Clinical trials
Cardiac clinical trials
Below are recruiting cardiac clinical trials, each written for real people, not researchers. We’re tracking 1,291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06325280Recruiting
Exercise MRI for Kids with Heart Conditions
This study uses an MRI while exercising to check heart and lung fitness in children with heart disease. It helps doctors learn more about how to care for kids who have had a heart transplant or were born with heart problems.
Edmonton, AlbertaAges 10–18 - NCT05842603Recruiting
Lifestyle program to help people with MPN move more
This pilot study tests a lifestyle and movement program for adults with certain myeloproliferative neoplasms (MPNs), aiming to improve well-being through safe exercise habits. You may be considered if you have an MPN and at least one heart-related risk factor.
Boston, MassachusettsAges 18 years+ - NCT06291675Recruiting
Hormone therapy's effect on heart and organ fat
This study uses MRI scans to see how gender-affirming hormone therapy affects heart muscle, heart function, and fat in the heart, liver, and pancreas. It may help us understand long-term health effects of hormone therapy.
Vienna, State of ViennaAges 18 years+ - NCT06262126Recruiting
Virtual reality for non-cardiac chest pain
This study tests whether virtual reality can help people who have chest pain that is not caused by the heart. You will use a VR headset to see if it reduces your symptoms.
Jacksonville, FloridaAges 18 years+ - NCT06271265RecruitingPhase 1
Testing EXPAREL for pain after heart surgery in children
This study tests a long-acting pain medicine (EXPAREL) given during heart surgery to see how it works in young children. The goal is to help control pain after surgery with fewer side effects.
Indianapolis, IndianaAges birth–6 years - NCT06239974Recruiting
Vericiguat for chest pain from small vessel heart disease
This study tests whether a medication called vericiguat can improve chest pain caused by problems in the tiny blood vessels of the heart (not by large blockages). You may be a candidate if you have stable chest pain, are 40–75, and have had tests showing your heart's small vessels aren't working well.
Hong KongAges 40–75 - NCT06251778Recruiting
National study of ATTR heart amyloid patients on tafamidis
This study follows patients with a specific type of heart amyloidosis (wild-type ATTR) who are taking or could start the drug tafamidis. It aims to learn more about how the condition and treatment affect people over time.
PaviaAges 18–99 - NCT06250985RecruitingPhase 3
New treatment for infected heart device: quick re-implant
This trial tests if a new, faster approach to replacing an infected pacemaker or defibrillator is safe. If you have a heart device infection and meet recovery milestones, you might be able to get a new device sooner than usual.
Frederiksberg, CopenhagenAges 18–110 - NCT06245681Recruiting
How Hormone Therapy Affects the Heart and Liver
This study looks at how cross-sex hormone treatment affects the heart and fat in the liver. It aims to help understand the safety of hormone therapy in transgender individuals.
Vienna, State of ViennaAges 18–99 - NCT04075084Recruiting
Watching outcomes of routine home monitoring after a heart monitor implant
This registry study follows people who get a BIOTRONIK implantable heart monitor and use home monitoring. It looks at how routine care and at-home check-ins work in real life, which may help improve support and tracking over time.
AdelaideAges 18 years+ - NCT02708134Recruiting
Study of CPR quality in children and young adults
This trial looks at how well CPR (chest compressions) is done during an emergency resuscitation in children and young adults. The goal is to understand what helps improve care during life-saving resuscitation.
Los Angeles, CaliforniaAges birth–18 years - NCT06220032RecruitingPhase 3
Preventing heart damage from chemotherapy in lymphoma
This trial tests if the drug dexrazoxane can protect the heart during chemotherapy for a type of lymphoma called DLBCL. It may be an option for patients starting a standard treatment regimen known as R-CHOP.
's-HertogenboschAges 18 years+ - NCT06220006Recruiting
Comparing heart tissue burns for atrial fibrillation treatment
This study compares two ways to create small burns in the heart tissue to fix an irregular heartbeat (atrial fibrillation). It uses a special MRI to see how well each method works.
Barcelona, CataloniaAges 18 years+ - NCT04983823Recruiting
Study aims to improve long-term heart effects after COVID
This trial looks at how persistent heart-related changes after a past COVID infection may be affected by study treatments. It mainly seeks people who are stable enough for follow-up visits and heart imaging, and who are not already on the specific heart medications required.
Melbourne, VictoriaAges 50–85 - NCT06183437RecruitingPhase 4
Can I stop heart meds after cancer therapy?
This trial tests whether it is safe to stop taking heart failure medications in people who developed heart weakness after cancer treatment but whose heart function has since recovered. It aims to see if stopping these drugs leads to any worsening of heart health.
Los Angeles, CaliforniaAges 18 years+ - NCT06197165Recruiting
Shiatsu for amyloidosis symptoms and quality of life
This study tests whether shiatsu (a gentle Japanese touch therapy) can improve symptoms and quality of life for people with amyloidosis. If you have a bothersome symptom like pain, shortness of breath, or anxiety, this trial may help you feel better.
CréteilAges 18 years+ - NCT06196307Recruiting
Early warning system for sudden chest pain
This trial is for people who come to the emergency room with new or worsening chest pain not caused by an injury. It aims to build an early warning system to better classify and treat chest pain.
Beijing, ChaoyangAges 18 years+ - NCT06165081Recruiting
Emergency care after cardiac arrest and short-term outcomes
This study looks at how care in the emergency room after a cardiac arrest affects short-term recovery. It may help doctors find better ways to treat patients whose hearts have stopped outside the hospital.
Hsinchu, Hsinchu CityAges 20 years+ - NCT06179329Recruiting
Comparing two types of heart bypass grafts in women
This trial compares two types of grafts (the radial artery from the arm and a vein from the leg) used in women having heart bypass surgery for the first time. It aims to see which graft works better and stays open longer.
São Paulo, São PauloAges 18–75 - NCT03418961RecruitingPhase 3
Study of heart-risk management for metastatic HER2 breast cancer
This trial follows people with metastatic HER2-positive breast cancer who are at higher risk for heart damage while on HER2-targeted therapy. Some participants are randomly assigned to different monitoring/heart-protection approaches to see what best helps keep the heart safe.
Anchorage, AlaskaAges 18 years+ - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT06149195Enrolling by invitation
Heart scan for managing heart failure
This trial tests a special heart scan (18F-MFBG) to see if it can help doctors better manage heart failure. You may qualify if you have chronic heart failure with a weak heart pump and are planning to get a defibrillator.
Chengdu, SichuanAges 18–80 - NCT05965258Recruiting
Classify mitral regurgitation using heart scans
This study uses heart imaging to better understand different types of mitral valve leak (mitral regurgitation) and how it relates to heart pumping function. Results may help doctors match people to the most appropriate care based on scan “patterns.”
Cleveland, OhioAges 18 years+ - NCT05262907Recruiting
Study of heart imaging in people with one pumping ventricle
This study uses routine heart scans (either echocardiogram or MRI) to better understand single-ventricle heart conditions. It may help improve how doctors evaluate and monitor your heart over time.
Durham, North CarolinaAges Any age
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Common questions
- Are there clinical trials for cardiac?
- Yes. Clin2 currently lists 1,291 recruiting cardiac studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.