Clinical trials
Cardiac Surgery in Adult Patient clinical trials
Below are recruiting cardiac surgery in adult patient clinical trials, each written for real people, not researchers. We’re tracking 126 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06205875Recruiting
High vs. low dose pain block after minimally invasive heart valve surgery
This trial compares two doses of a numbing medicine injected into the chest wall to control pain after heart valve surgery. If you qualify, you will receive either a higher or lower dose of the pain block to see which provides better pain relief and recovery.
Hasselt, LimburgAges 18 years+ - NCT06493227Recruiting
Extended use of bleeding control drugs after heart surgery
This trial is for hospitals, not patients. Hospitals that do many open heart surgeries and whose doctors agree to use certain bleeding control drugs (fibrinolysis inhibitors) as per the study protocol can participate.
Saint PetersburgAges 18 years+ - NCT07328425RecruitingPhase 2
A study of lurbinectedin and irinotecan for advanced DSRCT
This trial tests a combination of two chemotherapy drugs (lurbinectedin and irinotecan) for people with desmoplastic small round cell tumor (DSRCT) that has spread or cannot be removed by surgery. It is for patients whose cancer has gotten worse after at least one prior treatment.
Candiolo, TorinoAges 15 years+ - NCT07303855Recruiting
Better fluid management after major abdominal surgery
This study compares two ways of giving fluids to people after major abdominal surgery in the ICU. It will see if using a measure of how much blood the heart pumps (cardiac index) is better than the usual method based on vein pressure.
Jakarta Pusat, DKI JakartaAges 18–65 - NCT07048002Recruiting
Silent brain infarct and cognitive decline after heart surgery
This trial tests a bundle of interventions to prevent silent brain infarctions (small 'silent' strokes) and thinking problems after heart or blood vessel surgery with a heart-lung machine. If you are 60 or older and having such surgery, this study may help protect your brain health.
Beijing, Beijing MunicipalityAges 60 years+ - NCT06014489RecruitingPhase 2
New combination for AML in people who can't have intensive chemo
This trial tests a new combination of two drugs—venetoclax and azacitidine—for people with acute myeloid leukemia (AML) who can't have standard intensive chemo. The goal is to see if adding a boosting medicine (cobicistat) makes the treatment work better and is safe for you.
's-HertogenboschAges 18 years+ - NCT04443088RecruitingPhase 1
Study drug INV-1120 with or without pembrolizumab for advanced cancers
This Phase 1 trial studies INV-1120 alone and with pembrolizumab (an immune therapy) in adults with advanced solid tumors that have stopped responding to standard treatment or have no standard option. The goal is to see how the treatments work, what dose is safest, and what side effects may occur.
Lafayette, IndianaAges 18 years+ - NCT05664308Recruiting
Watch-based heart rhythm monitoring after heart surgery
This study tests whether a connected watch can help monitor an irregular heart rhythm (atrial fibrillation) after heart surgery. It looks at people who develop new atrial fibrillation after surgery and compares how well monitoring works over the next 12 months.
Nantes, Loire AtlantiqueAges 18 years+ - NCT07795112Recruiting
Acupuncture for reducing inflammation after heart surgery
This study tests whether acupuncture at a specific point (ST36) can reduce inflammation after heart surgery. If you are having heart surgery with a bypass machine, you may be able to join and receive this additional treatment to help your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT07094737Recruiting
Cardiac rehabilitation for heart attack and heart failure recovery
This study tracks patients with heart disease or heart failure who are in cardiac rehabilitation. The goal is to understand how well these programs work in real life and improve care for future patients.
MilanAges 18 years+ - NCT05944146Recruiting
Tests two methods for measuring heart blood flow during surgery
This trial compares a neck ultrasound test (carotid Doppler) with a heart monitoring method (thermodilution) to see if they give consistent blood-flow readings. It may help clinicians measure circulation more reliably in people having heart surgery.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07871188Recruiting
Blood pressure swings and recovery after heart bypass surgery
This study looks at how changes in blood pressure during heart bypass surgery relate to how quickly the body clears lactic acid afterwards, which is a sign of recovery. It may help doctors understand recovery patterns after surgery.
GaziantepAges 18–80 - NCT06246071RecruitingPhase 1
TYK-00540 for adults with solid tumors
This trial tests a new drug, TYK-00540, for people with solid tumors that have not responded to or cannot tolerate standard treatments. It also looks at specific types of breast and ovarian cancer.
HefeiAges 18 years+ - NCT04833751Recruiting
Study of heart and brain monitoring around heart surgery anesthesia
This study collects heart and brain signal information before and during anesthesia for people having cardiovascular surgery or procedures. The goal is to better understand risk and outcomes, and to improve how anesthesia is assessed.
SeoulAges 19 years+ - NCT07646613RecruitingPhase 2
Testing an inhaled migraine medicine for quick relief
This study tests a new inhaled powder form of a migraine medication called dihydroergotamine (DHE) to see if it safely and effectively stops migraine attacks. If you have frequent migraines, this trial might offer you a new treatment option to try.
Phoenix, ArizonaAges 18–65 - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT06728371RecruitingPhase 3
IV methadone for pain after heart surgery
This trial tests if methadone given through a vein can control pain better after heart surgery done through a breastbone incision. It may be an option for adults having planned heart surgery who are expected to wake up and breathe on their own within 12 hours.
Hong KongAges 18 years+ - NCT06770764RecruitingPhase 1
Testing ODC-IL2 for advanced solid tumors
This trial tests a new drug called ODC-IL2 for people with advanced solid tumors that have stopped responding to standard treatments. The drug is designed to help your immune system fight cancer. The study starts with small doses to find the best dose, then expands to see how well it works.
Scottsdale, ArizonaAges 18 years+ - NCT04912596Recruiting
Tested albuterol inhaler compared to a standard inhaler for mild asthma
This study checks whether a new albuterol inhaler works the same way as a reference inhaler in adults with stable, mild asthma. It may help you (and others) by confirming that the inhaler delivers the right effect and is safe to use.
AhmedabadAges 20–65 - NCT07370103Recruiting
Predicting low blood pressure in liver disease patients after anesthesia
This study uses an ultrasound to measure blood flow in the neck's main artery to see if it can predict a dangerous drop in blood pressure after you are put to sleep for surgery. It is for adult patients with chronic liver disease who are having planned surgery.
CairoAges 18 years+ - NCT07361289Recruiting
Mavacamten for obstructive hypertrophic cardiomyopathy in China
This study looks at how well mavacamten works in real life for adults with obstructive hypertrophic cardiomyopathy, a condition where the heart muscle is thickened and blocks blood flow. It may help improve symptoms like shortness of breath or chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06230198Recruiting
Effect of a blood-saving technique on transfusions after heart surgery
This trial tests whether a technique called retrograde autologous priming (using the patient's own blood to prepare the heart-lung machine) can reduce the need for blood transfusions during heart surgery. It is looking at hospitals and surgical teams, not individual patients, so it's not a typical trial you can join directly.
Winnipeg, ManitobaAges 10–110 - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT07179029Recruiting
Can anesthesia affect the heart during non-cardiac surgery?
This study looks at whether anesthesia can cause heart damage during non-cardiac surgeries. If you have certain health risks, participating may help doctors learn how to better protect your heart.
TübingenAges 40–80
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Common questions
- Are there clinical trials for cardiac surgery in adult patient?
- Yes. Clin2 currently lists 126 recruiting cardiac surgery in adult patient studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery in adult patient trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery in adult patient trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.