Clinical trials · Florida
Breast cancer clinical trials in Florida
We’re tracking 213 recruiting breast cancer studies with a site in Florida — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT05867251RecruitingPhase 1/Phase 2
AVZO-021 for advanced breast and ovarian cancers
This early-stage study tests AVZO-021, a new anti-cancer medicine, in people with advanced solid tumors like specific types of breast and ovarian (or related) cancers. It’s meant to find the safest dose and look for signs the medicine can shrink tumors, especially in cancers with certain gene changes.
Tampa, FloridaAges 18 years+ - NCT05868226RecruitingPhase 1
Early cancer drug study for adults with advanced tumors
This Phase 1 study tests early (first-in-program) cancer medicines in people whose cancer has not been adequately controlled. It helps researchers learn the safest dose and early signs of whether the treatment may work for different tumor types and treatments.
Tampa, FloridaAges 18 years+ - NCT05950945RecruitingPhase 3
Trastuzumab deruxtecan for HER2-low metastatic breast cancer
This trial tests a targeted antibody-drug medicine (trastuzumab deruxtecan, T-DXd) in people with metastatic breast cancer that is HER2-low or HER2 IHC 0. It may help by treating tumors that haven’t previously received anti-HER2 treatment in the metastatic setting.
Tampa, FloridaAges 18 years+ - NCT05959291Recruiting
Stopping long-term anti-HER2 therapy in stable metastatic breast cancer
This study asks whether some people with HER2-positive metastatic breast cancer who have been stable for a long time can safely stop their ongoing (maintenance) anti-HER2 treatment. It also uses blood testing and close imaging follow-up to watch for early signs that treatment needs to restart.
Miami, FloridaAges 18 years+ - NCT05983432RecruitingPhase 1
Study of BL-B01D1 for advanced lung and other solid tumors
This trial tests an experimental drug called BL-B01D1 for people with several types of advanced solid tumors, especially non-small cell lung cancer and breast cancer. It's designed for those whose cancer has continued to grow after standard treatments.
Miami, FloridaAges 18 years+ - NCT06072612RecruitingPhase 3
Bria-IMT plus CPI vs standard care for advanced breast cancer
This trial tests a new combination of two immunotherapy drugs (Bria-IMT and a checkpoint inhibitor) against your doctor's choice of standard treatments. It is for people with advanced breast cancer that has spread and who have already tried several prior therapies.
Aventura, FloridaAges 18 years+ - NCT06075810RecruitingPhase 1
Oral MBQ-167 for advanced breast cancer
This trial tests an experimental oral drug, MBQ-167, for people with advanced breast cancer who have tried other treatments or have no standard options left. The goal is to see if the drug can help slow or stop the cancer.
Sarasota, FloridaAges 21 years+ - NCT06112613Recruiting
Mobile health to help with breast cancer pill-taking
This study uses text messages to help people with metastatic breast cancer remember to take their daily pills and asks about any missed doses. It aims to improve how well patients stick to their CDK4/6 inhibitor medication.
Fort Lauderdale, FloridaAges 18 years+ - NCT06120283RecruitingPhase 1
Testing a new drug for breast cancer and other solid tumors
This trial tests a new oral drug (BGB-43395) alone or with other treatments for people with advanced breast cancer or other solid tumors that depend on CDK4. It aims to find safe doses and see if the drug helps shrink tumors or slow growth.
Lake Mary, FloridaAges 18 years+ - NCT06153836RecruitingPhase 2
Restoring nipple sensation after mastectomy
This trial is testing a surgical technique to reconnect nerves in the nipple and areola after a mastectomy, aiming to restore feeling. It is for women with breast cancer who are having a nipple-sparing mastectomy with implant reconstruction.
Jacksonville, FloridaAges 18 years+ - NCT06238921RecruitingPhase 1/Phase 2
Study of two drugs and radiation for triple-negative breast cancer that spread to the brain
This trial tests adding the drugs sacituzumab govitecan and zimberelimab to targeted radiation therapy for people with triple-negative breast cancer that has spread to the brain. The goal is to see if this combination helps control the cancer longer.
Tampa, FloridaAges 18 years+ - NCT06239194RecruitingPhase 1/Phase 2
MdX2001 for advanced solid tumors
This trial tests a new drug, MDX2001, for people with advanced solid tumors that have spread. The study aims to find the best dose and see how well it works.
Miami, FloridaAges 18 years+ - NCT06253871RecruitingPhase 1
Study of IAM1363 for HER2 Cancers
This trial tests a new oral drug called IAM1363 for people with HER2-altered cancers that have stopped responding to previous treatments. The goal is to see if the drug is safe and how well it works against these cancers.
