Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,351 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07666555RecruitingPhase 2
Culmerciclib rechallenge for HR+ HER2- breast cancer
This trial tests a new drug called Culmerciclib for women with advanced HR-positive, HER2-negative breast cancer that has stopped responding to a CDK4/6 inhibitor with hormone therapy. The goal is to see if giving this drug again can help when other treatments no longer work.
ShanghaiAges 18–75 - NCT07670273RecruitingPhase 2
Drug combo for advanced HER2 bile duct cancer
This trial tests a combination of three drugs (trastuzumab rezetecan, adebrelimab, and lenvatinib) as a first treatment for people with advanced HER2-positive or HER2-low bile duct or gallbladder cancer. The goal is to see if this combination helps shrink or control the cancer.
BeijingAges 18–75 - NCT07669220RecruitingPhase 2
Short radiation, immunotherapy, and chemo for advanced rectal cancer
This trial compares a new treatment approach—short-course radiation followed by an immunotherapy drug (PD-1 inhibitor) and chemotherapy (FOLFOX)—to the standard long-course chemoradiation for people with a specific type of advanced rectal cancer that is pMMR/MSS. The goal is to see if the shorter treatment works as well or better.
GuangzhouAges 18–75 - NCT07670013RecruitingPhase 2
SKB264 and glecirasib for advanced KRAS G12C lung cancer
This trial tests a new combination of two drugs (SKB264 and glecirasib) for people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. It aims to see if this combination can shrink tumors or slow their growth.
Hangzhou, ZhejiangAges 18–75 - NCT06675851RecruitingPhase 4
Dopamine changes in the brains of depressed and healthy people
This study uses brain scans to look at dopamine — a chemical messenger related to reward and mood — in people with depression and healthy volunteers. Researchers want to understand how dopamine changes in depression, which may lead to better treatments.
ViennaAges 18–65 - NCT06520683RecruitingPhase 3
Immunotherapy after surgery for high-risk stage II colorectal cancer
This trial tests whether a drug called an immune checkpoint inhibitor (PD-1 blocker) can help lower the risk of cancer returning after surgery. It is for people with a specific type of colorectal cancer (dMMR or MSI-H) that had certain high-risk features.
Guangzhou, GuangdongAges 18–80 - NCT06677814Recruiting
Anxiety risk test for men with premature ejaculation
This study aims to develop a tool to predict anxiety in men with premature ejaculation. Participants will fill out questionnaires to help build this model, which may lead to better support for emotional health.
Xi'an, ShaanxiAges 18 years+ - NCT07657234RecruitingPhase 1/Phase 2
Brain stimulation for depression in older adults
This study tests whether a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can help treat depression in people aged 60 and older. tDCS uses a mild electrical current to gently stimulate the brain and may improve mood when added to your current depression treatment.
Dallas, TexasAges 60 years+ - NCT07658898Recruiting
Brain stimulation for negative and cognitive symptoms in schizophrenia
This study tests a new type of brain stimulation called temporal interference to see if it can help with negative symptoms (like lack of motivation or emotion) and cognitive symptoms (like trouble with memory or focus) in schizophrenia. It uses a special head device to target a specific brain area.
ShanghaiAges 18–65 - NCT07662837Recruiting
Comparing Tai Chi and Qi Gong for Early Parkinson's
This study compares two gentle mind-body exercises, Tai Chi and Qi Gong, to see which one better helps people with early-stage Parkinson's disease. If you are between 50 and 65 and have stable medication, you may join to find out if these practices can improve your balance, movement, and well-being.
Lahore, Punjab ProvinceAges 50–65 - NCT06398496Recruiting
Exercise, gut health, mood in depression
This trial studies whether a 12-week exercise program can improve gut bacteria, mood, and thinking in people with depression. It may help if you are looking for a non-medication way to support your mental health.
Cork, Cork CountyAges 18–59 - NCT07654140RecruitingPhase 2
Testing a new drug for uncontrolled high blood pressure
This trial tests a new drug called SAL0140 for people whose high blood pressure is not controlled by current treatments. It may help lower blood pressure when other medications haven't worked well enough.
