Clinical trials
Chest Pain clinical trials
Below are recruiting chest pain clinical trials, each written for real people, not researchers. We’re tracking 49 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05174247Recruiting
Using FFRct to guide tests for stable chest pain
This study checks whether adding FFRct analysis (a special computer-based estimate of blood flow from a CT scan) improves the diagnostic pathway for people with stable chest pain. It may help doctors decide what to do next by clarifying how much a narrowed heart artery is truly limiting blood flow.
Rotterdam, South HollandAges 18 years+ - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT05897632Recruiting
Rapid chest-pain evaluation for moderate-risk adults
This trial tests a faster “ambulatory rapid evaluation” approach for adults who come in with chest pain that could be heart-related, but is not clearly an emergency. It may help doctors quickly sort who is safe to send home and who needs urgent heart testing, using specific ECG and blood test results.
Detroit, MichiganAges 21 years+ - NCT06149819Recruiting
Chest pain nurse track for emergency care
This trial is testing a nurse-led care pathway for people who come to the emergency room with chest pain that is not caused by an injury. The goal is to see if this approach can improve care and speed up the process.
Grenoble, GrenobleAges 18 years+ - NCT06196307Recruiting
Early warning system for sudden chest pain
This trial is for people who come to the emergency room with new or worsening chest pain not caused by an injury. It aims to build an early warning system to better classify and treat chest pain.
Beijing, ChaoyangAges 18 years+ - NCT06493175Recruiting
Large language model for emergency chest pain triage
This study tests whether a large language model (a type of artificial intelligence) can help sort patients with chest pain in the emergency room. It aims to make triage faster and more accurate for adults coming in with chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06693063Recruiting
Follow-up after chest pain in emergency
This study looks at whether seeing your regular doctor after a hospital visit for chest pain can help prevent future emergency visits. If you had chest pain and went to the Emile Roux emergency room, you may be able to join.
Le Puy-en-VelayAges 18 years+ - NCT07192965Recruiting
Heart scan without ECG for chest pain with high troponin
This trial tests if a coronary CT scan (without needing an ECG) can safely guide care for people who come to the emergency room with chest pain and a high troponin level. It aims to see if this approach works as well as standard tests.
JetteAges 30 years+ - NCT04748237Recruiting
CT heart scan for intermediate-risk chest pain
This study tests whether a special heart CT scan can help evaluate the cause of chest pain in people at intermediate risk for blocked heart arteries. It may help doctors decide what to do next after an emergency room visit.
StockholmAges 18 years+ - NCT06262126Recruiting
Virtual reality for non-cardiac chest pain
This study tests whether virtual reality can help people who have chest pain that is not caused by the heart. You will use a VR headset to see if it reduces your symptoms.
Jacksonville, FloridaAges 18 years+ - NCT07579182RecruitingPhase 1
How Exercise and Hormones Affect Pain in Women
This study looks at how exercise affects pain and hormone levels in women. Researchers will ask you about your activity level, do some physical tests, and measure how your body responds to exercise over several visits.
Houston, TexasAges 18–60 - NCT05344612Recruiting
Testing CT scan first to guide treatment for chest pain
This trial studies whether doing a special heart scan (CTCA) right away can better guide treatment for people with chest pain who might have coronary artery disease. It compares this “scan-first” strategy to standard care to see which approach leads to better outcomes and fewer unnecessary procedures.
Amsterdam, North HollandAges 18 years+ - NCT06239974Recruiting
Vericiguat for chest pain from small vessel heart disease
This study tests whether a medication called vericiguat can improve chest pain caused by problems in the tiny blood vessels of the heart (not by large blockages). You may be a candidate if you have stable chest pain, are 40–75, and have had tests showing your heart's small vessels aren't working well.
Hong KongAges 40–75 - NCT06669884Recruiting
New ECG method to quickly sort chest pain in ER
This study tests a new ECG-based technology that may help doctors more quickly sort out the cause of your chest pain in the emergency room. If you have chest pain that needs checking, this tool could help decide how urgent your care is.
Jinan, ShandongAges 18 years+ - NCT05809648Enrolling by invitation
Testing a special scan to better diagnose heart blood-flow problems
This study checks whether a magnet-based heart scan (magnetocardiography) can more accurately find “true ischemia,” which means reduced blood flow to the heart, in people who come to the emergency room with chest pain. It aims to help doctors tell which chest pain is truly from heart blood-flow problems.
Rochester, MinnesotaAges 18 years+ - NCT07435168Recruiting
Chest pain and hidden cardiac amyloidosis study
This study looks for signs of a condition called cardiac amyloidosis in people who have chest pain but no blocked heart arteries. It aims to find hidden cases that might be missed with standard tests.
CopenhagenAges 65 years+ - NCT04691037Recruiting
CT heart scan to guide care for stable chest pain
This trial studies whether a CT heart scan (CCTA) can better guide treatment decisions for people with stable chest pain caused by blocked heart arteries. It may help your care team choose the next best step based on scan results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05865327Recruiting
Nerve freezing for rib-fracture pain using ultrasound guidance
This trial tests whether freezing a specific nerve (a “cryoneurolysis” treatment) through a catheter can better control pain from traumatic rib fractures. It’s offered to adults who have rib fractures soon after hospital admission and can use a pain control method called patient-controlled regional analgesia.
Toronto, OntarioAges 18–100 - NCT06520150Recruiting
Comparing two numbing methods for S-ICD heart device placement
This study compares two ways of numbing the chest area (regional anesthesia) for people getting an S-ICD heart device. The goal is to find which method works better and is safer for patients who are at higher risk for general anesthesia.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT06718374Recruiting
Chest pain differences in diabetic vs non-diabetic patients
This study compares how chest pain feels in people with and without diabetes after a heart attack. It aims to understand if diabetes changes the symptoms, which could help doctors diagnose faster.
Asyut, Asyut GovernorateAges Any age - NCT07626060Recruiting
AI Tools for Chest Pain Risk Assessment
This study tests whether artificial intelligence (AI) programs can accurately calculate a chest pain risk score to help doctors decide who needs urgent heart tests. You'll be monitored for 30 days to see if the AI's predictions were correct.
Istanbul, IstanbulAges 18 years+ - NCT06949059RecruitingPhase 1/Phase 2
Hydromorphone for acute chest pain relief
This trial tests a quick-acting pain medicine (hydromorphone) given through a vein to treat severe chest pain. It may be an option for people experiencing acute pain who haven't been helped by other medicines.
Nanjing, JiangsuAges 18–64 - NCT07258290Recruiting
Freesolve Magnesium Scaffold for Heart Artery Blockages
This trial tests a new dissolvable magnesium scaffold to treat blockages in heart arteries. It is designed for people with stable heart pain or certain recent heart attacks, and it aims to open blocked arteries and then slowly dissolve over time.
Washington D.C., District of ColumbiaAges 18–80 - NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age
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Common questions
- Are there clinical trials for chest pain?
- Yes. Clin2 currently lists 49 recruiting chest pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chest pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chest pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.