Clinical trials
Cardiac Surgery clinical trials
Below are recruiting cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 295 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07030166Recruiting
Predicting kidney injury risk after non-cardiac surgery
This trial uses machine learning to predict the risk of acute kidney injury (AKI) after non-cardiac surgery. If you are 18 or older and having this type of surgery, it may help understand your risk and guide care.
NanjingAges 18 years+ - NCT06128330RecruitingPhase 4
Bedside test for bleeding prevention drug in heart surgery
This study tests a quick bedside measurement of how well the drug tranexamic acid works to prevent bleeding during heart surgery. It may help doctors give the right dose to reduce blood loss.
BernAges 18–90 - NCT06405516Recruiting
Platelet function after heart surgery
This study watches how well platelets (cells that help blood clot) work in people who have high-risk heart surgery using a heart-lung machine for more than 2 hours. The goal is to learn more about bleeding risks after surgery.
BernAges 18 years+ - NCT06968936Recruiting
Long-term outcomes of pre-surgery iron therapy
This study looks at long-term results of giving iron before major heart surgery to people with low iron levels. It aims to see if this treatment helps recovery and outcomes.
Hangzhou, ZhejiangAges 18–85 - NCT06952387Recruiting
Personalized blood pressure for high-risk surgery patients
This study tests whether personalized blood pressure management during and after major surgery can reduce complications and death in older adults with heart or blood vessel risks. It aims to find the safest blood pressure targets for each patient.
Guangzhou, GuangdongAges 65–90 - NCT06814951Recruiting
Breathing & movement technique after heart bypass surgery
This study tests a special breathing and movement technique called the Thoraco-abdominal Rebalance Method to see if it helps people recover faster after heart bypass surgery.
Porto Alegre, Rio Grande do SulAges 35 years+ - NCT06722196RecruitingPhase 3
Amiodarone patch to prevent afib after heart surgery
This trial tests a biodegradable patch that slowly releases amiodarone directly onto the heart during surgery. It aims to prevent atrial fibrillation, a common irregular heartbeat after heart surgery.
Changchun, JinlinAges Any age - NCT06460519Recruiting
Comparing wrist and groin blood pressure in shock patients
This study looks at how blood pressure readings differ between the wrist and the groin in people with severe low blood pressure (shock) who are not recovering from heart surgery. It aims to help doctors better understand and treat shock by comparing these two measurements.
BronAges 18–99 - NCT06324461RecruitingPhase 4
GLP-1 drug to protect heart after non-emergency surgery
This study tests whether a GLP-1 receptor agonist (a medication used for diabetes and weight loss) can reduce heart damage during or after planned non-cardiac surgery. It may help patients with heart risk undergoing intermediate to high-risk procedures.
Hong Kong, Hong Kong SARAges 18 years+ - NCT06322810Recruiting
Pain relief methods for open heart surgery: ESP vs PIFB
This study compares two ways to manage pain after open-heart surgery. It looks at using an injection near the spine (ESP block) versus a needle placed through the chest wall (PIFB) to help reduce pain and the need for strong pain medicines.
Taichung, TaiwanAges 18 years+ - NCT06271265RecruitingPhase 1
Testing EXPAREL for pain after heart surgery in children
This study tests a long-acting pain medicine (EXPAREL) given during heart surgery to see how it works in young children. The goal is to help control pain after surgery with fewer side effects.
Indianapolis, IndianaAges birth–6 years - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT06096116RecruitingPhase 3
Trial of a blood product for heparin resistance during heart surgery
This study tests a blood-derived medicine (antithrombin) to help people who do not respond well to the blood thinner heparin during heart surgery. It aims to make surgery safer by improving blood thinning.
Stanford, CaliforniaAges 18–85 - NCT04164173Recruiting
Breathing therapies after heart surgery for lung overinflation
This study looks at breathing (respiratory) therapies to help after certain heart surgeries that can cause the lungs to feel overly inflated. If you’re eligible, you may receive and be assessed for how well these breathing treatments work during your recovery.
Dallas, TexasAges 18–80 - NCT06054360Recruiting
Predicting irregular heartbeat after heart bypass surgery
This study uses an ultrasound test of the heart's right atrium to see if it can predict who will develop an irregular heartbeat (atrial fibrillation) after planned coronary bypass surgery. If you are scheduled for this surgery and have no history of atrial fibrillation, you may be able to join.
AmiensAges 18 years+ - NCT06012760Recruiting
Can iron and vitamin C reduce transfusions during heart surgery?
This trial is testing whether giving iron plus vitamin C before heart surgery can reduce the need for blood transfusions. It is for people with low iron and anemia who are scheduled for bypass or valve surgery.
Hangzhou, ZhejiangAges 18 years+ - NCT05999721Recruiting
Nerve block for better breathing after heart surgery
This trial is testing a nerve block (a numbing injection) placed near the breastbone to see if it helps your lungs work better after heart surgery. If you are having planned heart surgery through a breastbone cut, you may be able to join.
Petah TikvaAges 18 years+ - NCT05972356Recruiting
How heart relaxation affects outcomes in heart surgery
This study looks at whether a measurement of how well the heart relaxes helps predict outcomes after heart surgery. It focuses on patients treated in Amsterdam UMC and uses care data to understand who may be at higher or lower risk.
Amsterdam, North HollandAges 18 years+ - NCT05824260Recruiting
Study of risk factors for complications after major surgery
This study looks at patients who've had major abdominal, bone, or blood-vessel surgery to understand what factors make some people more likely to have complications afterward. It analyzes information already collected from hospitals to help doctors better predict and prevent problems.
AmiensAges 18 years+ - NCT05841056RecruitingPhase 3
Short-term heart rhythm medication after heart surgery
This study tests whether giving a short course of a medication called amiodarone after heart surgery helps prevent or control new irregular heartbeats (atrial fibrillation) and helps you leave the hospital sooner.
Hamilton, OntarioAges 18 years+ - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05573633Recruiting
Smartwatch test to detect irregular heartbeats after heart surgery
This study checks whether a smartwatch can spot an irregular heartbeat called atrial fibrillation soon after on-pump heart surgery. If the smartwatch works well, it could help clinicians find the problem earlier after surgery.
AmiensAges 18 years+
Hear when a new Cardiac Surgery trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cardiac surgery?
- Yes. Clin2 currently lists 295 recruiting cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.