Clinical trials
Anterior Cruciate Ligament clinical trials
Below are recruiting anterior cruciate ligament clinical trials, each written for real people, not researchers. We’re tracking 152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07636278Recruiting
Augmented Reality guidance for ACL knee surgery
This trial tests whether using augmented reality (special computer graphics overlaid on surgical video) during ACL reconstruction surgery helps surgeons perform the procedure more accurately. You would undergo standard knee surgery, but the surgeon would have real-time computer guidance to assist with precision.
Milan, MichiganAges 18 years+ - NCT07671729Recruiting
Comparing two tendon grafts for ACL surgery
This study compares two types of tendon grafts (from your kneecap tendon or from a tendon in your leg) for ACL reconstruction. The goal is to see which one works better for getting you back to normal activity.
Istanbul, BesiktasAges 18–50 - NCT07129694Enrolling by invitation
Testing a new lab-grown ligament for ACL repair
This study tests a new, lab-grown ligament made from biological tissue for ACL reconstruction. It may offer a regenerative option for people with a recent ACL tear who need surgery.
Hirosaki, AomoriAges 18–44 - NCT06892899Enrolling by invitation
Exercise study for knee health after ACL surgery
This study tests whether a specific exercise program can improve knee health in people who have had ACL surgery. It aims to understand how exercise affects the knee after injury and may help prevent arthritis.
Oslo, OsloAges 16–40 - NCT06755398Enrolling by invitation
Cognitive exercises after ACL knee surgery
This trial tests whether adding mentally challenging exercises to physical therapy helps improve balance, joint awareness, and reaction time after ACL reconstruction. It may be a good fit if you are at least 8 weeks post-surgery, have completed initial rehab, and meet specific recovery milestones.
AntalyaAges 20–40 - NCT06668376Enrolling by invitation
Incrediwear recovery products after ACL repair surgery
This study is testing Incrediwear recovery products (like sleeves or wraps) to see if they help reduce pain and swelling and improve healing after ACL repair. If you're having ACL surgery and meet the health requirements, you may be able to join.
Denton, TexasAges 18–65 - NCT06189573Enrolling by invitation
ACL repair: quadriceps vs patellar tendon graft
This trial compares two ways to rebuild a torn ACL using either a piece of your quadriceps tendon (with a small bone piece) or a piece of your patellar tendon (with bone). The goal is to find which graft works best for long-term stability and recovery.
Mexico City, Mexico CityAges 15–55 - NCT04944693Enrolling by invitation
Study of knee ligament surgery outcomes using MRI details
This study looks at how a specific knee bone alignment issue seen on MRI relates to how well ACL surgery works afterward. It may help doctors better predict outcomes after ACL reconstruction.
BeijingAges Any age - NCT04650568Enrolling by invitation
Stem cell treatment after ACL ligament surgery
This trial studies whether adding mesenchymal stem cells during ACL (knee ligament) reconstruction helps the knee heal better. You might be eligible if your ACL injury is recent and you’re having a specific type of graft surgery.
Chicago, IllinoisAges 18–60 - NCT07671430Recruiting
Psychological care before ACL surgery
This trial tests if extra psychological support before anterior cruciate ligament (ACL) surgery helps people who are very afraid of the operation. You would attend remote counseling sessions to see if they improve your recovery.
ParisAges 18 years+ - NCT04956536Enrolling by invitation
ACL injury study using your pre-surgery MRI
This trial studies ACL (knee ligament) injuries and how the tibia (shin bone) shifts, using MRI scans taken before surgery. It may help doctors better understand knee instability and improve how ACL injuries are evaluated and treated.
BeijingAges 18 years+ - NCT06178497Recruiting
5-Year Check-In After ACL Repair
This study checks on people who had ACL (anterior cruciate ligament) repair surgery 5 years ago to see how well their knee is doing. It looks at a specific type of ACL tear (a 'proximal' tear) and helps doctors understand long-term results.
