Clinical trials
Cardiac Surgery With Cardiopulmonary Bypass clinical trials
Below are recruiting cardiac surgery with cardiopulmonary bypass clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07094087RecruitingPhase 3
Blood clotting medicine for heart surgery bleeding
This trial tests a medicine called 4F-PCC to stop bleeding during complex heart surgery that uses a heart-lung machine. It could help people who have bleeding problems after the surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT04795193Enrolling by invitation
Minithoracotomy vs open surgery for multiple blocked heart arteries
This trial compares two types of bypass surgery for people with multiple blocked heart arteries, to see which one better improves quality of life and how well the bypasses stay open. You may be assigned based on your preferences, and the study also tracks heart scan and follow-up results.
Beijing, Beijing MunicipalityAges 25–85 - NCT03469440Recruiting
Targeted oxygen monitoring during children’s heart surgery
This trial tests whether a goal-focused monitoring approach can help optimize oxygen levels in the blood during children’s heart surgery using a heart-lung machine. It may help clinicians adjust care more precisely during surgery.
São PauloAges Up to 14 years - NCT06702553RecruitingPhase 3
Nitric oxide to reduce support after heart surgery
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
Boston, MassachusettsAges 18 years+ - NCT06632613RecruitingPhase 2
Trial of ENN0403 to prevent kidney injury after heart surgery
This study tests a new drug (ENN0403) given during heart surgery to see if it prevents acute kidney injury—a sudden drop in kidney function. The trial is for people who are already at higher risk due to their specific heart surgery and other health factors.
ShanghaiAges 18–85 - NCT07683299Recruiting
New heart monitoring during bypass surgery
This study tests a new way to monitor your heart and blood flow during heart surgery that uses a heart-lung machine. The goal is to see if this integrated approach helps doctors make better decisions during the operation.
Medellín, AntioquiaAges 18 years+ - NCT06109155RecruitingPhase 4
Comparing medications to reduce bleeding in heart surgery
This trial tests two medicines—ACT (a blood thinner) and tranexamic acid (a medicine to reduce bleeding)—to see which is better at controlling bleeding during heart surgery. It is for adults having planned heart surgery with a heart-lung machine.
TaichungAges 18 years+ - NCT07354841Recruiting
Testing safety of heart-lung machine tubes
This study tests two types of tubes used during heart surgery to connect you to a heart-lung machine. It aims to see if they work safely and effectively.
Bari, BAAges 18 years+ - NCT07518524Recruiting
Fast Recovery After Heart Valve Surgery
This trial compares two recovery approaches after heart valve surgery: one that wakes you up very quickly in the operating room, and one that's slightly less aggressive. Both use techniques that avoid large chest incisions. The goal is to see which approach gets you breathing on your own sooner and helps you recover faster.
Legnano, ItalyAges 18 years+ - NCT06930443Recruiting
Oxygen use and organ injury after heart-lung bypass surgery
This trial looks at how oxygen is used during heart surgery that uses a heart-lung machine, and whether low oxygen levels can lead to organ damage. It may help doctors better understand how to protect patients during surgery.
Uppsala, SwedenAges 18 years+ - NCT06673953Recruiting
Breathing training for heart surgery recovery with neck posture problems
This trial tests whether a breathing exercise device can improve heart and lung function in men who had heart bypass surgery at least 3 months ago and also have neck pain from poor posture. It may help you breathe better and feel stronger after surgery.
Giza, Giza GovernorateAges 45–55 - NCT06984276Recruiting
Nerve blocks for pain relief in children having heart surgery
This study compares two different ultrasound-guided numbing injections (pectoral nerve block vs. transverse thoracic plane block) to see which provides better pain control for children aged 6 months to 7 years undergoing heart surgery through a chest incision with a heart-lung machine.
CairoAges 6 months–7 years - NCT07744009Recruiting
Awake breathing support for heart valve surgery
This trial tests a new anesthesia method that lets you breathe on your own during heart valve surgery, instead of using a breathing tube. It aims to see if this approach is safer and helps you recover faster than standard anesthesia.
Guangzhou, GuangdongAges 18 years+ - NCT07324694Recruiting
Stable blood pressure during heart surgery and recovery
This study looks at how changes in blood pressure during heart surgery affect recovery. If you are having scheduled heart surgery with a heart-lung machine, you may be able to join.
Diyarbakır, DiyarbakırAges 18 years+ - NCT03302195Recruiting
Heparin and bypass blood management for obese heart surgery
This trial studies the best way to manage blood thinning (anticoagulation) during heart surgery that uses a heart-lung machine in people with obesity. It may help reduce blood-clotting and bleeding complications by comparing different care strategies.
Québec, QuebecAges 18 years+ - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT05189262Recruiting
Study of blood changes during heart surgery bypass
This study looks at whether a machine used during heart surgery (cardiopulmonary bypass) causes red blood cells to break down. The goal is to better understand these blood changes and what they might mean for patients during and after surgery.
Baltimore, MarylandAges 18–88 - NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT05817929Recruiting
Angiopoietin levels and outcomes after heart bypass surgery
This study looks at how a blood protein called angiopoietin relates to recovery and complications after heart surgery that uses a heart-lung machine. If you’re having scheduled heart bypass-type surgery, your team may take blood samples to see whether these levels can help predict outcomes.
AmiensAges 18 years+ - NCT05996120Recruiting
Finding the best temperature during heart-lung machine surgery
This study looks at the best body temperature to use during heart surgery when a heart-lung machine is needed. You may be able to join if you are having bypass surgery or valve repair, your risk score is moderate or higher, and your surgery is not an emergency.
Leicester, LeicestershireAges 18 years+ - NCT06096116RecruitingPhase 3
Trial of a blood product for heparin resistance during heart surgery
This study tests a blood-derived medicine (antithrombin) to help people who do not respond well to the blood thinner heparin during heart surgery. It aims to make surgery safer by improving blood thinning.
Stanford, CaliforniaAges 18–85 - NCT06279793RecruitingPhase 2
Fish oil for recovery after high-risk heart surgery
This trial tests if giving fish oil through a vein before and after heart surgery can help patients recover faster. It is for people who have a high risk of complications during surgery.
AugsburgAges 18 years+ - NCT06705855Recruiting
Predicting kidney injury after heart surgery using skin sensors
This study tests whether a special light-based monitor on your skin (near your kidney and arm) can predict kidney injury after heart surgery. It aims to help doctors protect your kidneys during and after the procedure.
Salt Lake City, UtahAges 18 years+ - NCT06786416Recruiting
Monitoring to prevent kidney injury after heart surgery
This trial is testing a new monitoring system that tracks blood flow and other vital signs during heart surgery to help prevent kidney damage afterward.
San Donato Milanese, MilanoAges 18 years+
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Common questions
- Are there clinical trials for cardiac surgery with cardiopulmonary bypass?
- Yes. Clin2 currently lists 81 recruiting cardiac surgery with cardiopulmonary bypass studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery with cardiopulmonary bypass trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery with cardiopulmonary bypass trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.