Clinical trials
Cardiac Surgery in Adult Patient clinical trials
Below are recruiting cardiac surgery in adult patient clinical trials, each written for real people, not researchers. We’re tracking 125 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06706258RecruitingPhase 2
Preventing kidney injury after heart surgery with a stomach acid drug
This trial tests whether giving a common stomach acid medication (a proton pump inhibitor) before, during, and after heart surgery can help prevent acute kidney injury. If you are at moderate to high risk for kidney problems after surgery, this study may be a good fit.
Houston, TexasAges 18–90 - NCT07057622RecruitingPhase 3
Comparing a new radiation therapy and long-acting medication for neuroendocrine tumors
This phase 3 trial tests a radioactive drug (177Lu-DOTATATE) against a long-acting medication (Octreotide LAR) for people with advanced neuroendocrine tumors (NETs) that have grown despite standard treatment. The study aims to see which treatment works better and is safer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07064954RecruitingPhase 2/Phase 3
Using your own platelets for complex heart surgery recovery
This study tests whether using your own donated platelets during heart surgery can help you recover better. Platelets are cells that help your blood clot, and donating them before surgery may reduce the need for donor blood.
Toronto, OntarioAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT06988475RecruitingPhase 2/Phase 3
Capmatinib for cancers with MET gene changes
This study tests an oral drug called capmatinib for people whose cancers have specific changes in the MET gene (except for one type of lung cancer). It aims to see if the drug can shrink tumors or slow their growth.
BelfastAges 18 years+ - NCT04412616RecruitingPhase 1
Study drug for advanced EGFR-positive solid tumors
This early-phase trial tests a new drug (ZZ06) in adults with advanced solid cancers that have an EGFR “positive” tumor test result. It’s for people whose cancer has grown despite standard treatment or who don’t have a standard option.
Los Angeles, CaliforniaAges 18 years+ - NCT06932003RecruitingPhase 1/Phase 2
Testing a new tablet for hidradenitis suppurativa
This trial is testing an experimental tablet called LT-002-158 in adults with moderate to severe hidradenitis suppurativa (HS) that hasn't improved enough with standard treatments. The goal is to see if it's safe and helps reduce painful lumps and abscesses.
Beijing, Beijing MunicipalityAges 18–75 - NCT06906562RecruitingPhase 2
Pemigatinib for advanced pancreatic cancer with FGFR changes
This trial tests a targeted pill, pemigatinib, for people with advanced pancreatic cancer that has a specific FGFR gene change. The study is done entirely through telemedicine, so you can participate from home if eligible.
Birmingham, AlabamaAges 18 years+ - NCT06648889RecruitingPhase 2
Isatuximab for relapsed or hard-to-treat T-cell leukemia
This trial tests a drug called isatuximab for people with a type of leukemia (T-cell acute lymphoblastic leukemia) that has come back after treatment or that did not go away. Isatuximab targets a protein on the leukemia cells, which might help the immune system fight the disease.
AugsburgAges 18 years+ - NCT06609005RecruitingPhase 1/Phase 2
Study of INV-9956 for advanced prostate cancer
This trial tests a new drug called INV-9956 in men with advanced prostate cancer that no longer responds to hormone therapy and has spread to other parts of the body. It aims to see if the drug is safe and effective.
Scottsdale, ArizonaAges 18 years+ - NCT06561074RecruitingPhase 2
Study of calaspargase, decitabine, and venetoclax for young T-cell cancer
This trial tests a combination of three drugs (calaspargase, decitabine, and venetoclax) for children, teens, and young adults with T-cell leukemia or lymphoma that has come back or not responded to treatment. The goal is to see if this combination can help destroy cancer cells.
Houston, TexasAges 1 month–21 years - NCT06037018RecruitingPhase 1
Study of CC312 for B-cell blood cancers
This trial tests a new drug called CC312 for people with B-cell blood cancers that have come back or stopped responding to treatment. CC312 is designed to target CD19 on cancer cells, and the study checks if it is safe and how the body handles it.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06322810Recruiting
Pain relief methods for open heart surgery: ESP vs PIFB
This study compares two ways to manage pain after open-heart surgery. It looks at using an injection near the spine (ESP block) versus a needle placed through the chest wall (PIFB) to help reduce pain and the need for strong pain medicines.
