Clinical trials
ARDS (Moderate or Severe) clinical trials
Below are recruiting ards (moderate or severe) clinical trials, each written for real people, not researchers. We’re tracking 1,505 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05578742Recruiting
Test breathing support patterns in moderate to severe ARDS
This trial studies how adjusting ventilator settings can better match the lungs’ ability to move air and oxygen in people with moderate to severe ARDS. It may help doctors tailor breathing support for different “lung mechanics” patterns, especially during the first days after intubation.
Angers, Maine et LoireAges 18 years+ - NCT05234463Recruiting
Study links complement activity to IgA kidney disease severity
This study looks at how parts of the immune system (called complement) may relate to how severe IgA kidney disease is. It may help doctors understand disease activity better, even if the study is mainly observational.
StrasbourgAges 18 years+ - NCT05310461Recruiting
Early or delayed valve surgery for mixed heart valve disease
This study compares doing aortic valve replacement sooner versus waiting, in people with moderate aortic valve narrowing plus at least moderate leakage in the mitral valve. It aims to see which timing improves heart symptoms and outcomes while keeping treatment safe.
BernAges 18 years+ - NCT06189963RecruitingPhase 1/Phase 2
Cell therapy trial for moderate Alzheimer's disease
This trial tests a new immune cell therapy (SNK01) for people with moderate Alzheimer's disease. The goal is to see if it can slow down memory and thinking decline.
Glendale, CaliforniaAges 40–85 - NCT06400095Recruiting
Breathing Machine Patterns to Predict Recovery in Severe Lung Failure
This study looks at how the breathing machine settings and lung function can help predict recovery in people with severe ARDS. You may be able to join if you are on a ventilator for sudden lung failure and have severe ARDS, as long as you don't have certain other health issues.
Saint Cloud, MinnesotaAges 19–80 - NCT02498587Recruiting
Study of severe breathing illness over a short period
This study looks at people who recently had fever and cough along with trouble breathing, to better understand severe acute respiratory illness. By joining, you may help researchers identify patterns that could improve recognition and care.
Melbourne, VictoriaAges Any age - NCT04456816RecruitingPhase 2
Drug test for IgA? No—anti-PLA2R positive immune kidney disease
This Phase 2 trial studies AP1189 in people with a specific immune-related kidney disease called iMN and very high urine protein. It aims to see whether the drug is safe and tolerable and if it can reduce protein in the urine.
AarhusAges 18–85 - NCT07694869RecruitingPhase 1
Study of ammoxetine tablets in people with moderate kidney problems
This trial tests how a new drug called ammoxetine works in people with moderate kidney impairment compared to those with normal kidney function. It aims to find the right dose and understand how the drug is processed by the body.
Hefei, AnhuiAges 18–75 - NCT07546097RecruitingPhase 4
Upadacitinib vs Steroids for Severe Ulcerative Colitis
This study compares a newer medication called upadacitinib to traditional steroids for treating acute severe ulcerative colitis (sudden worsening of UC with bloody diarrhea and urgent symptoms). The goal is to see which approach works better as a first treatment.
Ankang, ShaanxiAges 18–85 - NCT07550673RecruitingPhase 4
Upadacitinib vs. Infliximab for Severe Ulcerative Colitis
This study compares two medications—upadacitinib and infliximab—as second-line treatments for acute severe ulcerative colitis (a serious flare of inflammatory bowel disease). The trial will help doctors understand which treatment works better when standard first-line therapy hasn't controlled the inflammation.
Ankang, ShaanxiAges 18–85 - NCT06732648RecruitingPhase 2/Phase 3
Testing a new drug for severe brain swelling after a large stroke
This trial tests a new drug called HRS8179 to reduce severe brain swelling after a large stroke. If you have a major stroke on one side of the brain and can start treatment within 10 hours, this study may help prevent dangerous pressure buildup.
Beijing, Beijing MunicipalityAges 18–80 - NCT06647784Recruiting
Side versus belly lying for ARDS patients
This trial compares lying on your side versus lying on your belly to improve oxygen levels in patients with acute respiratory distress syndrome (ARDS). It may help doctors choose the best position to help you breathe better.
