Clinical trials
Cardiac Surgery Requiring Cardiopulmonary Bypass clinical trials
Below are recruiting cardiac surgery requiring cardiopulmonary bypass clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03204357Recruiting
Using your own blood after heart-lung machine surgery
This trial studies giving a “fresh” blood transfusion from your own blood after heart surgery that uses a heart-lung machine. It may help patients avoid needing donated blood, but it only works for people who meet specific safety and timing requirements.
Aurora, ColoradoAges 18–90 - NCT07483047Recruiting
Predicting memory changes after heart surgery in older adults
This study looks at older adults having heart surgery to find out who might have trouble thinking or remembering afterward. Researchers hope to build a tool to predict this risk so doctors can help sooner.
ShanghaiAges 65 years+ - NCT06230198Recruiting
Effect of a blood-saving technique on transfusions after heart surgery
This trial tests whether a technique called retrograde autologous priming (using the patient's own blood to prepare the heart-lung machine) can reduce the need for blood transfusions during heart surgery. It is looking at hospitals and surgical teams, not individual patients, so it's not a typical trial you can join directly.
Winnipeg, ManitobaAges 10–110 - NCT06487585RecruitingPhase 4
Angiotensin II as first pressor after heart surgery
This trial tests if starting Angiotensin II early, instead of other blood pressure medications, can help heart surgery patients maintain safe blood pressure. It may be an option if you have low blood pressure after surgery despite receiving fluids.
Towson, MarylandAges 18 years+ - NCT07477977Recruiting
Finding the right dose of protamine to reverse heparin after heart bypass
This study is testing different doses of a medication called protamine, which is given after heart surgery to reverse the effects of heparin (a blood thinner). The goal is to find the safest and most effective dose for patients who have had a heart-lung bypass machine during surgery.
SohagAges 18 years+ - NCT06355063Recruiting
CellFX device for atrial fibrillation during open-heart surgery
This trial tests a new device called CellFX that uses nanosecond pulsed field ablation to treat atrial fibrillation during open-heart surgery. It may help you if you already need heart surgery and also have AFib.
ViennaAges 18–85 - NCT05927233RecruitingPhase 4
Methylprednisolone in children after open-heart surgery
This trial tests whether giving methylprednisolone (a steroid medicine) can lower the body’s inflammatory response in children during the first day after congenital open-heart surgery. It may help reduce harmful inflammation and improve recovery for some children undergoing their first surgery.
Karachi, SindhAges 1 month–18 years - NCT06013189Recruiting
Adjusting gas flow during heart-lung machine rewarming
This study tests how adjusting the amount of sweep gas (a gas mixture) during the rewarming phase of heart-lung machine use might affect patients. It's for people having planned heart surgery with a standard heart-lung machine, not minimally invasive or robotic surgery.
Istanbul, AltunizadeAges 18 years+ - NCT06959121Recruiting
Treating AFib during open-heart surgery with a new device
This trial tests a new device used during open-heart surgery to treat atrial fibrillation (AFib) by delivering tiny, fast electrical pulses to the heart tissue. It is for people who are already having heart surgery and want to also treat their AFib at the same time.
St. Helena, CaliforniaAges 18–85 - NCT06772025Recruiting
Understanding kidney injury after heart surgery with heart-lung machine
This study looks at why some people develop kidney damage after heart surgery that uses a heart-lung machine. It aims to help doctors better predict and prevent this complication.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT06756789Recruiting
Comparing standard vs. tailored limb lengths in gastric bypass
This study compares two different ways of measuring the length of the small intestine during a type of weight loss surgery called gastric bypass. If you are eligible, you may help determine which approach leads to better weight loss results.
Coimbatore, Tamil NaduAges 18–65 - NCT06952907Recruiting
Arm vs. leg artery pressure monitoring in heart surgery
This study compares measuring blood pressure through an arm artery (radial) versus a leg artery (femoral) during heart surgery that uses a heart-lung machine. The goal is to see which method works better and is safer for patients.
BesançonAges 18 years+ - NCT07390903Recruiting
Heart function test for difficult bypass weaning
This trial studies whether a heart ultrasound test called GLS can help predict complications when patients are taken off the heart-lung machine after heart surgery. It aims to improve management for better outcomes.
RomeAges 18 years+ - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT06349577Recruiting
Bypass machine settings to protect kidneys during heart surgery
This study tests whether a special way of running the heart-lung bypass machine during planned heart surgery can help protect your kidneys and reduce the risk of kidney injury after the operation.
Aurora, ColoradoAges 18–85 - NCT05595954Recruiting
Personalized anesthesia plan to protect the brain during heart surgery
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
BaselAges 65 years+ - NCT07278661RecruitingPhase 2
Pre-surgery romiplostim for patients with low platelets having heart surgery
This trial tests if giving romiplostim before heart surgery can safely increase low platelet counts. It may help patients with low platelets avoid bleeding complications during and after surgery.
AngersAges 18 years+ - NCT05344573Recruiting
Testing better blood-flow rhythms during heart bypass surgery
This trial studies ways to control the “pulsatility” (how the blood pressure pulses during circulation) while you are on a heart-lung bypass machine. It may help improve safety and heart function during planned heart surgery.
Aurora, ColoradoAges 50–70 - NCT05999721Recruiting
Nerve block for better breathing after heart surgery
This trial is testing a nerve block (a numbing injection) placed near the breastbone to see if it helps your lungs work better after heart surgery. If you are having planned heart surgery through a breastbone cut, you may be able to join.
Petah TikvaAges 18 years+ - NCT07401836Recruiting
Sleep bundle for heart surgery patients
This trial tests a special sleep program (bundle) to help patients sleep better after heart surgery. Researchers want to see if it improves recovery and well-being.
Saint John, New BrunswickAges 19 years+ - NCT07432477Recruiting
Lung opening techniques after heart surgery
This trial compares two methods of opening the lungs (recruitment maneuvers) after heart-lung bypass to see which works better. The study aims to help patients recover their lung function more quickly after cardiac surgery.
Samsun, AtakumAges 18–80 - NCT07625553RecruitingPhase 2
Relaxin Agonist to Protect Kidneys During Heart Surgery
This study tests whether a drug called R2R01 can help protect your kidneys during major heart surgery. Heart surgery can sometimes damage the kidneys, and this trial is looking to see if this new medication reduces that risk.
MilanAges 18 years+
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Common questions
- Are there clinical trials for cardiac surgery requiring cardiopulmonary bypass?
- Yes. Clin2 currently lists 46 recruiting cardiac surgery requiring cardiopulmonary bypass studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery requiring cardiopulmonary bypass trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery requiring cardiopulmonary bypass trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.