Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04148625Enrolling by invitation
Sub-xiphoid hybrid maze for persistent atrial fibrillation after failed ablation
This trial studies a hybrid heart procedure to treat persistent atrial fibrillation in people whose previous catheter ablation did not work. It aims to improve heart rhythm and reduce ongoing symptoms by using a planned combination of techniques and careful follow-up.
Ages 18–80 - NCT03868150RecruitingPhase 4
Preventing an abnormal heart rhythm after heart surgery
This trial studies whether giving a medication (amiodarone) during and after certain heart surgeries can help prevent atrial fibrillation, an irregular heartbeat that can happen after surgery. It may help by aiming to stop this rhythm problem before it starts.
Stanford, CaliforniaAges 18 years+ - NCT03397602Recruiting
Exercise program for long-term atrial fibrillation
This trial studies how an exercise training program affects people with persistent or permanent atrial fibrillation (an irregular heart rhythm). It may help improve how you feel and how well your heart and body handle activity.
London, OntarioAges 40 years+ - NCT07877519Recruiting
Sedation options for pulsed field ablation in atrial fibrillation
This study compares two ways to keep patients comfortable during a procedure called pulsed field ablation for atrial fibrillation: conscious sedation (you're awake but relaxed) versus general anesthesia (you're fully asleep). The goal is to find which method works better and is safer for patients.
Beijing, Beijing MunicipalityAges 18–80 - NCT03272620Recruiting
Emergency atrial fibrillation patients invited to study
This study includes people who have atrial fibrillation and are seen in the emergency department. It aims to learn from emergency care and may help improve how atrial fibrillation is managed in the ER.
ViennaAges 18 years+ - NCT05928728RecruitingPhase 3
Colchicine for people with certain irregular heartbeats
This trial tests whether colchicine can help people with paroxysmal or persistent atrial fibrillation (AF), a type of irregular heartbeat, after a successful cardioversion. It may help reduce future AF problems, depending on the results.
HellerupAges 18 years+ - NCT07799519RecruitingPhase 2
Finerenone after heart procedure to lower atrial fibrillation return
This trial tests whether taking finerenone after a heart procedure to fix irregular heartbeat can help prevent atrial fibrillation from coming back. It's for people having their first such procedure and aims to improve long-term heart rhythm health.
TainanAges 18–80 - NCT07772518Recruiting
Comparing two guidance methods for pulsed field ablation in atrial fibrillation
This trial compares two ways of guiding a procedure to treat atrial fibrillation (an irregular heartbeat). One uses special sound waves to see inside the heart, and the other uses electrical mapping. Both are used with the FARAPULSE system to deliver a type of energy called pulsed fields to fixed areas of the heart.
ZagrebAges 18 years+ - NCT05598632Recruiting
People with atrial fibrillation registry to study stroke risk
This registry study follows people with atrial fibrillation to learn which risk factors are linked to stroke or blood clots traveling through the body. Your information helps improve how doctors predict risk and choose prevention strategies.
Beijing, Beijing MunicipalityAges 18–120 - NCT07649109RecruitingPhase 4
Heart Device Detected Irregular Heartbeats: Treatment Study
This study follows patients who have a heart rhythm device (pacemaker, defibrillator, or resynchronization device) and have experienced brief episodes of fast irregular heartbeats detected by the device. The study compares treatment approaches to understand which helps patients stay healthier and feel better.
TaipeiAges 18 years+ - NCT07630857Recruiting
Heart Mapping to Personalize Atrial Fibrillation Treatment
This trial tests a new way to map the heart's electrical signals to help doctors better target and treat atrial fibrillation (an irregular heartbeat). If you're having a procedure to treat AF, this study may help improve the success of your treatment.
Beijing, Beijing MunicipalityAges 18–80 - NCT07575867Recruiting
Reduced Blood Thinner Strategy After Heart Device Closure
This trial tests whether patients who receive a special device to close a hole in the heart (to prevent stroke from irregular heartbeat) can safely take fewer blood-thinning medications afterward. The study compares taking a standard blood thinner for 3 months versus taking aspirin only, to see which approach works best with fewer bleeding risks.