Bastia, FranceAges 18 years+ - NCT07033468Recruiting
Virtual reality cognitive training for mild to moderate dementia
This study tests whether using a full-immersive virtual reality program can help improve thinking and memory skills in people with mild or moderate dementia. It aims to see if this type of training is both possible and helpful.
New Taipei CityAges 55 years+ - NCT06598930Recruiting
Nurse-led follow-up after mild lung blood clot
This study compares two ways of following up after a non-severe pulmonary embolism: standard medical care alone versus intensive monitoring that includes an advanced practice nurse. The goal is to see if the nurse-led follow-up improves your recovery and quality of life.
DijonAges 18 years+ - NCT05678699Recruiting
Medicaid policy study to improve maternal care equity
This study examines how Medicaid policy changes affect racial equity in severe maternal health complications and deaths. Instead of recruiting individual patients, researchers will use existing healthcare and program data from people who use Medicaid and from healthcare systems in Pennsylvania.
Pittsburgh, PennsylvaniaAges Any age - NCT06577402Recruiting
Study on energy and protein in severe brain injury patients
This study measures how your body uses energy and protein if you are in the ICU with a severe brain injury while on a breathing machine. It can help doctors better understand your recovery needs.
Nanjing, JiangsuAges 18–85 - NCT07150559Recruiting
Arch-clamping under mild cooling for acute aortic dissection
This trial tests a surgical technique called arch-clamping under mild hypothermia (cooling the body slightly during surgery) to treat acute type A aortic dissection. It may help patients who need immediate total aortic arch replacement.
Beijing, Beijing MunicipalityAges 18–70 - NCT06572943Recruiting
Moderate exercise during pregnancy and heart health
This study looks at whether doing moderate exercise during pregnancy is safe and helpful for both mom and baby's heart health. If you are in your first trimester and do not have any high-risk conditions, you might be able to join.
IoanninaAges 18 years+ - NCT07010237RecruitingPhase 2
Lower-dose immune therapy plus hetrombopag for older adults with severe aplastic anemia
This trial tests a milder version of immunosuppressive therapy combined with hetrombopag (a drug that helps bone marrow make blood cells) in people aged 65 years and older with severe aplastic anemia. The goal is to see if this approach is both safer and effective for older patients.
Tianjin, Tianjin MunicipalityAges 65 years+ - NCT06985706RecruitingPhase 3
Comparing two treatments for diabetic eye swelling after initial injections
This trial tests whether switching from anti-VEGF injections to a special laser is better than continuing injections alone for people with diabetic macular edema whose central retinal thickness has dropped below 400 microns after the first year of treatment.
BelfastAges 18 years+ - NCT06751784RecruitingPhase 2
Fampridine's effect on memory in mild to moderate depression
This study tests whether the drug fampridine can improve working memory (like short-term memory and focus) in people with mild to moderate depression. The trial is run by the University of Basel and involves multiple visits.
Basel, Canton of Basel-CityAges 18–55 - NCT07457125RecruitingPhase 1/Phase 2
Exosome therapy for mild to moderate Alzheimer's disease
This trial tests a new drug made from stem cell exosomes (CB-Exo-A600) to see if it can help people with mild to moderate Alzheimer's disease. It aims to slow down symptoms and improve quality of life.
BeijingAges 50 years+ - NCT02471443Recruiting
Laparoscopic surgery for severe endometriosis involving bowel
This trial studies how well a minimally invasive (laparoscopic) surgery works for people with severe endometriosis that affects the bowel. It may help improve symptoms and quality of life, and it focuses on planned surgery for this specific type of endometriosis.
Guildford, SurreyAges Any age - NCT06473740RecruitingPhase 4
Gene therapy plus angioplasty for severe leg blockages
This study tests if adding gene therapy to a standard leg artery-opening procedure (angioplasty or stenting) helps people with severe leg pain or non-healing wounds due to blocked arteries. It may improve blood flow and save the leg from amputation.
Blagoveshchensk, Amur OblastAges 18 years+
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Common questions
- Are there clinical trials for ards (moderate or severe)?
- Yes. Clin2 currently lists 1,505 recruiting ards (moderate or severe) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ards (moderate or severe) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ards (moderate or severe) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.