Clinical trials
Cardiac Surgery With Cardiopulmonary Bypass clinical trials
Below are recruiting cardiac surgery with cardiopulmonary bypass clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03302195Recruiting
Heparin and bypass blood management for obese heart surgery
This trial studies the best way to manage blood thinning (anticoagulation) during heart surgery that uses a heart-lung machine in people with obesity. It may help reduce blood-clotting and bleeding complications by comparing different care strategies.
Québec, QuebecAges 18 years+ - NCT07857811Recruiting
Blood pressure monitoring in young children during heart surgery
This study looks at how blood pressure readings from the arm compare to readings from the aorta during heart surgery with a heart-lung machine in children up to 3 years old. It aims to improve blood pressure monitoring during and after surgery.
Santiago, Santiago MetropolitanAges birth–3 years - NCT06109155RecruitingPhase 4
Comparing medications to reduce bleeding in heart surgery
This trial tests two medicines—ACT (a blood thinner) and tranexamic acid (a medicine to reduce bleeding)—to see which is better at controlling bleeding during heart surgery. It is for adults having planned heart surgery with a heart-lung machine.
TaichungAges 18 years+ - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT07798011Recruiting
Faster breathing tube removal after pediatric heart surgery
This study compares two ways of helping children wake up and breathe on their own after minimally invasive heart surgery. One group gets a drug to quickly reverse the muscle relaxant, while the other group waits for it to wear off naturally. The goal is to see which method allows a safer, earlier breathing tube removal.
HanoiAges 2–18 - NCT07795112Recruiting
Acupuncture for reducing inflammation after heart surgery
This study tests whether acupuncture at a specific point (ST36) can reduce inflammation after heart surgery. If you are having heart surgery with a bypass machine, you may be able to join and receive this additional treatment to help your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT07744009Recruiting
Awake breathing support for heart valve surgery
This trial tests a new anesthesia method that lets you breathe on your own during heart valve surgery, instead of using a breathing tube. It aims to see if this approach is safer and helps you recover faster than standard anesthesia.
Guangzhou, GuangdongAges 18 years+ - NCT07683299Recruiting
New heart monitoring during bypass surgery
This study tests a new way to monitor your heart and blood flow during heart surgery that uses a heart-lung machine. The goal is to see if this integrated approach helps doctors make better decisions during the operation.
Medellín, AntioquiaAges 18 years+ - NCT06673953Recruiting
Breathing training for heart surgery recovery with neck posture problems
This trial tests whether a breathing exercise device can improve heart and lung function in men who had heart bypass surgery at least 3 months ago and also have neck pain from poor posture. It may help you breathe better and feel stronger after surgery.
Giza, Giza GovernorateAges 45–55 - NCT07632131Recruiting
Storytelling therapy to prevent PTSD after heart surgery
This study tests whether a special therapy called narrative exposure—where you talk through your surgery experience with a trained counselor—can help prevent PTSD (post-traumatic stress) in people recovering from heart surgery in the ICU. The goal is to help you process what happened so you feel less distressed afterward.
Fuzhou, FujianAges 18 years+ - NCT07549243Recruiting
Ear Nerve Stimulation to Protect Kidneys During Heart Surgery
This trial tests whether gentle electrical stimulation applied to your ear can help protect your kidneys during heart surgery that uses a heart-lung machine. Kidney damage after this type of surgery is common, and researchers want to see if this non-invasive stimulation can prevent it.
Hangzhou, ZhejiangAges 18 years+ - NCT07518524Recruiting
Fast Recovery After Heart Valve Surgery
This trial compares two recovery approaches after heart valve surgery: one that wakes you up very quickly in the operating room, and one that's slightly less aggressive. Both use techniques that avoid large chest incisions. The goal is to see which approach gets you breathing on your own sooner and helps you recover faster.
Legnano, ItalyAges 18 years+ - NCT06632613RecruitingPhase 2
Trial of ENN0403 to prevent kidney injury after heart surgery
This study tests a new drug (ENN0403) given during heart surgery to see if it prevents acute kidney injury—a sudden drop in kidney function. The trial is for people who are already at higher risk due to their specific heart surgery and other health factors.
ShanghaiAges 18–85 - NCT06786416Recruiting
Monitoring to prevent kidney injury after heart surgery
This trial is testing a new monitoring system that tracks blood flow and other vital signs during heart surgery to help prevent kidney damage afterward.
San Donato Milanese, MilanoAges 18 years+ - NCT07354841Recruiting
Testing safety of heart-lung machine tubes
This study tests two types of tubes used during heart surgery to connect you to a heart-lung machine. It aims to see if they work safely and effectively.
Bari, BAAges 18 years+ - NCT07286227Recruiting
Checking heart function before removing support tubes in heart surgery
This study compares two methods—visual checks and a special ultrasound of the heart—to see which better predicts how well the heart will pump after bypass machine support is removed during elective heart surgery.
ErzurumAges 18–75 - NCT05996120Recruiting
Finding the best temperature during heart-lung machine surgery
This study looks at the best body temperature to use during heart surgery when a heart-lung machine is needed. You may be able to join if you are having bypass surgery or valve repair, your risk score is moderate or higher, and your surgery is not an emergency.
Leicester, LeicestershireAges 18 years+ - NCT06917859RecruitingPhase 1
Steroid to protect kidneys during heart surgery
This trial is testing whether a single dose of the steroid methylprednisolone, given before heart surgery, can protect your kidneys from damage during the operation. If you qualify, you'll receive the drug or a placebo, and your kidney function will be monitored closely.
Cairo, AbbasiaAges 18–65 - NCT07193719RecruitingPhase 1/Phase 2
Personalized breathing support for kids after heart surgery
This study tests a personalized breathing technique to improve lung function and heart performance in children who have had heart surgery or are on ECMO. The goal is to find the best way to open up the lungs safely.
BerlinAges birth–18 years - NCT06930443Recruiting
Oxygen use and organ injury after heart-lung bypass surgery
This trial looks at how oxygen is used during heart surgery that uses a heart-lung machine, and whether low oxygen levels can lead to organ damage. It may help doctors better understand how to protect patients during surgery.
Uppsala, SwedenAges 18 years+ - NCT07094087RecruitingPhase 3
Blood clotting medicine for heart surgery bleeding
This trial tests a medicine called 4F-PCC to stop bleeding during complex heart surgery that uses a heart-lung machine. It could help people who have bleeding problems after the surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07077772Recruiting
Guiding fluid removal after heart surgery
This trial tests a method to guide how much fluid is removed after heart surgery using a urine salt test, to see if it helps patients recover better. If you are having planned heart surgery with a heart-lung machine, you may be able to join.
AmiensAges 18 years+ - NCT07064954RecruitingPhase 2/Phase 3
Using your own platelets for complex heart surgery recovery
This study tests whether using your own donated platelets during heart surgery can help you recover better. Platelets are cells that help your blood clot, and donating them before surgery may reduce the need for donor blood.
Toronto, OntarioAges 18 years+ - NCT05817929Recruiting
Angiopoietin levels and outcomes after heart bypass surgery
This study looks at how a blood protein called angiopoietin relates to recovery and complications after heart surgery that uses a heart-lung machine. If you’re having scheduled heart bypass-type surgery, your team may take blood samples to see whether these levels can help predict outcomes.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for cardiac surgery with cardiopulmonary bypass?
- Yes. Clin2 currently lists 81 recruiting cardiac surgery with cardiopulmonary bypass studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery with cardiopulmonary bypass trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery with cardiopulmonary bypass trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.