Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,042 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03796559Recruiting
Magnetic marker helps find breast cancer lymph nodes
This study uses a tiny magnetic marker (called Magseed) placed in a breast cancer–affected underarm lymph node, then tracks whether surgeons can find and remove the correct nodes after chemotherapy. It may help reduce the chance of missing cancer in the underarm while aiming for more accurate surgery.
Houston, TexasAges 18 years+ - NCT03854110RecruitingPhase 1
Testing a new drug for ovarian cancer that resists platinum chemo
This trial studies a new drug, misetionamide, given alone or with gemcitabine, for people with ovarian, fallopian tube, or primary peritoneal cancer that no longer responds to platinum-based chemotherapy. The goal is to see if the drug is safe and if it can help shrink or control the cancer.
Chicago, IllinoisAges 18 years+ - NCT03721068RecruitingPhase 1
CAR T-cell treatment for hard-to-treat childhood tumors
This Phase 1 study tests an experimental CAR T-cell treatment that targets GD2, with added immune-boosting and safety features, for children with relapsed or refractory neuroblastoma or osteosarcoma. It’s designed to see if the treatment is safe and can shrink these cancers when standard therapy hasn’t worked.
Atlanta, GeorgiaAges 1.5 years+ - NCT03830151RecruitingPhase 1
C-13 pyruvate MRI to help diagnose brain gliomas
This early-phase study tests a special MRI scan using C-13 pyruvate to help identify and understand gliomas (a type of brain tumor) in people with brain tumors going to surgery or biopsy. It may help doctors see tumor signals better before or around the time of your procedure.
Houston, TexasAges 19 years+ - NCT03785288RecruitingPhase 3
Testing different schedules of vaginal radiation after hysterectomy
This trial compares different “fractionation” schedules (how often and how many treatments) of vaginal brachytherapy radiation given after surgery for certain early-stage endometrial cancer. It may help find a plan that works well while aiming to control side effects.
Baltimore, MarylandAges 18 years+ - NCT03789721Recruiting
ALD registry study for patients and families in the U.S.
This study builds a national registry to better understand adrenoleukodystrophy (ALD) in patients and families. You may help researchers learn how ALD affects people over time and improve future care.
Minneapolis, MinnesotaAges Any age - NCT03791073Recruiting
Looking for New Markers in Pancreatic Cancer
This study looks for new markers in the blood or tissue of people with a pancreatic mass that might be cancer. It uses samples from a routine biopsy or surgery to help doctors learn more about the disease.
Montpellier, MontpellierAges 18 years+ - NCT03873064Recruiting
Weight and quality of life in cancer patients
This study looks at how body weight (measured as body mass index, or BMI) relates to quality of life in people with solid tumors. You would fill out questionnaires about how you feel, and the results may help doctors better support patients.
RomeAges 18 years+ - NCT03841799Recruiting
Study of gut bacteria and immune changes in colon tissue
This study looks at how gut bacteria and immune activity differ in normal, pre-cancer, and cancer colon tissue. It may help researchers understand what changes in the body are linked to colon growth and how they could be targeted in the future.
Lyon, LyonAges 18 years+ - NCT03750513RecruitingPhase 1
Tested improved radiation targeting for children with ependymoma
This early-phase study tests a more precisely targeted type of radiation for children with ependymoma, aiming to treat the brain tumor more accurately. It may help reduce how much healthy tissue gets radiation, and researchers are checking safety and best dosing.
Boston, MassachusettsAges Up to 22 years - NCT03830320RecruitingPhase 1
PET scan to look for blood clots in the heart or lungs
This Phase 1 study uses a PET scan to detect blood clots (thrombosis) in specific groups of people. It’s testing how well the scan can find clots and how it should be timed with other heart or illness tests.
Boston, MassachusettsAges 18–85 - NCT03874052RecruitingPhase 1
Ruxolitinib plus venetoclax and azacitidine for relapsed AML
This early-phase study tests a combination of ruxolitinib with venetoclax, with or without azacitidine, for adults whose acute myeloid leukemia (AML) has come back or does not respond to treatment. It may help by stopping cancer cells from growing and improving blood counts, with the exact plan guided by the study arm you’re assigned to.
