Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06061978Recruiting
Pacing after a heart procedure for rapid atrial fibrillation
This trial studies whether a special type of pacing (stimulating the heart's natural electrical system) works better than standard pacing after a procedure to control very fast heart rhythms. It's for people who already have a pacemaker and are getting a specific treatment for atrial fibrillation.
CaenAges 18 years+ - NCT02997254Recruiting
Testing computer methods that analyze atrial fibrillation heart signals
This study compares different computer “analysis methods” that look at real-time heart recordings from people with atrial fibrillation. It may help improve how atrial fibrillation is evaluated during/after an ablation procedure.
Stanford, CaliforniaAges 21–90 - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80 - NCT05997914Enrolling by invitation
Storytelling to reduce stroke risk in African Americans with atrial fibrillation
This study tests whether a storytelling program can help African American patients with atrial fibrillation start taking blood thinners as recommended by their doctor. The goal is to reduce stroke risk and improve health outcomes.
Jacksonville, FloridaAges 18 years+ - NCT05411614Recruiting
Testing two heart procedures for atrial fibrillation in heart failure
This study compares two different ablation procedures (treatments that target heart rhythm triggers) for people with atrial fibrillation and reduced heart pumping. It aims to see which approach works best and is safest for improving your heart rhythm when you also have heart failure.
ChertseyAges 18 years+ - NCT05844501RecruitingPhase 4
Ondansetron before heart ablation for atrial fibrillation
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Indianapolis, IndianaAges 18–100 - NCT05836987RecruitingPhase 3
Smartwatch-guided blood thinners for intermittent atrial fibrillation
This study tests whether using a smartwatch to monitor your heartbeat can safely guide when to take blood thinners. If you have intermittent atrial fibrillation, you may be able to avoid taking blood thinners when your heart rhythm is normal.
Phoenix, ArizonaAges 22–85 - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05794386Recruiting
Ablation plan guided by left-heart scar map for persistent atrial fibrillation
This study tests whether using a 3D heart “scar map” helps doctors choose a better catheter ablation strategy for people with persistent atrial fibrillation (AF). It may help reduce ongoing AF by targeting the scar area in the left atrium.
Seoul, Jongno-guAges 19 years+ - NCT05723536Recruiting
Comparing two procedures for persistent atrial fibrillation
This study compares two ways to treat persistent atrial fibrillation (an irregular heartbeat that lasts for a long time). One method uses a catheter to treat the heart from the inside, and the other combines that with a small procedure on the outside of the heart. The goal is to see which approach works better for people whose symptoms haven't improved with medication.
BarcelonaAges 18–75 - NCT05504356Recruiting
Study to improve atrial fibrillation ablation and new therapies
This study looks at what results from atrial fibrillation ablation (a heart rhythm procedure) and newer related therapies. If you recently had the procedure—or are scheduled for it soon—you may use an app and website to share information that helps researchers compare outcomes and improve care.
San Francisco, CaliforniaAges 18 years+ - NCT05511389Recruiting
Testing better electrode placement for heart rhythm shock
This study tests whether two different positions of the electrodes (pads) used for an electrical shock work equally well for people with atrial fibrillation or flutter. It may help improve how safely and effectively the shock restores a normal rhythm.
Hamilton, OntarioAges 18 years+ - NCT05407415Enrolling by invitation
Using a phone ECG monitor to improve care for atrial fibrillation
This trial studies whether sending heart rhythm recordings from a phone (using the KardiaMobile ECG device) can improve health care use and patient experience for people with atrial fibrillation. It may help your care team monitor you more smoothly—if you meet the study requirements.
Chicago, IllinoisAges 18–90 - NCT05366361Recruiting
Study of persistent atrial fibrillation during heart procedures
This study looks at what happens in the heart in people with persistent atrial fibrillation when they undergo an ablation or Maze surgery. It may help doctors better understand the condition and improve future care for people needing these procedures.
Stanford, CaliforniaAges 22–80 - NCT05378035Recruiting
DOAC interruption study for Chinese people with atrial fibrillation
This trial studies how safely and effectively to pause a blood thinner (a DOAC) for about 48 hours before an elective procedure in people with atrial fibrillation. It may help confirm the best way to reduce bleeding risk without raising stroke risk.
Hong KongAges 18–80 - NCT05293080RecruitingPhase 3
Early heart rhythm treatment to help prevent stroke
This trial tests an early treatment approach for people who had a recent ischemic stroke (a stroke caused by a blocked blood vessel) and have an irregular heart rhythm called atrial fibrillation (AF). It aims to lower the chance of having another stroke by treating AF as early as possible after the stroke.
HamburgAges 18 years+ - NCT05144503Recruiting
Test of a new catheter procedure for irregular heart rhythm
This study checks how safe and effective a special catheter procedure (SpherePVI) is for treating paroxysmal (comes and goes) or persistent atrial fibrillation. You may be considered if your atrial fibrillation keeps returning and you’ve already tried at least one medication but it didn’t work or you couldn’t tolerate it.
VilniusAges 18–75 - NCT05164107Recruiting
Test a new pulsed-field catheter procedure for atrial fibrillation
This trial tests a new pulsed-field device used during an atrial fibrillation (AF) catheter ablation, aiming to improve safety and effectiveness. It’s for people who have AF and are planning an AF ablation procedure.
PragueAges 18–75 - NCT05115214Recruiting
Device test for treating irregular heartbeat with AF ablation
This trial studies a heart procedure using the Affera SpherePVI system to treat paroxysmal (comes and goes) or persistent atrial fibrillation. It’s for people who still have symptoms despite at least one anti-arrhythmia medicine, and who are good candidates for catheter ablation.
PragueAges 18–75 - NCT05014802Recruiting
MRI scans before heart surgery to predict post-surgery atrial fibrillation
This study uses an MRI scan before heart surgery to look for heart scarring that may predict who will develop atrial fibrillation afterward. Knowing the risk ahead of time could help doctors monitor you more closely and plan prevention.
Covington, LouisianaAges 40–120 - NCT05009797Recruiting
Study follow-up after catheter ablation for atrial fibrillation
This trial is looking at what happens after a heart procedure called catheter ablation for atrial fibrillation (an irregular heartbeat). It mainly collects follow-up outcomes to better understand recovery and results for patients.
LilleAges 18 years+ - NCT04642430RecruitingPhase 4
Test of blood thinners comparing rivaroxaban vs apixaban
This trial compares the bleeding risk of two commonly used blood thinners—rivaroxaban and apixaban—in people with atrial fibrillation (AF). If you’re starting an anticoagulant for a new AF diagnosis, this may help doctors choose the safer option for you and others.
Victoria, British ColumbiaAges 18 years+ - NCT04404465Enrolling by invitation
Test blood/heart signals to understand atrial fibrillation changes
This study looks at early changes in the heart related to atrial fibrillation (AF) using health data and biomarkers. It aims to find better ways to predict or understand AF, especially around procedures like ablation or cardioversion.
San Francisco, CaliforniaAges 18 years+ - NCT04267159Recruiting
Treatment plan for sudden irregular heartbeat in the ER
This trial looks at how to manage a new, sudden irregular heartbeat (atrial fibrillation or atrial flutter) when you first arrive in the emergency room. It may help by testing an “elective” approach to rhythm control, depending on your heart rate and overall safety factors.
Jyväskylä, Central FinlandAges Any age
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 543 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.