Clinical trials
Ankle Instability clinical trials
Below are recruiting ankle instability clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06527287Recruiting
Ankle training for stability in active adults
This trial tests a new ankle training program for people with chronic ankle instability who are physically active. It aims to improve ankle function and reduce the risk of future injuries.
Lexington, KentuckyAges 18–44 - NCT07708584Recruiting
Brostrom repair with BioBrace for chronic ankle instability
This trial tests whether adding a BioBrace scaffold to standard Brostrom surgery improves outcomes for people with chronic ankle instability. It may help if you have had a weak or unstable ankle for more than 3 months and haven't had prior ankle surgery.
Boston, MassachusettsAges 18–65 - NCT06244511Recruiting
Balance Exercises for Chronic Ankle Instability
This study compares two types of balance exercises (standing on one leg vs. standing on both legs) to see which works better for people with long-term ankle instability. If you have chronic ankle weakness after a sprain at least 6 months ago, this trial may help improve your balance and confidence.
IstanbulAges 18–50 - NCT04999904Recruiting
Balance training on uneven treadmill for unstable ankles
This study tests a special balance and movement training program on an uneven treadmill to improve ankle stability. It may help people whose ankles “give way” or keep getting sprained, but it requires specific timing after an ankle sprain and the ability to attend sessions for about 6 weeks.
Oceanside, CaliforniaAges 18–49 - NCT07188363Recruiting
Ankle Ligament Surgery Study
This trial is a study of people who have had ankle ligament surgery. It aims to learn more about how these surgeries work and help future patients.
Paris, ParisAges 7 years+ - NCT07606534Recruiting
Ankle, Hip, or Combined Exercises for Chronic Ankle Instability
This study compares three different exercise programs to strengthen your ankle and improve stability. If you have a history of ankle sprains with ongoing instability problems, this trial tests which type of strengthening works best to prevent future injuries and improve your ability to do sports.
LiègeAges 18–35 - NCT07581535Recruiting
Neck and Eye Exercises for Chronic Ankle Instability
This study tests whether specific exercises for your neck and eye movements can help improve balance and stability in ankles that frequently give way or feel unstable. The goal is to see if these exercises reduce symptoms and improve your ankle function.
Izmir, ÇiğliAges 18–45 - NCT07689747Recruiting
Brain training and ankle tests for athletes with weak ankles
This study tests if adding a special computer-based brain training activity to regular ankle function tests can help teenage and young adult athletes who have ongoing ankle problems. If you are a licensed football, basketball, or volleyball player aged 16–25 with chronic ankle instability for at least a year, you may be eligible.
Istanbul, SarıyerAges 16–25 - NCT06552533Recruiting
Strengthening with jumps for ankle stability
This trial compares two types of leg exercises to see which better helps athletes with chronic ankle instability that did not heal with usual rehab. You would do resistance training alone or combined with jumping exercises.
Lahore, Punjab ProvinceAges 18–35 - NCT07252219Recruiting
How ankle muscle fatigue affects balance in unstable ankles
This study looks at how getting your ankle muscles tired changes your ability to sense force and control movement. It compares people with chronic ankle instability to healthy volunteers to find better ways to prevent re-injury.
LjubljanaAges 18–45 - NCT06118879Recruiting
How ankle instability affects movement in athletes
This study looks at how ankle instability affects movement control in athletes. If you have chronic ankle problems, you might help researchers understand how to improve treatment and prevention.
TaipeiAges 18–40 - NCT03643926Recruiting
Arthroscopic vs open surgery for ankle instability
This trial compares two surgical approaches to treat ongoing ankle “giving way” or instability. It aims to find which method works better for people whose ankle instability has lasted at least several months.
Belo Horizonte, Minas GeraisAges 18–65 - NCT07760233Recruiting
Balance training with eye exercises for unstable ankles
This study tests whether adding eye exercises to standard balance training helps amateur athletes with chronic ankle instability. It aims to improve ankle stability and reduce the feeling of the ankle 'giving way'.
Istanbul, TurkeyAges 18–35 - NCT07728526Recruiting
Eye exercises plus balance training for ankle instability
This study tests whether adding specific eye-movement exercises to standard balance training helps athletes with long-term ankle instability. It may improve your ankle control and reduce the feeling of your ankle giving way.
IstanbulAges 18–35 - NCT06499935Recruiting
Taping for ankle instability in athletes
This study tests whether taping can change how pressure is distributed on your foot while playing sports. It may help if you have long-term ankle instability from past sprains.
BeirutAges 18–28 - NCT07470021Recruiting
Numbing injection for pain relief after ankle surgery
This study tests whether a numbing injection around the ankle nerves before surgery can reduce pain and help you recover faster after ankle arthroscopy. It is for people having this keyhole surgery and staying in the hospital for a short time.
Hangzhou, ZhejiangAges 18–65 - NCT06868316Recruiting
Sound-guided walking training for chronic ankle instability
This study tests whether using sound cues while walking can improve balance and ankle stability in people with chronic ankle instability. You may be eligible if you have had repeated ankle sprains and a feeling of your ankle "giving way" in the last 6 months.
Lexington, KentuckyAges 18–45 - NCT06898554Recruiting
Understanding Ankle Control in Athletes with Unstable Ankles
This trial studies how your brain and spinal cord control your ankle if you have chronic ankle instability (a long-term wobbly ankle). It is for athletes between 18 and 25 who play team sports and have had repeated ankle sprains.
IstanbulAges 18–25 - NCT07338825Enrolling by invitation
Ankle instability study for Egyptian soccer players
This study looks at how common ankle instability is among soccer players in Egypt. The goal is to understand how many players have ongoing ankle issues, which may help improve future training or treatment.
CairoAges 8–35 - NCT07726810Recruiting
Exercises with music beats for ankle sprain recovery
This study tests if adding rhythmic music or sounds to special balance and stability exercises helps people recover better from a mild to moderate lateral ankle sprain (an injury to the outer side of the ankle). It may be a good option if your ankle sprain happened 2 to 8 weeks ago and you haven't had ankle surgery before.
Lahore, Punjab ProvinceAges 18–30 - NCT07283276Recruiting
Core training vs cognitive training for ankle instability
This study tests whether special core exercises or mental training can help improve your balance and control after repeated ankle sprains. If you have chronic ankle instability, this could help you find which type of training works best.
CairoAges 18–30 - NCT06576687Enrolling by invitation
Brain and nerve study for ankle instability
This study looks at how your brain and nerves control balance if you've had ankle sprains or feel your ankle giving way. Healthy people and those with ankle problems are invited to help researchers understand ankle instability better.
Omaha, NebraskaAges 19–45 - NCT07731035Recruiting
Balance and foot exercises for ankle instability
This study tests if combining core stability training with foot exercises helps people with chronic ankle instability. It compares these exercises to either core training alone or no treatment to see which works best.
Al MansurahAges 18–44 - NCT07401095Recruiting
BioBrace for Arthroscopic Ankle Ligament Repair
This trial is for people who need a first-time arthroscopic Brostrom repair to fix a loose ankle ligament. It uses a special material called BioBrace to help the repair heal better.
Greenfield, IndianaAges 18 years+
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Common questions
- Are there clinical trials for ankle instability?
- Yes. Clin2 currently lists 30 recruiting ankle instability studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ankle instability trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ankle instability trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.