Columbus, OhioAges 18 years+ - NCT03851458Enrolling by invitationPhase 2
Spanish coaching for healthier food choices for weight
This Phase 2 study tests a program (with food guidance, text messages, and check-ins) to help people eat more healthfully. It is designed for adults who are overweight or obese and can speak Spanish (with some separate tracks for different groups).
New York, New YorkAges 18 years+ - NCT03810339RecruitingPhase 2
Check a POLE/POLD cancer drug for non–MSI-high tumors
This Phase 2 trial studies toripalimab (JS001), given alone, in people whose tumors have specific POLE or POLD gene mutations but do not have MSI-H/dMMR. If it works, it may help shrink or control advanced solid tumors that have not responded to standard treatment.
Guangzhou, GuangdongAges 18–75 - NCT03803787RecruitingPhase 2
Inhaled steroid to prevent lung inflammation during cancer treatment
This trial tests whether breathing in steroid medicine before and during radiation can lower how often and how badly “radiation lung inflammation” (radiation pneumonitis) happens in people with lung cancer. If you qualify, it may help protect your lungs while you receive radiation with chemotherapy or targeted therapy.
Mexico CityAges 18–75 - NCT03748485Recruiting
Chemo after surgery for certain stage III colon cancer
This trial studies whether adding chemotherapy after surgery helps people with colon cancer that was diagnosed before surgery as stage III and later found to be without certain high-risk features. It may help lower the chance the cancer comes back, but you must meet specific surgery and health criteria.
Guangzhou, GuangdongAges 18–75 - NCT03784924Recruiting
Prostate MRI study to find blood and urine cancer signals
This study enrolls men who may have prostate cancer but do not yet have a diagnosis. It uses prostate MRI along with blood and urine tests to see if specific signals can help identify prostate cancer sooner.
Ann Arbor, MichiganAges 18 years+ - NCT03872661RecruitingPhase 2
New lung cancer medicines before surgery for unresectable stage III
This Phase 2 trial tests a combination of IBI308 plus bevacizumab and pemetrexed/carboplatin given before surgery, aiming to shrink or control unresectable stage III non-small cell lung cancer. It may help some people become eligible for surgery and improve outcomes, while also testing safety and effectiveness.
Guangzhou, GuangdongAges 18–75 - NCT03550391RecruitingPhase 3
Surgery-like brain radiation vs avoiding the memory center
This trial compares two ways of giving radiation to the brain for people with 5 or more brain metastases: focused stereotactic radiosurgery, or a whole-brain approach that tries to spare the memory area (with memantine). It aims to see which method better protects thinking and memory while still treating the tumors.
Tucson, ArizonaAges 18 years+ - NCT03670966RecruitingPhase 1/Phase 2
Targeted iodine therapy, then donor transplant for hard leukemias
This trial tests an antibody-linked radioactive iodine treatment, followed by a donor stem cell transplant, for people with relapsed or refractory high-risk acute leukemia or certain MDS. It may help patients by targeting leukemia cells and then using a new immune system to control the disease.
Seattle, WashingtonAges 18–75 - NCT03562273Recruiting
GammaPod planning study for breast cancer quality of life
This study looks at how GammaPod radiation planning after a lumpectomy affects quality of life and comfort. Your doctors will use imaging and a structured plan to help predict outcomes and refine care.
Bel Air, MarylandAges 18 years+ - NCT03579875RecruitingPhase 2
Testing an inherited bone marrow transplant approach for rare blood disorders
This Phase 2 study tests a special “T-cell depleted” transplant plan for people with inherited bone marrow failure disorders (Fanconi anemia or T-Beta-thalassemia—or “TBD”). It may help restore healthy blood production while lowering the chance of certain transplant complications.
Minneapolis, MinnesotaAges Up to 65 years - NCT03683680Recruiting
Collecting pleural tissue samples to study mesothelioma markers
This study collects tissue samples (from the lining around the lung) from adults with malignant pleural mesothelioma. Researchers will use these samples to check whether certain test markers can predict how the disease may behave, which could guide treatment decisions in the future.
Boston, MassachusettsAges 18 years+ - NCT03647358RecruitingPhase 1
Iodine scan planning for metastatic thyroid cancer treatment
This early-stage study tests how well a special iodine scan (using iodine-124) can help plan treatment with radioactive iodine (iodine-131) for thyroid cancer that has spread. It may help doctors decide the right way to measure and target radioiodine-avid (radioiodine-absorbing) metastases.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,042 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.