Clinical trials
Advanced or Metastatic Breast Cancer clinical trials
Below are recruiting advanced or metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 6,206 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06843967RecruitingPhase 1/Phase 2
Mirdametinib and palbociclib for liposarcoma
This trial tests two targeted drugs – mirdametinib and palbociclib – taken as pills for people with a specific aggressive type of liposarcoma (dedifferentiated liposarcoma) that has spread or can't be removed. The goal is to see if this combination can shrink or slow the tumor.
Basking Ridge, New JerseyAges 18 years+ - NCT06844136Recruiting
ChemoINTEL test study for ovarian cancer
This study is testing a new lab test (called ChemoINTEL) that looks at how your cancer cells respond to chemotherapy drugs used for ovarian cancer. The goal is to see if the test can predict how well the treatment will work for you.
Liverpool, MerseysideAges 18 years+ - NCT06846762Recruiting
DNA/RNA co-testing for advanced lung cancer that has stopped responding to first treatment
This study is for people with advanced non-small cell lung cancer whose tumors do not have certain genetic changes (called driver mutations) and whose first treatment did not work well or caused bad side effects within 6 months. The researchers want to use a special test (DNA/RNA-NGS) to look for hidden genetic alterations that might explain why the cancer didn't respond.
Shanghai, Shanghai MunicipalityAges Any age - NCT06854393RecruitingPhase 2
Lacripep Eye Drops for Faster Healing After PRK
This study is testing a new eye drop called Lacripep to see if it helps heal the cornea (the clear front part of the eye) faster after PRK laser vision correction. It is for active-duty military members and their families who are already planning to have PRK surgery.
Fort Belvoir, VirginiaAges 21–55 - NCT06854679Recruiting
MRI-guided radiation for rectal cancer
This trial tests a new way of giving radiation therapy for rectal cancer, using MRI scans to aim the radiation more precisely. It's for people who need chemotherapy and radiation before surgery, and it aims to make treatment more effective while reducing side effects.
Sutton, SurreyAges 18 years+ - NCT06855186Recruiting
Rehabilitation for concussion based on your symptoms
This study tests a symptom-focused rehabilitation program for people who had a mild traumatic brain injury (concussion) at least 3 months ago. It aims to help with ongoing cognitive complaints like memory or concentration problems.
Wahiawa, HawaiiAges 18–64 - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Birmingham, AlabamaAges 40–60 - NCT06857175RecruitingPhase 3
Comparing a new drug to standard chemo for advanced bladder cancer
This trial tests a new drug called BL-B01D1 against standard chemotherapy for people with advanced bladder cancer that has stopped responding to platinum chemo and immunotherapy. The goal is to see if the new drug works better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06860490RecruitingPhase 2
Liver cancer trial: HAIC plus immunotherapy and anti-angiogenesis
This trial tests a combination of liver-directed chemotherapy (HAIC), an immunotherapy drug (sintilimab), and a drug that blocks blood vessel growth (bevacizumab biosimilar) for advanced liver cancer that hasn't been treated with systemic therapy before. The goal is to see if this triple therapy can shrink or control the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06860932Recruiting
Palliative care program for MS and related disorders
This study tests a palliative care program designed to help people with long-term neurological conditions like MS, NMOSD, or anti-MOG disease. You will learn about managing symptoms and planning care, and the study will measure how this affects your knowledge and attitudes.
New York, New YorkAges 18–65 - NCT06863805Recruiting
Blood markers in advanced thyroid cancer
This study is looking at how certain substances in the blood (called biomarkers) can help doctors understand and treat advanced thyroid cancer. It is for people who are about to start their first systemic therapy (medication that works throughout the body) for advanced thyroid cancer, and who have already had a genetic test on their tumor.
BolognaAges 18 years+ - NCT06868797Recruiting
Dapagliflozin for advanced heart failure patients waiting for transplant
This study tests whether dapagliflozin (a medicine already approved for other heart conditions) can help protect kidney and heart function in people with very advanced heart failure who are waiting for a heart transplant. If you qualify, you'll help researchers learn if this drug offers extra benefits beyond standard care.