St. Petersburg, FloridaAges 18 years+ - NCT06327490RecruitingPhase 2
ICG-guided vs. traditional lymphatic drainage for breast cancer surgery
This trial compares a new imaging method (ICG) to the standard method for manual lymphatic drainage during breast cancer surgery. It aims to reduce swelling in the arm after lymph node removal.
Gainesville, FloridaAges 18–99 - NCT06388122Recruiting
Blood test study for HR+ breast cancer treatment monitoring
This study looks at a blood test (DiviTum TKa) to see how well it measures treatment response in people with hormone receptor-positive (HR+) breast cancer that has spread. The test may help doctors know if a treatment is working.
Jacksonville, FloridaAges 18 years+ - NCT06395519RecruitingPhase 1/Phase 2
Study of ETX-19477 for advanced solid tumors
This trial tests an experimental drug called ETX-19477 for people with advanced solid tumors that have stopped responding to other treatments. It aims to see if the drug is safe and effective, especially for those with certain genetic changes (BRCA2 mutations).
Jacksonville, FloridaAges 18 years+ - NCT06401889Recruiting
Skin care program for breast cancer survivors on hormone therapy
This study tests whether a skin care program can improve the appearance of your skin and your quality of life while you take an aromatase inhibitor (a hormone therapy) after breast cancer treatment. It is designed for women who are starting this type of therapy for the first time.
Jacksonville, FloridaAges 18 years+ - NCT07578571RecruitingPhase 1
Testing a New Cancer Treatment Called IM-1617
This is an early-stage study testing a new drug (IM-1617) for advanced solid cancers that have not responded to standard treatments. The drug combines an antibody with a cancer-killing agent and may help people whose cancer has progressed despite prior therapy.
Sarasota, FloridaAges 18 years+ - NCT06512350Recruiting
Breath test for breast cancer patterns
This study is testing whether a simple breath test can help find patterns linked to breast cancer. If you are scheduled for a breast biopsy or MRI, you may be eligible to participate.
Jacksonville, FloridaAges 40–74 - NCT06545331RecruitingPhase 1
A study of XB010 for advanced solid tumors
This trial tests an investigational drug called XB010 for people with solid tumors that have spread or cannot be removed by surgery. It aims to see if XB010 is safe and effective for several cancer types, including lung, breast, head and neck, and esophageal cancers.
Orlando, FloridaAges 18 years+ - NCT06568692RecruitingPhase 2
Study of PCS6422 with capecitabine for advanced breast cancer
This trial tests a new drug combination (PCS6422 plus capecitabine) for people with advanced or metastatic breast cancer that has not responded to other treatments. The goal is to see if adding PCS6422 can make the chemotherapy work better.
Tampa, FloridaAges 18 years+ - NCT06577987RecruitingPhase 1
Study of CID-078 for advanced solid tumors
This trial tests an experimental drug called CID-078 for people with advanced solid tumors that have stopped responding to other treatments. It aims to find the right dose and see if the drug can shrink tumors.
Sarasota, FloridaAges 12 years+ - NCT06586957RecruitingPhase 1
Study of NKT3964 for advanced solid tumors
This trial is testing an experimental oral drug called NKT3964 for people with advanced solid tumors that have stopped responding to standard treatments. The drug works by blocking a protein called CDK2, which some cancers need to grow.
Lake Mary, FloridaAges 18 years+ - NCT06625775RecruitingPhase 1
Study of BBO-10203 for advanced solid tumors
This trial tests a new drug called BBO-10203, alone or combined with other cancer treatments, for people with certain advanced breast, colorectal, or lung cancers. It aims to see if the drug is safe and effective.
Tampa, FloridaAges 18 years+
Breast cancer trials by city in Florida
Where these studies are running in Florida
Institutions with a site for the recruiting breast cancer studies listed above.
- Florida Cancer Specialists & Research Institute · 6 studies
- Mayo Clinic · 6 studies
- H. Lee Moffitt Cancer Center and Research Institute · 5 studies
- University of Miami · 5 studies
- AdventHealth Orlando · 2 studies
- Sarah Cannon Research Institute · 2 studies
- AP Medical Research
- Comprehensive Hematology Oncology
What taking part in a breast cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Breast cancer trials in other states
Common questions
- Are there breast cancer clinical trials in Florida?
- Yes. We're currently tracking 213 recruiting breast cancer studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a breast cancer study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New breast cancer studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.