Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,249 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06357182RecruitingPhase 1
New drug combo for AML patients who can't have strong chemo
This trial tests a new drug combination (iadademstat plus azacitidine and venetoclax) for people with newly diagnosed AML who cannot have or do not want standard intensive chemotherapy. The goal is to see if adding iadademstat makes the treatment work better.
Portland, OregonAges 18 years+ - NCT06507618RecruitingPhase 3
Pre-surgery hormone therapy to guide radiation decisions for breast cancer
This trial tests whether taking hormone therapy for 3 months before breast-conserving surgery can help doctors decide if radiation is right for you. It is for women aged 65 and older with a common type of breast cancer that is hormone receptor-positive and HER2-negative.
New Haven, ConnecticutAges 65 years+ - NCT06905002Recruiting
Improving access to cancer clinical trials
This study tests whether a nurse navigator can help more people learn about and enroll in cancer clinical trials. It focuses on patients and health care professionals in Thunder Bay and Winnipeg.
Thunder Bay, OntarioAges Any age - NCT06794086RecruitingPhase 3
SBRT and immunotherapy for colorectal cancer liver metastases
This trial combines targeted radiation (SBRT) with an immunotherapy drug (PD-1 inhibitor) to treat colorectal cancer that has spread to the liver and can't be removed by surgery. It aims to help shrink or control tumors in patients whose cancer has a normal DNA repair system (pMMR/MSS).
Guangzhou, GuangdongAges 18–75 - NCT06103838RecruitingPhase 2
Fluciclovine PET/CT scan for multiple myeloma
This trial tests whether a special PET/CT scan (using fluciclovine, a radioactive tracer) can more clearly see multiple myeloma in the body. It may help doctors evaluate the extent of the disease and guide treatment decisions.
Bethesda, MarylandAges 18–120 - NCT06990659Recruiting
Outpatient vs. Inpatient Liver Cancer Treatment Study
This study compares having your liver cancer treatment (TACE or TARE) as an outpatient versus staying in the hospital overnight. It's for people with primary liver cancer whose liver and kidney function are good enough and who can safely go home the same day with support.
AmiensAges 18 years+ - NCT05361837Recruiting
Nerve block with sedation for breast surgery comfort
This trial tests if adding a numbing injection (serratus anterior plane block) with a calming medicine (dexmedetomidine) helps reduce pain during and after breast removal surgery.
Cairo, Cairo GovernorateAges 18–65 - NCT07513389RecruitingPhase 2
HPV throat cancer trial skipping radiation with blood tests
This study tests whether patients with a specific type of HPV-positive throat cancer can safely skip radiation after surgery by using blood tests to monitor for cancer recurrence. The goal is to reduce side effects while keeping patients cancer-free.
Charleston, South CarolinaAges 18 years+ - NCT07493447RecruitingEarly Phase 1
Imaging dye to help see brain tumors during surgery
This study tests a special dye (panitumumab-IRDye800) that helps surgeons see brain lesions more clearly during surgery. The dye attaches to a protein on cancer cells and lights up under a special camera, which may help remove more tumor safely.
Nashville, TennesseeAges 18 years+ - NCT03226704Enrolling by invitation
Leukapheresis to prepare CAR cell therapy
This trial collects white blood cells through a procedure called leukapheresis to help make CAR or other adoptive cell therapies. It’s for people with certain cancers who are not in remission (or are at high risk of relapse) and can meet health and lab requirements.
Bethesda, MarylandAges 3–65 - NCT02688517Recruiting
Tests tumor genomics using blood and stored tissue
This study looks at the genetic information (DNA) from your blood and from saved tumor tissue to better understand certain cancers, especially rare cancers with a poor outlook. It may help researchers learn why these cancers behave the way they do and guide future treatments.
Brick, New JerseyAges 1 year+ - NCT02436941Enrolling by invitation
Radiation treatment patient registry for eligible tumor conditions
This registry collects information from people who have conditions that may be treated with radiation therapy (proton or standard X-ray radiation). It helps the clinic better understand patients’ care and outcomes, and joining requires signing consent.
