cannot pass it to others. It tests this idea in people with chronic HBV who are on treatment, those not on treatment, and healthy controls.
New York, New YorkAges 18–65 - NCT07453264Recruiting
Warming care at birth for newborns
This trial tests a special care bundle to keep babies warm right after birth. It may help with temperature, heart rate, and make breastfeeding easier.
Kocaeli, darıcaAges 2 hours–2 hours - NCT07459101Recruiting
MR-guided radiation therapy for high-grade brain tumors
This study tests a new way to deliver radiation therapy for a type of aggressive brain tumor called glioblastoma or grade 4 astrocytoma. Patients get MRI scans during each treatment so the radiation beam can be adjusted precisely, aiming to improve outcomes.
Toronto, OntarioAges 18 years+ - NCT07459673RecruitingPhase 2
HER2-positive breast cancer trial using ctDNA to guide treatment
This trial tests a personalized treatment plan for HER2-positive breast cancer that has spread. It uses a blood test to track cancer DNA and adjust therapy, including treatments that may help prevent cancer from reaching the brain. The goal is to achieve long-term remission.
Basking Ridge, New JerseyAges 18 years+ - NCT07464912RecruitingPhase 3
Testing TDI01 for idiopathic pulmonary fibrosis
This trial tests a new drug called TDI01 to see if it helps people with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring. You may qualify if you have a confirmed IPF diagnosis and your lung function is stable enough.
Beijing, Beijing MunicipalityAges 40–80 - NCT07477561Recruiting
Healthy aging program for older adults in Singapore
This trial tests a program to help older adults stay independent and prevent frailty. It is based on the World Health Organization's ICOPE approach and is designed for Singaporeans and permanent residents aged 60 and older.
SingaporeAges 60 years+ - NCT07480213RecruitingPhase 1/Phase 2
CAR-NK cell therapy for relapsed small cell lung cancer
This trial tests a new type of immunotherapy called dual-target CAR-NK cells for people with small cell lung cancer that has returned or not responded to treatment. The treatment uses your own immune cells, modified in a lab, to better recognize and attack cancer cells.
Shenzhen, GuangdongAges 18–75 - NCT05716893RecruitingPhase 2
Aerobic exercise program for people getting breast cancer treatment
This Phase 2 study tests whether a supervised aerobic (cardio) training program can improve health and exercise capacity for people receiving treatment for primary breast cancer. You may join if you currently do very little moderate-to-vigorous exercise and can safely complete a special treadmill test that measures breathing and heart response.
Basking Ridge, New JerseyAges 18 years+ - NCT07495059Recruiting
HIV prevention and care study for transgender women
This trial tests an adapted approach to improve HIV prevention and care for transgender women in Ho Chi Minh City. It aims to help participants stay healthy and access services.
Ho Chi Minh CityAges 16 years+ - NCT07498296Recruiting
Adapting a home program and sleep tracking for Parkinson's
This trial tests a program to help people with Parkinson's disease exercise at home and improve sleep. It uses online coaching and a video device to see if it makes daily tasks easier.
Aurora, ColoradoAges 18 years+ - NCT07500545Recruiting
Heat health study for Lake County adults
This study tests a program to help people stay safe during extreme heat. If you live in Lake County, you may be able to join and learn ways to cope with heat.
Lakeport, CaliforniaAges 18 years+ - NCT07505355Recruiting
Walking and foot tap test in multiple sclerosis
This study tests two simple walking and foot-tapping exercises to see how well they measure balance and mobility in people with multiple sclerosis. It aims to help doctors better track walking problems in MS.
DiepenbeekAges 18–65
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Common questions
- Are there clinical trials for adaptation?
- Yes. Clin2 currently lists 645 recruiting adaptation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adaptation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adaptation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.