Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06779487Recruiting
Predicting memory changes from brain radiation
This study looks for biomarkers in your blood that might predict how radiation treatment affects brain function. The goal is to understand and possibly reduce cognitive side effects.
Mumbai, MaharashtraAges 5–39 - NCT06781762Recruiting
Breast cancer hormone therapy and its effects on heart and brain
This study looks at how starting a common hormone therapy for breast cancer (aromatase inhibitors) affects your heart and brain health over the short term. It compares women starting this treatment to healthy women who are not on the therapy.
Toronto, OntarioAges Any age - NCT06782464Recruiting
Freezing nerves for shoulder pain after stroke or brain injury
This trial tests if freezing certain nerves in the upper arm (cryoneurolysis) works as well as standard care for reducing shoulder pain and muscle tightness after a stroke or brain injury. It aims to improve function and ease caregiving tasks.
LuxembourgAges 18 years+ - NCT06784388RecruitingEarly Phase 1
Deep brain stimulation for tough-to-treat depression
This early trial tests a personalized deep brain stimulation (DBS) approach for people with major depression that hasn't improved with at least two different antidepressants. DBS uses small electrodes placed in the brain to adjust mood-related circuits.
Hangzhou, ZhejiangAges 18–70 - NCT06789666Recruiting
Digital art therapy for young cancer survivors
This trial is testing a digital art therapy program designed to help young adults who survived childhood cancer feel better emotionally. You'll use an app to create art and connect with others, all from home.
Chapel Hill, North CarolinaAges 18–25 - NCT06791837Recruiting
Brain blood flow and lactate in obesity study
This study looks at how blood flow and lactate (a chemical your body makes) in the brain differ between people with a healthy weight and those with obesity. It may help researchers understand how weight affects brain function.
Columbia, MissouriAges 18–45 - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT06796725Recruiting
Study of TMS for migraine guided by brain imaging
This study tests whether repetitive transcranial magnetic stimulation (rTMS), guided by magnetoencephalography (MEG), can help people with frequent migraines or tension-type headaches. If you have headaches 15 or more days per month, this treatment might reduce your pain.
ShanghaiAges 15–50 - NCT06797661Recruiting
Brain lesion blood flow study before surgery
This study looks at how blood flow in the brain changes when there is a mass that can be removed with surgery. You would join before any treatment, which helps doctors understand the link between the brain lesion and blood vessel function.
BrusselsAges 18–90 - NCT06797752Recruiting
Stellate ganglion block and retina blood flow study
This trial looks at how a nerve block (stellate ganglion block) affects blood flow in the retina. It may help people who already get this block for conditions like complex regional pain syndrome understand eye effects.
Dallas, TexasAges 18 years+ - NCT06798740Recruiting
Study of brain aneurysm treatment with Sugita clipping devices
This study tracks people with brain aneurysms treated with a Sugita clipping device, watching how well it works and how they recover. It includes both ruptured and unruptured aneurysms, and follows standard care.
EssenAges 18 years+ - NCT06799429Recruiting
Exercise program for people with memory challenges
This trial tests whether a structured exercise program can help people with mild to moderate memory or thinking problems. You'll work with a trainer to improve your fitness and brain health.
Columbia, South CarolinaAges 18 years+ - NCT06810310RecruitingPhase 2
Psilocybin for motivation in opioid use disorder
This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) can help people with opioid use disorder stay motivated in recovery. It uses brain scans to see how psilocybin affects brain areas linked to motivation.
Philadelphia, PennsylvaniaAges 18–60 - NCT06810544RecruitingPhase 1/Phase 2
Study of TNG456 for tumors with MTAP loss
This trial tests a new drug called TNG456, alone or with another drug (abemaciclib), for people whose tumors have lost the MTAP gene. It aims to see if the combination can shrink tumors or slow their growth.
Scottsdale, ArizonaAges 18 years+ - NCT06815237RecruitingPhase 2/Phase 3
Ketone supplement and alcohol effects on brain metabolism
This study looks at how a ketone supplement and alcohol affect your brain's metabolism. You will be asked to visit the lab, have an MRI, and possibly take the supplement or drink alcohol.
Philadelphia, PennsylvaniaAges 21–65 - NCT06815432RecruitingPhase 1
CAR T cells for recurrent glioblastoma that makes GPC3
This trial tests a treatment made from your own immune cells, called CAR T cells, which are engineered to find and attack brain tumor cells that have a marker called GPC3. It is for patients whose glioblastoma has come back and who are already scheduled to have another surgery to remove the tumor.
Houston, TexasAges 21–70 - NCT06819657Recruiting
Remote ischemic conditioning after aneurysm surgery
This trial tests a safe, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff on your leg) to see if it helps brain recovery after aneurysm surgery. It might reduce secondary damage and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06821568Recruiting
Home brain stimulation for memory and walking concerns
This study tests if a gentle brain-stimulation device used at home can help older adults who have both memory worries and slower walking. A study partner will help you use the device.
Roslindale, MassachusettsAges 65–90 - NCT06823193Recruiting
How self-processing impacts mental time travel
This study explores how thinking about yourself affects your ability to imagine past or future events. It may help researchers understand how the brain connects self-awareness to memory and planning.
Castel Goffredo, MantovaAges 40–80 - NCT06823492Recruiting
Early life and brain study
This study looks at how your early life experiences may affect your brain and behavior. You would visit the University of Manchester for assessments and help researchers understand these connections.
ManchesterAges 18–25 - NCT06826287Recruiting
7T MRI study of action watching in cerebral palsy
This study uses a very powerful 7T MRI scanner to look at how your brain responds when you watch actions. It may help doctors understand brain injury in people with cerebral palsy.
Calambrone, PISAAges 11–40 - NCT06826781Recruiting
Testing a neck collar's effect on brain blood flow during exercise
This study tests whether a special collar worn around the neck can help control blood flow to the brain during exercise. If you are a healthy young adult, this trial may help researchers understand how the collar affects brain health.
Cambridge, MassachusettsAges 18–30 - NCT06828107Recruiting
Testing a device to detect traumatic brain injury
This study tests a new device called SENSE to see if it can detect traumatic brain injury (TBI) quickly. You may qualify if you have a TBI with bleeding seen on a CT scan, or if you are a healthy volunteer without brain problems.
Gainesville, FloridaAges 22 years+ - NCT06828341RecruitingEarly Phase 1
CAR-T cell therapy for recurrent brain glioma
This trial tests a new type of immune cell therapy (CAR-T cells) made from donor cells, designed to target tumors with a specific marker called CD70. It is for people whose brain glioma has come back or hasn't responded to standard treatments.
China, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.