Ages Up to 99 years - NCT02471170Enrolling by invitation
Taking blood samples for pancreatic and related cancer research
This study asks people receiving care at the University of Pennsylvania Hospital to provide samples that can help researchers study tumor material. If you have pancreatic disease—or you’re getting care for something else (like a routine colonoscopy)—your samples may be used to compare findings and improve future research.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02526797Enrolling by invitation
MRI scan study for men on active surveillance
This trial tests how a special MRI scan (with multiple measurements) may help men with low-risk prostate cancer who are monitoring it closely instead of treating right away. It may help doctors better understand the cancer’s status during active surveillance.
HerlevAges 18–75 - NCT02473757Enrolling by invitation
Follow-up program for adults previously treated with CAR T
This is a follow-up study for people age 18 or older who previously took part in a CAR T-cell gene therapy trial. It helps researchers check your health over time after that treatment and supports long-term safety and outcomes tracking.
Bethesda, MarylandAges 18 years+ - NCT02091518Enrolling by invitation
MRI scanning methods study to improve image quality
This study tests how to take and analyze MRI scans in a safer, more useful way. If you can have an MRI comfortably and safely, your scans may help improve imaging methods for future patients.
New York, New YorkAges 18 years+ - NCT02081755Enrolling by invitationPhase 4
Everolimus after liver transplant to lower liver cancer return
This trial studies whether everolimus, a transplant medicine, can safely reduce the chance that liver cancer comes back after liver transplant. It compares how well the treatment works while carefully monitoring side effects and safety.
San Francisco, CaliforniaAges 18 years+ - NCT00588068Recruiting
Study genes in neuroblastic tumors and compare with outcomes
This study looks at the tumor’s molecular (genetic) features in people with neuroblastic tumors to see how those features relate to clinical outcomes. If you are treated with naxitamab as part of standard care, you may be eligible for the tumor/biomarker (test results) portion of the research.
New York, New YorkAges Any age - NCT00900497Enrolling by invitationPhase 1/Phase 2
Donor white blood cells to treat solid tumors
This Phase 1/2 study tests whether donated white blood cells (granulocytes) from healthy donors can help treat solid cancers that cannot be cured or have stopped responding to standard treatments. The goal is to see safety first, and then whether the treatment can shrink or control tumors.
Boynton Beach, FloridaAges 18 years+ - NCT00501826RecruitingPhase 2
Check nelarabine plus chemotherapy for T-cell blood cancers
This trial tests a combination of chemotherapy with nelarabine in people with T-cell acute lymphoblastic leukemia (ALL) or T-cell lymphoblastic lymphoma. It may help by improving remission in newly diagnosed or certain previously treated patients whose disease did not respond after one initial treatment.
Houston, TexasAges Any age - NCT00923026Enrolling by invitation
Follow-up for adults previously treated in NCI surgery studies
This study asks people age 18+ who were previously treated on certain NCI Surgery Branch (NCI-SB) studies to come back for follow-up. It helps researchers understand how patients do over time after those earlier treatments, including some gene therapy studies.
Bethesda, MarylandAges 18 years+ - NCT00102544Enrolling by invitation
Tracking Devices to Find Abnormalities During Medical Procedures
This study tests technology that uses imaging scans to help doctors locate and reach abnormalities during surgical or interventional procedures. The goal is to make these image-guided procedures more accurate and safer for patients.
Bethesda, MarylandAges 18–120 - NCT00107289RecruitingPhase 2
MIBG radioactive iodine treatment for hard-to-treat childhood tumors
This trial studies a radioactive medicine called iodine I-131 MIBG to shrink tumors that take up MIBG. It may help people whose neuroblastoma or malignant pheochromocytoma/paraganglioma has come back, progressed, or not responded to standard treatment.
New York, New YorkAges 1 year+ - NCT01205815Recruiting
Use and storage of leftover melanoma tissue for future testing
This study collects and stores leftover melanoma tissue (and sometimes blood) for future research and testing. If the trial uses your stored samples to help match treatments, it could support better care planning over time.
Nashville, TennesseeAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,249 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.