Taichung, TaiwanAges 18 years+ - NCT05824260Recruiting
Study of risk factors for complications after major surgery
This study looks at patients who've had major abdominal, bone, or blood-vessel surgery to understand what factors make some people more likely to have complications afterward. It analyzes information already collected from hospitals to help doctors better predict and prevent problems.
AmiensAges 18 years+ - NCT04925609RecruitingPhase 1/Phase 2
Brigatinib for young people with ALK-positive cancer
This trial tests brigatinib, a targeted pill medicine, in children and young adults with ALK-positive cancers (including ALCL and IMT, plus some other solid tumors). It’s designed to see how well it works and what side effects it causes in people whose tumors have a specific ALK change.
ParisAges 1–25 - NCT05577754RecruitingPhase 2
Trial tests alpelisib for MCAP with PIK3CA mutations
This Phase 2 study tests alpelisib in children and adults with MCAP, a condition caused by a specific PIK3CA gene mutation. The goal is to see if the treatment is effective and safe, while carefully monitoring blood sugar and organ function.
AmiensAges 2–40 - NCT05573633Recruiting
Smartwatch test to detect irregular heartbeats after heart surgery
This study checks whether a smartwatch can spot an irregular heartbeat called atrial fibrillation soon after on-pump heart surgery. If the smartwatch works well, it could help clinicians find the problem earlier after surgery.
AmiensAges 18 years+ - NCT07162506RecruitingPhase 2
Comparing further treatment options for esophageal cancer after chemo-immunotherapy
This trial compares two approaches for people with esophageal cancer that has shrunk or disappeared after initial chemotherapy combined with immunotherapy. It looks at whether adding targeted radiation (DCRT) or surgery is better. The goal is to find the most effective next step for eligible patients.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07144462RecruitingEarly Phase 1
Testing a new drug for people with certain autoimmune diseases that have come back or not responded to treatment
This trial is testing a new injection, NEUK203-215, in adults aged 18-65 with certain autoimmune diseases (like lupus, scleroderma, inflammatory myopathy, or a skin blistering condition) that have relapsed or not responded to standard therapy. The goal is to see if it is safe, tolerable, and may help control the disease.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06519682Recruiting
Immunotherapy for young people with a specific brain tumor
This trial is testing a new immunotherapy (nivolumab) for children, teens, and young adults with a specific type of aggressive brain tumor (glioblastoma that has a DNA repair problem). It aims to see if giving this treatment early, right after surgery, can help the immune system fight the tumor.
Toronto, OntarioAges 1–25 - NCT07505758Recruiting
Recovery after surgery in adults 80 and older
This study looks at how well adults aged 80 or older recover after planned surgery that requires an overnight hospital stay. The goal is to understand recovery using a simple questionnaire.
Barcelona, BarcelonaAges 80 years+ - NCT07590635Recruiting
Heart Recovery Program Using Online Health Tools
This study tests a new heart rehabilitation program that combines online tools with personalized support for people who've had heart procedures. It aims to help you recover safely and manage your heart health from home.
BergenAges 18 years+ - NCT07749768RecruitingPhase 1
Oral drug for ulcerative colitis safety study
This study tests an investigational oral drug for ulcerative colitis. It is an early-stage trial to check safety and how the drug is processed by the body in both healthy volunteers and patients with active ulcerative colitis.
Miami, FloridaAges 18–55 - NCT06089902Recruiting
European registry for anomalous aortic origin of coronary arteries
This is a European registry for people with an anomalous origin of a coronary artery from the aorta (AAOCA). It will track how the condition is treated—whether with surgery or monitoring—to learn what works best.
Padova, PDAges Any age
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Common questions
- Are there clinical trials for cardiac surgery in adult patient?
- Yes. Clin2 currently lists 125 recruiting cardiac surgery in adult patient studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery in adult patient trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery in adult patient trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.