Clinical trials
Cardiac Surgery in Adult Patient clinical trials
Below are recruiting cardiac surgery in adult patient clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06493227Recruiting
Extended use of bleeding control drugs after heart surgery
This trial is for hospitals, not patients. Hospitals that do many open heart surgeries and whose doctors agree to use certain bleeding control drugs (fibrinolysis inhibitors) as per the study protocol can participate.
Saint PetersburgAges 18 years+ - NCT07328425RecruitingPhase 2
A study of lurbinectedin and irinotecan for advanced DSRCT
This trial tests a combination of two chemotherapy drugs (lurbinectedin and irinotecan) for people with desmoplastic small round cell tumor (DSRCT) that has spread or cannot be removed by surgery. It is for patients whose cancer has gotten worse after at least one prior treatment.
Candiolo, TorinoAges 15 years+ - NCT07303855Recruiting
Better fluid management after major abdominal surgery
This study compares two ways of giving fluids to people after major abdominal surgery in the ICU. It will see if using a measure of how much blood the heart pumps (cardiac index) is better than the usual method based on vein pressure.
Jakarta Pusat, DKI JakartaAges 18–65 - NCT06014489RecruitingPhase 2
Venetoclax with azacitidine for untreated AML
This trial tests a combination of venetoclax and azacitidine for people with newly diagnosed acute myeloid leukemia (AML) who cannot have or choose not to have intensive chemotherapy. The goal is to see if adding a drug called cobicistat helps the treatment work better.
AmersfoortAges 18 years+ - NCT07048002Recruiting
Silent brain infarct and cognitive decline after heart surgery
This trial tests a bundle of interventions to prevent silent brain infarctions (small 'silent' strokes) and thinking problems after heart or blood vessel surgery with a heart-lung machine. If you are 60 or older and having such surgery, this study may help protect your brain health.
Beijing, Beijing MunicipalityAges 60 years+ - NCT04443088RecruitingPhase 1
Study drug INV-1120 with or without pembrolizumab for advanced cancers
This Phase 1 trial studies INV-1120 alone and with pembrolizumab (an immune therapy) in adults with advanced solid tumors that have stopped responding to standard treatment or have no standard option. The goal is to see how the treatments work, what dose is safest, and what side effects may occur.
Lafayette, IndianaAges 18 years+ - NCT05664308Recruiting
Watch-based heart rhythm monitoring after heart surgery
This study tests whether a connected watch can help monitor an irregular heart rhythm (atrial fibrillation) after heart surgery. It looks at people who develop new atrial fibrillation after surgery and compares how well monitoring works over the next 12 months.
Nantes, Loire AtlantiqueAges 18 years+ - NCT06246071RecruitingPhase 1
TYK-00540 for adults with solid tumors
This trial tests a new drug, TYK-00540, for people with solid tumors that have not responded to or cannot tolerate standard treatments. It also looks at specific types of breast and ovarian cancer.
HefeiAges 18 years+ - NCT04912596Recruiting
Tested albuterol inhaler compared to a standard inhaler for mild asthma
This study checks whether a new albuterol inhaler works the same way as a reference inhaler in adults with stable, mild asthma. It may help you (and others) by confirming that the inhaler delivers the right effect and is safe to use.
AhmedabadAges 20–65 - NCT06464263Recruiting
Dexmedetomidine vs. midazolam-fentanyl for sedation
This trial compares two sedation and pain relief medicine combinations (dexmedetomidine vs. midazolam-fentanyl) to see which works better for people having planned heart valve surgery.
CairoAges 21–50 - NCT06230198Recruiting
Effect of a blood-saving technique on transfusions after heart surgery
This trial tests whether a technique called retrograde autologous priming (using the patient's own blood to prepare the heart-lung machine) can reduce the need for blood transfusions during heart surgery. It is looking at hospitals and surgical teams, not individual patients, so it's not a typical trial you can join directly.
Winnipeg, ManitobaAges 10–110 - NCT04412616RecruitingPhase 1
Study drug for advanced EGFR-positive solid tumors
This early-phase trial tests a new drug (ZZ06) in adults with advanced solid cancers that have an EGFR “positive” tumor test result. It’s for people whose cancer has grown despite standard treatment or who don’t have a standard option.
