Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 12,865 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06040125Recruiting
Exercise for frailty and muscle loss in men with prostate cancer
This trial tests a supervised exercise program to see if it can reduce frailty and muscle loss in men with metastatic prostate cancer who are on hormone therapy. It may help you become stronger and feel better during treatment.
Boston, MassachusettsAges 18 years+ - NCT06042569RecruitingPhase 2
Lower-dose chemo for older women with HER2-negative breast cancer
This trial tests whether a lower dose of two chemotherapy drugs (docetaxel and cyclophosphamide) works well for women 65 and older with early-stage HER2-negative breast cancer. The goal is to maintain effectiveness while reducing side effects in this group.
Duarte, CaliforniaAges 65 years+ - NCT04543799Recruiting
Sleep quality study in prostate and early breast cancer patients
This trial studies how sleep quality changes while people with prostate cancer or early breast cancer receive standard treatments. It may help doctors understand which treatment factors affect sleep and identify who might benefit from support for sleep problems.
BellinzonaAges 18 years+ - NCT06026943Recruiting
Alpha radiation therapy for locally advanced pancreatic cancer
This trial tests a new treatment that uses tiny alpha radiation sources placed directly into the tumor to destroy cancer cells. It is for people with pancreatic cancer that has not spread but cannot be removed surgically, and who have already tried at least one type of chemotherapy or cannot take more chemo.
VeronaAges 18–120 - NCT05979610RecruitingPhase 2
Reiki therapy for symptom relief during gynecologic radiation
This trial tests whether adding Reiki therapy (a gentle hands-on relaxation technique) can help reduce side effects like pain and anxiety during brachytherapy (internal radiation) for women with gynecologic cancers. Participants will be randomly assigned to receive Reiki plus usual care or usual care alone.
Salt Lake City, UtahAges 18 years+ - NCT05975437Enrolling by invitation
Personalized follow-up care after breast cancer treatment
This trial tests whether a personalized follow-up plan after breast cancer surgery (instead of a fixed schedule) can improve care and support after treatment. It may help people know what follow-up is best for them as they move into survivorship.
Apeldoorn, GelderlandAges 40 years+ - NCT05995821Recruiting
Blood and tissue collection for head and neck cancers
This study collects blood and tissue samples from people with cancers of the head, neck, or upper airway to learn how the immune system responds to these cancers. The goal is to find better ways to treat these diseases in the future.
Baltimore, MarylandAges 18 years+ - NCT05945732Recruiting
Testing T-DXd or chemo for HER2-low or HR-positive breast cancer
This study looks at treatment choices for adults with breast cancer that has spread and cannot be removed by surgery (unresectable metastatic disease). It focuses on people with HER2-low (and some HER2-ultralow) and/or hormone-receptor positive cancer, and compares how well treatments like T-DXd or standard chemotherapy work.
GrazAges 18 years+ - NCT05914974Recruiting
Tracking inflammation changes during immunotherapy in gynecologic cancer
This trial looks at how a blood inflammation marker (CRP) changes when people with metastatic gynecologic cancers receive immunotherapy, sometimes together with palliative chemotherapy. The goal is to see patterns that may help doctors better understand and manage treatment responses to immunotherapy.
TübingenAges 18 years+ - NCT04900935Recruiting
Survivorship and palliative care planning for metastatic lung cancer
This study tests a more patient-centered way to plan survivorship care and comfort (palliative) care for people with metastatic lung cancer. It may help you get support that matches your goals, especially alongside your current targeted treatment.
Boston, MassachusettsAges 18 years+ - NCT05903092RecruitingPhase 2
Monalizumab plus durvalumab for small cell lung cancer
This Phase 2 trial tests whether adding monalizumab to durvalumab (two immune-targeting medicines) can improve outcomes in people with small cell lung cancer. You may be able to join if you have certain stage of small cell lung cancer and have not had the specific prior treatments the study allows.
Indianapolis, IndianaAges 18 years+ - NCT05888532RecruitingPhase 1/Phase 2
Testing a copper-based scan and treatment in advanced cancers
This Phase 1/2 trial studies a copper-labeled medicine called 64Cu-GRIP B in people with advanced, metastatic cancers. It may help doctors see where cancer is and how well the drug works, especially alongside immune checkpoint therapy for some cancer types.