Lille, Choisir Une RégionAges 18 years+ - NCT06240780Enrolling by invitation
Incrediwear recovery study for ACL and MCL surgery
This trial tests whether wearing Incrediwear clothing helps you recover faster after arthroscopic knee surgery for ACL or MCL tears. It is designed for people about to have surgery and who want to improve their healing process.
Oklahoma City, OklahomaAges 18–65 - NCT05968729Recruiting
Study testing walking changes after ACL surgery
This study looks at how your walking pattern adapts when you follow a purposely uneven walking setup. It may help researchers understand recovery after ACL surgery and how to improve return-to-sport safety.
Storrs, ConnecticutAges 18–30 - NCT05972876Recruiting
Blood-flow restriction rehab after ACL surgery
This trial looks at how well your ACL graft (the repaired tissue) heals after ACL reconstruction when you use a specific rehab method called blood-flow restriction training. It may help your care team understand whether this rehab approach leads to better healing and function.
Sittard, LimburgAges 18–65 - NCT04462458Recruiting
Study tracking outcomes after ACL reconstruction surgery
This is a study that follows adults who had an ACL tear treated with ACL reconstruction. It helps understand how the surgical device/material performs in real-world care.
InnsbruckAges 18 years+ - NCT06662955Recruiting
Exercise with sound cues after ACL reconstruction
This study tests if adding sounds (like a metronome beat) to your rehab exercises helps your leg muscles work better after ACL reconstruction. It is for athletes who had their ACL surgery within the past 2 weeks and are ready to start moving.
Salaya, Changwat Nakhon PathomAges 18–35 - NCT06688344Recruiting
Shock wave therapy after ACL surgery
This trial tests if adding focused shock wave therapy to standard rehab can improve recovery after ACL reconstruction using a hamstring graft. It may help reduce pain and speed up healing.
IstanbulAges 18–45 - NCT07020312RecruitingPhase 2
Brain training to improve muscle recovery after joint surgery
This trial tests whether brain-computer interface training can help you regain muscle control more effectively after knee or hip surgery. It focuses on four common procedures and uses neurofeedback to optimize muscle activation during recovery.
Chicago, IllinoisAges 18 years+ - NCT07128602Recruiting
Brain stimulation to help quadriceps after ACL surgery
This study tests whether a gentle, non-invasive brain stimulation can improve thigh muscle function in women recovering from ACL reconstruction. If you are between 2 and 6 months post-surgery, you may be able to join.
Glenside, PennsylvaniaAges 18–35 - NCT06991192Recruiting
ACL recovery with exercise and emotional support
This study tests a rehab program for teens and young adults who had ACL surgery. It combines physical therapy with extra mental and emotional support to help them get back to sports safely.
Bloomington, MinnesotaAges 15–21 - NCT07411625Recruiting
Pre-surgery exercise program for ACL injury patients
This trial tests whether doing special exercises before ACL surgery (called prehabilitation) helps you recover better after the operation. It's for people who have a first-time ACL tear and are scheduled for reconstruction surgery using a tendon from their own body.
NantesAges 18 years+ - NCT06973642Recruiting
Home-based rehab after ACL surgery via phone
This trial tests whether a home-based rehab program using your phone can help people recover after anterior cruciate ligament (ACL) reconstruction. It aims to see if remote physical therapy is as effective as in-person sessions.
Jackson, MississippiAges 18 years+ - NCT06636045Enrolling by invitation
Blood flow restriction after ACL surgery with quad graft
This study tests whether using a special blood flow restriction cuff after ACL surgery helps you recover faster and stronger. It is for people having ACL reconstruction using their own quadriceps tendon for the first time.
Kansas City, KansasAges 14–40
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Common questions
- Are there clinical trials for anterior cruciate ligament?
- Yes. Clin2 currently lists 152 recruiting anterior cruciate ligament studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament (ACL) Reconstruction
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.