Los Angeles, CaliforniaAges 18 years+ - NCT07370103Recruiting
Predicting low blood pressure in liver disease patients after anesthesia
This study uses an ultrasound to measure blood flow in the neck's main artery to see if it can predict a dangerous drop in blood pressure after you are put to sleep for surgery. It is for adult patients with chronic liver disease who are having planned surgery.
CairoAges 18 years+ - NCT07179029Recruiting
Can anesthesia affect the heart during non-cardiac surgery?
This study looks at whether anesthesia can cause heart damage during non-cardiac surgeries. If you have certain health risks, participating may help doctors learn how to better protect your heart.
TübingenAges 40–80 - NCT07057622RecruitingPhase 3
Comparing a new radiation therapy and long-acting medication for neuroendocrine tumors
This phase 3 trial tests a radioactive drug (177Lu-DOTATATE) against a long-acting medication (Octreotide LAR) for people with advanced neuroendocrine tumors (NETs) that have grown despite standard treatment. The study aims to see which treatment works better and is safer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05824260Recruiting
Study of risk factors for complications after major surgery
This study looks at patients who've had major abdominal, bone, or blood-vessel surgery to understand what factors make some people more likely to have complications afterward. It analyzes information already collected from hospitals to help doctors better predict and prevent problems.
AmiensAges 18 years+ - NCT04365179RecruitingPhase 1
NEROFE for advanced MDS or AML after other treatments
This early-phase trial tests NEROFE, a hormone-peptide medicine, in adults with advanced myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that has come back or did not respond. It aims to see if NEROFE is safe and can help patients whose disease is unlikely to benefit from standard remaining options.
Miami, FloridaAges 18 years+ - NCT05944146Recruiting
Tests two methods for measuring heart blood flow during surgery
This trial compares a neck ultrasound test (carotid Doppler) with a heart monitoring method (thermodilution) to see if they give consistent blood-flow readings. It may help clinicians measure circulation more reliably in people having heart surgery.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07646613RecruitingPhase 2
Testing an inhaled migraine medicine for quick relief
This study tests a new inhaled powder form of a migraine medication called dihydroergotamine (DHE) to see if it safely and effectively stops migraine attacks. If you have frequent migraines, this trial might offer you a new treatment option to try.
Walnut Creek, CaliforniaAges 18–65 - NCT04574440Recruiting
Near-infrared brain scan during planned heart surgery
This trial tests a non-painful near-infrared brain scan (placed on the forehead) during planned adult heart surgery. It may help doctors better understand how the brain responds during surgery and improve care.
London, OntarioAges 18 years+ - NCT04833751Recruiting
Study of heart and brain monitoring around heart surgery anesthesia
This study collects heart and brain signal information before and during anesthesia for people having cardiovascular surgery or procedures. The goal is to better understand risk and outcomes, and to improve how anesthesia is assessed.
SeoulAges 19 years+ - NCT04925609RecruitingPhase 1/Phase 2
Brigatinib for young people with ALK-positive cancer
This trial tests brigatinib, a targeted pill medicine, in children and young adults with ALK-positive cancers (including ALCL and IMT, plus some other solid tumors). It’s designed to see how well it works and what side effects it causes in people whose tumors have a specific ALK change.
ParisAges 1–25 - NCT05573633Recruiting
Smartwatch test to detect irregular heartbeats after heart surgery
This study checks whether a smartwatch can spot an irregular heartbeat called atrial fibrillation soon after on-pump heart surgery. If the smartwatch works well, it could help clinicians find the problem earlier after surgery.
AmiensAges 18 years+ - NCT05577754RecruitingPhase 2
Trial tests alpelisib for MCAP with PIK3CA mutations
This Phase 2 study tests alpelisib in children and adults with MCAP, a condition caused by a specific PIK3CA gene mutation. The goal is to see if the treatment is effective and safe, while carefully monitoring blood sugar and organ function.
AmiensAges 2–40
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Common questions
- Are there clinical trials for cardiac surgery in adult patient?
- Yes. Clin2 currently lists 122 recruiting cardiac surgery in adult patient studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery in adult patient trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery in adult patient trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.