BronAges 18 years+ - NCT06873815RecruitingPhase 2
Using a dye to help see cancer during vulvectomy for Paget's disease
This trial tests whether a fluorescent dye called fluorescein sodium can help surgeons see the edges of extramammary Paget's disease more clearly during vulvectomy, so they can remove all the cancer while sparing as much healthy tissue as possible.
Basking Ridge, New JerseyAges 18 years+ - NCT06876753Recruiting
Advanced liver cancer: TACE with immunotherapy and anti-angiogenesis
This trial is for people with advanced liver cancer (HCC) that has spread outside the liver. It tests whether combining a TACE procedure with immunotherapy and anti-angiogenesis drugs can improve outcomes. You must not have had prior systemic therapy and must have received TACE in a specific time window around starting these drugs.
Nanjing, JiangsuAges 18–80 - NCT06878222RecruitingPhase 2
Testing an immunotherapy combo before surgery for cervical cancer
This trial tests whether combining two immunotherapy drugs (iparomlimab and tuvonralimab) with standard chemotherapy (paclitaxel and cisplatin) before surgery can help shrink cervical cancer. It is for people with certain stages of cervical cancer who are candidates for surgery, including those who want to preserve their fertility.
ShanghaiAges 18–75 - NCT06884618RecruitingPhase 1
Study of RO7673396 for advanced solid tumors with RAS mutations
This trial tests a new drug, RO7673396, for people with advanced solid tumors that have a RAS mutation. The goal is to see if the drug is safe and works against the cancer.
Duarte, CaliforniaAges 18 years+ - NCT06885554Recruiting
Military Adjustment Disorder: Tracking Recovery Over Time
This study follows active duty military members recently diagnosed with adjustment disorder to understand how the condition changes over time. Participants will use a smartphone app to track symptoms and complete questionnaires, helping to improve care for service members.
San Diego, CaliforniaAges 18–64 - NCT06885814RecruitingPhase 2
Adebrelimab with chemoradiation for advanced esophageal cancer
This trial tests a drug called adebrelimab (an immunotherapy) combined with chemotherapy and radiation for people with advanced esophageal cancer that cannot be removed by surgery or has come back after surgery. It aims to see if the combination is safe and effective.
Guangzhou, GuangdongAges 18–75 - NCT06887335Recruiting
Deep sedation with early breathing tube for advanced bronchoscopy
This trial tests whether putting a breathing tube in before sedation (instead of waiting until later) makes advanced bronchoscopy safer and more comfortable. If you need a bronchoscopy for diagnosis or treatment, this study may be an option for you.
YangsanAges 19–90 - NCT06888310Recruiting
Better liver test for metabolic fatty liver disease
This study tests a better way to check for advanced liver scarring (cirrhosis) in people with fatty liver disease. It might help you avoid unnecessary procedures if you have metabolic liver disease and are at risk of serious liver problems.
RomaAges 18 years+ - NCT06891560RecruitingPhase 2
Enfortumab vedotin for adenoid cystic carcinoma
This trial tests a drug called enfortumab vedotin for people with adenoid cystic carcinoma (ACC) that has spread or come back. The drug is given through a vein and may help shrink tumors or slow the cancer.
Basking Ridge, New JerseyAges 18 years+ - NCT06893783RecruitingPhase 2
Tarlatamab for advanced extrapulmonary neuroendocrine carcinoma
This study tests a drug called tarlatamab for people with a rare cancer called extrapulmonary neuroendocrine carcinoma that has grown or returned after standard chemotherapy. The goal is to see if tarlatamab can help shrink tumors and improve outcomes.
SeoulAges 19 years+ - NCT06893887Recruiting
Personalized treatment for advanced liver cancer
This trial tests a personalized treatment plan for people whose advanced liver cancer (hepatocellular carcinoma) has progressed after initial targeted and immune therapy. It aims to find a next-step option tailored to your specific situation.
Nanjing, JiangsuAges 18 years+ - NCT06894303Recruiting
Remote programming for cochlear implants in routine follow-up
This study tests if cochlear implants can be adjusted remotely (without visiting the clinic) during regular follow-ups. If you have a compatible implant and sound processor, you may be able to take part from home.
ParisAges 18 years+
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Common questions
- Are there clinical trials for advanced or metastatic breast cancer?
- Yes. Clin2 currently lists 6,206 recruiting advanced or metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.