Clinical trials
Chronic Liver Disease clinical trials
Below are recruiting chronic liver disease clinical trials, each written for real people, not researchers. We’re tracking 399 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05791448RecruitingPhase 1
AU409 for advanced liver cancers or liver-spread tumors
This Phase 1 trial studies AU409, a new medicine, for advanced primary liver cancers or other solid tumors mainly in the liver. It aims to find a safe dose and see how well the treatment works for people whose usual options have not worked or are not available.
Los Angeles, CaliforniaAges 18 years+ - NCT06609772Recruiting
Pain education for liver donors after surgery
This trial tests an individualised pain education program to see if it can reduce chronic pain and improve quality of life for living liver donors after their surgery.
Malatya, BattalgaziAges Any age - NCT07600788RecruitingPhase 1
Liver Function and Safety Study of AHB-137 Injection
This study tests how a new investigational drug called AHB-137 moves through your body and affects safety in people with mild-to-moderate liver problems compared to people with normal liver function. The goal is to understand if the drug works safely in people whose livers don't work as well as they should.
Chongqing, Chongqing MunicipalityAges 18–65 - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT07124078RecruitingPhase 2
Study of axatilimab vs. best available therapy for chronic GVHD in children
This trial tests a new drug called axatilimab against the best available standard treatments for children with chronic graft-versus-host disease (cGVHD) that has not responded to at least two prior treatments. It aims to find a better option for managing this condition.
Duarte, CaliforniaAges 2–17 - NCT05905172RecruitingPhase 3
Hydronidone for long-term treatment of hepatitis B scarring
This Phase 3 study tests whether hydronidone capsules can help people with long-term hepatitis B–related liver scarring (fibrosis). It aims to track whether treatment reduces or delays serious liver complications over time.
Beijing, Beijing MunicipalityAges 18–65 - NCT07552727Recruiting
Exercise program for fatty liver disease
This study tests whether a structured exercise program can help reduce fat buildup in the liver for people with overweight or obesity and related conditions like insulin resistance or type 2 diabetes. The goal is to see if regular physical activity improves liver health without medication.
Valdivia, Los Ríos RegionAges 18–59 - NCT06777914Recruiting
Genes linked to rare liver disease and cancer risk
This study looks at whether certain family-related genes make people more likely to develop liver or bile duct cancers without a clear cause. If you had surgery or a transplant for one of these cancers and have had unexplained high liver enzymes or itching, this trial may help find genetic clues.
Bologna, BolognaAges 1 year+ - NCT05439226Recruiting
Diet plan targeting liver fat for type 2 diabetes
This study tests whether a Chinese medical nutrition therapy diet can reduce liver fat and help manage type 2 diabetes in people who also have fatty liver. You may be asked to follow a specific eating plan and keep your diabetes care stable during the study.
Yichang, HubeiAges 18–75 - NCT07632677Recruiting
Testing a liver inflammation score in diabetes and fatty liver
This study tests whether a new scoring method can help doctors identify liver inflammation in patients who have both type 2 diabetes and a fatty liver. The goal is to find an easier, safer way to assess liver health without invasive procedures.
Bengbu, AnhuiAges 18 years+ - NCT07683065Recruiting
Secukinumab treatment in psoriasis patients with liver condition
This study looks at how well secukinumab works for psoriasis patients who also have a type of fatty liver disease called MASLD. It may help doctors understand if this treatment is a good option for people with both conditions.
Badalona, BarcelonaAges 18–100 - NCT06274788Recruiting
Safety study of long-term Omegaven for liver problems from IV nutrition
This study checks if children who need Omegaven for eight weeks or longer develop a lack of essential fats. It is for kids with liver issues caused by IV nutrition who cannot eat or digest food normally.
Fountain Valley, CaliforniaAges 1 day–17 years - NCT07046819RecruitingPhase 2
Tirzepatide for liver disease linked to alcohol use
This trial tests if tirzepatide, a medication that helps with weight and blood sugar, can improve liver health in people with alcohol use disorder who also have fatty liver disease. It aims to reduce liver fat and related risks.
Bethesda, MarylandAges 21–100 - NCT06531824RecruitingPhase 3
Heart and kidney protection study for chronic kidney disease
This study tests a new medicine (BI 690517) combined with empagliflozin to see if it can help protect the heart and kidneys in people with chronic kidney disease. It may slow down kidney disease progression and reduce heart risks.
Huntsville, AlabamaAges 18 years+ - NCT07527910RecruitingPhase 2
Study of ALN-PNP with or without tirzepatide for fatty liver disease
This trial tests a new drug, ALN-PNP, alone or with tirzepatide in people with a specific genetic type of fatty liver disease. It aims to see if the combination reduces liver fat.
Coronado, CaliforniaAges 18–75 - NCT06453915RecruitingEarly Phase 1
Brain PET scan for inflammation in fatty liver disease
This study uses a special PET scan to look for inflammation in the brain related to fatty liver disease. It may help researchers understand how liver health affects brain function.
Sacramento, CaliforniaAges 18 years+ - NCT07185932RecruitingEarly Phase 1
Rifaximin for fatty liver with metabolic issues
This trial tests if rifaximin, a gut-targeted antibiotic, can help people with fatty liver disease who also have metabolic problems like obesity or diabetes. You need a recent fatty liver diagnosis and a liver fat level of at least 8% on an MRI scan.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07381257RecruitingEarly Phase 1
Rifaximin for fatty liver disease
This trial tests if rifaximin, a gut medication, can help reduce liver fat in people with metabolic fatty liver disease. It may be an option if you have at least one metabolic risk factor and a certain amount of liver fat.
ShanghaiAges 18–75 - NCT07592013Enrolling by invitation
Ancestry Supplements for Fatty Liver Disease
This study tests whether a special supplement (made from cacao, nopal, and crickets) can help improve fatty liver disease in people with excess body fat. Fatty liver disease happens when fat builds up in the liver, and this trial investigates whether these natural ingredients can reduce that buildup.
Guadalajara, GuadalajaraAges 18–60 - NCT07280143Recruiting
MASLD risk in breast or colorectal cancer survivors
This study looks at whether breast or colorectal cancer survivors are more likely to develop a liver condition called MASLD (fatty liver disease not caused by alcohol). It uses blood tests, imaging, and possibly an MRI to check liver health.
BernAges 18 years+ - NCT06632457RecruitingPhase 3
Survodutide for NASH/MASH cirrhosis: a phase 3 trial
This study tests an investigational drug called survodutide for people with a type of fatty liver disease (NASH or MASH) that has progressed to cirrhosis. The goal is to see if it can improve liver health.
Peoria, ArizonaAges 18 years+ - NCT07313007Recruiting
Gut bacteria chemicals in fatty liver disease
This study looks at whether the natural chemicals made by your gut bacteria from the food you eat could affect liver fat and health. If you have MASLD (a fatty liver condition), researchers want to measure these gut-produced substances to better understand the disease.
Pierre-BéniteAges 18–80 - NCT07459504RecruitingPhase 2
Smart diets for kids with fatty liver disease
This study compares different diet plans to see which works best to reduce fat in the liver of children and teens with MASLD (a type of fatty liver disease). If your child drinks sugary beverages often and has certain health risks like being overweight or having high cholesterol, this trial may help find a healthy eating plan that works.
Grand Rapids, MichiganAges 11–17 - NCT06968234Recruiting
Liver disease breath test study
This study uses a special breath test to learn about chronic liver disease. If you have liver disease or cirrhosis, you may be able to help by providing a breath sample.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for chronic liver disease?
- Yes. Clin2 currently lists 399 recruiting chronic liver disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic liver disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic liver disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.