San Francisco, CaliforniaAges 18 years+ - NCT05849480RecruitingPhase 1/Phase 2
Study of CD40 treatment with CAPOX and Keytruda for bile duct cancer
This trial studies a new immune “switch” treatment called CDX-1140 combined with standard chemo (CAPOX) and Keytruda, for biliary tract cancer that can’t be cured with surgery or transplant. It’s designed for people whose cancer has progressed after first-line treatment, with the goal of improving cancer control and outcomes.
Bethesda, MarylandAges 18–120 - NCT05856981RecruitingPhase 1
Testing ADU-1805 for advanced solid tumors safety
This early study tests whether ADU-1805 is safe in people with advanced solid tumors and checks how the body processes the drug. Depending on your cancer type, it may also be looking specifically at certain cancers that have not yet received PD-(L)1 immunotherapy.
Detroit, MichiganAges 18 years+ - NCT05874492Recruiting
Spa therapy for radiation-related skin fibrosis after cancer
This trial tests whether a spa therapy program can improve “fibrosis,” or stiffened/scarred tissue and related skin problems, after radiotherapy for breast cancer or upper head/neck cancers. It aims to see if treatment can improve quality of life for people who still have moderate-to-worse symptoms months after radiation.
BordeauxAges 18 years+ - NCT05869682RecruitingPhase 2
Bright light therapy for fatigue and depression in prostate cancer
This Phase 2 study tests whether a “bright white light” intervention can reduce cancer-related fatigue and depression in people with advanced prostate cancer receiving hormone-based treatment. If it works, it could improve day-to-day well-being while you’re on standard cancer therapies.
Duarte, CaliforniaAges 60 years+ - NCT05837455RecruitingPhase 2
Biomarker-guided treatment for early breast cancer before surgery
This trial looks at whether using tumor test results (biomarkers) can help guide the best hormone treatment and chemotherapy before surgery. It focuses on people with stage II or III, ER-positive, HER2-negative breast cancer, with the goal of improving how well the tumor responds before it is removed.
St Louis, MissouriAges 18 years+ - NCT05812807RecruitingPhase 3
Pembrolizumab versus monitoring after triple-negative breast cancer response
This trial checks whether giving pembrolizumab (an immunotherapy) after surgery helps people with triple-negative breast cancer reduce the chance of the cancer coming back, compared with close monitoring only. It’s for patients who had no remaining invasive cancer after neoadjuvant chemotherapy plus pembrolizumab.
Birmingham, AlabamaAges 18 years+ - NCT05838716RecruitingPhase 3
Vitamin D During Hormone Therapy for Prostate Cancer
This trial studies whether taking vitamin D while you are on prostate hormone therapy (ADT) affects your health outcomes. It may help by keeping vitamin D levels in a safe range during treatment.
Newark, DelawareAges 50 years+ - NCT05837221Recruiting
Study of the mouth microbiome in oral cancer
This study looks at the types of bacteria in the mouth (the microbiome) in people with oral squamous cell cancer and compares them to people without this cancer. It may help researchers understand what’s different in oral cancer and what could be useful for diagnosis or treatment planning.
Aurora, ColoradoAges 18–100 - NCT05803382RecruitingPhase 1
Adding a new drug to capecitabine for metastatic colorectal cancer
This Phase 1 study tests a new anti-cancer drug (ZEN003694) added to the usual chemotherapy capecitabine. It is for adults with colorectal cancer (and possibly other cancers) that has spread or cannot be removed and has continued despite prior standard treatment.
Irvine, CaliforniaAges 18 years+ - NCT05806515RecruitingPhase 2
Carboplatin before surgery for high-risk BRCA prostate cancer
This trial tests giving the chemotherapy drug carboplatin before surgery to treat people with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene change. The goal is to shrink or control the cancer before an operation and improve outcomes.
Anchorage, AlaskaAges 18 years+ - NCT05642819Recruiting
MRI before and after surgery for abdominal cancers
This study uses extra detailed MRI scans before and/or around planned abdominal surgery to help researchers understand changes in the body. It includes people having surgery for certain cancers and some people having surgery for non-cancer (benign) conditions.
EdinburghAges 18 years+ - NCT05786664Recruiting
Breast cancer survivor study collecting your health samples
This study invites women who finished treatment for non-metastatic invasive breast cancer to share health information and biological samples for future research. It may help scientists understand survivorship and improve care after treatment.
Los Angeles, CaliforniaAges 18 years+
Hear when a new Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 12,865 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.