Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06374433Recruiting
How the brain learns: a brain stimulation study
This study explores how the brain learns and adapts (called brain plasticity) using a non-invasive brain stimulation technique. It may help understand learning and perception in healthy young adults.
MilanAges 18–35 - NCT06986967Recruiting
Comparing Blood Flow Methods During Aortic Arch Surgery
This study compares two methods of supplying blood to the brain during surgery on the main artery from the heart (aorta) and the aortic arch. It may help determine the safest way to protect the brain during cooling and surgery.
Durham, North CarolinaAges 18 years+ - NCT06243783Recruiting
Stress and Brain Energy: A Healthy Volunteer Study
This study looks at how stress affects your brain's energy use. It involves an MRI scan and is for healthy, right-handed adults aged 18–40.
ViennaAges 18–40 - NCT06142773Recruiting
Brain activity and breathing during MRI
This study looks at how brain activity relates to the depth of your breaths during an MRI scan while you are under anesthesia. It may help doctors better understand breathing control during surgery.
Toronto, OntarioAges 18 years+ - NCT06127667Recruiting
Balance, brain health, and aging
This study looks at how your brain and blood vessels work together to keep you balanced as you age. It may help researchers understand why some people stay steady on their feet and others don't.
Minneapolis, MinnesotaAges 21–95 - NCT06123182Recruiting
Guided future thinking for exercise and brain health
This study tests whether a technique called 'guided episodic future thinking' (imagining positive future events) can help you stick with a physical activity program and support healthy brain aging. You'll be asked to exercise on a stepper machine and have MRI scans and blood draws.
Kansas City, KansasAges 45–65 - NCT07221539Recruiting
Waking the brain with ultrasound during sedation
This study uses focused ultrasound to stimulate a deep brain region and see if it can help people wake up faster from anesthesia. Healthy volunteers will be sedated and monitored while the ultrasound is applied.
Ann Arbor, MichiganAges 18–40 - NCT06137339Recruiting
Daily avocado and cognition in older adults
This study tests whether eating one avocado daily for 6 months can help keep your thinking and memory sharp as you age. You must not currently eat many avocados or vegetables, and be willing to change your diet.
Kansas City, KansasAges 65–85 - NCT06108336Recruiting
How the cerebellum affects thinking and sequencing
This study uses MRI and TMS to understand how the cerebellum, a brain region, helps with cognitive sequencing—putting thoughts or actions in order. It may lead to better treatments for cognitive problems.
Baltimore, MarylandAges 18–50 - NCT07671950Recruiting
Deep brain stimulation for neuropathic dental pain
This trial studies whether deep brain stimulation (DBS) can help people with a type of nerve-related tooth pain called atypical odontalgia. It is for those who have not found relief from standard treatments like medications or injections.
Vancouver, British ColumbiaAges 19–80 - NCT07497347Recruiting
Amino acids and lifestyle for brain aging in older adults
This study tests whether taking a specific amino acid supplement, along with lifestyle changes, can help slow or improve brain aging in older adults who have mild depression. It aims to see if these nutrients can support brain health and mood.
BresciaAges 65–85 - NCT07400484Recruiting
N-CAD levels and brain function in children with autism
This study compares levels of a protein called N-CAD and brain function in children with autism spectrum disorder (ASD) versus typically developing children. It may help researchers understand how the brain works differently in autism.
Chongqing, Chongqing MunicipalityAges 3–5 - NCT07386769Recruiting
Brain activity during social interaction in opioid use
This study looks at how the brain works during social interactions in people who use opioids regularly. It may help researchers understand how opioid use affects the way you connect with others.
La Jolla, CaliforniaAges 18 years+ - NCT07346989Recruiting
Brain stimulation to improve function in frail older adults
This study uses a gentle, non-invasive brain stimulation technique (called transcranial direct current stimulation, or tDCS) to see if it can improve physical function and daily activities in older adults who are showing early signs of frailty. You will be asked to do some simple exercises and cognitive tasks while receiving or not receiving the stimulation.
Valencia, ValenciaAges 65–90 - NCT07267403Recruiting
Brain activity and sedation during anesthesia
This trial studies how stimulating a nerve in the wrist affects brain activity and sedation levels during propofol anesthesia. It may help improve care for right-handed patients having surgery.
BrusselsAges 18–81 - NCT07747181Recruiting
Brain stimulation and yoga for thinking skills in psychosis
This study tests whether combining brain stimulation with yoga can improve thinking and memory in people with psychosis. It may help with daily functioning and quality of life.
Hung Hom, KowloonAges 18–65 - NCT07748598Recruiting
Brain scan monitoring for HER2-positive breast cancer
This study is testing regular MRI brain scans to find any brain metastases early in people with HER2-positive breast cancer that has spread. It aims to see if early detection can help guide treatment and improve outcomes.
LiverpoolAges 16 years+ - NCT06224530Recruiting
Testing levetiracetam's effect on brain function in psychosis risk
This trial tests whether a single dose of levetiracetam, a medication that affects brain chemistry, can change brain function and thinking in people at risk for psychosis. The goal is to see if it might help prevent symptoms from worsening.
London, LondonAges 18–40 - NCT07434037Recruiting
Trust and the brain in Down syndrome and Fragile X
This study explores how people with Down syndrome or Fragile X syndrome learn to trust others. It uses simple tasks and a brain scan (MRI) to compare their responses with those of typically developing children and young adults.
BronAges 3–29 - NCT07535593RecruitingPhase 2/Phase 3
Electrical Acupoint Stimulation for Consciousness Disorders
This trial tests a non-invasive treatment called transcutaneous electrical acupoint stimulation (TEAS) to help people recover consciousness after severe brain injury. The treatment uses mild electrical pulses on specific points on the hands and may help improve awareness and responsiveness.
Xi'an, ShaanxiAges 18–80 - NCT07215910RecruitingPhase 3
Testing vorasidenib with temozolomide after radiation for advanced brain cancer
This trial tests whether adding the targeted drug vorasidenib to standard chemotherapy (temozolomide) after radiation helps people with a specific type of advanced brain cancer called IDH-mutant astrocytoma. It is for patients who have not had previous treatments like chemotherapy or radiation and whose tumors have certain genetic features.
Duarte, CaliforniaAges 12 years+ - NCT07050862Recruiting
Personalized brain stimulation to help veterans quit smoking
This study tests a personalized brain stimulation treatment to help veterans quit smoking. It uses magnetic pulses to target brain areas involved in addiction, which may reduce cravings and make it easier to stop.
Charleston, South CarolinaAges 18–70 - NCT07680439RecruitingPhase 2
CAR T cell therapy study for children with DIPG brain tumor
This trial tests a new CAR T cell therapy (BCB-276) for children and young adults with a type of brain tumor called DIPG. The therapy uses your own immune cells that are specially trained to attack the cancer.
Los Angeles, CaliforniaAges 1–26 - NCT03726359Recruiting
Targeted radiation for brain metastases using staged stereotactic treatment
This Phase 1 study tests a form of focused radiation given in stages to shrink larger brain metastases. It may help people whose tumors are in the brain but not suited to whole-brain radiation alone, while also checking safety and how well the treatment can be delivered.
The Bronx, New YorkAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.