Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06370845RecruitingEarly Phase 1
Smell test to find natural odor in spinal fluid
This study investigates whether a natural smell can be detected in the fluid around your brain and spine (cerebrospinal fluid) after you sniff it. It aims to understand how smells enter the brain in people with different body weights who are already scheduled for a routine spinal tap.
BaselAges 18–60 - NCT06377371RecruitingPhase 4
Intraoperative tracing of meningioma with copper-64 DOTATATE
This trial tests a special imaging agent called [Cu64]DOTATATE that helps surgeons see meningioma tumors during surgery. It may make tumor removal more complete and safer.
New York, New YorkAges 18–99 - NCT06375265Recruiting
Sleep improvement program for older surgery patients
This trial tests a digital sleep improvement program for older adults who are about to have knee or hip replacement surgery. It aims to help you sleep better before and after surgery, which may improve your brain health and recovery.
Boston, MassachusettsAges 65 years+ - NCT06339398Recruiting
Exercise dose and brain health in Parkinson's
This study looks at how different amounts of physical exercise affect brain chemicals, movement symptoms, and brain connections in people with Parkinson's disease. You would walk and do exercises while researchers track changes over time.
Cassino, FrosinoneAges 30–80 - NCT06355778Recruiting
Brain and Opioid Use Study
This study uses brain scans to understand how adversity affects opioid use and recovery. It compares people with opioid use disorder on buprenorphine, people taking buprenorphine for chronic pain, and healthy volunteers.
Ann Arbor, MichiganAges 18–55 - NCT06352710Recruiting
Tracking recovery after brain or spine surgery
This study uses a smartphone app to track how you recover after brain or spine surgery. It helps doctors understand how side effects affect your daily life, so they can improve care.
Sankt Gallen, St.GallenAges 18 years+ - NCT06351098Recruiting
Sleep, memory, and brain development in napping toddlers
This study follows healthy toddlers who nap regularly to understand how sleep helps memory and brain growth. It uses sleep diaries, activity monitors, and optional brain scans (MRI) to track changes as children grow out of naps.
College Park, MarylandAges 3–5 - NCT06345963Recruiting
Brain stimulation to improve connectivity in schizophrenia
This study tests if brain stimulation can improve how different brain regions communicate in people with schizophrenia. It may help improve thinking and daily function.
Houston, TexasAges 18–60 - NCT06324786Recruiting
Brain training to reduce alcohol, cannabis, and tobacco use
This study tests whether a type of brain training called neurofeedback can help people reduce their use of alcohol, cannabis, and cigarettes. If you're an adult who uses all three heavily and have no other mental health conditions, you may be eligible.
Phoenix, ArizonaAges 18 years+ - NCT06332963Recruiting
Trial on body image and internal body signals in anorexia
This study explores how the brain senses internal body signals linked to body image in anorexia. It may help develop better treatments by understanding these connections.
Tulsa, OklahomaAges 13–50 - NCT06329245Recruiting
Tracking social skills and brain growth in infants at risk for autism
This study looks at how social behaviors and brain connections develop in infants who have a higher or lower chance of developing autism. It helps doctors understand early signs and may lead to better support for children and families.
ShanghaiAges birth–1.5 years - NCT06322212RecruitingEarly Phase 1
Type 2 diabetes and brain blood barrier study
This study tests if a treatment can improve the blood-brain barrier in adults with type 2 diabetes. It uses MRI scans to see changes and may help protect brain function.
Los Angeles, CaliforniaAges 40–65 - NCT06308952RecruitingPhase 4
Atorvastatin before flow diverter for brain aneurysms
This trial tests whether taking atorvastatin before a flow diverter procedure can prevent strokes or other brain events in people with unruptured brain aneurysms. It may help reduce complications from the treatment.
Guangzhou, GuangdongAges 18–75 - NCT06312631Recruiting
Home glove helps stroke survivors use their arm
This study tests a home-use glove (SaeboGlove®) that may help people who had a stroke grip and hold objects with their hand. It looks at how using the glove affects arm function and what factors help people stick with the program.
ToulouseAges 18–90 - NCT05239780Recruiting
Brain stimulation study for adults with depression
This study uses an invasive approach (placement of brain monitoring/stimulation) to better understand how the brain processes reward in depression. It may help researchers develop more targeted treatments in the future.
New York, New YorkAges 18–80 - NCT05389787Recruiting
Brain stimulation to improve thinking in schizophrenia
This pilot study tests whether stimulating the cerebellum (a part of the brain) using TMS can improve brain function and thinking in people with schizophrenia. If you qualify, you may receive TMS and undergo brain/cognitive assessments to see whether it helps.
New York, New YorkAges 18–60 - NCT05866432RecruitingPhase 2
Dato-DXd for triple-negative breast cancer brain metastases
This trial studies Dato-DXd (an antibody-drug medicine) in people with triple-negative breast cancer that has spread to the brain. It aims to see how well it controls brain tumors when they are newly found or growing after other treatments.
Vienna, State of ViennaAges 18–100 - NCT06286800Recruiting
Personalized brain stimulation for stroke recovery
This study tests a personalized, non-invasive brain stimulation treatment called transcranial direct current stimulation (tDCS) to help improve movement in people who have had a stroke that affects one side of the body. It aims to see if this gentle electrical stimulation can boost recovery of arm and hand function.
Houston, TexasAges 18–80 - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT02509442Recruiting
Testing brain responses during awake brain surgery
This trial measures how the brain reacts to small electrical stimulation during an awake surgery for a specific type of brain tumor. It may help surgeons better plan and improve care for people having their first surgery for this tumor type.
MontpellierAges 30–50 - NCT03857529Recruiting
Rehab training for stroke arm control using brain and hand stimulation
This study tests whether non-invasive brain stimulation plus a hand/arm electrical stimulation device can improve how well your stroke-affected arm and hand move during therapy tasks. You would take part in screening and then receive these combined rehab approaches to see if motor control improves.
Cleveland, OhioAges 21 years+ - NCT06270290Recruiting
Concussions and contact sports in RBD patients versus controls
This trial looks at whether people with REM sleep behavior disorder (RBD) have more concussions or contact sports history than people without RBD, to see if head injuries might be linked to the condition.
London, LondonAges 50 years+ - NCT06248606RecruitingPhase 2
Adagrasib with brain radiation for KRAS G12C lung cancer with brain mets
This study tests a targeted pill (adagrasib) combined with focused radiation to the brain (SRS) for people with KRAS G12C-mutated lung cancer that has spread to the brain. The goal is to see if this combination can control brain tumors while treating the rest of the body.
Columbus, OhioAges 18 years+ - NCT06243783Recruiting
Stress and Brain Energy: A Healthy Volunteer Study
This study looks at how stress affects your brain's energy use. It involves an MRI scan and is for healthy, right-handed adults aged 18–40.
ViennaAges 18–40
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.