Clinical trials
Atrial Fibrillation, Paroxysmal or Persistent clinical trials
Below are recruiting atrial fibrillation, paroxysmal or persistent clinical trials, each written for real people, not researchers. We’re tracking 474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03642509Recruiting
Compare a heart procedure to blood-thinner pills for stroke prevention
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
Aarhus, Central JutlandAges 18 years+ - NCT06200311Recruiting
Atrial fibrillation ablation to prevent heart damage in women and men
This trial tests whether a procedure called AF ablation (which treats irregular heartbeats) can stop further damage to the heart muscle caused by atrial fibrillation. It may help people with both atrial fibrillation and early signs of heart muscle weakening.
GroningenAges 65–80 - NCT06630936Recruiting
Studying atrial fibrillation with mitral regurgitation
This trial tests a treatment for people with atrial fibrillation who also have a leaky mitral valve. It aims to see if treating both conditions together can improve symptoms.
Hangzhou, ZhejiangAges 18–80 - NCT06988202Enrolling by invitation
Comparing repeat ablation methods for atrial fibrillation
This trial compares different techniques for a second heart ablation procedure in people with atrial fibrillation (AFib) who have already had one ablation. It aims to find the best approach to stop AFib from coming back.
Rochester, New YorkAges 18 years+ - NCT06212674RecruitingPhase 4
Stroke prevention: combined heart procedure for atrial fibrillation
This study tests a combined approach — a catheter ablation to fix the irregular heartbeat (atrial fibrillation) and a device to close the left atrial appendage — in people who recently had a stroke caused by a clot. The goal is to prevent future strokes and reduce the need for long-term blood thinners.
Katowice, Upper SilesiaAges 18–75 - NCT06401616RecruitingPhase 4
Stopping blood thinners after heart surgery for atrial fibrillation
This trial tests whether it is safe for patients with atrial fibrillation to stop taking blood thinners after they have had heart surgery, including closure of the left atrial appendage. The goal is to see if these patients can avoid long-term medication without increasing the risk of stroke.
Copenhagen, Capital RegionAges 18 years+ - NCT07447297Recruiting
Early Rhythm Control for Device-Detected Fast Heart Episodes
This trial tests whether starting treatment early to control your heart's rhythm can help people with a heart device who have short bursts of a fast heartbeat (called atrial high rate episodes) but haven't yet been diagnosed with atrial fibrillation on a standard EKG or Holter monitor.
Seoul, SeoulAges 19 years+ - NCT07563257Recruiting
Comparing Two Mapping Catheters for Heart Rhythm Ablation
This trial compares two types of specialized catheters used during heart rhythm ablation procedures to help doctors confirm they've created the right burn patterns. If you're having ablation for persistent atrial fibrillation or flutter with complex burn lines planned, this trial may help improve how your procedure is done.
Be’er Ya‘aqovAges 18 years+ - NCT04404465Enrolling by invitation
Test blood/heart signals to understand atrial fibrillation changes
This study looks at early changes in the heart related to atrial fibrillation (AF) using health data and biomarkers. It aims to find better ways to predict or understand AF, especially around procedures like ablation or cardioversion.
San Francisco, CaliforniaAges 18 years+ - NCT07779213Recruiting
Smartphone camera test for atrial fibrillation
This study tests whether a smartphone camera can detect an irregular heartbeat (atrial fibrillation) by measuring blood flow through your fingertip. If it works, it could make checking your heart rhythm easier at home.
Jonesboro, ArkansasAges 22 minutes+ - NCT07175428RecruitingPhase 2
Safety of a New Blood Thinner in AFib Patients
This study tests the safety of a new blood thinner for people with atrial fibrillation (AFib) who need long-term stroke prevention. If you qualify, the study will compare this medication to standard anticoagulation therapy.
Dothan, AlabamaAges 18 years+ - NCT05991700RecruitingPhase 1/Phase 2
Grape Powder to Prevent Irregular Heartbeat After Valve Surgery
This trial tests whether a grape powder supplement (rich in plant compounds called anthocyanins) can help prevent a common heart rhythm problem (atrial fibrillation) after mitral valve repair surgery. It is for people who are scheduled for this surgery and do not have certain heart or health issues.
Ann Arbor, MichiganAges 18–79 - NCT07173998Recruiting
Quality of life after heart surgery with irregular heartbeat
This study looks at quality of life in people who develop atrial fibrillation (an irregular heartbeat) after heart surgery. Researchers will ask you to fill out surveys to understand how this condition affects your daily life.
Boston, MassachusettsAges 18–100 - NCT07217067RecruitingPhase 2
Study of PKN605 for people with atrial fibrillation
This trial tests a new medicine called PKN605 for people with atrial fibrillation (irregular heartbeat). The goal is to see if it can safely help control heart rhythm. You will need to have had at least two AF episodes recently and meet other heart health criteria.
Tupelo, MississippiAges 18 years+ - NCT07227532Recruiting
Testing a new catheter for atrial fibrillation treatment
This study tests a new catheter system, called Varipulse, to see if it's safe and effective for treating atrial fibrillation (AF), a heart rhythm problem. People with short-lasting AF who haven't been helped by medication may be able to join.
Phoenix, ArizonaAges 22 years+ - NCT04685317Recruiting
Sentinel brain-protection device during atrial fibrillation ablation
This trial tests whether a specialized “brain protection” device can improve safety during atrial fibrillation (AF) catheter ablation. It may help reduce the risk of stroke or related complications while treating AF.
Rochester, MinnesotaAges 18 years+ - NCT03862859RecruitingPhase 4
Warfarin safety for people with atrial fibrillation on dialysis
This trial studies whether the blood thinner warfarin is safe and effective for preventing stroke and blood clots in people who have atrial fibrillation and need long-term dialysis. It may help your care team better balance clot prevention against bleeding risk.
Herlev, HerlevAges 18 years+ - NCT07580547Recruiting
Atrial fibrillation ablation: study on sex differences
This research compares how atrial fibrillation (AF) affects men and women differently. If you are having your first catheter ablation for AF and are between 18 and 80, this study may help doctors understand outcomes better.
Be’er Ya‘aqovAges 18–80 - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Little Rock, ArkansasAges 18 years+ - NCT04947657Recruiting
Atrial fibrillation blood and heart scan pilot during ablation
This study looks at blood-related “clotting” signs and heart scan results in people with atrial fibrillation (AF) who are getting a catheter ablation. It may help doctors better understand AF and choose treatments more precisely.
New Orleans, LouisianaAges 18–120 - NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT05332457Recruiting
Beta-blocker effects on heart rate and exercise capacity in atrial fibrillation
This study looks at how taking a beta-blocker affects your resting heart rate during activity and how fit your heart and lungs are during an exercise test. It may help clarify whether the way the medication controls heart rate is linked to better exercise tolerance in people with persistent atrial fibrillation.
TaipeiAges 20 years+ - NCT05366361Recruiting
Study of persistent atrial fibrillation during heart procedures
This study looks at what happens in the heart in people with persistent atrial fibrillation when they undergo an ablation or Maze surgery. It may help doctors better understand the condition and improve future care for people needing these procedures.
Stanford, CaliforniaAges 22–80 - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80
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Common questions
- Are there clinical trials for atrial fibrillation, paroxysmal or persistent?
- Yes. Clin2 currently lists 474 recruiting atrial fibrillation, paroxysmal or persistent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation, paroxysmal or persistent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation, paroxysmal or persistent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.