Clinical trials
Cardiac clinical trials
Below are recruiting cardiac clinical trials, each written for real people, not researchers. We’re tracking 1,296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05965258Recruiting
Classify mitral regurgitation using heart scans
This study uses heart imaging to better understand different types of mitral valve leak (mitral regurgitation) and how it relates to heart pumping function. Results may help doctors match people to the most appropriate care based on scan “patterns.”
Cleveland, OhioAges 18 years+ - NCT05262907Recruiting
Study of heart imaging in people with one pumping ventricle
This study uses routine heart scans (either echocardiogram or MRI) to better understand single-ventricle heart conditions. It may help improve how doctors evaluate and monitor your heart over time.
Durham, North CarolinaAges Any age - NCT06096116RecruitingPhase 3
Trial of a blood product for heparin resistance during heart surgery
This study tests a blood-derived medicine (antithrombin) to help people who do not respond well to the blood thinner heparin during heart surgery. It aims to make surgery safer by improving blood thinning.
Stanford, CaliforniaAges 18–85 - NCT06096246Recruiting
Comparing treatments for persistent atrial fibrillation
This study compares two treatments for persistent atrial fibrillation (AF) that lasts more than 7 days but less than 2 years: electrical cardioversion (a shock to reset your heart rhythm) versus catheter ablation (using radio waves to fix the heart's electrical pathways). It aims to find which option works better for patients like you.
LondonAges 18–85 - NCT04164173Recruiting
Breathing therapies after heart surgery for lung overinflation
This study looks at breathing (respiratory) therapies to help after certain heart surgeries that can cause the lungs to feel overly inflated. If you’re eligible, you may receive and be assessed for how well these breathing treatments work during your recovery.
Dallas, TexasAges 18–80 - NCT06077201Recruiting
Home-based heart rehab after valve procedure
This study tests a home-based exercise program using a mobile app and activity tracker for people who have had a heart valve procedure. It aims to help you safely recover and improve your fitness at home.
Nashville, TennesseeAges 18 years+ - NCT06077422Enrolling by invitationPhase 2/Phase 3
Comparing two pain blocks for heart surgery recovery
This trial compares two types of pain blocks (Exparel vs. Marcaine) given during heart surgery to see which one provides better pain relief. If you are scheduled for a heart surgery through a small or full chest incision, you may be able to join.
New Brunswick, New JerseyAges 18 years+ - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years - NCT06078683Recruiting
Ketone drink for exercise and heart health in type 2 diabetes
This study tests whether a special ketone drink can improve exercise ability and heart function in people with type 2 diabetes. Participants will have two treadmill exercise tests and heart MRI scans to see how the drink affects their performance and cardiac efficiency.
Columbus, OhioAges 18–80 - NCT06070662Recruiting
New MRI test for small heart vessel disease
This study tests a new way to diagnose small blood vessel disease in the heart using an MRI scan during a stress test. It is for people who are already participating in a larger heart imaging study and are scheduled for a catheter procedure.
Leicester, LeicestershireAges 18 years+ - NCT05055830Recruiting
Study blood drug levels in critically ill children
This trial measures how the study medicines move through the body and how they affect the child in the Pediatric Cardiac Intensive Care Unit. It may help doctors choose safer and better dosing for critically ill children.
Durham, North CarolinaAges birth–20 years - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80 - NCT06034392Enrolling by invitation
CHAMP app study for kids with complex heart conditions
This study tests whether using a mobile app to monitor children with complex health conditions at home can help their care team. Families will use the app to share health information instead of only in clinic visits.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT06054360Recruiting
Predicting irregular heartbeat after heart bypass surgery
This study uses an ultrasound test of the heart's right atrium to see if it can predict who will develop an irregular heartbeat (atrial fibrillation) after planned coronary bypass surgery. If you are scheduled for this surgery and have no history of atrial fibrillation, you may be able to join.
AmiensAges 18 years+ - NCT04713657RecruitingPhase 1
Beta-blocker study for heart muscle function in young babies
This trial tests whether a beta-blocker called propranolol can improve how well heart muscle cells work in very young babies with certain congenital heart conditions. It mainly looks at safety and how the medicine affects the heart, which could help guide future treatments.
New York, New YorkAges 4 weeks–2 months - NCT06018519Recruiting
Measuring outcomes for creatine transporter deficiency
This study aims to find the best ways to measure how creatine transporter deficiency (CTD) affects people. It includes both males and females with CTD, as well as healthy volunteers, to compare results and develop better tests.
BronAges 2–60 - NCT06025123Recruiting
Cooling treatment for cardiac arrest before hospital
This trial tests whether cooling the brain through the nose right after a cardiac arrest improves survival. Paramedics will start a cooling treatment within 20 minutes of arriving, and it may help protect your brain while you are unconscious.
GrazAges 18–79 - NCT06012760Recruiting
Can iron and vitamin C reduce transfusions during heart surgery?
This trial is testing whether giving iron plus vitamin C before heart surgery can reduce the need for blood transfusions. It is for people with low iron and anemia who are scheduled for bypass or valve surgery.
Hangzhou, ZhejiangAges 18 years+ - NCT05999721Recruiting
Nerve block for better breathing after heart surgery
This trial is testing a nerve block (a numbing injection) placed near the breastbone to see if it helps your lungs work better after heart surgery. If you are having planned heart surgery through a breastbone cut, you may be able to join.
Petah TikvaAges 18 years+ - NCT05979870Enrolling by invitation
AI-enhanced heart MRI for valve disease
This study uses artificial intelligence to improve MRI scans for people with aortic or pulmonary valve disease who are scheduled for valve surgery or a non-surgical valve procedure. It aims to help doctors better assess heart function before treatment.
Gothenburg, GothenburgAges 1 week–18 years - NCT05994014Recruiting
Comparing two heart scans for artery blockages
This study compares two types of heart scans to see which one better finds blockages in the arteries of people with chest discomfort or shortness of breath when active. You will have both a special CT scan and a PET/CT scan to check the health of your heart arteries.
Baltimore, MarylandAges 18 years+ - NCT05951088Recruiting
Mobile app follow-up for heart patients with AF or heart failure
This study tests a smartphone or tablet app that helps keep track of follow-up care for people with certain heart rhythm problems (AF/atrial flutter) and/or heart failure. If you join, you would be followed long-term to see whether the app can support ongoing care.
Edegem, AntwerpAges 18 years+ - NCT05972356Recruiting
How heart relaxation affects outcomes in heart surgery
This study looks at whether a measurement of how well the heart relaxes helps predict outcomes after heart surgery. It focuses on patients treated in Amsterdam UMC and uses care data to understand who may be at higher or lower risk.
Amsterdam, North HollandAges 18 years+ - NCT05954559RecruitingPhase 4
MRI study testing a strong-contrast heart scar scan agent
This Phase 4 study checks whether a stronger MRI contrast dye (given in a higher “relaxivity” form) can better help doctors assess heart muscle scar tissue. You may be eligible if you already joined a prior similar MRI contrast study and can safely undergo another heart MRI.
Baltimore, MarylandAges 21 years+
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Common questions
- Are there clinical trials for cardiac?
- Yes. Clin2 currently lists 1,296 recruiting cardiac studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.