Beijing, Beijing MunicipalityAges 18–75 - NCT07652645Recruiting
DBT therapy for veterans with war-related PTSD
This trial tests a special type of therapy (Dialectical Behavior Therapy, or DBT) adapted for veterans with PTSD from war. It uses a mix of online sessions and homework to help you control emotions and reduce trauma symptoms.
Amstelveen, North HollandAges 18 years+ - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age - NCT07653893Recruiting
T-DXd for breast cancer that has spread to the brain
This study is looking at how well the drug trastuzumab deruxtecan (Enhertu) works for women and men with HER2-positive breast cancer that has spread to the brain. Researchers want to see how much of the drug gets into the spinal fluid and if it helps shrink brain tumors.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07651358Recruiting
Web Program to Help Pancreatic Cancer Patients Exercise and Eat Better
This study tests a personalized website program called COMPASS designed to help people with stage I-III pancreatic cancer improve their exercise and diet while receiving chemotherapy before surgery. The goal is to see if this program helps patients feel better and stay stronger during treatment.
Portland, OregonAges 18 years+ - NCT06240143RecruitingPhase 1/Phase 2
Intradermal immunotherapy for high-risk stage II melanoma
This trial tests if injecting two immunotherapy drugs (ipilimumab and nivolumab) just under the skin can help prevent high-risk stage II melanoma from spreading. It is for people who have recently had a thick melanoma removed and have not yet had a sentinel node biopsy.
AmsterdamAges 18 years+ - NCT06689254RecruitingPhase 2
Testing mifepristone for hard-to-treat PTSD in Dutch adults
This study tests a new medicine (mifepristone) to see if it helps people with PTSD that hasn't improved after standard treatments. You must be fluent in Dutch and have tried at least two PTSD treatments, including trauma-focused therapy.
Amsterdam, North HollandAges 18 years+ - NCT07640893RecruitingPhase 2
Testing a new injection for von Willebrand disease
This study tests whether SR604, a new injection given under the skin, can reduce bleeding episodes in people with von Willebrand disease (a condition where blood doesn't clot properly). The trial will measure how well it works, how safe it is, and how your body processes it.
ChangshaAges 18–65 - NCT07644052RecruitingPhase 3
Study of a new medicine to ease cannabis withdrawal
This study tests a new medicine, PP-01, to help adults who use cannabis daily and want to quit. It aims to reduce withdrawal symptoms like anxiety, irritability, and sleep problems during the first week after stopping.
Little Rock, ArkansasAges 18–55 - NCT07638683RecruitingPhase 2
Teclistamab and Daratumumab for New Multiple Myeloma With Amyloidosis
This trial tests a combination of two newer cancer-fighting drugs (teclistamab and daratumumab) to treat people who have just been diagnosed with multiple myeloma—a blood cancer—and also have light chain amyloidosis, a condition where abnormal proteins build up in organs. The goal is to see if this combination works better and is safe for newly diagnosed patients.
ShanghaiAges 18 years+ - NCT07644286RecruitingPhase 2
Pirfenidone and immunotherapy with optional radiation for advanced colorectal cancer
This study tests a combination of three treatments—pirfenidone (an anti-scarring drug), a PD-1 inhibitor (an immunotherapy that helps your immune system fight cancer), and sometimes radiation—for colorectal cancer that has stopped responding to standard treatments. The goal is to see if this combination can slow or shrink your cancer.
Wuhan, HubeiAges 18–75 - NCT07639606Recruiting
Mobile therapy app for mood after recent stroke
This study tests whether using a smartphone or tablet app for cognitive behavioral therapy (a type of talk therapy you do on your device) can help with anxiety and depression in the first month after a stroke. The goal is to see if this convenient, at-home approach improves how you feel during early recovery.
New York, New YorkAges 18–79 - NCT07645898Recruiting
Glucose monitoring study of cornstarch in glycogen storage disease
This study uses a glucose monitor (a small sensor you wear) to measure how your blood sugar responds after eating raw cornstarch, a common treatment for glycogen storage disease type I. The goal is to understand how well cornstarch helps keep your blood sugar steady.
Naples, NapoliAges 18 years+
Hear when a new Bipolar Disorder I or II trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,351 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.