MoscowAges 18 years+ - NCT07535268Recruiting
Heart rhythm ablation outcomes in minority patients
This registry tracks outcomes for racial and ethnic minority patients undergoing a specific type of heart rhythm treatment (ablation) for atrial fibrillation. The goal is to understand how well this treatment works across different populations.
New York, New YorkAges 18 years+ - NCT07458191Recruiting
Apixaban safety and adherence for atrial fibrillation patients
This trial tests how well patients with atrial fibrillation take their apixaban medication and whether it is safe. It aims to see if using apixaban for the first time works well without causing bleeding problems.
SarajevoAges 18 years+ - NCT07444320Recruiting
Testing new energy pulses for atrial fibrillation treatment
This trial tests a new way to deliver energy (FARAPULSE PFA system) to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to see if these new waveforms can safely and effectively stop AF symptoms and improve quality of life.
SplitAges 18 years+ - NCT06832033Recruiting
Exercise program after atrial fibrillation ablation
This trial is testing whether a structured exercise program (combining cardio and strength training) can help people who have already had a procedure to treat atrial fibrillation. It aims to see if this type of training can improve heart health and quality of life.
Zaragoza, ZaragozaAges 18 years+ - NCT07358611Recruiting
Heart mapping-guided ablation for persistent atrial fibrillation
This trial tests whether using a special heart-mapping device during ablation (a procedure to fix irregular heartbeats) can improve outcomes for people with persistent atrial fibrillation and an enlarged left heart chamber.
BarcelonaAges 18 years+ - NCT07301190Recruiting
Study of PFLotus for persistent atrial fibrillation
This study tests a new device called PFLotus for people with persistent atrial fibrillation (AF), a type of irregular heartbeat. The goal is to see if it can help restore a normal heart rhythm in people who haven't gotten better with medicine.
ChengduAges 18–75 - NCT07281898Recruiting
Burst stimulation for paroxysmal atrial fibrillation
This trial tests a special type of pacing called burst stimulation to see if it can help people with paroxysmal atrial fibrillation (AF) who are already scheduled for their first catheter ablation. The goal is to improve outcomes and reduce AF episodes.
Wuhan, HubeiAges 18–80 - NCT07270757Recruiting
Pre-ablation exercise program for atrial fibrillation
This study tests whether a short exercise and education program before a first-time ablation for atrial fibrillation improves your recovery and heart fitness. It's for people with mild or no heart failure symptoms and a well-pumping heart.
Nanjing, Please SelectAges 18–70 - NCT07273994RecruitingPhase 4
Comparing two amiodarone doses after heart shock treatment for atrial fibrillation
This trial tests two different ways of taking amiodarone (a heart rhythm medicine) to keep your heart in a normal rhythm after a procedure called electrical cardioversion. It's designed for people with persistent atrial fibrillation (a fast, irregular heartbeat lasting at least 7 days).
BarcelonaAges 18 years+ - NCT04281329Recruiting
CT and heart MRI add-on for atrial fibrillation ablation
This trial studies whether CT scans and heart MRI scans (done around the time of atrial fibrillation ablation) can help care planning and results. It may help your team better understand your heart before and after the procedure.
ParisAges 18 years+ - NCT07130773Recruiting
Comparing two catheter types for atrial fibrillation ablation
This trial compares two types of special catheters (thin tubes) used during a procedure called ablation to treat atrial fibrillation (irregular heartbeat). It aims to see which catheter works better during the procedure, and may help improve future treatments for people with heart rhythm problems.
Lugano, Canton TicinoAges 18 years+ - NCT07122336Recruiting
A better way to treat persistent atrial fibrillation
This trial tests a new method to treat persistent atrial fibrillation (a long-lasting irregular heartbeat) to see if it helps patients who haven't been helped by medication. It focuses on cleaning up the back wall of the heart to restore a normal rhythm.
ShanghaiAges 18–80
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 543 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.