Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT05780099Recruiting
Study of patients treated in internal medicine clinics
This observational study follows people receiving care in Internal Medicine at San Raffaele Hospital to better understand what kinds of conditions they have. It does not test a new treatment, but your information may help improve future care.
MilanAges 18 years+ - NCT06795763Enrolling by invitation
New imaging & catheter system for blocked heart arteries
This trial tests a new imaging and catheter system to treat chronic total blockages in heart arteries. If you still have chest pain or other symptoms despite medical therapy, this study may help open the blockage and improve blood flow.
Atlanta, GeorgiaAges 18 years+ - NCT07187479Recruiting
Testing a new insulin approach for kidney disease and diabetes
This study tests a new approach to help your body use insulin better, which may improve blood sugar control and slow down kidney disease. It is for people with advanced chronic kidney disease and type 2 diabetes who are not yet on dialysis.
Phoenix, ArizonaAges 18 years+ - NCT05333471RecruitingPhase 1/Phase 2
Fecal transplant for chronic bowel inflammation in CGD
This study tests whether transplanting stool microbiome (fecal microbiota transplant) can improve chronic colitis in people with chronic granulomatous disease (CGD). It aims to reduce bowel inflammation and symptoms by changing gut bacteria.
Bethesda, MarylandAges 10–60 - NCT05844462RecruitingPhase 3
Tadalafil for severe lung blood-pressure problems from COPD
This study tests whether tadalafil can improve outcomes for people with severe pulmonary hypertension caused by COPD (chronic lung disease). It compares how you do with tadalafil versus standard care, focusing on breathing symptoms and how well your heart and lungs cope.
Le Kremlin-Bicêtre, FranceAges 18–85 - NCT07750821Recruiting
Balance training for people with COPD
This study looks at whether adding balance training after standard pulmonary rehabilitation helps people with COPD improve their balance and reduce the risk of falls. It may help you feel more steady and confident in daily activities.
MiddlesbroughAges Any age - NCT03890224Recruiting
Testing breathing support needs in COPD with high CO2
This trial studies how different breathing support strategies affect people with COPD who have high carbon dioxide (CO2) in their blood. It may help care teams choose safer respiratory support after a breathing machine is stopped.
Paris, Île-de-France RegionAges 18 years+ - NCT04427826RecruitingPhase 1/Phase 2
Morphine to prevent early NIV failure in COPD flare-ups
This trial studies whether morphine can help people with a COPD flare-up avoid “non-invasive ventilation” (breathing support through a mask) failing early. The goal is to reduce how often people need escalation of care soon after starting NIV.
Grenoble, Isère, Auvergne-Rhône-AlpesAges 18 years+ - NCT06891677Recruiting
Online therapy and education for COPD
This trial tests a program you can do from home on your computer. It combines talk therapy and education to help you manage your COPD symptoms and feel better.
Norrköping, Östergötland CountyAges 18 years+ - NCT01177618Recruiting
Study of early-onset severe COPD in younger adults
This study looks at people who develop COPD (a long-term lung breathing problem) at a younger age and have severe airflow limitation. It may help researchers better understand COPD in early-onset patients and find ways to improve care for this group.
Boston, MassachusettsAges Any age - NCT06776731Recruiting
Does extra oxygen during rehab help lung disease patients?
This study tests whether breathing extra oxygen during outpatient pulmonary rehabilitation helps people with COPD. Participants will have their oxygen levels checked during exercise to see if extra oxygen improves their rehab results.
Winterthur, Canton of ZurichAges 18 years+ - NCT06798077Recruiting
Chronic Lung Disease and Multiple Health Issues Study
This study follows people with chronic airway diseases like COPD, asthma, or bronchiectasis who were recently hospitalized for a worsening of their condition. It aims to understand how these diseases affect overall health and other medical problems over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07107945RecruitingPhase 3
Study of empagliflozin for children with chronic kidney disease
This trial tests if empagliflozin, a daily pill, is safe and helps children ages 2–17 with chronic kidney disease (CKD). Your child may be eligible if they have reduced kidney function and elevated protein in their urine, and are already on stable kidney treatments.
Birmingham, AlabamaAges 2–17 - NCT05820776Recruiting
Tele-rehabilitation for stable breathing problems
This observational study looks at how tele-rehabilitation affects people with stable chronic breathing problems, especially if breathing limits their activity. It may help your care team understand what kinds of support work best when symptoms are steady.
Toronto, OntarioAges 18 years+ - NCT06466785RecruitingPhase 3
Study of Efepoetin Alfa for anemia in kidney dialysis patients
This study tests a new drug called Efepoetin Alfa to treat anemia in people with chronic kidney disease who are on dialysis. The goal is to see if it can safely raise red blood cell levels and reduce the need for other anemia treatments.
YerevanAges 18 years+ - NCT07741279Recruiting
Enarodustat for anemia in chronic kidney disease patients
This study tests a daily pill that helps people with chronic kidney disease and anemia make more red blood cells, which may reduce the need for other anemia treatments. It is for patients who are not on dialysis and do not plan to start dialysis or have a kidney transplant within the next six months.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Fairhope, AlabamaAges 18 years+ - NCT03633708RecruitingPhase 3
Etelcalcetide for children with dialysis-related overactive parathyroid hormone
This trial studies etelcalcetide in children who have chronic kidney disease and too much parathyroid hormone while on hemodialysis. It aims to safely lower the hormone levels and help manage related bone/mineral problems.
Los Angeles, CaliforniaAges birth–18 years - NCT06712654RecruitingPhase 2
Testing AP306 for high phosphate in dialysis patients
This trial tests a new medication called AP306 for people on hemodialysis who have high blood phosphate. It aims to see if the drug is safe, tolerable, and helps lower phosphate levels.
Huntsville, AlabamaAges 18 years+ - NCT05335603Recruiting
Study of adults with liver conditions linked to fatty liver
This study looks at adults with different long-term liver conditions that are associated with fatty liver. It helps researchers better understand these diseases and factors linked to them.
HvidovreAges 18 years+ - NCT06635590Recruiting
Kidney disease, high potassium, and heart changes
This study looks at how high potassium levels (hyperkalemia) in people with chronic kidney disease may affect the heart. Doctors will use echocardiograms (heart ultrasounds) to check for changes.
AnkaraAges 18 years+ - NCT06838416Recruiting
Study on finerenone for kidney health in type 2 diabetes
This trial tests if a medicine called finerenone can protect kidney function in people with type 2 diabetes and early-to-moderate chronic kidney disease. It may be an option if you are already on blood pressure medication and have some protein in your urine.
Suzhou, JiangsuAges 18 years+ - NCT06940414Recruiting
Study of high potassium in kidney disease patients in community
This study looks at how common high potassium levels are in people with chronic kidney disease who are not on dialysis. It may help find who is at risk and how to prevent it.
Shanghai, Shanghai MunicipalityAges 18 years+
Hear when a new Chronic Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,260 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.